3,3',5,5'-Tetrachlorobiphenyl (BioDeep_00000174027)

   

human metabolite blood metabolite Industrial Pollutants


代谢物信息卡片


1,3-dichloro-5-(3,5-dichlorophenyl)benzene

化学式: C12H6Cl4 (289.92235960000005)
中文名称: 3,3,5,5-四氯联苯
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=C(C=C(C=C1Cl)Cl)C2=CC(=CC(=C2)Cl)Cl
InChI: InChI=1S/C12H6Cl4/c13-9-1-7(2-10(14)5-9)8-3-11(15)6-12(16)4-8/h1-6H

描述信息

D004785 - Environmental Pollutants > D011078 - Polychlorinated Biphenyls

同义名列表

5 个代谢物同义名

1,3-dichloro-5-(3,5-dichlorophenyl)benzene; 1,1-Biphenyl,3,3,5,5-tetrachloro-; 3,3,5,5-Tetrachlorobiphenyl; 3,3,5,5-Tetrachlorodiphenyl; 3,5,3,5-Tetrachlorobiphenyl



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

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1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Margaret R Bell, Ariel Dryden, Ryan Will, Andrea C Gore. Sex differences in effects of gestational polychlorinated biphenyl exposure on hypothalamic neuroimmune and neuromodulator systems in neonatal rats. Toxicology and applied pharmacology. 2018 08; 353(?):55-66. doi: 10.1016/j.taap.2018.06.002. [PMID: 29879404]
  • Gregory D Lyng, Abigail Snyder-Keller, Richard F Seegal. Polychlorinated biphenyl-induced neurotoxicity in organotypic cocultures of developing rat ventral mesencephalon and striatum. Toxicological sciences : an official journal of the Society of Toxicology. 2007 May; 97(1):128-39. doi: 10.1093/toxsci/kfm027. [PMID: 17324953]
  • Mercedes Fernández Santiago, Pilar López-Aparicio, María N Recio, Miguel A Pérez-Albarsanz. Effect of aroclor 1248 and two pure PCB congeners on phospholipase D activity in rat renal tubular cell cultures. Journal of biochemical and molecular toxicology. 2007; 21(2):68-75. doi: 10.1002/jbt.20160. [PMID: 17427178]
  • Gail F Jurgella, Ashok Marwah, Jeffrey A Malison, Richard Peterson, Terence P Barry. Effects of xenobiotics and steroids on renal and hepatic estrogen metabolism in lake trout. General and comparative endocrinology. 2006 Sep; 148(2):273-81. doi: 10.1016/j.ygcen.2006.03.011. [PMID: 16677648]
  • Mercedes Fernández Santiago, Pedro L Pérez-Reyes, Pilar López-Aparicio, María N Recio, Miguel A Pérez-Albarsanz. Differential effects of PCBs on the induction of apoptosis machinery and PKCalpha translocation in rat renal tubular cell cultures. Toxicology letters. 2006 May; 163(2):91-100. doi: 10.1016/j.toxlet.2005.09.032. [PMID: 16263226]
  • Hans E Purkey, Satheesh K Palaninathan, Kathleen C Kent, Craig Smith, Stephen H Safe, James C Sacchettini, Jeffery W Kelly. Hydroxylated polychlorinated biphenyls selectively bind transthyretin in blood and inhibit amyloidogenesis: rationalizing rodent PCB toxicity. Chemistry & biology. 2004 Dec; 11(12):1719-28. doi: 10.1016/j.chembiol.2004.10.009. [PMID: 15610856]
  • P J Korytko, A C Casey, B Bush, F W Quimby. Induction of hepatic cytochromes P450 in dogs exposed to a chronic low dose of polychlorinated biphenyls. Toxicological sciences : an official journal of the Society of Toxicology. 1999 Jan; 47(1):52-61. doi: 10.1093/toxsci/47.1.52. [PMID: 10048153]
  • N Koga, N Nishimura, H Kuroki, Y Masuda, H Yoshimura. Metabolism of 3,5,3',5'-tetrachlorobiphenyl by rat liver microsomes and purified P4501A1. Xenobiotica; the fate of foreign compounds in biological systems. 1994 Aug; 24(8):775-83. doi: 10.3109/00498259409043277. [PMID: 7839700]
  • L Tryphonas, J Truelove, Z Zawidzka, J Wong, J Mes, S Charbonneau, D L Grant, J S Campbell. Polychlorinated biphenyl (PCB) toxicity in adult cynomolgus monkeys (M. fascicularis): a pilot study. Toxicologic pathology. 1984; 12(1):10-25. doi: 10.1177/019262338401200103. [PMID: 6436955]