2,5-Anhydro-D-mannitol (BioDeep_00000173577)
human metabolite blood metabolite
代谢物信息卡片
2,5-bis(hydroxymethyl)oxolane-3,4-diol
化学式: C6H12O5 (164.0685)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 100%
分子结构信息
SMILES: C(C1C(C(C(O1)CO)O)O)O
InChI: InChI=1S/C6H12O5/c7-1-3-5(9)6(10)4(2-8)11-3/h3-10H,1-2H2
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- Xing Jin, Yupei Liang, Dan Liu, Qin Luo, Lili Cai, Jia Wu, Lijun Jia, Wen-Lian Chen. An essential role for GLUT5-mediated fructose utilization in exacerbating the malignancy of clear cell renal cell carcinoma.
Cell biology and toxicology.
2019 10; 35(5):471-483. doi:
10.1007/s10565-019-09478-4. [PMID: 31102011] - Susanne L T Cappendijk, Frank Johnson. Inhibitors of carbohydrate metabolism reduce undirected song production at doses that do not alter food intake in singly housed male zebra finches.
Behavioural brain research.
2005 Apr; 159(1):51-4. doi:
10.1016/j.bbr.2004.10.001. [PMID: 15794997] - F Désy, M G Latour, C Warren, J M Lavoie. Effects of portal injection of 2,5-anhydro-D-mannitol on pancreatic hormone responses to exercise in rats.
International journal of sports medicine.
1999 Jan; 20(1):17-22. doi:
10.1055/s-2007-971085. [PMID: 10090456] - J E Schneider. Effects of the fructose analog, 2,5-anhydro-D-mannitol, on food intake and estrous cyclicity in Syrian hamsters.
The American journal of physiology.
1997 Mar; 272(3 Pt 2):R935-9. doi:
10.1152/ajpregu.1997.272.3.r935. [PMID: 9087657] - I Villanueva, I S Racotta, R Racotta. Glucoprivation attenuates the hypophagia induced by epinephrine in mice.
Physiology & behavior.
1996 Nov; 60(5):1383-6. doi:
10.1016/s0031-9384(96)00216-8. [PMID: 8916199] - N E Rawson, P M Ulrich, M I Friedman. Fatty acid oxidation modulates the eating response to the fructose analogue 2,5-anhydro-D-mannitol.
The American journal of physiology.
1996 Jul; 271(1 Pt 2):R144-8. doi:
10.1152/ajpregu.1996.271.1.r144. [PMID: 8760215] - C R Park, L Benthem, R J Seeley, M I Friedman, C W Wilkinson, S C Woods. A comparison of the effects of food deprivation and 2,5-anhydro-D-mannitol on metabolism and ingestion.
The American journal of physiology.
1996 Jun; 270(6 Pt 2):R1250-6. doi:
10.1152/ajpregu.1996.270.6.r1250. [PMID: 8764291] - T Boswell, R D Richardson, R J Seeley, M Ramenofsky, J C Wingfield, M I Friedman, S C Woods. Regulation of food intake by metabolic fuels in white-crowned sparrows.
The American journal of physiology.
1995 Dec; 269(6 Pt 2):R1462-8. doi:
10.1152/ajpregu.1995.269.6.r1462. [PMID: 8594950] - B Ahrén, S Lindskog, G van Dijk, A J Scheurink, A B Steffens. Effects of GLP-1 and 2,5-anhydro-D-mannitol on insulin secretion and plasma glucose in mice.
Endocrine research.
1995 Aug; 21(3):583-94. doi:
10.1080/07435809509030475. [PMID: 7588428] - C R Park, R J Seeley, L Benthem, M I Friedman, S C Woods. Whole body energy expenditure and fuel oxidation after 2,5-anhydro-D-mannitol administration.
The American journal of physiology.
1995 Jan; 268(1 Pt 2):R299-302. doi:
10.1152/ajpregu.1995.268.1.r299. [PMID: 7840335] - N E Rawson, M I Friedman. Phosphate loading prevents the decrease in ATP and increase in food intake produced by 2,5-anhydro-D-mannitol.
The American journal of physiology.
1994 Jun; 266(6 Pt 2):R1792-6. doi:
10.1152/ajpregu.1994.266.6.r1792. [PMID: 8024030] - N E Rawson, H Blum, M D Osbakken, M I Friedman. Hepatic phosphate trapping, decreased ATP, and increased feeding after 2,5-anhydro-D-mannitol.
The American journal of physiology.
1994 Jan; 266(1 Pt 2):R112-7. doi:
10.1152/ajpregu.1994.266.1.r112. [PMID: 8304531] - N E Rowland. Effects of glucose and fat antimetabolites on norepinephrine turnover in rat hypothalamus and brainstem.
Brain research.
1992 Nov; 595(2):291-4. doi:
10.1016/0006-8993(92)91062-j. [PMID: 1361415] - T Sakata, M Kurokawa. Feeding modulation by pentose and hexose analogues.
The American journal of clinical nutrition.
1992 01; 55(1 Suppl):272S-277S. doi:
10.1093/ajcn/55.1.272s. [PMID: 1728839] - M Kurokawa, T Sakata, H Yoshimatsu, H Machidori. 2,5-Anhydro-D-mannitol: its unique central action on food intake and blood glucose in rats.
Brain research.
1991 Dec; 566(1-2):270-5. doi:
10.1016/0006-8993(91)91708-9. [PMID: 1814543] - M G Tordoff, N Rawson, M I Friedman. 2,5-anhydro-D-mannitol acts in liver to initiate feeding.
The American journal of physiology.
1991 Aug; 261(2 Pt 2):R283-8. doi:
10.1152/ajpregu.1991.261.2.r283. [PMID: 1908642] - M G Tordoff, R Rafka, M J DiNovi, M I Friedman. 2,5-anhydro-D-mannitol: a fructose analogue that increases food intake in rats.
The American journal of physiology.
1988 Jan; 254(1 Pt 2):R150-3. doi:
10.1152/ajpregu.1988.254.1.r150. [PMID: 3122594] - R L Hanson, R S Ho, J J Wiseberg, R Simpson, E S Younathan, J B Blair. Inhibition of gluconeogenesis and glycogenolysis by 2,5-anhydro-D-mannitol.
The Journal of biological chemistry.
1984 Jan; 259(1):218-23. doi:
. [PMID: 6423625] - S Marklund. Determination of plasma or serum haemoglobin by peroxidase activity employing 2,2'-azino-di-(3-ethyl-benzthiazolinsulphonate-6) as chromogen.
Scandinavian journal of clinical and laboratory investigation.
1978 Oct; 38(6):543-7. doi:
10.1080/00365517809108817. [PMID: 30165]
