3-Aminobenzanthrone (BioDeep_00000173861)
human metabolite blood metabolite
代谢物信息卡片
化学式: C17H11NO (245.0840596)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 93.75%
分子结构信息
SMILES: C1=CC=C2C(=C1)C3=C4C(=C(C=C3)N)C=CC=C4C2=O
InChI: InChI=1S/C17H11NO/c18-15-9-8-11-10-4-1-2-5-12(10)17(19)14-7-3-6-13(15)16(11)14/h1-9H,18H2
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Jana Mizerovská, Helena Dračínská, Eva Frei, Heinz H Schmeiser, Volker M Arlt, Marie Stiborová. Induction of biotransformation enzymes by the carcinogenic air-pollutant 3-nitrobenzanthrone in liver, kidney and lung, after intra-tracheal instillation in rats.
Mutation research.
2011 Feb; 720(1-2):34-41. doi:
10.1016/j.mrgentox.2010.12.003. [PMID: 21167309] - Inta Kalnina, Ruta Bruvere, Tija Zvagule, Natalija Gabruseva, Laura Klimkane, Elena Kirilova, Imants Meirovics, Gunta Kizane. Fluorescent probe ABM and estimation of immune state in patients with different pathologies (review article).
Journal of fluorescence.
2010 Jan; 20(1):9-17. doi:
10.1007/s10895-009-0515-6. [PMID: 19649695] - Marie Stiborová, Helena Dracínská, Markéta Martínková, Jana Mizerovská, Jirí Hudecek, Petr Hodek, Jirí Liberda, Eva Frei, Heinz H Schmeiser, David H Phillips, Volker M Arlt. 3-aminobenzanthrone, a human metabolite of the carcinogenic environmental pollutant 3-nitrobenzanthrone, induces biotransformation enzymes in rat kidney and lung.
Mutation research.
2009 May; 676(1-2):93-101. doi:
10.1016/j.mrgentox.2009.04.013. [PMID: 19398038] - Marie Stiborová, Helena Dracínská, Jana Mizerovská, Eva Frei, Heinz H Schmeiser, Jirí Hudecek, Petr Hodek, David H Phillips, Volker M Arlt. The environmental pollutant and carcinogen 3-nitrobenzanthrone induces cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase in rat lung and kidney, thereby enhancing its own genotoxicity.
Toxicology.
2008 May; 247(1):11-22. doi:
10.1016/j.tox.2008.01.018. [PMID: 18329153] - Volker M Arlt, Colin J Henderson, C Roland Wolf, Heinz H Schmeiser, David H Phillips, Marie Stiborova. Bioactivation of 3-aminobenzanthrone, a human metabolite of the environmental pollutant 3-nitrobenzanthrone: evidence for DNA adduct formation mediated by cytochrome P450 enzymes and peroxidases.
Cancer letters.
2006 Mar; 234(2):220-31. doi:
10.1016/j.canlet.2005.03.035. [PMID: 15885895] - Volker M Arlt, Alan Hewer, Bernd L Sorg, Heinz H Schmeiser, David H Phillips, Marie Stiborova. 3-aminobenzanthrone, a human metabolite of the environmental pollutant 3-nitrobenzanthrone, forms DNA adducts after metabolic activation by human and rat liver microsomes: evidence for activation by cytochrome P450 1A1 and P450 1A2.
Chemical research in toxicology.
2004 Aug; 17(8):1092-101. doi:
10.1021/tx049912v. [PMID: 15310241]