3-Aminoadipic acid (BioDeep_00000173858)
human metabolite blood metabolite
代谢物信息卡片
HO2CCH2CH2CH(NH2)CH2CO2H
化学式: C6H11NO4 (161.0688046)
中文名称: 3-氨基己二酸
谱图信息:
最多检出来源 Homo sapiens(blood) 70.59%
分子结构信息
SMILES: C(CC(=O)O)C(CC(=O)O)N
InChI: InChI=1S/C6H11NO4/c7-4(3-6(10)11)1-2-5(8)9/h4H,1-3,7H2,(H,8,9)(H,10,11)
描述信息
同义名列表
17 个代谢物同义名
HO2CCH2CH2CH(NH2)CH2CO2H; 3-Aminohexanedioic acid; beta-Homoglutamic acid; beta-Aminoadipic acid; b-Homoglutamic acid; Β-homoglutamic acid; b-Aminoadipic acid; beta-Homoglutamate; 3-aminoadipic acid; Β-aminoadipic acid; beta-Aminoadipate; b-Homoglutamate; Β-homoglutamate; Β-aminoadipate; b-Aminoadipate; 3-Aminoadipate; BAad
数据库引用编号
6 个数据库交叉引用编号
- ChEBI: CHEBI:64303
- PubChem: 224389
- HMDB: HMDB0245812
- chemspider: 194969
- CAS: 40967-78-0
- CAS: 5427-96-3
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Yueqiang Leng, Shaobin Zhong. Sfp-type 4'-phosphopantetheinyl transferase is required for lysine synthesis, tolerance to oxidative stress and virulence in the plant pathogenic fungus Cochliobolus sativus.
Molecular plant pathology.
2012 May; 13(4):375-87. doi:
10.1111/j.1364-3703.2011.00756.x. [PMID: 22023083] - Philipp Wiemann, Sabine Albermann, Eva-Maria Niehaus, Lena Studt, Katharina W von Bargen, Nelson L Brock, Hans-Ulrich Humpf, Jeroen S Dickschat, Bettina Tudzynski. The Sfp-type 4'-phosphopantetheinyl transferase Ppt1 of Fusarium fujikuroi controls development, secondary metabolism and pathogenicity.
PloS one.
2012; 7(5):e37519. doi:
10.1371/journal.pone.0037519. [PMID: 22662164] - Desmond B S Pink, Stephanie K Gatrell, Rajavel Elango, Joan Turchinsky, Aaron S Kiess, Kenneth P Blemings, Walter T Dixon, Ronald O Ball. Lysine α-ketoglutarate reductase, but not saccharopine dehydrogenase, is subject to substrate inhibition in pig liver.
Nutrition research (New York, N.Y.).
2011 Jul; 31(7):544-54. doi:
10.1016/j.nutres.2011.06.001. [PMID: 21840471] - Sven W Sauer, Silvana Opp, Georg F Hoffmann, David M Koeller, Jürgen G Okun, Stefan Kölker. Therapeutic modulation of cerebral L-lysine metabolism in a mouse model for glutaric aciduria type I.
Brain : a journal of neurology.
2011 Jan; 134(Pt 1):157-70. doi:
10.1093/brain/awq269. [PMID: 20923787] - Kathryn E Bushley, B Gillian Turgeon. Phylogenomics reveals subfamilies of fungal nonribosomal peptide synthetases and their evolutionary relationships.
BMC evolutionary biology.
2010 Jan; 10(?):26. doi:
10.1186/1471-2148-10-26. [PMID: 20100353] - Matthias L Schroeter, Hashim Abdul-Khaliq, Julia Sacher, Johann Steiner, Ingolf E Blasig, Karsten Mueller. Mood disorders are glial disorders: evidence from in vivo studies.
Cardiovascular psychiatry and neurology.
2010; 2010(?):780645. doi:
10.1155/2010/780645. [PMID: 20585358] - Yulan Wang, Shu-Hua Xiao, Jian Xue, Burton H Singer, Jürg Utzinger, Elaine Holmes. Systems metabolic effects of a necator americanus infection in Syrian hamster.
Journal of proteome research.
2009 Dec; 8(12):5442-50. doi:
10.1021/pr900711j. [PMID: 19810771] - Ralf Horbach, Alexander Graf, Fabian Weihmann, Luis Antelo, Sebastian Mathea, Johannes C Liermann, Till Opatz, Eckhard Thines, Jesús Aguirre, Holger B Deising. Sfp-type 4'-phosphopantetheinyl transferase is indispensable for fungal pathogenicity.
The Plant cell.
2009 Oct; 21(10):3379-96. doi:
10.1105/tpc.108.064188. [PMID: 19880801] - Banzragch Battur, Damdinsuren Boldbaatar, Rika Umemiya-Shirafuji, Min Liao, Badgar Battsetseg, DeMar Taylor, Badarch Baymbaa, Kozo Fujisaki. LKR/SDH plays important roles throughout the tick life cycle including a long starvation period.
PloS one.
2009 Sep; 4(9):e7136. doi:
10.1371/journal.pone.0007136. [PMID: 19774086] - Claudie Hooper, Fleur Pinteaux-Jones, Victoria A H Fry, Ioanna G Sevastou, David Baker, Simon J Heales, Jennifer M Pocock. Differential effects of albumin on microglia and macrophages; implications for neurodegeneration following blood-brain barrier damage.
Journal of neurochemistry.
2009 May; 109(3):694-705. doi:
10.1111/j.1471-4159.2009.05953.x. [PMID: 19187440] - M Moulin, C Deleu, F Larher, A Bouchereau. The lysine-ketoglutarate reductase-saccharopine dehydrogenase is involved in the osmo-induced synthesis of pipecolic acid in rapeseed leaf tissues.
Plant physiology and biochemistry : PPB.
2006 Jul; 44(7-9):474-82. doi:
10.1016/j.plaphy.2006.08.005. [PMID: 17023168] - Sarah Garrod, Mary E Bollard, Andrew W Nicholls, Susan C Connor, John Connelly, Jeremy K Nicholson, Elaine Holmes. Integrated metabonomic analysis of the multiorgan effects of hydrazine toxicity in the rat.
Chemical research in toxicology.
2005 Feb; 18(2):115-22. doi:
10.1021/tx0498915. [PMID: 15720114] - J Varga, S Kocsubé, Beáta Tóth, A Mesterházy. Nonribosomal peptide synthetase genes in the genome of Fusarium graminearum, causative agent of wheat head blight.
Acta biologica Hungarica.
2005; 56(3-4):375-88. doi:
10.1556/abiol.56.2005.3-4.19. [PMID: 16196211] - Arthur J L Cooper. The role of glutamine transaminase K (GTK) in sulfur and alpha-keto acid metabolism in the brain, and in the possible bioactivation of neurotoxicants.
Neurochemistry international.
2004 Jun; 44(8):557-77. doi:
10.1016/j.neuint.2003.12.002. [PMID: 15016471] - Aymeric Goyer, Tanya L Johnson, Laura J Olsen, Eva Collakova, Yair Shachar-Hill, David Rhodes, Andrew D Hanson. Characterization and metabolic function of a peroxisomal sarcosine and pipecolate oxidase from Arabidopsis.
The Journal of biological chemistry.
2004 Apr; 279(17):16947-53. doi:
10.1074/jbc.m400071200. [PMID: 14766747] - Hirotaka Matsuo, Yoshikatsu Kanai, Ju Young Kim, Arthit Chairoungdua, Do Kyung Kim, Jun Inatomi, Yasuhiro Shigeta, Hisako Ishimine, Sophapun Chaekuntode, Kittipong Tachampa, Hye Won Choi, Ellappan Babu, Jun Fukuda, Hitoshi Endou. Identification of a novel Na+-independent acidic amino acid transporter with structural similarity to the member of a heterodimeric amino acid transporter family associated with unknown heavy chains.
The Journal of biological chemistry.
2002 Jun; 277(23):21017-26. doi:
10.1074/jbc.m200019200. [PMID: 11907033] - Chuang Chih-Kuang, Lin Shuan-Pei, Lee Shyue-Jye, Wang Tuan-Jen. Plasma free amino acids in Taiwan Chinese: the effect of age.
Clinical chemistry and laboratory medicine.
2002 Apr; 40(4):378-82. doi:
10.1515/cclm.2002.061. [PMID: 12059079] - A W Nicholls, E Holmes, J C Lindon, J P Shockcor, R D Farrant, J N Haselden, S J Damment, C J Waterfield, J K Nicholson. Metabonomic investigations into hydrazine toxicity in the rat.
Chemical research in toxicology.
2001 Aug; 14(8):975-87. doi:
10.1021/tx000231j. [PMID: 11511171]
