2,9-Dimethyl-4,7-diphenyl-1,10-phenanthroline (BioDeep_00000173610)
human metabolite blood metabolite Volatile Flavor Compounds
代谢物信息卡片
化学式: C26H20N2 (360.16264)
中文名称: 浴铜灵, 2,9-二甲基-4,7-联苯-1,10-邻二氮杂菲
谱图信息:
最多检出来源 Homo sapiens(blood) 98.21%
分子结构信息
SMILES: CC1=CC(=C2C=CC3=C(C=C(N=C3C2=N1)C)C4=CC=CC=C4)C5=CC=CC=C5
InChI: InChI=1S/C26H20N2/c1-17-15-23(19-9-5-3-6-10-19)21-13-14-22-24(20-11-7-4-8-12-20)16-18(2)28-26(22)25(21)27-17/h3-16H,1-2H3
描述信息
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents
D000975 - Antioxidants > D016166 - Free Radical Scavengers
D020011 - Protective Agents > D000975 - Antioxidants
同义名列表
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Lukáš Smolko, Romana Smolková, Erika Samoľová, Ibrahim Morgan, Mohamad Saoud, Goran N Kaluđerović. Two isostructural Co(II) flufenamato and niflumato complexes with bathocuproine: Analogues with a different cytotoxic activity.
Journal of inorganic biochemistry.
2020 09; 210(?):111160. doi:
10.1016/j.jinorgbio.2020.111160. [PMID: 32717439] - Shin Muramoto, Derk Rading, Brian Bush, Greg Gillen, David G Castner. Low-temperature plasma for compositional depth profiling of crosslinking organic multilayers: comparison with C60 and giant argon gas cluster sources.
Rapid communications in mass spectrometry : RCM.
2014 Sep; 28(18):1971-8. doi:
10.1002/rcm.6981. [PMID: 25132297] - H Zubair, H Y Khan, A Sohail, S Azim, M F Ullah, A Ahmad, F H Sarkar, S M Hadi. Redox cycling of endogenous copper by thymoquinone leads to ROS-mediated DNA breakage and consequent cell death: putative anticancer mechanism of antioxidants.
Cell death & disease.
2013 Jun; 4(?):e660. doi:
10.1038/cddis.2013.172. [PMID: 23744360] - Douglas Ganini, Donatella Canistro, JinJie Jiang, JinJie Jang, Krisztian Stadler, Ronald P Mason, Maria B Kadiiska. Ceruloplasmin (ferroxidase) oxidizes hydroxylamine probes: deceptive implications for free radical detection.
Free radical biology & medicine.
2012 Oct; 53(7):1514-21. doi:
10.1016/j.freeradbiomed.2012.07.013. [PMID: 22824865] - Kazuo Sakai, Satoko Kino, Masao Takeuchi, Tairin Ochi, Giuseppe Da Cruz, Isao Tomita. Analysis of antioxidant activities in vegetable oils and fat soluble vitamins and biofactors by the PAO-SO method.
Methods in molecular biology (Clifton, N.J.).
2010; 594(?):241-50. doi:
10.1007/978-1-60761-411-1_16. [PMID: 20072921] - Uzma Shamim, Sarmad Hanif, M F Ullah, Asfar S Azmi, Showket H Bhat, S M Hadi. Plant polyphenols mobilize nuclear copper in human peripheral lymphocytes leading to oxidatively generated DNA breakage: implications for an anticancer mechanism.
Free radical research.
2008 Aug; 42(8):764-72. doi:
10.1080/10715760802302251. [PMID: 18661438] - Sarmad Hanif, Uzma Shamim, M F Ullah, Asfar S Azmi, Showket H Bhat, S M Hadi. The anthocyanidin delphinidin mobilizes endogenous copper ions from human lymphocytes leading to oxidative degradation of cellular DNA.
Toxicology.
2008 Jul; 249(1):19-25. doi:
10.1016/j.tox.2008.03.024. [PMID: 18486296] - Aphrodite Caragounis, Tai Du, Gulay Filiz, Katrina M Laughton, Irene Volitakis, Robyn A Sharples, Robert A Cherny, Colin L Masters, Simon C Drew, Andrew F Hill, Qiao-Xin Li, Peter J Crouch, Kevin J Barnham, Anthony R White. Differential modulation of Alzheimer's disease amyloid beta-peptide accumulation by diverse classes of metal ligands.
The Biochemical journal.
2007 Nov; 407(3):435-50. doi:
10.1042/bj20070579. [PMID: 17680773] - Sruti Shiva, Xunde Wang, Lorna A Ringwood, Xueying Xu, Susan Yuditskaya, Vidhya Annavajjhala, Hiroaki Miyajima, Neil Hogg, Zena Leah Harris, Mark T Gladwin. Ceruloplasmin is a NO oxidase and nitrite synthase that determines endocrine NO homeostasis.
Nature chemical biology.
2006 Sep; 2(9):486-93. doi:
10.1038/nchembio813. [PMID: 16906150] - Shinji Oikawa, Emiko Nagao, Katsuhisa Sakano, Shosuke Kawanishi. Mechanism of oxidative DNA damage induced by capsaicin, a principal ingredient of hot chili pepper.
Free radical research.
2006 Sep; 40(9):966-73. doi:
10.1080/10715760600827483. [PMID: 17015277] - Jung Hoon Kang. Oxidative modification of human ceruloplasmin by methylglyoxal: an in vitro study.
Journal of biochemistry and molecular biology.
2006 May; 39(3):335-8. doi:
10.5483/bmbrep.2006.39.3.335. [PMID: 16756764] - Shino Homma-Takeda, Yusuke Hiraku, Yasuhiro Ohkuma, Shinji Oikawa, Mariko Murata, Kazuhiko Ogawa, Taeko Iwamuro, Song Li, Gui Fan Sun, Yoshito Kumagai, Nobuhiro Shimojo, Shosuke Kawanishi. 2,4,6-trinitrotoluene-induced reproductive toxicity via oxidative DNA damage by its metabolite.
Free radical research.
2002 May; 36(5):555-66. doi:
10.1080/10715760290025933. [PMID: 12150543] - Kenneth Kam-Wing Lo, Wai-Ki Hui, Dominic Chun-Ming Ng, Kung-Kai Cheung. Synthesis, characterization, photophysical properties, and biological labeling studies of a series of luminescent rhenium(I) polypyridine maleimide complexes.
Inorganic chemistry.
2002 Jan; 41(1):40-6. doi:
10.1021/ic010602z. [PMID: 11782142] - I Pinchuk, S Gal, D Lichtenberg. The dose-dependent effect of copper-chelating agents on the kinetics of peroxidation of low-density lipoprotein (LDL).
Free radical research.
2001 Apr; 34(4):349-62. doi:
10.1080/10715760100300301. [PMID: 11328672] - A I Ivanov, J A Parkinson, E Cossins, J Woodrow, P J Sadler. Bathocuproine-assisted reduction of copper(II) by human albumin.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry.
2000 Feb; 5(1):102-9. doi:
10.1007/s007750050013. [PMID: 10766442] - R P Patel, D Svistunenko, M T Wilson, V M Darley-Usmar. Reduction of Cu(II) by lipid hydroperoxides: implications for the copper-dependent oxidation of low-density lipoprotein.
The Biochemical journal.
1997 Mar; 322 ( Pt 2)(?):425-33. doi:
10.1042/bj3220425. [PMID: 9065759] - M J Bingham, T J Ong, W J Ingledew, H J McArdle. ATP-dependent copper transporter, in the Golgi apparatus of rat hepatocytes, transports Cu(II) not Cu(I).
The American journal of physiology.
1996 Nov; 271(5 Pt 1):G741-6. doi:
10.1152/ajpgi.1996.271.5.g741. [PMID: 8944686] - D Ross, P Moldeus, H Sies, M T Smith. Mechanism and relevance of glutathione mutagenicity.
Mutation research.
1986 Nov; 175(3):127-31. doi:
10.1016/0165-7992(86)90110-7. [PMID: 2877394]