Macamide B (BioDeep_00000017360)
Secondary id: BioDeep_00000623126
human metabolite PANOMIX_OTCML-2023 Endogenous
代谢物信息卡片
化学式: C23H39NO (345.3031484)
中文名称: N-苄基十六烷酰胺, 玛卡酰胺 B, N-苄基棕榈酰胺
谱图信息:
最多检出来源 Chinese Herbal Medicine(otcml) 0.81%
分子结构信息
SMILES: C(CCCCCCCCCCCCCCC)(=O)NCC1C=CC=CC=1
InChI: InChI=1S/C23H39NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-17-20-23(25)24-21-22-18-15-14-16-19-22/h14-16,18-19H,2-13,17,20-21H2,1H3,(H,24,25)
描述信息
N-benzylhexadecanamide is a macamide resulting from the formal condensation of the carboxy group of hexadecanoic acid with benzylamine. A moderate inhibitor of fatty acid amide hydrolase. It has a role as a neuroprotective agent, a plant metabolite and an EC 3.5.1.99 (fatty acid amide hydrolase) inhibitor. It is a secondary carboxamide and a macamide. It is functionally related to a hexadecanoic acid and a benzylamine.
N-benzylpalmitamide is a natural product found in Lepidium meyenii with data available.
See also: Lepidium meyenii root (part of).
A macamide resulting from the formal condensation of the carboxy group of hexadecanoic acid with benzylamine. A moderate inhibitor of fatty acid amide hydrolase.
Macamide B is found in root vegetables. Macamide B is an alkaloid from the tubers of Lepidium meyenii (maca).
Alkaloid from the tubers of Lepidium meyenii (maca). Macamide B is found in root vegetables.
Macamide B (N-Benzylhexadecanamide; Macamide 1) is a macamide isolated from Lepidium meyenii, acts as an inhibitor of fatty acid amide hydrolase (FAAH).
N-Benzylpalmitamide is a macamide isolated from Lepidium meyenii, acts as an inhibitor of fatty acid amide hydrolase (FAAH).
N-Benzylpalmitamide is a macamide isolated from Lepidium meyenii, acts as an inhibitor of fatty acid amide hydrolase (FAAH).
同义名列表
16 个代谢物同义名
N-Benzylhexadecanamide;Macamide 1; Hexadecanamide, N-(phenylmethyl)-; N-(Phenylmethyl)-hexadecanamide; MLGPKWUKOQAAGI-UHFFFAOYSA-N; N-hexadecanoyl benzylamine; Hexadecanamide, N-benzyl-; N-Benzyl Hexadecanamide; N-benzylhexadecanamide; N-benzylpalmitamide; UNII-1M5UVS8JUU; 1M5UVS8JUU; Macamide B; Macamide 1; MacamideB; Macamide; NA 23:4
数据库引用编号
14 个数据库交叉引用编号
- ChEBI: CHEBI:140849
- PubChem: 11198769
- HMDB: HMDB0039954
- ChEMBL: CHEMBL2415102
- LipidMAPS: LMFA08020155
- MeSH: N-benzylhexadecanamide
- ChemIDplus: 0074058712
- KNApSAcK: C00054026
- foodb: FDB019617
- chemspider: 9373838
- CAS: 74058-71-2
- medchemexpress: HY-N2365
- PMhub: MS000202764
- MetaboLights: MTBLC140849
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
3 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Nalin Singh, Bogdan Barnych, Christophe Morisseau, Karen M Wagner, Debin Wan, Ashley Takeshita, Hoang Pham, Ting Xu, Abhaya Dandekar, Jun-Yan Liu, Bruce D Hammock. N-Benzyl-linoleamide, a Constituent of Lepidium meyenii (Maca), Is an Orally Bioavailable Soluble Epoxide Hydrolase Inhibitor That Alleviates Inflammatory Pain.
Journal of natural products.
2020 12; 83(12):3689-3697. doi:
10.1021/acs.jnatprod.0c00938
. [PMID: 33320645] - Yan-Qing Ye, Zu-Hong Ma, Qiao-Fen Yang, Yan-Qi Sun, Rui-Qi Zhang, Run-Fang Wu, Xin Ren, Li-Juan Mu, Zhi-Yong Jiang, Min Zhou. Isolation and synthesis of a new benzylated alkamide from the roots of Lepidium meyenii.
Natural product research.
2019 Oct; 33(19):2731-2737. doi:
10.1080/14786419.2018.1499633
. [PMID: 30124345] - Yanyan Zhou, Hongjie Wang, Feifei Guo, Nan Si, Adelheid Brantner, Jian Yang, Lingyu Han, Xiaolu Wei, Haiyu Zhao, Baolin Bian. Integrated Proteomics and Lipidomics Investigation of the Mechanism Underlying the Neuroprotective Effect of N-benzylhexadecanamide.
Molecules (Basel, Switzerland).
2018 Nov; 23(11):. doi:
10.3390/molecules23112929
. [PMID: 30424008] - Hui Wu, Charles J Kelley, Alejandro Pino-Figueroa, Huyen D Vu, Timothy J Maher. Macamides and their synthetic analogs: evaluation of in vitro FAAH inhibition.
Bioorganic & medicinal chemistry.
2013 Sep; 21(17):5188-97. doi:
10.1016/j.bmc.2013.06.034
. [PMID: 23891163] - Céline Clément, Diego A Diaz Grados, Bharathi Avula, Ihklas A Khan, Andrea C Mayer, Dante D Ponce Aguirre, Ivan Manrique, Michael Kreuzer. Influence of colour type and previous cultivation on secondary metabolites in hypocotyls and leaves of maca (Lepidium meyenii Walpers).
Journal of the science of food and agriculture.
2010 Apr; 90(5):861-9. doi:
10.1002/jsfa.3896
. [PMID: 20355123] - Megan M McCollom, Jacquelyn R Villinski, Kerry L McPhail, Lyle E Craker, Stefan Gafner. Analysis of macamides in samples of Maca (Lepidium meyenii) by HPLC-UV-MS/MS.
Phytochemical analysis : PCA.
2005 Nov; 16(6):463-9. doi:
10.1002/pca.871
. [PMID: 16315492]