3-Methyl-4-nitrophenol (BioDeep_00000173954)
human metabolite blood metabolite
代谢物信息卡片
4-Nitro-3-cresol, sodium salt
化学式: C7H7NO3 (153.0425912)
中文名称: 4-硝基间甲酚
谱图信息:
最多检出来源 Homo sapiens(blood) 19.86%
分子结构信息
SMILES: CC1=C(C=CC(=C1)O)[N+](=O)[O-]
InChI: InChI=1S/C7H7NO3/c1-5-4-6(9)2-3-7(5)8(10)11/h2-4,9H,1H3
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
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Talanta.
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Bioelectrochemistry (Amsterdam, Netherlands).
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10.1016/j.bioelechem.2019.01.001. [PMID: 30703737] - Lubing Yang, Sihui Ma, Yu Han, Yuhan Wang, Yan Guo, Qiang Weng, Meiyu Xu. Walnut Polyphenol Extract Attenuates Immunotoxicity Induced by 4-Pentylphenol and 3-methyl-4-nitrophenol in Murine Splenic Lymphocyte.
Nutrients.
2016 May; 8(5):. doi:
10.3390/nu8050287. [PMID: 27187455] - Kateryna Babina, Maureen Dollard, Louis Pilotto, John W Edwards. Environmental exposure to organophosphorus and pyrethroid pesticides in South Australian preschool children: a cross sectional study.
Environment international.
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10.1016/j.envint.2012.07.007. [PMID: 22892382] - Zhuo Yue, Rui-Ping She, Hui-Hui Bao, Jijing Tian, Pin Yu, Jinfeng Zhu, Lingling Chang, Ye Ding, Quan Sun. Necrosis and apoptosis of renal tubular epithelial cells in rats exposed to 3-methyl-4-nitrophenol.
Environmental toxicology.
2012 Nov; 27(11):653-61. doi:
10.1002/tox.20688. [PMID: 21374789] - Ai Okamura, Isao Saito, Jun Ueyama, Yuki Ito, Tamie Nakajima, Michihiro Kamijima. New analytical method for sensitive quantification of urinary 3-methyl-4-nitrophenol to assess fenitrothion exposure in general population and occupational sprayers.
Toxicology letters.
2012 Apr; 210(2):220-4. doi:
10.1016/j.toxlet.2011.10.008. [PMID: 22027349] - Tong-liang Bu, Yu-dong Jia, Jin-xing Lin, Yu-ling Mi, Cai-qiao Zhang. Alleviative effect of quercetin on germ cells intoxicated by 3-methyl-4-nitrophenol from diesel exhaust particles.
Journal of Zhejiang University. Science. B.
2012 Apr; 13(4):318-26. doi:
10.1631/jzus.b1100318. [PMID: 22467373] - Toshiaki Yoshida, Jin Yoshida. Simultaneous analytical method for urinary metabolites of organophosphorus compounds and moth repellents in general population.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2012 Jan; 880(1):66-73. doi:
10.1016/j.jchromb.2011.11.018. [PMID: 22130501] - Zhuo Yue, Ruiping She, Huihui Bao, Wengui Li, Decheng Wang, Jinfeng Zhu, Lingling Chang, Pin Yu. Exposure to 3-methyl-4-nitrophenol affects testicular morphology and induces spermatogenic cell apoptosis in immature male rats.
Research in veterinary science.
2011 Oct; 91(2):261-8. doi:
10.1016/j.rvsc.2010.12.009. [PMID: 21440924] - Eliseo Herrero-Hernández, Rita Carabias-Martínez, Encarnacion Rodríguez-Gonzalo. Behavior of phenols and phenoxyacids on a bisphenol-A imprinted polymer. Application for selective solid-phase extraction from water and urine samples.
International journal of molecular sciences.
2011; 12(5):3322-39. doi:
10.3390/ijms12053322. [PMID: 21686187] - Yuling Mi, Caiqiao Zhang, ChunMei Li, Shinji Taneda, Gen Watanabe, Akira K Suzuki, Kazuyoshi Taya. Quercetin protects embryonic chicken spermatogonial cells from oxidative damage intoxicated with 3-methyl-4-nitrophenol in primary culture.
Toxicology letters.
2009 Oct; 190(1):61-5. doi:
10.1016/j.toxlet.2009.07.002. [PMID: 19596427] - Xuezheng Li, ChunMei Li, Akira K Suzuki, Gen Watanabe, Shinji Taneda, Kazuyoshi Taya. Endocrine disruptive effect of 3-methyl-4-nitrophenol isolated from diesel exhaust particles in Hershberger assay using castrated immature rats.
Bioscience, biotechnology, and biochemistry.
2009 Sep; 73(9):2018-21. doi:
10.1271/bbb.90204. [PMID: 19734673] - ChunMei Li, Akira K Suzuki, Shinji Takahashi, Shinji Taneda, Gen Watanabe, Kazuyoshi Taya. Effects of 3-methyl-4-nitrophenol on the reproductive toxicity in female Japanese quail (Coturnix japonica).
Biological & pharmaceutical bulletin.
2008 Nov; 31(11):2158-61. doi:
10.1248/bpb.31.2158. [PMID: 18981592] - S M A D Zayed, F Mahdy. Decomposition of 14C-fenitrothion under the influence of UV and sunlight under tropical and subtropical conditions.
Chemosphere.
2008 Feb; 70(9):1653-9. doi:
10.1016/j.chemosphere.2007.07.063. [PMID: 17822740] - Alicia Sánchez, Silvia Millán, M Carmen Sampedro, Nora Unceta, Esther Rodríguez, M Aranzazu Goicolea, Ramón J Barrio. Quantification of fenitrothion and its main metabolites in poplar leaves by isotope dilution gas chromatography-mass spectrometry coupled with solid-phase microextraction.
Journal of chromatography. A.
2008 Jan; 1177(1):170-4. doi:
10.1016/j.chroma.2007.10.097. [PMID: 18048045] - Chunmei Li, Shinji Taneda, Akira K Suzuki, Chie Furuta, Gen Watanabe, Kazuyoshi Taya. Effects of 3-methyl-4-nitrophenol on the suppression of adrenocortical function in immature male rats.
Biological & pharmaceutical bulletin.
2007 Dec; 30(12):2376-80. doi:
10.1248/bpb.30.2376. [PMID: 18057729] - J Van Durme, J Dewulf, W Sysmans, C Leys, H Van Langenhove. Abatement and degradation pathways of toluene in indoor air by positive corona discharge.
Chemosphere.
2007 Aug; 68(10):1821-9. doi:
10.1016/j.chemosphere.2007.03.053. [PMID: 17490711] - ChunMei Li, Shinji Takahashi, Shinji Taneda, Chie Furuta, Gen Watanabe, Akira K Suzuki, Kazuyoshi Taya. Effects of 3-methyl-4-nitrophenol in diesel exhaust particles on the regulation of reproductive function in immature female Japanese quail (Coturnix japonica).
The Journal of reproduction and development.
2007 Jun; 53(3):673-8. doi:
10.1262/jrd.18133. [PMID: 17202750] - Chunmei Li, Shinji Taneda, Akira K Suzuki, Chie Furuta, Gen Watanabe, Kazuyoshi Taya. Effects of 3-methyl-4-nitrophenol in diesel exhaust particles on the regulation of testicular function in immature male rats.
Journal of andrology.
2007 Mar; 28(2):252-8. doi:
10.2164/jandrol.106.000802. [PMID: 17021341] - Jibin Sun, Xin Lu, Ursula Rinas, An Ping Zeng. Metabolic peculiarities of Aspergillus niger disclosed by comparative metabolic genomics.
Genome biology.
2007; 8(9):R182. doi:
10.1186/gb-2007-8-9-r182. [PMID: 17784953] - ChunMei Li, Shinji Taneda, Akira K Suzuki, Chie Furuta, Gen Watanabe, Kazuyoshi Taya. Anti-androgenic activity of 3-methyl-4-nitrophenol in diesel exhaust particles.
European journal of pharmacology.
2006 Aug; 543(1-3):194-9. doi:
10.1016/j.ejphar.2006.06.010. [PMID: 16822498] - ChunMei Li, Shinji Takahashi, Shinji Taneda, Chie Furuta, Gen Watanabe, Akira K Suzuki, Kazuyoshi Taya. Impairment of testicular function in adult male Japanese quail (Coturnix japonica) after a single administration of 3-methyl-4-nitrophenol in diesel exhaust particles.
The Journal of endocrinology.
2006 Jun; 189(3):555-64. doi:
10.1677/joe.1.06628. [PMID: 16731786] - F Hernández, J V Sancho, O J Pozo. An estimation of the exposure to organophosphorus pesticides through the simultaneous determination of their main metabolites in urine by liquid chromatography-tandem mass spectrometry.
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2004 Sep; 808(2):229-39. doi:
10.1016/j.jchromb.2004.05.019. [PMID: 15261816] - Masao Fukushima, Takuo Fujisawa, Toshiyuki Katagi, Yoshiyuki Takimoto. Metabolism of fenitrothion and conjugation of 3-methyl-4-nitrophenol in tomato plant (Lycopersicon esculentum).
Journal of agricultural and food chemistry.
2003 Aug; 51(17):5016-23. doi:
10.1021/jf034289q. [PMID: 12903963] - Juan V Sancho, Oscar J Pozo, Francisco J López, Félix Hernández. Different quantitation approaches for xenobiotics in human urine samples by liquid chromatography/electrospray tandem mass spectrometry.
Rapid communications in mass spectrometry : RCM.
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