3,4,5-Trichloropyridin-2-ol (BioDeep_00000174050)
human metabolite blood metabolite
代谢物信息卡片
化学式: C5H2Cl3NO (196.9201972)
中文名称: 3,4,5-三氯-2(1H)-吡啶酮
谱图信息:
最多检出来源 Homo sapiens(blood) 75%
分子结构信息
SMILES: C1=C(C(=C(C(=O)N1)Cl)Cl)Cl
InChI: InChI=1S/C5H2Cl3NO/c6-2-1-9-5(10)4(8)3(2)7/h1H,(H,9,10)
描述信息
同义名列表
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Fayssal M Farahat, Corie A Ellison, Matthew R Bonner, Barbara P McGarrigle, Alice L Crane, Richard A Fenske, Michael R Lasarev, Diane S Rohlman, W Kent Anger, Pamela J Lein, James R Olson. Biomarkers of chlorpyrifos exposure and effect in Egyptian cotton field workers.
Environmental health perspectives.
2011 Jun; 119(6):801-6. doi:
10.1289/ehp.1002873. [PMID: 21224175] - Kian Loong Lim, Annie Tay, Vishna Devi Nadarajah, Nilesh Kumar Mitra. The effect of consequent exposure of stress and dermal application of low doses of chlorpyrifos on the expression of glial fibrillary acidic protein in the hippocampus of adult mice.
Journal of occupational medicine and toxicology (London, England).
2011 Mar; 6(1):4. doi:
10.1186/1745-6673-6-4. [PMID: 21385392] - Limin Wang, Donglai Lu, Jun Wang, Dan Du, Zhexiang Zou, Hua Wang, Jordan N Smith, Charles Timchalk, Fengquan Liu, Yuehe Lin. A novel immunochromatographic electrochemical biosensor for highly sensitive and selective detection of trichloropyridinol, a biomarker of exposure to chlorpyrifos.
Biosensors & bioelectronics.
2011 Feb; 26(6):2835-40. doi:
10.1016/j.bios.2010.11.008. [PMID: 21195597] - L Caporossi, A Santoro, G Tranfo, B Papaleo. [Salivary analyses for biologic monitoring: possibility and perspectives].
Giornale italiano di medicina del lavoro ed ergonomia.
2007 Jul; 29(3 Suppl):532-4. doi:
. [PMID: 18409816] - Ryan L Williams, Linda S Aston, Robert I Krieger. Perspiration increased human pesticide absorption following surface contact during an indoor scripted activity program.
Journal of exposure analysis and environmental epidemiology.
2004 Mar; 14(2):129-36. doi:
10.1038/sj.jea.7500301. [PMID: 15014543] - P A Smith, M J Thompson, J W Edwards. Estimating occupational exposure to the pyrethroid termiticide bifenthrin by measuring metabolites in urine.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2002 Oct; 778(1-2):113-20. doi:
10.1016/s0378-4347(01)00440-6. [PMID: 12376119] - Tapas K Sar, Biplab Bagchi, Shyamal K Das, Tapan K Mandal, Animesh K Chakraborty, Anjan Bhattacharyya, Ashim Choudhury. Toxicokinetics, recovery, and metabolism of triclopyr butotyl (ACTP) ester in goats.
Journal of agricultural and food chemistry.
2002 Jul; 50(15):4202-9. doi:
10.1021/jf011350n. [PMID: 12105946] - D Qiao, F J Seidler, T A Slotkin. Developmental neurotoxicity of chlorpyrifos modeled in vitro: comparative effects of metabolites and other cholinesterase inhibitors on DNA synthesis in PC12 and C6 cells.
Environmental health perspectives.
2001 Sep; 109(9):909-13. doi:
10.1289/ehp.01109909. [PMID: 11673119]