3-Hydroxycyclobut-2-en-1-one (BioDeep_00000173927)

   

human metabolite blood metabolite


代谢物信息卡片


3-Hydroxycyclobut-2-en-1-one

化学式: C4H4O2 (84.0211284)
中文名称:
谱图信息: 最多检出来源 Mus musculus(blood) 66.67%

分子结构信息

SMILES: C1C(=CC1=O)O
InChI: InChI=1S/C4H4O2/c5-3-1-4(6)2-3/h1,5H,2H2

描述信息

同义名列表

2 个代谢物同义名

3-Hydroxycyclobut-2-en-1-one; Squaraine



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Takeshi Fukuda, Shinya Yokomizo, Stefanie Casa, Hailey Monaco, Sophia Manganiello, Haoran Wang, Xiangmin Lv, Amy Daniel Ulumben, Chengeng Yang, Min-Woong Kang, Kazumasa Inoue, Masahiro Fukushi, Toshiyuki Sumi, Cheng Wang, Homan Kang, Kai Bao, Maged Henary, Satoshi Kashiwagi, Hak Soo Choi. Fast and Durable Intraoperative Near-infrared Imaging of Ovarian Cancer Using Ultrabright Squaraine Fluorophores. Angewandte Chemie (International ed. in English). 2022 04; 61(17):e202117330. doi: 10.1002/anie.202117330. [PMID: 35150468]
  • Vanessa S D Gomes, Renato E F Boto, Paulo Almeida, Paulo J G Coutinho, Mário Rui Pereira, M Sameiro T Gonçalves, Lucinda V Reis. Squaraine dyes as serum albumins probes: Synthesis, photophysical experiments and molecular docking studies. Bioorganic chemistry. 2021 10; 115(?):105221. doi: 10.1016/j.bioorg.2021.105221. [PMID: 34364053]
  • Yogesh Yadav, Eric Owens, Shinsuke Nomura, Takeshi Fukuda, Yoonji Baek, Satoshi Kashiwagi, Hak Soo Choi, Maged Henary. Ultrabright and Serum-Stable Squaraine Dyes. Journal of medicinal chemistry. 2020 09; 63(17):9436-9445. doi: 10.1021/acs.jmedchem.0c00617. [PMID: 32787096]
  • Cosmin Butnarasu, Nadia Barbero, Claudia Barolo, Sonja Visentin. Squaraine dyes as fluorescent turn-on sensors for the detection of porcine gastric mucin: A spectroscopic and kinetic study. Journal of photochemistry and photobiology. B, Biology. 2020 Apr; 205(?):111838. doi: 10.1016/j.jphotobiol.2020.111838. [PMID: 32142996]
  • William E Meador, Shane A Autry, Riley N Bessetti, Jacqueline N Gayton, Alex S Flynt, Nathan I Hammer, Jared H Delcamp. Water-Soluble NIR Absorbing and Emitting Indolizine Cyanine and Indolizine Squaraine Dyes for Biological Imaging. The Journal of organic chemistry. 2020 03; 85(6):4089-4095. doi: 10.1021/acs.joc.9b03108. [PMID: 32037825]
  • Nadia Barbero, Cosmin Butnarasu, Sonja Visentin, Claudia Barolo. Squaraine Dyes: Interaction with Bovine Serum Albumin to Investigate Supramolecular Adducts with Aggregation-Induced Emission (AIE) Properties. Chemistry, an Asian journal. 2019 Mar; 14(6):896-903. doi: 10.1002/asia.201900055. [PMID: 30645031]
  • Ziming Zheng, Hongjuan Li, Shiguo Sun, Yongqian Xu. Media Dependent Switching of Selectivity and Continuous near Infrared Turn-on Fluorescence Response through Cascade Interactions from Noncovalent to Covalent Binding for Detection of Serum Albumin in Living Cells. ACS applied materials & interfaces. 2018 Dec; 10(51):44336-44343. doi: 10.1021/acsami.8b19768. [PMID: 30514088]
  • Shue Mei Ng, Xiangyang Wu, M Faisal Khyasudeen, Paweł J Nowakowski, Howe-Siang Tan, Bengang Xing, Edwin K L Yeow. Vancomycin Determination by Disrupting Electron-Transfer in a Fluorescence Turn-On Squaraine-Anthraquinone Triad. ACS sensors. 2018 06; 3(6):1156-1163. doi: 10.1021/acssensors.8b00188. [PMID: 29792330]
  • Mayeul Collot, Rémy Kreder, Anatoliy L Tatarets, Leonid D Patsenker, Yves Mely, Andrey S Klymchenko. Bright fluorogenic squaraines with tuned cell entry for selective imaging of plasma membrane vs. endoplasmic reticulum. Chemical communications (Cambridge, England). 2015 Dec; 51(96):17136-9. doi: 10.1039/c5cc06094j. [PMID: 26455447]
  • Iuliia A Karpenko, Mayeul Collot, Ludovic Richert, Christel Valencia, Pascal Villa, Yves Mély, Marcel Hibert, Dominique Bonnet, Andrey S Klymchenko. Fluorogenic squaraine dimers with polarity-sensitive folding as bright far-red probes for background-free bioimaging. Journal of the American Chemical Society. 2015 Jan; 137(1):405-12. doi: 10.1021/ja5111267. [PMID: 25506627]
  • Fei-Fei An, Zi-Jian Deng, Jun Ye, Jin-Feng Zhang, Yin-Long Yang, Chang-Hui Li, Cai-Jun Zheng, Xiao-Hong Zhang. Aggregation-induced near-infrared absorption of squaraine dye in an albumin nanocomplex for photoacoustic tomography in vivo. ACS applied materials & interfaces. 2014 Oct; 6(20):17985-92. doi: 10.1021/am504816h. [PMID: 25223319]
  • M S Soumya, K M Shafeekh, Suresh Das, Annie Abraham. Symmetrical diiodinated squaraine as an efficient photosensitizer for PDT applications: Evidence from photodynamic and toxicological aspects. Chemico-biological interactions. 2014 Oct; 222(?):44-9. doi: 10.1016/j.cbi.2014.08.006. [PMID: 25168848]
  • Palapuravan Anees, Sivaramapanicker Sreejith, Ayyappanpillai Ajayaghosh. Self-assembled near-infrared dye nanoparticles as a selective protein sensor by activation of a dormant fluorophore. Journal of the American Chemical Society. 2014 Sep; 136(38):13233-9. doi: 10.1021/ja503850b. [PMID: 25199066]
  • Fu-Ping Gao, Yao-Xin Lin, Li-Li Li, Ya Liu, Ulrich Mayerhöffer, Peter Spenst, Ji-Guo Su, Jing-Yuan Li, Frank Würthner, Hao Wang. Supramolecular adducts of squaraine and protein for noninvasive tumor imaging and photothermal therapy in vivo. Biomaterials. 2014 Jan; 35(3):1004-14. doi: 10.1016/j.biomaterials.2013.10.039. [PMID: 24169004]
  • Yuanwei Zhang, Xiling Yue, Bosung Kim, Sheng Yao, Mykhailo V Bondar, Kevin D Belfield. Bovine serum albumin nanoparticles with fluorogenic near-IR-emitting squaraine dyes. ACS applied materials & interfaces. 2013 Sep; 5(17):8710-7. doi: 10.1021/am402361w. [PMID: 23992402]
  • Yongqian Xu, Andrey Malkovskiy, Yi Pang. A graphene binding-promoted fluorescence enhancement for bovine serum albumin recognition. Chemical communications (Cambridge, England). 2011 Jun; 47(23):6662-4. doi: 10.1039/c1cc11355k. [PMID: 21559544]
  • Yongqian Xu, Zhiyong Li, Andrey Malkovskiy, Shiguo Sun, Yi Pang. Aggregation control of squaraines and their use as near-infrared fluorescent sensors for protein. The journal of physical chemistry. B. 2010 Jul; 114(25):8574-80. doi: 10.1021/jp1029536. [PMID: 20524700]
  • Vadakkancheril S Jisha, Kalliat T Arun, Mahesh Hariharan, Danaboyina Ramaiah. Site-selective interactions: squaraine dye-serum albumin complexes with enhanced fluorescence and triplet yields. The journal of physical chemistry. B. 2010 May; 114(17):5912-9. doi: 10.1021/jp100369x. [PMID: 20380473]
  • Kateryna D Volkova, Vladyslava B Kovalska, Mykhaylo Yu Losytskyy, Artur Bento, Lucinda V Reis, Paulo F Santos, Paulo Almeida, Sergiy M Yarmoluk. Studies of benzothiazole and benzoselenazole squaraines as fluorescent probes for albumins detection. Journal of fluorescence. 2008 Sep; 18(5):877-82. doi: 10.1007/s10895-008-0317-2. [PMID: 18204936]
  • Keitaro Umezawa, Daniel Citterio, Koji Suzuki. Water-soluble NIR fluorescent probes based on squaraine and their application for protein labeling. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry. 2008 Feb; 24(2):213-7. doi: 10.2116/analsci.24.213. [PMID: 18270411]
  • Sivaramapanicker Sreejith, Kizhumuri P Divya, Ayyappanpillai Ajayaghosh. A near-infrared squaraine dye as a latent ratiometric fluorophore for the detection of aminothiol content in blood plasma. Angewandte Chemie (International ed. in English). 2008; 47(41):7883-7. doi: 10.1002/anie.200803194. [PMID: 18781571]
  • Easwaran Arunkumar, Na Fu, Bradley D Smith. Squaraine-derived rotaxanes: highly stable, fluorescent near-IR dyes. Chemistry (Weinheim an der Bergstrasse, Germany). 2006 Jun; 12(17):4684-90. doi: 10.1002/chem.200501541. [PMID: 16575935]
  • Vadakkancheril S Jisha, Kalliat T Arun, Mahesh Hariharan, Danaboyina Ramaiah. Site-selective binding and dual mode recognition of serum albumin by a squaraine dye. Journal of the American Chemical Society. 2006 May; 128(18):6024-5. doi: 10.1021/ja061301x. [PMID: 16669657]
  • Jose V Ros-Lis, Beatriz García, Diego Jiménez, Ramón Martínez-Máñez, Félix Sancenón, Juan Soto, Fernando Gonzalvo, M Carmen Valldecabres. Squaraines as fluoro-chromogenic probes for thiol-containing compounds and their application to the detection of biorelevant thiols. Journal of the American Chemical Society. 2004 Apr; 126(13):4064-5. doi: 10.1021/ja031987i. [PMID: 15053569]