2,3,4-Trinitrobenzene-1-sulfonic acid (BioDeep_00000174138)
human metabolite blood metabolite
代谢物信息卡片
2,3,4-Trinitrobenzene-1-sulphonic acid
化学式: C6H3N3O9S (292.9590028)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC(=C(C(=C1[N+](=O)[O-])[N+](=O)[O-])[N+](=O)[O-])S(=O)(=O)O
InChI: InChI=1S/C6H3N3O9S/c10-7(11)3-1-2-4(19(16,17)18)6(9(14)15)5(3)8(12)13/h1-2H,(H,16,17,18)
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Afrooz Saadatzadeh, Fatemeh Atyabi, Mohammad Reza Fazeli, Rassoul Dinarvand, Hossein Jamalifar, Amir Hossein Abdolghaffari, Parvin Mahdaviani, Mirgholamreza Mahbod, Maryam Baeeri, Amir Baghaei, Azadeh Mohammadirad, Mohammad Abdollahi. Biochemical and pathological evidences on the benefit of a new biodegradable nanoparticles of probiotic extract in murine colitis.
Fundamental & clinical pharmacology.
2012 Oct; 26(5):589-98. doi:
10.1111/j.1472-8206.2011.00966.x. [PMID: 21771055] - Duan-yong Liu, Yong-mei Guan, Hai-mei Zhao, Dong-mei Yan, Wen-ting Tong, Pan-ting Wan, Wei-feng Zhu, Hong-ning Liu, Xin-li Liang. The protective and healing effects of Si Shen Wan in trinitrobenzene sulphonic acid-induced colitis.
Journal of ethnopharmacology.
2012 Sep; 143(2):435-40. doi:
10.1016/j.jep.2012.05.060. [PMID: 22751005] - Yi-Tzai Chen, Deshi Shi, Dongfang Yang, Bingfang Yan. Antioxidant sulforaphane and sensitizer trinitrobenzene sulfonate induce carboxylesterase-1 through a novel element transactivated by nuclear factor-E2 related factor-2.
Biochemical pharmacology.
2012 Sep; 84(6):864-71. doi:
10.1016/j.bcp.2012.06.025. [PMID: 22776248] - Maria Angeles Rosillo, Marina Sánchez-Hidalgo, Ana Cárdeno, Marina Aparicio-Soto, Susana Sánchez-Fidalgo, Isabel Villegas, Catalina Alarcón de la Lastra. Dietary supplementation of an ellagic acid-enriched pomegranate extract attenuates chronic colonic inflammation in rats.
Pharmacological research.
2012 Sep; 66(3):235-42. doi:
10.1016/j.phrs.2012.05.006. [PMID: 22677088] - Chun-Hui Bao, Lu-Yi Wu, Huan-Gan Wu, Yin Shi, Hui-Rong Liu, Rong Zhang, Li-Qing Yu, Jin-Hai Wang. Moxibustion inhibits apoptosis and tumor necrosis factor-alpha/tumor necrosis factor receptor 1 in the colonic epithelium of Crohn's disease model rats.
Digestive diseases and sciences.
2012 Sep; 57(9):2286-95. doi:
10.1007/s10620-012-2161-0. [PMID: 22531889] - Jian-Feng Xing, Jian-Ning Sun, Jin-Yao Sun, Cui-Yu You, Kai Dong, Jun Lv, Ya-Lin Dong. Protective effects of 3,4-oxo-isopropylidene-shikimic acid on experimental colitis induced by trinitrobenzenesulfonic acid in rats.
Digestive diseases and sciences.
2012 Aug; 57(8):2045-54. doi:
10.1007/s10620-012-2155-y. [PMID: 22476587] - Tamás Kovács, Gabriella Varga, Dániel Erces, Tünde Tőkés, László Tiszlavicz, Miklós Ghyczy, Mihály Boros, József Kaszaki. Dietary phosphatidylcholine supplementation attenuates inflammatory mucosal damage in a rat model of experimental colitis.
Shock (Augusta, Ga.).
2012 Aug; 38(2):177-85. doi:
10.1097/shk.0b013e31825d1ed0. [PMID: 22576006] - Tamás Kovács, Gabriella Varga, Dániel Erces, Tünde Tőkés, László Tiszlavicz, Miklós Ghyczy, László Vécsei, Mihály Boros, József Kaszaki. [Comparative study of novel therapeutic possibilities in animal experimental model of inflammatory bowel disease].
Magyar sebeszet.
2012 Aug; 65(4):191-7. doi:
10.1556/maseb.65.2012.4.4. [PMID: 22940387] - P Martínez-Moya, M Ortega-González, R González, A Anzola, B Ocón, C Hernández-Chirlaque, R López-Posadas, M D Suárez, A Zarzuelo, O Martínez-Augustin, F Sánchez de Medina. Exogenous alkaline phosphatase treatment complements endogenous enzyme protection in colonic inflammation and reduces bacterial translocation in rats.
Pharmacological research.
2012 Aug; 66(2):144-53. doi:
10.1016/j.phrs.2012.04.006. [PMID: 22569414] - Zi-Hui Li, Jian Wang, Rong-Lin Cai, You-Wen Wang, Jian-Peng Hu. [Establishment and evaluation of a rat model of ulcerative colitis with syndrome of dampness stagnancy due to spleen deficiency].
Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine.
2012 Aug; 10(8):918-24. doi:
10.3736/jcim20120813. [PMID: 22883409] - Tatsuo Hashimoto, Thomas Perlot, Ateequr Rehman, Jean Trichereau, Hiroaki Ishiguro, Magdalena Paolino, Verena Sigl, Toshikatsu Hanada, Reiko Hanada, Simone Lipinski, Birgit Wild, Simone M R Camargo, Dustin Singer, Andreas Richter, Keiji Kuba, Akiyoshi Fukamizu, Stefan Schreiber, Hans Clevers, Francois Verrey, Philip Rosenstiel, Josef M Penninger. ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation.
Nature.
2012 Jul; 487(7408):477-81. doi:
10.1038/nature11228. [PMID: 22837003] - Xiaojun Zhang, Franky F K Choi, Yan Zhou, Feung P Leung, Shun Tan, Shuhai Lin, Hongxi Xu, Wei Jia, Joseph J Y Sung, Zongwei Cai, Zhaoxiang Bian. Metabolite profiling of plasma and urine from rats with TNBS-induced acute colitis using UPLC-ESI-QTOF-MS-based metabonomics--a pilot study.
The FEBS journal.
2012 Jul; 279(13):2322-38. doi:
10.1111/j.1742-4658.2012.08612.x. [PMID: 22520047] - L B Teixeira, V L A A Epifânio, J J Lachat, N T Foss, J Coutinho-Netto. Oral treatment with Hev b 13 ameliorates experimental colitis in mice.
Clinical and experimental immunology.
2012 Jul; 169(1):27-32. doi:
10.1111/j.1365-2249.2012.04589.x. [PMID: 22670775] - Helieh S Oz, Jian Zhong, Willem J S de Villiers. Osteopontin ablation attenuates progression of colitis in TNBS model.
Digestive diseases and sciences.
2012 Jun; 57(6):1554-61. doi:
10.1007/s10620-011-2009-z. [PMID: 22173746] - Shi-Xue Dai, Ying Zou, Yan-Ling Feng, Hong-Bo Liu, Xue-Bao Zheng. Baicalin down-regulates the expression of macrophage migration inhibitory factor (MIF) effectively for rats with ulcerative colitis.
Phytotherapy research : PTR.
2012 Apr; 26(4):498-504. doi:
10.1002/ptr.3581. [PMID: 21887805] - Sebastian Michael, Heba Abdel-Aziz, Dieter Weiser, Christa E Müller, Olaf Kelber, Karen Nieber. Adenosine A2A receptor contributes to the anti-inflammatory effect of the fixed herbal combination STW 5 (Iberogast®) in rat small intestinal preparations.
Naunyn-Schmiedeberg's archives of pharmacology.
2012 Apr; 385(4):411-21. doi:
10.1007/s00210-011-0714-y. [PMID: 22160002] - Anna Kofla-Dlubacz, Malgorzata Matusiewicz, Malgorzata Krzystek-Korpacka, Barbara Iwanczak. Correlation of MMP-3 and MMP-9 with Crohn's disease activity in children.
Digestive diseases and sciences.
2012 Mar; 57(3):706-12. doi:
10.1007/s10620-011-1936-z. [PMID: 21997756] - Viviane Scarminio, Andrea C Fruet, Aline Witaicenis, Vera L M Rall, Luiz C Di Stasi. Dietary intervention with green dwarf banana flour (Musa sp AAA) prevents intestinal inflammation in a trinitrobenzenesulfonic acid model of rat colitis.
Nutrition research (New York, N.Y.).
2012 Mar; 32(3):202-9. doi:
10.1016/j.nutres.2012.01.002. [PMID: 22464807] - Chun-Mei Xia, Melisa A Gulick, Sharon J Yu, John R Grider, Karnam S Murthy, John F Kuemmerle, Hamid I Akbarali, Li-Ya Qiao. Up-regulation of brain-derived neurotrophic factor in primary afferent pathway regulates colon-to-bladder cross-sensitization in rat.
Journal of neuroinflammation.
2012 Feb; 9(?):30. doi:
10.1186/1742-2094-9-30. [PMID: 22335898] - Haïfa Maalmi, Anissa Berraïes, Eya Tangour, Jamel Ammar, Hanadi Abid, Kamel Hamzaoui, Agnes Hamzaoui. The impact of vitamin D deficiency on immune T cells in asthmatic children: a case-control study.
Journal of asthma and allergy.
2012; 5(?):11-9. doi:
10.2147/jaa.s29566. [PMID: 22690128] - Fei Ke, Praveen Kumar Yadav, Liu Zhan Ju. Herbal medicine in the treatment of ulcerative colitis.
Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association.
2012 Jan; 18(1):3-10. doi:
10.4103/1319-3767.91726. [PMID: 22249085] - Yaohui Zhu, Kshama Mehta, Cuiping Li, Guang-Yin Xu, Liansheng Liu, Tugba Colak, Mohan Shenoy, Pankaj Jay Pasricha. Systemic administration of anti-NGF increases A-type potassium currents and decreases pancreatic nociceptor excitability in a rat model of chronic pancreatitis.
American journal of physiology. Gastrointestinal and liver physiology.
2012 Jan; 302(1):G176-81. doi:
10.1152/ajpgi.00053.2011. [PMID: 22038828] - S Pauliina Turunen, Outi Kummu, Kirsi Harila, Marja Veneskoski, Rabah Soliymani, Marc Baumann, Pirkko J Pussinen, Sohvi Hörkkö. Recognition of Porphyromonas gingivalis gingipain epitopes by natural IgM binding to malondialdehyde modified low-density lipoprotein.
PloS one.
2012; 7(4):e34910. doi:
10.1371/journal.pone.0034910. [PMID: 22496875] - Chun-Hui Bao, Lu-Yi Wu, Yin Shi, Huan-Gan Wu, Hui-Rong Liu, Rong Zhang, Li-Qing Yu, Jin-Hai Wang. Moxibustion down-regulates colonic epithelial cell apoptosis and repairs tight junctions in rats with Crohn's disease.
World journal of gastroenterology.
2011 Dec; 17(45):4960-70. doi:
10.3748/wjg.v17.i45.4960. [PMID: 22174545] - Duanyong Liu, Xiaoying Huang, Shaomin Cheng, Wenting Tong, Panting Wan, Yongmei Guan, Haimei Zhao. [Regulation of sishen wan on Bax/Bcl-2 mRNA, Fas/FasL in colonic tissue from rats with colitis].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2011 Dec; 36(24):3484-8. doi:
". [PMID: 22368862] - Zeynep Genc, Aysen Yarat, Tugba Tunali-Akbay, Goksel Sener, Sule Cetinel, Rabia Pisiriciler, Esin Caliskan-Ak, Ayhan Altıntas, Betul Demirci. The effect of stinging nettle (Urtica dioica) seed oil on experimental colitis in rats.
Journal of medicinal food.
2011 Dec; 14(12):1554-61. doi:
10.1089/jmf.2011.0028. [PMID: 21861725] - Elena Talero, Maria Alvarez de Sotomayor, Susana Sánchez-Fidalgo, Virginia Motilva. Vascular contribution of adrenomedullin to microcirculatory improvement in experimental colitis.
European journal of pharmacology.
2011 Nov; 670(2-3):601-7. doi:
10.1016/j.ejphar.2011.09.032. [PMID: 21958875] - Chen-Mei Xia, Yuan Zhao, Li Jiang, Jie Jiang, Shun-Cai Zhang. Schistosoma japonicum ova maintains epithelial barrier function during experimental colitis.
World journal of gastroenterology.
2011 Nov; 17(43):4810-6. doi:
10.3748/wjg.v17.i43.4810. [PMID: 22147983] - Jiao He, Jinru Liang, Sha Zhu, Wenna Zhao, Yongmin Zhang, Wenji Sun. Protective effect of taurohyodeoxycholic acid from Pulvis Fellis Suis on trinitrobenzene sulfonic acid induced ulcerative colitis in mice.
European journal of pharmacology.
2011 Nov; 670(1):229-35. doi:
10.1016/j.ejphar.2011.08.036. [PMID: 21925164] - R Hanaoka, Y Ueno, S Tanaka, K Nagai, T Onitake, K Yoshioka, K Chayama. The water-soluble extract from cultured medium of Ganoderma lucidum (Reishi) mycelia (Designated as MAK) ameliorates murine colitis induced by trinitrobenzene sulphonic acid.
Scandinavian journal of immunology.
2011 Nov; 74(5):454-62. doi:
10.1111/j.1365-3083.2011.02601.x. [PMID: 21973321] - Lara Baticic, Dijana Detel, Natalia Kucic, Suncica Buljevic, Ester Pernjak Pugel, Jadranka Varljen. Neuroimmunomodulative properties of dipeptidyl peptidase IV/CD26 in a TNBS-induced model of colitis in mice.
Journal of cellular biochemistry.
2011 Nov; 112(11):3322-33. doi:
10.1002/jcb.23261. [PMID: 21751235] - Dalaal M Abdallah, Naglaa R Ismael. Resveratrol abrogates adhesion molecules and protects against TNBS-induced ulcerative colitis in rats.
Canadian journal of physiology and pharmacology.
2011 Nov; 89(11):811-8. doi:
10.1139/y11-080. [PMID: 22029500] - Soad A Yehia, Ahmed H Elshafeey, Ibrahim Elsayed. Pulsatile systems for colon targeting of budesonide: in vitro and in vivo evaluation.
Drug delivery.
2011 Nov; 18(8):620-30. doi:
10.3109/10717544.2011.621987. [PMID: 22111975] - Young-A Song, Young-Lan Park, Kyu-Yeol Kim, Cho-Yun Chung, Gi-Hoon Lee, Dae-Ho Cho, Ho-Seok Ki, Kang-Jin Park, Sung-Bum Cho, Wan-Sik Lee, Nacksung Kim, Bong-Whan Ahn, Young-Eun Joo. Black tea extract prevents lipopolysaccharide-induced NF-κB signaling and attenuates dextran sulfate sodium-induced experimental colitis.
BMC complementary and alternative medicine.
2011 Oct; 11(?):91. doi:
10.1186/1472-6882-11-91. [PMID: 21989142] - Jin Li, Rui Zhou, Wen-Cheng He, Bing Xia. Effects of recombinant human intestinal trefoil factor on trinitrobenzene sulphonic acid induced colitis in rats.
Molecular biology reports.
2011 Oct; 38(7):4787-92. doi:
10.1007/s11033-010-0616-y. [PMID: 21153768] - Yue-Meng Wan, You-Qing Zhu, Bing Xia, Jun Luo. Treating TNBS-induced colitis in rats with probiotics.
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology.
2011 Oct; 22(5):486-93. doi:
10.4318/tjg.2011.0247. [PMID: 22234755] - Marjolijn Duijvestein, Manon E Wildenberg, Mick M Welling, Simone Hennink, Ilse Molendijk, Vanessa L van Zuylen, Tjalling Bosse, Anne Christine W Vos, Eveline S M de Jonge-Muller, Helene Roelofs, Louise van der Weerd, Hein W Verspaget, Willem E Fibbe, Anje A te Velde, Gijs R van den Brink, Daniel W Hommes. Pretreatment with interferon-γ enhances the therapeutic activity of mesenchymal stromal cells in animal models of colitis.
Stem cells (Dayton, Ohio).
2011 Oct; 29(10):1549-58. doi:
10.1002/stem.698. [PMID: 21898680] - Linlin Du, Hao Tang, Zhongfu Ma, Jia Xu, Wenchao Gao, Jiajia Chen, Wenjia Gan, Zhaoping Zhang, Xinbing Yu, Xingwang Zhou, Xuchu Hu. The protective effect of the recombinant 53-kDa protein of Trichinella spiralis on experimental colitis in mice.
Digestive diseases and sciences.
2011 Oct; 56(10):2810-7. doi:
10.1007/s10620-011-1689-8. [PMID: 21476030] - Toru Kono, Yuji Omiya, Yoshiki Hira, Atsushi Kaneko, Shinichi Chiba, Tatsuya Suzuki, Masamichi Noguchi, Tsuyoshi Watanabe. Daikenchuto (TU-100) ameliorates colon microvascular dysfunction via endogenous adrenomedullin in Crohn's disease rat model.
Journal of gastroenterology.
2011 Oct; 46(10):1187-96. doi:
10.1007/s00535-011-0438-2. [PMID: 21808981] - Ingmar J J Claes, Sigrid C J De Keersmaecker, Jos Vanderleyden, Sarah Lebeer. Lessons from probiotic-host interaction studies in murine models of experimental colitis.
Molecular nutrition & food research.
2011 Oct; 55(10):1441-53. doi:
10.1002/mnfr.201100139. [PMID: 21796777] - Matthias A Engel, Andreas Leffler, Florian Niedermirtl, Alexandru Babes, Katharina Zimmermann, Miloš R Filipović, Iwona Izydorczyk, Mirjam Eberhardt, Tatjana I Kichko, Sonja M Mueller-Tribbensee, Mohammad Khalil, Norbert Siklosi, Carla Nau, Ivana Ivanović-Burmazović, Winfried L Neuhuber, Christoph Becker, Markus F Neurath, Peter W Reeh. TRPA1 and substance P mediate colitis in mice.
Gastroenterology.
2011 Oct; 141(4):1346-58. doi:
10.1053/j.gastro.2011.07.002. [PMID: 21763243] - Simone Coghetto Acedo, Erica Martins Ferreira Gotardo, Janilda Martins Lacerda, Caroline Candida de Oliveira, Patrícia de Oliveira Carvalho, Alessandra Gambero. Perinodal adipose tissue and mesenteric lymph node activation during reactivated TNBS-colitis in rats.
Digestive diseases and sciences.
2011 Sep; 56(9):2545-52. doi:
10.1007/s10620-011-1644-8. [PMID: 21380759] - O Prakash, B Medhi, U N Saikia, P Pandhi. Effect of combination of thalidomide and sulfasalazine in experimentally induced inflammatory bowel disease in rats.
Indian journal of experimental biology.
2011 Sep; 49(9):672-8. doi:
. [PMID: 21941940] - Hitoshi Setoyama, Akio Ido, Masatsugu Numata, Akihiro Moriuchi, Naohisa Yamaji, Tsutomu Tamai, Keita Funakawa, Hiroshi Fujita, Toshio Sakiyama, Hirofumi Uto, Makoto Oketani, Hirohito Tsubouchi. Repeated enemas with hepatocyte growth factor selectively stimulate epithelial cell proliferation of injured mucosa in rats with experimental colitis.
Life sciences.
2011 Aug; 89(7-8):269-75. doi:
10.1016/j.lfs.2011.06.019. [PMID: 21763320] - Yan Shen, Qiong Luo, Huimin Xu, Fangyuan Gong, Xiaobin Zhou, Yang Sun, Xuefeng Wu, Wen Liu, Guangzhi Zeng, Ninghua Tan, Qiang Xu. Mitochondria-dependent apoptosis of activated T lymphocytes induced by astin C, a plant cyclopeptide, for preventing murine experimental colitis.
Biochemical pharmacology.
2011 Aug; 82(3):260-8. doi:
10.1016/j.bcp.2011.04.013. [PMID: 21569765] - Ali Daneshmand, Hamed Mohammadi, Reza Rahimian, Peiman Habibollahi, Gohar Fakhfouri, Saman Shafat Talab, Shahram Ejtemaei Mehr, Ahmad Reza Dehpour. Chronic lithium administration ameliorates 2,4,6-trinitrobenzene sulfonic acid-induced colitis in rats; potential role for adenosine triphosphate sensitive potassium channels.
Journal of gastroenterology and hepatology.
2011 Jul; 26(7):1174-81. doi:
10.1111/j.1440-1746.2011.06719.x. [PMID: 21401719] - Yu Tang, Yonghui Liao, Nobuko Kawaguchi-Sakita, Vikram Raut, Elham Fakhrejahani, Niansong Qian, Masakazu Toi. Sinisan, a traditional Chinese medicine, attenuates experimental chronic pancreatitis induced by trinitrobenzene sulfonic acid in rats.
Journal of hepato-biliary-pancreatic sciences.
2011 Jul; 18(4):551-8. doi:
10.1007/s00534-010-0368-z. [PMID: 21234610] - In-Ah Lee, Dong-Hyun Kim. Klebsiella pneumoniae increases the risk of inflammation and colitis in a murine model of intestinal bowel disease.
Scandinavian journal of gastroenterology.
2011 Jun; 46(6):684-93. doi:
10.3109/00365521.2011.560678. [PMID: 21410316] - M Zwolinska-Wcislo, G Krzysiek-Maczka, A Ptak-Belowska, E Karczewska, R Pajdo, Z Sliwowski, K Urbanczyk, D Drozdowicz, S J Konturek, W W Pawlik, T Brzozowski. Antibiotic treatment with ampicillin accelerates the healing of colonic damage impaired by aspirin and coxib in the experimental colitis. Importance of intestinal bacteria, colonic microcirculation and proinflammatory cytokines.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.
2011 Jun; 62(3):357-68. doi:
. [PMID: 21893697] - Z Liu, X Chen, X Wang, X Chen, C-H Song, Y Du, J Su, S A Yaseen, P-C Yang. Chemokine CXCL11 links microbial stimuli to intestinal inflammation.
Clinical and experimental immunology.
2011 Jun; 164(3):396-406. doi:
10.1111/j.1365-2249.2011.04382.x. [PMID: 21438871] - S F Ghasemi-Niri, A H Abdolghaffari, S Fallah-Benakohal, M Hosseinpour-Feizi, P Mahdaviani, H Jamalifar, M Baeeri, G Dehghan, M Abdollahi. On the benefit of whey-cultured Lactobacillus casei in murine colitis.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.
2011 Jun; 62(3):341-6. doi:
". [PMID: 21893695] - Dileep G Nair, T Y Han, S Lourenssen, Michael G Blennerhassett. Proliferation modulates intestinal smooth muscle phenotype in vitro and in colitis in vivo.
American journal of physiology. Gastrointestinal and liver physiology.
2011 May; 300(5):G903-13. doi:
10.1152/ajpgi.00528.2010. [PMID: 21311027] - Marloes A A Schepens, Carolien Vink, Arjan J Schonewille, Gerard Dijkstra, Roelof van der Meer, Ingeborg M J Bovee-Oudenhoven. Dietary heme adversely affects experimental colitis in rats, despite heat-shock protein induction.
Nutrition (Burbank, Los Angeles County, Calif.).
2011 May; 27(5):590-7. doi:
10.1016/j.nut.2010.05.002. [PMID: 20705428] - D S Prasad Byrav, B Medhi, K Vaiphei, A Chakrabarti, K L Khanduja. Comparative evaluation of different doses of green tea extract alone and in combination with sulfasalazine in experimentally induced inflammatory bowel disease in rats.
Digestive diseases and sciences.
2011 May; 56(5):1369-78. doi:
10.1007/s10620-010-1446-4. [PMID: 21082353] - Pankaj Pawar, Suhit Gilda, Siddhesh Sharma, Suresh Jagtap, Anant Paradkar, Kakasaheb Mahadik, Prabhakar Ranjekar, Abhay Harsulkar. Rectal gel application of Withania somnifera root extract expounds anti-inflammatory and muco-restorative activity in TNBS-induced inflammatory bowel disease.
BMC complementary and alternative medicine.
2011 Apr; 11(?):34. doi:
10.1186/1472-6882-11-34. [PMID: 21527003] - Yin Shi, En-Hua Zhou, Huan-Gan Wu, Ci-Li Zhou, Qian-Yao Wang, Li Qi. Moxibustion treatment restoring the intestinal epithelium barrier in rats with Crohn's disease by down-regulating tumor necrosis factor alpha, tumor necrosis factor receptor 1, and tumor necrosis factor receptor 2.
Chinese journal of integrative medicine.
2011 Mar; 17(3):212-7. doi:
10.1007/s11655-011-0669-3. [PMID: 21359923] - Yan-cheng Dai, Zhi-peng Tang, Zhen-nan Wang, Ya-li Zhang, Xin-ying He. Influence of Shenqing Recipe on morphology and quantity of colonic interstitial cells of Cajal in trinitrobenzene sulfonic acid induced rat colitis.
Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih.
2011 Mar; 26(1):43-8. doi:
10.1016/s1001-9294(11)60018-7. [PMID: 21496422] - Ying Liu, Jin Xiang, Min Liu, Shi Wang, Robert J Lee, Hong Ding. Protective effects of glycyrrhizic acid by rectal treatment on a TNBS-induced rat colitis model.
The Journal of pharmacy and pharmacology.
2011 Mar; 63(3):439-46. doi:
10.1111/j.2042-7158.2010.01185.x. [PMID: 21749393] - Poonam Yadav, Nalini V Purohit. Synthesis and biological evaluation of some novel 3,4-disubstituted isocoumarins.
Indian journal of pharmaceutical sciences.
2011 Mar; 73(2):171-8. doi:
10.4103/0250-474x.91586. [PMID: 22303060] - F Isik, Tugba Tunali Akbay, A Yarat, Z Genc, R Pisiriciler, E Caliskan-Ak, S Cetinel, A Altıntas, G Sener. Protective effects of black cumin (Nigella sativa) oil on TNBS-induced experimental colitis in rats.
Digestive diseases and sciences.
2011 Mar; 56(3):721-30. doi:
10.1007/s10620-010-1333-z. [PMID: 20658190] - Xin Liu, Jianming Wang. Anti-inflammatory effects of iridoid glycosides fraction of Folium syringae leaves on TNBS-induced colitis in rats.
Journal of ethnopharmacology.
2011 Jan; 133(2):780-7. doi:
10.1016/j.jep.2010.11.010. [PMID: 21070844] - Min Zhang, Yin Long, Yang Sun, Yukun Wang, Qian Li, Huanjie Wu, Zhenjun Guo, Yuhua Li, Yinbo Niu, Chen Li, Li Liu, Qibing Mei. Evidence for the complementary and synergistic effects of the three-alkaloid combination regimen containing berberine, hypaconitine and skimmianine on the ulcerative colitis rats induced by trinitrobenzene-sulfonic acid.
European journal of pharmacology.
2011 Jan; 651(1-3):187-96. doi:
10.1016/j.ejphar.2010.10.030. [PMID: 20969848] - Margarita D Marinova, Bozhidar P Tchorbanov. Preparation of antioxidant enzymatic hydrolysates from honeybee-collected pollen using plant enzymes.
Enzyme research.
2011 Jan; 2010(?):415949. doi:
10.4061/2010/415949. [PMID: 21318132] - M Minaiyan, A R Ghannadi, M Afsharipour, P Mahzouni. Effects of extract and essential oil of Rosmarinus officinalis L. on TNBS-induced colitis in rats.
Research in pharmaceutical sciences.
2011 Jan; 6(1):13-21. doi:
. [PMID: 22049274] - Jason G Kay, Sergio Grinstein. Sensing phosphatidylserine in cellular membranes.
Sensors (Basel, Switzerland).
2011; 11(2):1744-55. doi:
10.3390/s110201744. [PMID: 22319379] - Sílvia Helena Cestari, Jairo Kennup Bastos, Luiz Claudio Di Stasi. Intestinal Anti-Inflammatory Activity of Baccharis dracunculifolia in the Trinitrobenzenesulphonic Acid Model of Rat Colitis.
Evidence-based complementary and alternative medicine : eCAM.
2011; 2011(?):524349. doi:
10.1093/ecam/nep081. [PMID: 19592480] - Amna Al-Shamali, Islam Khan. Expression of Na-H exchanger-8 isoform is suppressed in experimental colitis in adult rat: lack of reversibility by dexamethasone.
Scandinavian journal of gastroenterology.
2011 Jan; 46(1):20-9. doi:
10.3109/00365521.2010.521890. [PMID: 20950207] - Ken Inoue, Yuji Naito, Tomohisa Takagi, Natsuko Hayashi, Yasuko Hirai, Katsura Mizushima, Ryusuke Horie, Kohei Fukumoto, Shinya Yamada, Akihito Harusato, Ikuhiro Hirata, Tatsushi Omatsu, Naohisa Yoshida, Kazuhiko Uchiyama, Takeshi Ishikawa, Osamu Handa, Hideyuki Konishi, Naoki Wakabayashi, Nobuaki Yagi, Hiroshi Ichikawa, Satoshi Kokura, Toshikazu Yoshikawa. Daikenchuto, a Kampo medicine, regulates intestinal fibrosis associated with decreasing expression of heat shock protein 47 and collagen content in a rat colitis model.
Biological & pharmaceutical bulletin.
2011; 34(11):1659-65. doi:
10.1248/bpb.34.1659. [PMID: 22040876] - Z K Coskun, M Kerem, N Gurbuz, S Omeroglu, H Pasaoglu, C Demirtas, N Lortlar, B Salman, O T Pasaoglu, H B Turgut. The study of biochemical and histopathological effects of spirulina in rats with TNBS-induced colitis.
Bratislavske lekarske listy.
2011; 112(5):235-43. doi:
". [PMID: 21682075] - Reza Rahimian, Gohar Fakhfouri, Ali Daneshmand, Hamed Mohammadi, Arash Bahremand, Mohammad Reza Rasouli, Kazem Mousavizadeh, Ahmad Reza Dehpour. Adenosine A2A receptors and uric acid mediate protective effects of inosine against TNBS-induced colitis in rats.
European journal of pharmacology.
2010 Dec; 649(1-3):376-81. doi:
10.1016/j.ejphar.2010.09.044. [PMID: 20868668] - In-Ah Lee, Yang-Jin Hyun, Dong-Hyun Kim. Berberine ameliorates TNBS-induced colitis by inhibiting lipid peroxidation, enterobacterial growth and NF-κB activation.
European journal of pharmacology.
2010 Dec; 648(1-3):162-70. doi:
10.1016/j.ejphar.2010.08.046. [PMID: 20828550] - Laurent Ferrier, Claudine Serradeil-Le Gal, Anke M Schulte, Valentina Vasina, Eric Gaultier, Silke Schroedel, Maria Grazia Ursino, Gilles Chaumaz, Marc Pascal, Fabrizio De Ponti, Lionel Bueno. Proinflammatory role of vasopressin through V1b receptors in hapten-induced experimental colitis in rodents: implication in IBD.
American journal of physiology. Gastrointestinal and liver physiology.
2010 Dec; 299(6):G1298-307. doi:
10.1152/ajpgi.00022.2010. [PMID: 20864658] - Frances Puleo, Katia Meirelles, Maithili Navaratnarajah, Leo Fitzpatrick, Margaret L Shumate, Robert N Cooney, Charles H Lang. Skeletal muscle catabolism in trinitrobenzene sulfonic acid-induced murine colitis.
Metabolism: clinical and experimental.
2010 Nov; 59(11):1680-90. doi:
10.1016/j.metabol.2010.03.021. [PMID: 20546811] - Hiroshi Kono, Hideki Fujii, Masahito Ogiku, Masato Tsuchiya, Kenichi Ishii, Michio Hara. Enteral diets enriched with medium-chain triglycerides and N-3 fatty acids prevent chemically induced experimental colitis in rats.
Translational research : the journal of laboratory and clinical medicine.
2010 Nov; 156(5):282-91. doi:
10.1016/j.trsl.2010.07.012. [PMID: 20970751] - Hannah Schneider, Annika Braun, Joachim Füllekrug, Wolfgang Stremmel, Robert Ehehalt. Lipid based therapy for ulcerative colitis-modulation of intestinal mucus membrane phospholipids as a tool to influence inflammation.
International journal of molecular sciences.
2010 Oct; 11(10):4149-64. doi:
10.3390/ijms11104149. [PMID: 21152327] - Yi Liao, Heng Fan, Xiao-Yan Chen. [Pathogenetic mechanism of beta-arrestin1 in experimental colitis of rats and intervention effects of oxymatrine].
Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.
2010 Oct; 30(10):1067-72. doi:
". [PMID: 21066892] - Tomohisa Takagi, Yuji Naito, Katsura Mizushima, Satomi Akagiri, Takahiro Suzuki, Ikuhiro Hirata, Tatsushi Omatsu, Osamu Handa, Satoshi Kokura, Hiroshi Ichikawa, Toshikazu Yoshikawa. Inhalation of carbon monoxide ameliorates TNBS-induced colitis in mice through the inhibition of TNF-α expression.
Digestive diseases and sciences.
2010 Oct; 55(10):2797-804. doi:
10.1007/s10620-009-1112-x. [PMID: 20094779] - Nathália Nahas Grijó, Ricardo Carneiro Borra, Vera Lucia Sdepanian. Proinflammatory and anti-inflammatory cytokines present in the acute phase of experimental colitis treated with Saccharomyces boulardii.
Digestive diseases and sciences.
2010 Sep; 55(9):2498-504. doi:
10.1007/s10620-009-1072-1. [PMID: 19997974] - Onseok Lee, Myeunghun Choi, Seunghan Ha, Gunwoo Lee, Jaeyoung Kim, Gyuman Park, Minwon Lee, Youngwook Choi, Mingi Kim, Chil Hwan Oh. Effect of pedunculagin investigated by non-invasive evaluation on atopic-like dermatitis in NC/Nga mice.
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI).
2010 Aug; 16(3):371-7. doi:
10.1111/j.1600-0846.2010.00443.x. [PMID: 20637007] - Amir Baghaei, Hadi Esmaily, Amir Hossein Abdolghaffari, Maryam Baeeri, Farhad Gharibdoost, Mohammad Abdollahi. Efficacy of Setarud (IMod), a novel drug with potent anti-toxic stress potential in rat inflammatory bowel disease and comparison with dexamethasone and infliximab.
Indian journal of biochemistry & biophysics.
2010 Aug; 47(4):219-26. doi:
". [PMID: 21174949] - Jung Mogg Kim, Hyoun Woo Kang, Mi Yeon Cha, Doyoung Yoo, Nayoung Kim, In-Kyoung Kim, Jeounghun Ku, Sunil Kim, Sang-Ho Ma, Hyun Chae Jung, In Sung Song, Joo Sung Kim. Novel guggulsterone derivative GG-52 inhibits NF-kappaB signaling in intestinal epithelial cells and attenuates acute murine colitis.
Laboratory investigation; a journal of technical methods and pathology.
2010 Jul; 90(7):1004-15. doi:
10.1038/labinvest.2010.54. [PMID: 20195240] - Toru Kono, Atsushi Kaneko, Yoshiki Hira, Tatsuya Suzuki, Naoyuki Chisato, Nobuhiro Ohtake, Naoko Miura, Tsuyoshi Watanabe. Anti-colitis and -adhesion effects of daikenchuto via endogenous adrenomedullin enhancement in Crohn's disease mouse model.
Journal of Crohn's & colitis.
2010 Jun; 4(2):161-70. doi:
10.1016/j.crohns.2009.09.006. [PMID: 21122500] - Yue-meng Wan, You-qing Zhu, Bing Xia, Jun Luo. [Probiotic therapy using live combined bifidobacterium, lactobacillus and enterococcus for experimental colitis in rats model].
Zhonghua nei ke za zhi.
2010 May; 49(5):418-21. doi:
. [PMID: 20646418] - In-Ah Lee, Eun-Ah Bae, Jung-Hee Lee, Hoyong Lee, Young-Tae Ahn, Chul-Sung Huh, Dong-Hyun Kim. Bifidobacterium longum HY8004 attenuates TNBS-induced colitis by inhibiting lipid peroxidation in mice.
Inflammation research : official journal of the European Histamine Research Society ... [et al.].
2010 May; 59(5):359-68. doi:
10.1007/s00011-009-0108-5. [PMID: 19882302] - Eun-Ha Joh, In-Ah Lee, Sang-Jun Han, Sunju Chae, Dong-Hyun Kim. Lancemaside A ameliorates colitis by inhibiting NF-kappaB activation in TNBS-induced colitis mice.
International journal of colorectal disease.
2010 May; 25(5):545-51. doi:
10.1007/s00384-009-0858-0. [PMID: 19956958] - Brad A Pasternak, Sharon D'Mello, Ingrid I Jurickova, Xiaonan Han, Tara Willson, Leah Flick, Lisa Petiniot, Naonori Uozumi, Senad Divanovic, Anna Traurnicht, Erin Bonkowski, Subra Kugathasan, Christopher L Karp, Lee A Denson. Lipopolysaccharide exposure is linked to activation of the acute phase response and growth failure in pediatric Crohn's disease and murine colitis.
Inflammatory bowel diseases.
2010 May; 16(5):856-69. doi:
10.1002/ibd.21132. [PMID: 19924809] - Amir Hossein Abdolghaffari, Amir Baghaei, Fariborz Moayer, Hadi Esmaily, Maryam Baeeri, Hamid Reza Monsef-Esfahani, Reza Hajiaghaee, Mohammad Abdollahi. On the benefit of Teucrium in murine colitis through improvement of toxic inflammatory mediators.
Human & experimental toxicology.
2010 Apr; 29(4):287-95. doi:
10.1177/0960327110361754. [PMID: 20144954] - Robert D Thurston, Claire B Larmonier, Pawel M Majewski, Rajalakshmy Ramalingam, Monica Midura-Kiela, Daniel Laubitz, Alain Vandewalle, David G Besselsen, Marcus Mühlbauer, Christian Jobin, Pawel R Kiela, Fayez K Ghishan. Tumor necrosis factor and interferon-gamma down-regulate Klotho in mice with colitis.
Gastroenterology.
2010 Apr; 138(4):1384-94, 1394.e1. doi:
10.1053/j.gastro.2009.12.002. [PMID: 20004202] - Maria Silene da Silva, Susana Sánchez-Fidalgo, Elena Talero, Ana Cárdeno, Marcelo Aparecido da Silva, Wagner Villegas, Alba Regina Monteiro Souza Brito, Catalina Alarcón de La Lastra. Anti-inflammatory intestinal activity of Abarema cochliacarpos (Gomes) Barneby & Grimes in TNBS colitis model.
Journal of ethnopharmacology.
2010 Mar; 128(2):467-75. doi:
10.1016/j.jep.2010.01.024. [PMID: 20083187] - Bheki A Xulu, Michael T Ashby. Small molecular, macromolecular, and cellular chloramines react with thiocyanate to give the human defense factor hypothiocyanite.
Biochemistry.
2010 Mar; 49(9):2068-74. doi:
10.1021/bi902089w. [PMID: 20085320] - Eunyoung Ha, Ji-Hye Bang, Jung N Son, Ho-Chan Cho, Kyo-Chul Mun. Carbamylated albumin stimulates microRNA-146, which is increased in human renal cell carcinoma.
Molecular medicine reports.
2010 Mar; 3(2):275-9. doi:
10.3892/mmr_00000251. [PMID: 21472233] - G Varga, D Erces, B Fazekas, M Fülöp, T Kovács, J Kaszaki, F Fülöp, L Vécsei, M Boros. N-Methyl-D-aspartate receptor antagonism decreases motility and inflammatory activation in the early phase of acute experimental colitis in the rat.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.
2010 Feb; 22(2):217-25, e68. doi:
10.1111/j.1365-2982.2009.01390.x. [PMID: 19735360] - Hu Wei-Guo, Liao Xi-Wang, Lu Qi-Ping. Expression of sonic hedgehog signaling pathways in a rat model of chronic pancreatitis.
Saudi medical journal.
2010 Jan; 31(1):14-7. doi:
NULL. [PMID: 20062892] - Fiore Cattaruzza, Ian Spreadbury, Marcela Miranda-Morales, Eileen F Grady, Stephen Vanner, Nigel W Bunnett. Transient receptor potential ankyrin-1 has a major role in mediating visceral pain in mice.
American journal of physiology. Gastrointestinal and liver physiology.
2010 Jan; 298(1):G81-91. doi:
10.1152/ajpgi.00221.2009. [PMID: 19875705] - Yuji Naito, Tomohisa Takagi, Toshikazu Yoshikawa. Gastrointestinal Cytoprotection by PPARγ Ligands.
PPAR research.
2010; 2010(?):. doi:
10.1155/2010/108632. [PMID: 20885923] - Siyuan Zhou, Bangle Zhang, Xinyou Liu, Zenghui Teng, Menglei Huan, Tiehong Yang, Zhifu Yang, Min Jia, Qibing Mei. A new natural angelica polysaccharide based colon-specific drug delivery system.
Journal of pharmaceutical sciences.
2009 Dec; 98(12):4756-68. doi:
10.1002/jps.21790. [PMID: 19408300] - Li Liu, Shifang Yuan, Yin Long, Zhenjun Guo, Yang Sun, Yuhua Li, Yinbo Niu, Chen Li, Qibing Mei. Immunomodulation of Rheum tanguticum polysaccharide (RTP) on the immunosuppressive effects of dexamethasone (DEX) on the treatment of colitis in rats induced by 2,4,6-trinitrobenzene sulfonic acid.
International immunopharmacology.
2009 Dec; 9(13-14):1568-77. doi:
10.1016/j.intimp.2009.09.013. [PMID: 19788936] - Ji Yun Lee, Hyo Sook Kang, Byoung Eon Park, Hyo Jin Moon, Sang Soo Sim, Chang Jong Kim. Inhibitory effects of Geijigajakyak-Tang on trinitrobenzene sulfonic acid-induced colitis.
Journal of ethnopharmacology.
2009 Nov; 126(2):244-51. doi:
10.1016/j.jep.2009.08.035. [PMID: 19716872] - Andrea Mencarelli, Barbara Renga, Giuseppe Palladino, Eleonora Distrutti, Stefano Fiorucci. The plant sterol guggulsterone attenuates inflammation and immune dysfunction in murine models of inflammatory bowel disease.
Biochemical pharmacology.
2009 Nov; 78(9):1214-23. doi:
10.1016/j.bcp.2009.06.026. [PMID: 19555671]