2,6-Dichloro-4-nitrophenol (BioDeep_00000173598)

   

human metabolite blood metabolite


代谢物信息卡片


2,6-Dichloro-4-nitrophenol

化学式: C6H3Cl2NO3 (206.94899880000003)
中文名称: 2,6-二氯-4-硝基苯酚
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=C(C=C(C(=C1Cl)O)Cl)[N+](=O)[O-]
InChI: InChI=1S/C6H3Cl2NO3/c7-4-1-3(9(11)12)2-5(8)6(4)10/h1-2,10H

描述信息

同义名列表

2 个代谢物同义名

2,6-Dichloro-4-nitrophenol; DCNP



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Simone Perazzolo, Zachary Stephen, Masa Eguchi, Xiaolin Xu, Rachele Delle Fratte, Ann C Collier, Ann J Melvin, Rodney J Y Ho. A novel formulation enabled transformation of 3 HIV drugs tenofovir-lamivudine-dolutegravir (TLD) from short-acting to long-acting all-in-one injectable. AIDS (London, England). 2023 Aug; ?(?):. doi: 10.1097/qad.0000000000003706. [PMID: 37650755]
  • Pankaj Kumar Arora, Alok Srivastava, Sanjay Kumar Garg, Vijai Pal Singh. Recent advances in degradation of chloronitrophenols. Bioresource technology. 2018 Feb; 250(?):902-909. doi: 10.1016/j.biortech.2017.12.007. [PMID: 29229201]
  • Feng Xiao, Xiangru Zhang, Hongyan Zhai, Irene M C Lo, George L Tipoe, Mengting Yang, Yang Pan, Guanghao Chen. New halogenated disinfection byproducts in swimming pool water and their permeability across skin. Environmental science & technology. 2012 Jul; 46(13):7112-9. doi: 10.1021/es3010656. [PMID: 22697042]
  • S K Hong, D K Anestis, S Kennedy, G O Rankin. Effect of sulfation substrates/inhibitors on N-(3,5-dichlorophenyl)succinimide nephrotoxocity in Fischer 344 rats. Journal of toxicology and environmental health. Part A. 1999 May; 57(1):47-62. doi: 10.1080/009841099157854. [PMID: 10321901]
  • M Chiba, A J Schwab, C A Goresky, K S Pang. Carrier-mediated entry of 4-methylumbelliferyl sulfate: characterization by the multiple-indicator dilution technique in perfused rat liver. Hepatology (Baltimore, Md.). 1998 Jan; 27(1):134-46. doi: 10.1002/hep.510270122. [PMID: 9425929]
  • K H Sit, K P Wong. Sulphate induces very fast cell rounding and detachment. Biochimica et biophysica acta. 1991 Apr; 1092(2):180-3. doi: 10.1016/0167-4889(91)90154-p. [PMID: 2018784]
  • M L van de Poll, R B Tijdens, P Vondrácek, A P Bruins, D K Meijer, J H Meerman. The role of sulfation in the metabolic activation of N-hydroxy-4'-fluoro-4-acetylaminobiphenyl. Carcinogenesis. 1989 Dec; 10(12):2285-91. doi: 10.1093/carcin/10.12.2285. [PMID: 2480190]
  • S Teshima, Y Hayashi, M Ando. Determination of acid phosphatase in biological fluids using a new substrate, 2,6-dichloro-4-nitrophenyl phosphate. Clinica chimica acta; international journal of clinical chemistry. 1987 Sep; 168(2):231-8. doi: 10.1016/0009-8981(87)90292-0. [PMID: 3677418]
  • G J Mulder. Kinetics of sulfation in the rat in vivo and in the perfused rat liver. Federation proceedings. 1986 Jul; 45(8):2229-34. doi: NULL. [PMID: 3087784]
  • O Giorgi, J L Meek. Sulfation of peptides and simple phenols by rat brain phenolsulfotransferase. Inhibition by dichloronitrophenol. Biochemical pharmacology. 1985 Jan; 34(1):45-9. doi: 10.1016/0006-2952(85)90098-x. [PMID: 3855358]
  • G L Kedderis, M C Dyroff, D E Rickert. Hepatic macromolecular covalent binding of the hepatocarcinogen 2,6-dinitrotoluene and its 2,4-isomer in vivo: modulation by the sulfotransferase inhibitors pentachlorophenol and 2,6-dichloro-4-nitrophenol. Carcinogenesis. 1984 Sep; 5(9):1199-204. doi: 10.1093/carcin/5.9.1199. [PMID: 6590136]
  • H Koster, I Halsema, E Scholtens, J H Meerman, K S Pang, G J Mulder. Selective inhibition of sulfate conjugation in the rat: pharmacokinetics and characterization of the inhibitory effect of 2,6-dichloro-4-nitrophenol. Biochemical pharmacology. 1982 May; 31(10):1919-24. doi: 10.1016/0006-2952(82)90498-1. [PMID: 7104024]