3-Iodothyroacetic acid (BioDeep_00000173939)
human metabolite blood metabolite
代谢物信息卡片
化学式: C14H11IO4 (369.97020760000004)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 66.67%
分子结构信息
SMILES: C1=CC(=CC=C1O)OC2=C(C=C(C=C2)CC(=O)O)I
InChI: InChI=1S/C14H11IO4/c15-12-7-9(8-14(17)18)1-6-13(12)19-11-4-2-10(16)3-5-11/h1-7,16H,8H2,(H,17,18)
描述信息
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
同义名列表
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Josef Köhrle, Heike Biebermann. 3-Iodothyronamine-A Thyroid Hormone Metabolite With Distinct Target Profiles and Mode of Action.
Endocrine reviews.
2019 04; 40(2):602-630. doi:
10.1210/er.2018-00182
. [PMID: 30649231] - Leonardo Lorenzini, Sandra Ghelardoni, Alessandro Saba, Ginevra Sacripanti, Grazia Chiellini, Riccardo Zucchi. Recovery of 3-Iodothyronamine and Derivatives in Biological Matrixes: Problems and Pitfalls.
Thyroid : official journal of the American Thyroid Association.
2017 10; 27(10):1323-1331. doi:
10.1089/thy.2017.0111
. [PMID: 28859548] - Carolin S Hoefig, Simon F Jacobi, Amy Warner, Lisbeth Harder, Nancy Schanze, Björn Vennström, Jens Mittag. 3-Iodothyroacetic acid lacks thermoregulatory and cardiovascular effects in vivo.
British journal of pharmacology.
2015 Jul; 172(13):3426-33. doi:
10.1111/bph.13131
. [PMID: 25765843] - Claudia Musilli, Gaetano De Siena, Maria Elena Manni, Andrea Logli, Elisa Landucci, Riccardo Zucchi, Alessandro Saba, Riccardo Donzelli, Maria Beatrice Passani, Gustavo Provensi, Laura Raimondi. Histamine mediates behavioural and metabolic effects of 3-iodothyroacetic acid, an endogenous end product of thyroid hormone metabolism.
British journal of pharmacology.
2014 Jul; 171(14):3476-84. doi:
10.1111/bph.12697
. [PMID: 24641572] - Sarah A Hackenmueller, Thomas S Scanlan. Identification and quantification of 3-iodothyronamine metabolites in mouse serum using liquid chromatography-tandem mass spectrometry.
Journal of chromatography. A.
2012 Sep; 1256(?):89-97. doi:
10.1016/j.chroma.2012.07.052
. [PMID: 22885046] - Alessandro Saba, Grazia Chiellini, Sabina Frascarelli, Maja Marchini, Sandra Ghelardoni, Andrea Raffaelli, Massimo Tonacchera, Paolo Vitti, Thomas S Scanlan, Riccardo Zucchi. Tissue distribution and cardiac metabolism of 3-iodothyronamine.
Endocrinology.
2010 Oct; 151(10):5063-73. doi:
10.1210/en.2010-0491
. [PMID: 20739399] - Warren J L Wood, Travis Geraci, Aaron Nilsen, Andrea E DeBarber, Thomas S Scanlan. Iodothyronamines are oxidatively deaminated to iodothyroacetic acids in vivo.
Chembiochem : a European journal of chemical biology.
2009 Jan; 10(2):361-5. doi:
10.1002/cbic.200800607
. [PMID: 19105176]