2,5-Dihydro-1H-pyrrole-2-carboxylic acid (BioDeep_00000173584)

   

human metabolite blood metabolite


代谢物信息卡片


3,4-Dehydroproline, L-(+) tartrate salt, (S)-isomer

化学式: C5H7NO2 (113.0477)
中文名称: 3,4-脱氢-DL-脯氨酸, 2,5-二氢-1H-吡咯-2-羧酸, 脯氨酸，3,4-二脱氢
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1C=CC(N1)C(=O)O
InChI: InChI=1S/C5H7NO2/c7-5(8)4-2-1-3-6-4/h1-2,4,6H,3H2,(H,7,8)

描述信息

同义名列表

11 个代谢物同义名

3,4-Dehydroproline, L-(+) tartrate salt, (S)-isomer; 2,5-Dihydro-1H-pyrrole-2-carboxylic acid; 2,5-Dihydro-1H-pyrrole-2-carboxylate; 3,4-Dehydroproline, (+-)-isomer; L-3-Pyrroline-2-carboxylic acid; 3,4-Dehydroproline, (R)-isomer; 3,4-Dehydroproline, (S)-isomer; 3-Pyrroline-2-carboxylic acid; 3,4-Dehydroproline; 2,5-Dihydro-1H-pyrrole-2-carboxylic acid; Proline, 3,4-didehydro-



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Xuelian Zhang, Haoli Ma, Huandong Qi, Jie Zhao. Roles of hydroxyproline-rich glycoproteins in the pollen tube and style cell growth of tobacco (Nicotiana tabacum L.). Journal of plant physiology. 2014 Jul; 171(12):1036-45. doi: 10.1016/j.jplph.2014.02.010. [PMID: 24974330]
  • XueLian Zhang, Yujun Ren, Jie Zhao. Roles of extensins in cotyledon primordium formation and shoot apical meristem activity in Nicotiana tabacum. Journal of experimental botany. 2008; 59(14):4045-58. doi: 10.1093/jxb/ern245. [PMID: 18931351]
  • Maïté Vicré, Catherine Santaella, Sandrine Blanchet, Aurélien Gateau, Azeddine Driouich. Root border-like cells of Arabidopsis. Microscopical characterization and role in the interaction with rhizobacteria. Plant physiology. 2005 Jun; 138(2):998-1008. doi: 10.1104/pp.104.051813. [PMID: 15908608]
  • Dongxia Li, Maija Hirsilä, Peppi Koivunen, Mitchell C Brenner, Leon Xu, Charles Yang, Kari I Kivirikko, Johanna Myllyharju. Many amino acid substitutions in a hypoxia-inducible transcription factor (HIF)-1alpha-like peptide cause only minor changes in its hydroxylation by the HIF prolyl 4-hydroxylases: substitution of 3,4-dehydroproline or azetidine-2-carboxylic acid for the proline leads to a high rate of uncoupled 2-oxoglutarate decarboxylation. The Journal of biological chemistry. 2004 Dec; 279(53):55051-9. doi: 10.1074/jbc.m410287200. [PMID: 15485863]
  • M Bucher, B Schroeer, L Willmitzer, J W Riesmeier. Two genes encoding extension-like proteins are predominantly expressed in tomato root hair cells. Plant molecular biology. 1997 Nov; 35(4):497-508. doi: 10.1023/a:1005869717158. [PMID: 9349272]
  • J B Cooper, J E Heuser, J E Varner. 3,4-Dehydroproline inhibits cell wall assembly and cell division in tobacco protoplasts. Plant physiology. 1994 Feb; 104(2):747-52. doi: 10.1104/pp.104.2.747. [PMID: 8159790]
  • R W Leu, C A Stewart, M J Herriott, D J Fast, J A Rummage. Inhibitor of C1q secretion suppresses the macrophage response to lipid A for nitric oxide but not for TNF production: evidence for a role of C1q in autocrine binding of TNF. Immunobiology. 1993 Jul; 188(3):242-58. doi: 10.1016/s0171-2985(11)80233-0. [PMID: 8225388]
  • F Akahori, T Nagata, T Masaoka, T Okinaka. Effect of dehydroproline as a collagen synthetic inhibitor in paraquat-induced pulmonary fibrosis in beagle dogs. Veterinary and human toxicology. 1993 Jun; 35(3):216-22. doi: NULL. [PMID: 8351792]
  • R W Leu, A Q Zhou, B J Shannon, M J Herriott. Inhibitors of C1q biosynthesis suppress activation of murine macrophages for both antibody-independent and antibody-dependent tumor cytotoxicity. Journal of immunology (Baltimore, Md. : 1950). 1990 Mar; 144(6):2281-6. doi: ". [PMID: 2107257]
  • J Blankenship, S Benson. Collagen metabolism and spicule formation in sea urchin micromeres. Experimental cell research. 1984 May; 152(1):98-104. doi: 10.1016/0014-4827(84)90233-7. [PMID: 6714328]
  • M P Hacker, R A Newman, C B Hong. The effect of L-3, 4-dehydroproline on the antitumor activity and toxicity of bleomycin. Toxicology and applied pharmacology. 1983 Jun; 69(1):102-9. doi: 10.1016/0041-008x(83)90125-4. [PMID: 6190266]
  • T J Franklin, W P Morris, B E Loveday. Effects of inhibitors of collagen maturation on hypertension in rats. Blood vessels. 1982; 19(5):217-25. doi: 10.1159/000158388. [PMID: 7115983]