2,4',5-Trichlorobiphenyl (BioDeep_00000173574)

   

human metabolite blood metabolite Industrial Pollutants


代谢物信息卡片


1,4-dichloro-2-(4-chlorophenyl)benzene

化学式: C12H7Cl3 (255.9613)
中文名称: 2,4,5-三氯联苯
谱图信息: 最多检出来源 Homo sapiens(general) 97.83%

分子结构信息

SMILES: C1=CC(=CC=C1C2=C(C=CC(=C2)Cl)Cl)Cl
InChI: InChI=1S/C12H7Cl3/c13-9-3-1-8(2-4-9)11-7-10(14)5-6-12(11)15/h1-7H

描述信息

D004785 - Environmental Pollutants > D011078 - Polychlorinated Biphenyls

同义名列表

6 个代谢物同义名

1,4-dichloro-2-(4-chlorophenyl)benzene; 2,5,4-Trichlorobiphenyl; 2,4,5-Trichlorobiphenyl; Delor-103; Delor 103; PCB 31



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Amani Achour, Abdelkader Derouiche, Mohamed Ridha Driss, Olfa Tebourbi. Organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) in adipose tissue of women from Grand Tunis and their association with demographic factors and dietary habits. Chemosphere. 2023 Oct; 338(?):139600. doi: 10.1016/j.chemosphere.2023.139600. [PMID: 37480958]
  • Cornelius Rimayi, Luke Chimuka. Organ-specific bioaccumulation of PCBs and PAHs in African sharptooth catfish (Clarias gariepinus) and common carp (Cyprinus carpio) from the Hartbeespoort Dam, South Africa. Environmental monitoring and assessment. 2019 Oct; 191(11):700. doi: 10.1007/s10661-019-7912-3. [PMID: 31667668]
  • Hana Horváthová, Katarína Lászlová, Katarína Dercová. Bioremediation of PCB-contaminated shallow river sediments: The efficacy of biodegradation using individual bacterial strains and their consortia. Chemosphere. 2018 Feb; 193(?):270-277. doi: 10.1016/j.chemosphere.2017.11.012. [PMID: 29141235]
  • Tomas Gichner, Petra Lovecka, Blanka Vrchotova. Genomic damage induced in tobacco plants by chlorobenzoic acids--metabolic products of polychlorinated biphenyls. Mutation research. 2008 Dec; 657(2):140-5. doi: 10.1016/j.mrgentox.2008.08.021. [PMID: 18835364]
  • J Rehulka, B Minarík. Effect of polychlorinated biphenyls (Delor 103) on haematological and enzyme parameters of the rainbow trout Oncorhynchus mykiss. Diseases of aquatic organisms. 2004 Nov; 62(1-2):147-53. doi: 10.3354/dao062147. [PMID: 15648841]
  • Guangming Zhang, Inez Hua. The impact of particulates on the aqueous sonication of bromobenzene. Chemosphere. 2002 Jan; 46(1):59-66. doi: 10.1016/s0045-6535(01)00079-0. [PMID: 11806533]
  • I Kalina, R J Srám, H Konecná, A Ondrusseková. Cytogenetic analysis of peripheral blood lymphocytes in workers occupationally exposed to polychlorinated biphenyls. Teratogenesis, carcinogenesis, and mutagenesis. 1991; 11(2):77-82. doi: 10.1002/tcm.1770110203. [PMID: 1686676]
  • A Piskac, J Ruprich, R Halouzka. [The effect of polyclorinated biphenyls in chickens: the effect of short-term administration of high doses of Delor 103 on the levels of thyroxine, triiodothyronine, sodium, potassium and calcium in the blood]. Veterinarni medicina. 1990 Apr; 35(4):237-46. doi: . [PMID: 2115702]
  • J Ruprich, A Piskac. [The effect of polychlorinated biphenyls (PCB) on chickens: the effect of long-term administration of medium doses of Delor 103 on the levels of thyroxine, triiodothyronine and total calcium in the blood serum]. Veterinarni medicina. 1990 Feb; 35(2):97-103. doi: NULL. [PMID: 2112802]
  • M Kujawa, R Macholz, J Schulze, W Schnaak. [Significance of gastrointestinal microflora for the metabolism of foreign compounds]. Die Nahrung. 1987; 31(5-6):619-24. doi: 10.1002/food.19870310581. [PMID: 2443851]
  • J E Bakke, A L Bergman, I Brandt, P Darnerud, C Struble. Metabolism of the mercapturic acid of 2,4',5-trichlorobiphenyl in rats and mice. Xenobiotica; the fate of foreign compounds in biological systems. 1983 Oct; 13(10):597-605. doi: 10.3109/00498258309052219. [PMID: 6424345]
  • J E Bakke, V J Feil, A Bergman. Metabolites of 2,4',5-trichlorobiphenyl in rats. Xenobiotica; the fate of foreign compounds in biological systems. 1983 Sep; 13(9):555-64. doi: 10.3109/00498258309052295. [PMID: 6419479]
  • J E Bakke, A L Bergman, G L Larsen. Metabolism of 2,4',5-trichlorobiphenyl by the mercapturic acid pathway. Science (New York, N.Y.). 1982 Aug; 217(4560):645-7. doi: 10.1126/science.6806905. [PMID: 6806905]
  • I Brandt, E Klasson-Wehler, J Rafter, A Bergman. Metabolism of 2,4',5-trichlorobiphenyl: tissue concentrations of methylsulphonyl-2,4',5-trichlorobiphenyl in germfree and conventional mice. Toxicology letters. 1982 Aug; 12(4):273-80. doi: 10.1016/0378-4274(82)90251-x. [PMID: 6814019]
  • A Bergman, A Biessmann, I Brandt, J Rafter. Metabolism of 2,4',5-trichlorobiphenyl: role of the intestinal microflora in the formation of bronchial-seeking methyl sulphone metabolites in mice. Chemico-biological interactions. 1982 Jun; 40(2):123-31. doi: 10.1016/0009-2797(82)90094-1. [PMID: 6805965]
  • P Török, L W Weber. Distribution of polychlorobiphenyls in pregnant mice and fetuses on various days of gestation. Archives of environmental contamination and toxicology. 1981; 10(3):289-96. doi: 10.1007/bf01055630. [PMID: 6789782]
  • T Fukushima. [Monoamine oxidase (XXXVI). Characteristics of benzylamine oxidase in the dog serum]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 1975 Jul; 71(5):457-62. doi: . [PMID: 280]