2,4-Thiazolidinedione (BioDeep_00000173560)
human metabolite blood metabolite
代谢物信息卡片
2,4-Thiazolidinedione potassium
化学式: C3H3NO2S (116.9884498)
中文名称: 2,4-噻唑烷二酮
谱图信息:
最多检出来源 Homo sapiens(blood) 33.04%
分子结构信息
SMILES: C1C(=O)NC(=O)S1
InChI: InChI=1S/C3H3NO2S/c5-2-1-7-3(6)4-2/h1H2,(H,4,5,6)
描述信息
D007004 - Hypoglycemic Agents
同义名列表
数据库引用编号
8 个数据库交叉引用编号
- ChEBI: CHEBI:50992
- PubChem: 5437
- HMDB: HMDB0245469
- DrugBank: DB11898
- ChEMBL: CHEMBL85398
- chemspider: 5242
- CAS: 2295-31-0
- RefMet: Thiazolidinedione
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Xinyi Zhang, Yuan Gao, Keyun Tang, Zongyu Li, Alexandra A Halberstam, Liqun Zhou, Rachel J Perry. Thiazolidinedione enhances the efficacy of anti-PD-1 monoclonal antibody in murine melanoma.
American journal of physiology. Endocrinology and metabolism.
2024 Mar; 326(3):E341-E350. doi:
10.1152/ajpendo.00346.2023. [PMID: 38294697] - Lim Shern Kwok, Shim Siang Yian, Layla Qasim Ismael, Yvonne Tee Get Bee, Gam Lay Harn, Khoo Boon Yin. Vimentin protein is a factor for decreasing breast cancer cell proliferation co-culture with human bone marrow-derived mesenchymal stem cells pre-treated with thiazolidinedione solutions.
Molecular biology reports.
2024 Feb; 51(1):317. doi:
10.1007/s11033-024-09269-z. [PMID: 38381204] - Rozh Q Ameen, Zahra A Amin, Hiwa O Ahmad, Diler D Ghafur, Melodya G Toma, Nyan Sabah, Muhammad Fakhir, Gardoon Abdulla. Gastroprotective effect of rhodanine and 2,4-thiazolidinediones scaffolds in rat stomachs by contribution of anti-apoptotic (BCL-2) and tumor suppressor (P53) proteins.
Scientific reports.
2024 01; 14(1):1699. doi:
10.1038/s41598-024-51446-4. [PMID: 38242960] - Yuanbo Qi, Mingyao Hu, Yang Qiu, Luyu Zhang, Yongchuang Yan, Yi Feng, Chenghao Feng, Xinyue Hou, Zhigang Wang, Di Zhang, Jie Zhao. Mitoglitazone ameliorates renal ischemia/reperfusion injury by inhibiting ferroptosis via targeting mitoNEET.
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2023 Mar; ?(?):116440. doi:
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Diabetes & metabolic syndrome.
2023 Jan; 17(1):102703. doi:
10.1016/j.dsx.2022.102703. [PMID: 36634469] - Chris E Shannon, Mukundan Ragavan, Juan Pablo Palavicini, Marcel Fourcaudot, Terry M Bakewell, Ivan A Valdez, Iriscilla Ayala, Eunsook S Jin, Muniswamy Madesh, Xianlin Han, Matthew E Merritt, Luke Norton. Insulin resistance is mechanistically linked to hepatic mitochondrial remodeling in non-alcoholic fatty liver disease.
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2021 03; 45(?):101154. doi:
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2020 Nov; 87(4):416-423. doi:
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Diabetes research and clinical practice.
2010 Jul; 89(1):52-7. doi:
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Wiener klinische Wochenschrift.
2010 Apr; 122(7-8):198-202. doi:
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Nephrology (Carlton, Vic.).
2010 Feb; 15(1):75-83. doi:
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Phytomedicine : international journal of phytotherapy and phytopharmacology.
2009 Dec; 16(12):1119-26. doi:
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Hepatology (Baltimore, Md.).
2009 Oct; 50(4):1087-93. doi:
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Diabetes, obesity & metabolism.
2009 May; 11 Suppl 2(?):18-26. doi:
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Journal of the American Society of Nephrology : JASN.
2009 Apr; 20(4):721-9. doi:
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European journal of medicinal chemistry.
2008 Nov; 43(11):2412-7. doi:
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Translational research : the journal of laboratory and clinical medicine.
2008 Jun; 151(6):309-14. doi:
10.1016/j.trsl.2008.04.003. [PMID: 18514142] - Yasuhiro Hamada, Masafumi Fukagawa. [Relationship between lipid and glucose metabolism and bone mineral metabolism : pleiotropic effects of therapeutic agents for diabetes and hyperlipidemia].
Clinical calcium.
2008 May; 18(5):671-6. doi:
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American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.
2008 Mar; 65(6):521-31. doi:
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Nephrology (Carlton, Vic.).
2008 Feb; 13(1):53-7. doi:
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American journal of nephrology.
2008; 28(5):823-30. doi:
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Annual review of biochemistry.
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Diabetes, obesity & metabolism.
2008 Jan; 10(1):82-90. doi:
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The Journal of biological chemistry.
2007 Oct; 282(41):29946-57. doi:
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The Journal of biological chemistry.
2007 Aug; 282(32):23591-602. doi:
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Journal of dairy science.
2007 Aug; 90(8):3660-70. doi:
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Annals of internal medicine.
2007 Apr; 146(7):477-85. doi:
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American journal of physiology. Renal physiology.
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Diabetes, obesity & metabolism.
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The Journal of clinical endocrinology and metabolism.
2007 Feb; 92(2):666-72. doi:
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Periodontology 2000.
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Journal of lipid research.
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Bone.
2006 Oct; 39(4):796-806. doi:
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Diabetologia.
2006 Sep; 49(9):2217-8. doi:
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Experimental gerontology.
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The American journal of medicine.
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Proceedings of the National Academy of Sciences of the United States of America.
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Acta pharmacologica Sinica.
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The Journal of nutrition.
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The Journal of pharmacology and experimental therapeutics.
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The Journal of biological chemistry.
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Diabetes, obesity & metabolism.
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