3-Butylphthalic acid (BioDeep_00000173873)
human metabolite blood metabolite
代谢物信息卡片
化学式: C12H14O4 (222.0892)
中文名称:
谱图信息:
最多检出来源 Mus musculus(blood) 83.33%
分子结构信息
SMILES: CCCCC1=C(C(=CC=C1)C(=O)O)C(=O)O
InChI: InChI=1S/C12H14O4/c1-2-3-5-8-6-4-7-9(11(13)14)10(8)12(15)16/h4,6-7H,2-3,5H2,1H3,(H,13,14)(H,15,16)
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
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BioCyc(0)
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Plant Reactome(0)
INOH(0)
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1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Haemin Choi, Joohoon Kim, Yeongjae Im, Sanghouck Lee, Yunje Kim. The association between some endocrine disruptors and hypospadias in biological samples.
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering.
2012; 47(13):2173-9. doi:
10.1080/10934529.2012.680387. [PMID: 22871016] - Humberto M Spindola, Leila Servat, Carina Denny, Rodney A F Rodrigues, Marcos N Eberlin, Elaine Cabral, Ilza M O Sousa, Jorge Y Tamashiro, João E Carvalho, Mary A Foglio. Antinociceptive effect of geranylgeraniol and 6alpha,7beta-dihydroxyvouacapan-17beta-oate methyl ester isolated from Pterodon pubescens Benth.
BMC pharmacology.
2010 Jan; 10(?):1. doi:
10.1186/1471-2210-10-1. [PMID: 20055987] - Holger M Koch, Kerstin Becker, Matthias Wittassek, Margarete Seiwert, Jürgen Angerer, Marike Kolossa-Gehring. Di-n-butylphthalate and butylbenzylphthalate - urinary metabolite levels and estimated daily intakes: pilot study for the German Environmental Survey on children.
Journal of exposure science & environmental epidemiology.
2007 Jul; 17(4):378-87. doi:
10.1038/sj.jes.7500526. [PMID: 17006438] - Tina Mose, Lisbeth E Knudsen, Morten Hedegaard, Gerda K Mortensen. Transplacental transfer of monomethyl phthalate and mono(2-ethylhexyl) phthalate in a human placenta perfusion system.
International journal of toxicology.
2007 May; 26(3):221-9. doi:
10.1080/10915810701352721. [PMID: 17564903] - John J Kremer, Carla C Williams, Horace D Parkinson, Susan J Borghoff. Pharmacokinetics of monobutylphthalate, the active metabolite of di-n-butylphthalate, in pregnant rats.
Toxicology letters.
2005 Nov; 159(2):144-53. doi:
10.1016/j.toxlet.2005.05.006. [PMID: 15994034] - Michael E Wyde, Shaun E Kirwan, Fan Zhang, Ashley Laughter, Holly B Hoffman, Erika Bartolucci-Page, Kevin W Gaido, Bingfang Yan, Li You. Di-n-butyl phthalate activates constitutive androstane receptor and pregnane X receptor and enhances the expression of steroid-metabolizing enzymes in the liver of rat fetuses.
Toxicological sciences : an official journal of the Society of Toxicology.
2005 Aug; 86(2):281-90. doi:
10.1093/toxsci/kfi204. [PMID: 15901914] - Holger M Koch, Ralf Preuss, Hans Drexler, Jürgen Angerer. Exposure of nursery school children and their parents and teachers to di-n-butylphthalate and butylbenzylphthalate.
International archives of occupational and environmental health.
2005 Apr; 78(3):223-9. doi:
10.1007/s00420-004-0570-x. [PMID: 15776263] - Timothy R Fennell, Wojciech L Krol, Susan C J Sumner, Rodney W Snyder. Pharmacokinetics of dibutylphthalate in pregnant rats.
Toxicological sciences : an official journal of the Society of Toxicology.
2004 Dec; 82(2):407-18. doi:
10.1093/toxsci/kfh294. [PMID: 15456918] - W A Anderson, L Castle, M J Scotter, R C Massey, C Springall. A biomarker approach to measuring human dietary exposure to certain phthalate diesters.
Food additives and contaminants.
2001 Dec; 18(12):1068-74. doi:
10.1080/02652030110050113. [PMID: 11761117] - J P Payan, J P Marty, J P Fabry, D Beydon, I Boudry, E Ferrari, F Canel, M C Grandclaude, C M Vincent. In vivo and in vitro percutaneous absorption of [(14)C]di-N-butylphthalate in rat.
Drug metabolism and disposition: the biological fate of chemicals.
2001 Jun; 29(6):843-54. doi:
NULL. [PMID: 11353753]
