2,2'-Azobis(2-amidinopropane) (BioDeep_00000173467)
human metabolite blood metabolite Volatile Flavor Compounds
代谢物信息卡片
2-[2-(1-carbamimidoyl-1-methylethyl)diazen-1-yl]-2-methylpropanimidamide
化学式: C8H18N6 (198.15928680000002)
中文名称: 2,2'-偶氮双-2-甲基丙酰胺
谱图信息:
最多检出来源 Homo sapiens(blood) 56.62%
分子结构信息
SMILES: CC(C)(C(=N)N)N=NC(C)(C)C(=N)N
InChI: InChI=1S/C8H18N6/c1-7(2,5(9)10)13-14-8(3,4)6(11)12/h1-4H3,(H3,9,10)(H3,11,12)
描述信息
D009676 - Noxae > D009153 - Mutagens
D009676 - Noxae > D016877 - Oxidants
同义名列表
14 个代谢物同义名
2-[2-(1-carbamimidoyl-1-methylethyl)diazen-1-yl]-2-methylpropanimidamide; 2,2-Azobis(2-methylpropaneimidamide) dihydrochloride; 2,2-Azobis(2-amidinopropane) monohydrochloride; 2,2-Azobis(2-amidinopropane) dihydrochloride; 2,2-Azobis(2-amidinopropane)dihydrochloride; 2,2-Azobis(2-amidinopropane) acetate; 2,2-Azobis(2-methylpropionamidine); 2,2-Azo-bis(2-amidinopropane); 2,2-Azobis(2-amidinopropane); AMPH CPD; ABAPH; AAPH; ABAP; 2,2'-Azobis-2-methylpropanimidamide
数据库引用编号
7 个数据库交叉引用编号
- ChEBI: CHEBI:94003
- PubChem: 1969
- HMDB: HMDB0245347
- ChEMBL: CHEMBL1623736
- ChEMBL: CHEMBL1619966
- chemspider: 21493940
- CAS: 13217-66-8
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Yuan Zheng, Xueyang Ren, Xiaodan Qi, Ruolan Song, Chongjun Zhao, Jiamu Ma, Xianxian Li, Qingyue Deng, Yingyu He, Lingmei Kong, Liyan Qian, Feng Zhang, Mingxia Li, Mengyu Sun, Wei Liu, Haibin Liu, Gaimei She. Bao Yuan decoction alleviates fatigue by restraining inflammation and oxidative stress via the AMPK/CRY2/PER1 signaling pathway.
Journal of ethnopharmacology.
2024 Jun; 328(?):118058. doi:
10.1016/j.jep.2024.118058. [PMID: 38513778] - Rener Mateus Francisco Duarte, Serena Mares Malta, Fernanda Naves Araújo do Prado Mascarenhas, Vinicius Prado Bittar, Ana Luiza Borges, Renata Roland Teixeira, Renata Graciele Zanon, Carlos Ueira Vieira, Foued Salmen Espindola. Chronic exposure to 2,2'-azobis-2-amidinopropane that induces intestinal damage and oxidative stress in larvae of Drosophila melanogaster.
Environmental toxicology and pharmacology.
2024 Mar; 106(?):104388. doi:
10.1016/j.etap.2024.104388. [PMID: 38355029] - Kittipot Sirichaiwetchakoon, Griangsak Eumkeb. Free radical scavenging and anti-isolated human LDL oxidation activities of Butea superba Roxb. extract.
BMC complementary medicine and therapies.
2024 Feb; 24(1):75. doi:
10.1186/s12906-024-04373-w. [PMID: 38310207] - Allisson Benatti Justino, Vinicius Prado Bittar, Ana Luiza Borges, María Sol Peña Carrillo, Simone Sommerfeld, Iasmin Aparecida Cunha Araújo, Neide Maria da Silva, Belchiolina Beatriz Fonseca, Anielle Christine Almeida, Foued Salmen Espindola. Curcumin-functionalized gold nanoparticles attenuate AAPH-induced acute cardiotoxicity via reduction of lipid peroxidation and modulation of antioxidant parameters in a chicken embryo model.
International journal of pharmaceutics.
2023 Oct; 646(?):123486. doi:
10.1016/j.ijpharm.2023.123486. [PMID: 37802259] - Mingjuan Shen, Xi Yang, Zhenxing Wang, Xiaomei Sha, Xuechun Zhang, Jian Sun. The Impact of AAPH-Induced Oxidation on the Functional and Structural Properties, and Proteomics of Arachin.
Molecules (Basel, Switzerland).
2023 Aug; 28(17):. doi:
10.3390/molecules28176277. [PMID: 37687106] - Hyo-Geun Lee, D P Nagahawatta, Fengqi Yang, H H A C K Jayawardhana, N M Liyanage, Dae-Sung Lee, Jeong Min Lee, Mi-Jin Yim, Seok-Chun Ko, Ji-Yul Kim, Hyesuck An, Kyunghwa Baek, You-Jin Jeon, Hyun-Soo Kim. Antioxidant potential of hydrolysate-derived seahorse (Hippocampus abdominalis) peptide: Protective effects against AAPH-induced oxidative damage in vitro and in vivo.
Food chemistry.
2023 May; 407(?):135130. doi:
10.1016/j.foodchem.2022.135130. [PMID: 36527945] - Weixi Li, Rongping Huang, Shaocong Han, Xiyou Li, Haibiao Gong, Qiongyi Zhang, Changyu Yan, Yifang Li, Rongrong He. Potential of Tamarind Shell Extract against Oxidative Stress In Vivo and In Vitro.
Molecules (Basel, Switzerland).
2023 Feb; 28(4):. doi:
10.3390/molecules28041885. [PMID: 36838870] - Lei Wang, Thilina U Jayawardena, Jimin Hyun, Kaiqiang Wang, Xiaoting Fu, Jiachao Xu, Xin Gao, Youngjin Park, You-Jin Jeon. Antioxidant and anti-photoaging effects of a fucoidan isolated from Turbinaria ornata.
International journal of biological macromolecules.
2023 Jan; 225(?):1021-1027. doi:
10.1016/j.ijbiomac.2022.11.164. [PMID: 36410533] - Qinhua Zheng, Weijian Tan, Xiaolin Feng, Kexin Feng, Wenting Zhong, Caiyu Liao, Yuntong Liu, Shangjian Li, Wenzhong Hu. Protective Effect of Flavonoids from Mulberry Leaf on AAPH-Induced Oxidative Damage in Sheep Erythrocytes.
Molecules (Basel, Switzerland).
2022 Nov; 27(21):. doi:
10.3390/molecules27217625. [PMID: 36364452] - Consuelo B Correa Sierra, Luis M Schang. On the Sensitivity of the Virion Envelope to Lipid Peroxidation.
Microbiology spectrum.
2022 10; 10(5):e0300922. doi:
10.1128/spectrum.03009-22. [PMID: 36125312] - Pakawit Lerksaipheng, Kittiphong Paiboonsukwong, Pimtip Sanvarinda, Rataya Leuchapudiporn, Ken-Ichi Yamada, Noppawan Phumala Morales. Kinetics of lipid radical formation in lipoproteins from β-thalassemia: Implication of cholesteryl esters and α-tocopherol.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2022 Oct; 154(?):113624. doi:
10.1016/j.biopha.2022.113624. [PMID: 36057220] - Xiaoxi Gao, Yuhong Zhang, Guangqing Mu, Yunpeng Xu, Xinmiao Wang, Yanfeng Tuo, Fang Qian. Protecting Effect of Bacillus coagulans T242 on HT-29 Cells Against AAPH-Induced Oxidative Damage.
Probiotics and antimicrobial proteins.
2022 08; 14(4):741-750. doi:
10.1007/s12602-022-09917-5. [PMID: 35501534] - Hongwei Cao, Rulian Sun, Junru Shi, Mengyao Li, Xiao Guan, Jing Liu, Kai Huang, Yu Zhang. Effect of ultrasonic on the structure and quality characteristics of quinoa protein oxidation aggregates.
Ultrasonics sonochemistry.
2021 Sep; 77(?):105685. doi:
10.1016/j.ultsonch.2021.105685. [PMID: 34364069] - Dong Yu-Hao, Chen Chun, Huang Qiang, Fu Xiong. Study on a novel spherical polysaccharide from Fructus Mori with good antioxidant activity.
Carbohydrate polymers.
2021 Mar; 256(?):117516. doi:
10.1016/j.carbpol.2020.117516. [PMID: 33483037] - Jawhar Fakhfakh, Khaled Athmouni, Hanen Mallek-Fakhfakh, Habib Ayedi, Noureddine Allouche. Polysaccharide from Lycium arabicum: Structural Features, in Vitro Antioxidant Activities and Protective Effect against Oxidative Damage in Human Erythrocytes.
Chemistry & biodiversity.
2020 Dec; 17(12):e2000614. doi:
10.1002/cbdv.202000614. [PMID: 33084194] - Laura Fási, Ahmed Dhahir Latif, István Zupkó, Sándor Lévai, Miklós Dékány, Zoltán Béni, Árpád Könczöl, György Tibor Balogh, Attila Hunyadi. AAPH or Peroxynitrite-Induced Biorelevant Oxidation of Methyl Caffeate Yields a Potent Antitumor Metabolite.
Biomolecules.
2020 11; 10(11):. doi:
10.3390/biom10111537. [PMID: 33187226] - Sara Fernandes, Catarina Ribeiro, Fátima Paiva-Martins, Cristina Catarino, Alice Santos-Silva. Protective effect of olive oil polyphenol phase II sulfate conjugates on erythrocyte oxidative-induced hemolysis.
Food & function.
2020 Oct; 11(10):8670-8679. doi:
10.1039/d0fo01690j. [PMID: 32939526] - Jing-Jing Zhang, Zong-Cai Tu, Hui Wang, Yue-Ming Hu, Peng-Cheng Du, Yi-Peng Yang. Mechanism of the effect of 2, 2'-azobis (2-amidinopropane) dihydrochloride simulated lipid oxidation on the IgG/IgE binding ability of ovalbumin.
Food chemistry.
2020 Oct; 327(?):127037. doi:
10.1016/j.foodchem.2020.127037. [PMID: 32446030] - Yu-Lin Dai, Yun-Fei Jiang, Yu-An Lu, Min-Cheol Kang, You-Jin Jeon. Fucoidan from acid-processed Hizikia fusiforme attenuates oxidative damage and regulate apoptosis.
International journal of biological macromolecules.
2020 Oct; 160(?):390-397. doi:
10.1016/j.ijbiomac.2020.05.143. [PMID: 32446896] - Katarzyna Naparło, Mirosław Soszyński, Grzegorz Bartosz, Izabela Sadowska-Bartosz. Comparison of Antioxidants: The Limited Correlation between Various Assays of Antioxidant Activity.
Molecules (Basel, Switzerland).
2020 Jul; 25(14):. doi:
10.3390/molecules25143244. [PMID: 32708839] - Xueting Wang, Jing Yu, Binlong Ji, Yuling Yang. Decursin inhibits the oxidation of low-density lipoprotein and protects human aortic endothelial cells against oxidative damage.
Cellular and molecular biology (Noisy-le-Grand, France).
2020 Jun; 66(3):155-158. doi:
. [PMID: 32538763] - Tiancheng Ma, Jia Sun, Xiangkun Li, Yukun Ma, Lei Liu, Lina Guo, Qi Liu, Yu Sun. Optimization of extraction for Anemarrhena asphodeloides Bge. using silica gel-based vortex-homogenized matrix solid-phase dispersion and rapid identification of antioxidant substances.
Journal of separation science.
2020 Jun; 43(11):2180-2192. doi:
10.1002/jssc.202000101. [PMID: 32133730] - Jae-Young Oh, Eun-A Kim, Sang In Kang, Hye-Won Yang, Bomi Ryu, Lei Wang, Jung-Suck Lee, You-Jin Jeon. Protective Effects of Fucoidan Isolated from Celluclast-Assisted Extract of Undaria pinnatifida Sporophylls against AAPH-Induced Oxidative Stress In Vitro and In Vivo Zebrafish Model.
Molecules (Basel, Switzerland).
2020 May; 25(10):. doi:
10.3390/molecules25102361. [PMID: 32438702] - Anissa Algara Beni, Renata Fritzsche Rodrigues, Lisiane Conte, Isabella Ferreira Costa, Érika Aparecida Delalibera, Miguel Roehrs, Cristine Rampelotto, Tatiana Emanuelli, Sabrina Somacal. Dietary supplementation with annatto food-coloring extracts increases the resistance of human erythrocytes to hemolysis.
Nutrition research (New York, N.Y.).
2020 04; 76(?):71-81. doi:
10.1016/j.nutres.2020.02.003. [PMID: 32217378] - Huifang Zhang, Rui Liu, Qun Lu. Separation and Characterization of Phenolamines and Flavonoids from Rape Bee Pollen, and Comparison of Their Antioxidant Activities and Protective Effects Against Oxidative Stress.
Molecules (Basel, Switzerland).
2020 Mar; 25(6):. doi:
10.3390/molecules25061264. [PMID: 32168811] - Long-Fang Tu, Ling-Fang Cao, Yue-Hong Zhang, Yu-Lin Guo, Yang-Fan Zhou, Wei-Qi Lu, Tian-Ze Zhang, Tao Zhang, Gao-Xiao Zhang, Hiroshi Kurihara, Yi-Fang Li, Rong-Rong He. Sirt3-dependent deacetylation of COX-1 counteracts oxidative stress-induced cell apoptosis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2019 12; 33(12):14118-14128. doi:
10.1096/fj.201900708r. [PMID: 31647884] - Arokiadhas Iswarya, Mahalingam Anjugam, Sivakumar Shanthini, Baskaralingam Vaseeharan. Protective activity of beta-1, 3-glucan binding protein against AAPH induced oxidative stress in Saccharomyces cerevisiae.
International journal of biological macromolecules.
2019 Oct; 138(?):890-902. doi:
10.1016/j.ijbiomac.2019.07.130. [PMID: 31344413] - Alicia Jiménez-Almarza, Daniel Diez-Iriepa, Mourad Chioua, Beatriz Chamorro, Isabel Iriepa, Ricardo Martínez-Murillo, Dimitra Hadjipavlou-Litina, María Jesús Oset-Gasque, José Marco-Contelles. Synthesis, neuroprotective and antioxidant capacity of PBN-related indanonitrones.
Bioorganic chemistry.
2019 05; 86(?):445-451. doi:
10.1016/j.bioorg.2019.01.071. [PMID: 30771691] - Kervin O Evans, David L Compton, Sanghoon Kim, Michael Appell. Charged phospholipid effects on AAPH oxidation assay as determined using liposomes.
Chemistry and physics of lipids.
2019 05; 220(?):49-56. doi:
10.1016/j.chemphyslip.2019.02.004. [PMID: 30796887] - Xiaoli Zhao, Qiang Zhao, Hongbing Chen, Hua Xiong. Distribution and effects of natural selenium in soybean proteins and its protective role in soybean β-conglycinin (7S globulins) under AAPH-induced oxidative stress.
Food chemistry.
2019 Jan; 272(?):201-209. doi:
10.1016/j.foodchem.2018.08.039. [PMID: 30309533] - Ping Wu, Xiaofeng Meng, Huade Zheng, Qin Zeng, Tianfeng Chen, Wen Wang, Xia Zhang, Jianyu Su. Kaempferol Attenuates ROS-Induced Hemolysis and the Molecular Mechanism of Its Induction of Apoptosis on Bladder Cancer.
Molecules (Basel, Switzerland).
2018 Oct; 23(10):. doi:
10.3390/molecules23102592. [PMID: 30309003] - María Teresa Ariza, Tamara Y Forbes-Hernández, Patricia Reboredo-Rodríguez, Sadia Afrin, Massimiliano Gasparrini, Lucía Cervantes, Carmen Soria, Elsa Martínez-Ferri, Maurizio Battino, Francesca Giampieri. Strawberry and Achenes Hydroalcoholic Extracts and Their Digested Fractions Efficiently Counteract the AAPH-Induced Oxidative Damage in HepG2 Cells.
International journal of molecular sciences.
2018 Jul; 19(8):. doi:
10.3390/ijms19082180. [PMID: 30049933] - Anna A Torkova, Ksenia V Lisitskaya, Ivan S Filimonov, Olga A Glazunova, Galina S Kachalova, Vladimir N Golubev, Tatyana V Fedorova. Physicochemical and functional properties of Cucurbita maxima pumpkin pectin and commercial citrus and apple pectins: A comparative evaluation.
PloS one.
2018; 13(9):e0204261. doi:
10.1371/journal.pone.0204261. [PMID: 30235297] - Jihong Wu, Jiaying Huo, Mingquan Huang, Mouming Zhao, Xuelian Luo, Baoguo Sun. Structural Characterization of a Tetrapeptide from Sesame Flavor-Type Baijiu and Its Preventive Effects against AAPH-Induced Oxidative Stress in HepG2 Cells.
Journal of agricultural and food chemistry.
2017 Dec; 65(48):10495-10504. doi:
10.1021/acs.jafc.7b04815. [PMID: 29115123] - Larissa Socrier, Marie Rosselin, Fanny Choteau, Grégory Durand, Sandrine Morandat. Cholesterol-nitrone conjugates as protective agents against lipid oxidation: A model membrane study.
Biochimica et biophysica acta. Biomembranes.
2017 Dec; 1859(12):2495-2504. doi:
10.1016/j.bbamem.2017.09.026. [PMID: 28982534] - Hsin-Ling Yang, Mallikarjuna Korivi, Ming-Kuem Lin, Hebron Chun-Wei Chang, Chi-Rei Wu, Meng-Shiou Lee, William Tzu-Liang Chen, You-Cheng Hseu. Antihemolytic and antioxidant properties of pearl powder against 2,2'-azobis(2-amidinopropane) dihydrochloride-induced hemolysis and oxidative damage to erythrocyte membrane lipids and proteins.
Journal of food and drug analysis.
2017 Oct; 25(4):898-907. doi:
10.1016/j.jfda.2016.10.007. [PMID: 28987367] - E Belcastro, W Wu, I Fries-Raeth, A Corti, A Pompella, P Leroy, I Lartaud, C Gaucher. Oxidative stress enhances and modulates protein S-nitrosation in smooth muscle cells exposed to S-nitrosoglutathione.
Nitric oxide : biology and chemistry.
2017 Sep; 69(?):10-21. doi:
10.1016/j.niox.2017.07.004. [PMID: 28743484] - Hyun Joo Lee, Hang Yeon Jeong, Mi Rim Jin, Hyoung Jae Lee, Jeong-Yong Cho, Jae-Hak Moon. Metabolism and antioxidant effect of malaxinic acid and its corresponding aglycone in rat blood plasma.
Free radical biology & medicine.
2017 09; 110(?):399-407. doi:
10.1016/j.freeradbiomed.2017.06.020. [PMID: 28669626] - Soorya Parathodi Illam, Arunaksharan Narayanankutty, Achuthan C Raghavamenon. Polyphenols of virgin coconut oil prevent pro-oxidant mediated cell death.
Toxicology mechanisms and methods.
2017 Jul; 27(6):442-450. doi:
10.1080/15376516.2017.1320458. [PMID: 28412883] - E Dorta, A Aspée, E Pino, L González, E Lissi, C López-Alarcón. Controversial alkoxyl and peroxyl radical scavenging activity of the tryptophan metabolite 3-hydroxy-anthranilic acid.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2017 Jun; 90(?):332-338. doi:
10.1016/j.biopha.2017.03.082. [PMID: 28376401] - Silvina Bartesaghi, Daniel Herrera, Débora M Martinez, Ariel Petruk, Verónica Demicheli, Madia Trujillo, Marcelo A Martí, Darío A Estrín, Rafael Radi. Tyrosine oxidation and nitration in transmembrane peptides is connected to lipid peroxidation.
Archives of biochemistry and biophysics.
2017 05; 622(?):9-25. doi:
10.1016/j.abb.2017.04.006. [PMID: 28412156] - Xiu-Min Chen, Andrew R Tait, David D Kitts. Flavonoid composition of orange peel and its association with antioxidant and anti-inflammatory activities.
Food chemistry.
2017 Mar; 218(?):15-21. doi:
10.1016/j.foodchem.2016.09.016. [PMID: 27719891] - Yin-Ran Hu, Hang Ma, Zong-Yao Zou, Kai He, Yu-Bo Xiao, Yue Wang, Min Feng, Xiao-Li Ye, Xue-Gang Li. Activation of Akt and JNK/Nrf2/NQO1 pathway contributes to the protective effect of coptisine against AAPH-induced oxidative stress.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2017 Jan; 85(?):313-322. doi:
10.1016/j.biopha.2016.11.031. [PMID: 27903425] - Dong-Sung Lee, Seung-Hong Lee, You-Jin Jeon, Sun Hee Cheong. Antioxidant Effects of Short-Neck Clam (Tapes philippinarum) Water Extract Containing Taurine Against AAPH-Induced Oxidative Stress in Zebrafish Embryos.
Advances in experimental medicine and biology.
2017 ; 975 Pt 2(?):1035-1046. doi:
10.1007/978-94-024-1079-2_82. [PMID: 28849520] - Oren Rom, Nina Volkova, Sukhendu Nandi, Raz Jelinek, Michael Aviram. Pomegranate Juice Polyphenols Induce Macrophage Death via Apoptosis as Opposed to Necrosis Induced by Free Radical Generation: A Central Role for Oxidative Stress.
Journal of cardiovascular pharmacology.
2016 Aug; 68(2):106-14. doi:
10.1097/fjc.0000000000000391. [PMID: 27010808] - Ling Li, Tao Huang, Cheng Tian, Yubo Xiao, Shuming Kou, Xia Zhou, Shanshan Liu, Xiaoli Ye, Xuegang Li. The defensive effect of phellodendrine against AAPH-induced oxidative stress through regulating the AKT/NF-κB pathway in zebrafish embryos.
Life sciences.
2016 Jul; 157(?):97-106. doi:
10.1016/j.lfs.2016.05.032. [PMID: 27234894] - Eric Keven Silva, Giovani L Zabot, Cinthia B B Cazarin, Mário R Maróstica, M Angela A Meireles. Biopolymer-prebiotic carbohydrate blends and their effects on the retention of bioactive compounds and maintenance of antioxidant activity.
Carbohydrate polymers.
2016 Jun; 144(?):149-58. doi:
10.1016/j.carbpol.2016.02.045. [PMID: 27083804] - Sasidharan Salini, Menon Kunnathully Divya, Thomas Chubicka, Nair Meera, Devanand P Fulzele, Achuthan C Ragavamenon, Thekkekara Devassy Babu. Protective effect of Scutellaria species on AAPH-induced oxidative damage in human erythrocyte.
Journal of basic and clinical physiology and pharmacology.
2016 Jun; 27(4):403-9. doi:
10.1515/jbcpp-2015-0081. [PMID: 26669246] - Ju-Hyeong Kim, Tae-Sik Park, Seung-Hwan Yang, Joo-Won Suh, Soon-Mi Shim. Microbial bioconversion and processing methods enhance the phenolic acid and flavonoids and the radical scavenging capacity of Smilax china L. leaf.
Journal of the science of food and agriculture.
2016 Feb; 96(3):878-85. doi:
10.1002/jsfa.7160. [PMID: 25754764] - Karine Santos De Bona, Gabriela Bonfanti, Paula Eliete Rodrigues Bitencourt, Thainan Paz da Silva, Raphaela Maleski Borges, Aline Boligon, Aline Pigatto, Margareth Lynde Athayde, Maria Beatriz Moretto. Protective effect of gallic acid and Syzygium cumini extract against oxidative stress-induced cellular injury in human lymphocytes.
Drug and chemical toxicology.
2016; 39(3):256-63. doi:
10.3109/01480545.2015.1084631. [PMID: 26364973] - A M Popov, A N Osipov, E A Korepanova, O N Krivoshapko, Yu P Shtoda, A A Klimovich. [Study of Antioxidant and Membranotropic Activities of Quinazoline Alkaloid Tryptanthrin Using Different Model Systems].
Biofizika.
2015 Jul; 60(4):700-7. doi:
". [PMID: 26394469] - Sakina Razack, Kandikattu Hemanth Kumar, Ilaiyaraja Nallamuthu, Mahadeva Naika, Farhath Khanum. Antioxidant, Biomolecule Oxidation Protective Activities of Nardostachys jatamansi DC and Its Phytochemical Analysis by RP-HPLC and GC-MS.
Antioxidants (Basel, Switzerland).
2015 Mar; 4(1):185-203. doi:
10.3390/antiox4010185. [PMID: 26785345] - Sun Hee Cheong, Jin-Woo Hwang, Seung-Hong Lee, Yon-Suk Kim, Eun-Kyung Kim, Sang-Hoon Lee, Dong-June Park, Chang-Bum Ahn, Byong Tae Jeon, Sang-Ho Moon, Pyo-Jam Park, Si Heung Sung. Protective Effect of Mussel (Mytilus Coruscus) Extract Containing Taurine Against AAPH-Induced Oxidative Stress in Zebrafish Model.
Advances in experimental medicine and biology.
2015; 803(?):807-18. doi:
10.1007/978-3-319-15126-7_65. [PMID: 25833547] - Neha Qasim, Riaz Mahmood. Diminution of Oxidative Damage to Human Erythrocytes and Lymphocytes by Creatine: Possible Role of Creatine in Blood.
PloS one.
2015; 10(11):e0141975. doi:
10.1371/journal.pone.0141975. [PMID: 26555819] - B Narotzki, A Z Reznick, T Mitki, D Aizenbud, Y Levy. Green tea drinking improves erythrocytes and saliva oxidative status in the elderly.
Advances in experimental medicine and biology.
2015; 832(?):25-33. doi:
10.1007/5584_2014_8. [PMID: 25300686] - V N Titov, N N Sazhina. Evaluation of serum antioxidant activity in patients with liver pathology by the chemiluminescent method.
Bulletin of experimental biology and medicine.
2014 Dec; 158(2):287-9. doi:
10.1007/s10517-014-2742-3. [PMID: 25432290] - Wenzhen Liao, Zhengxiang Ning, Ling Ma, Xueru Yin, Qingyi Wei, Erdong Yuan, Jiguo Yang, Jiaoyan Ren. Recrystallization of dihydromyricetin from Ampelopsis grossedentata and its anti-oxidant activity evaluation.
Rejuvenation research.
2014 Oct; 17(5):422-9. doi:
10.1089/rej.2014.1555. [PMID: 24835723] - Gabriela Bonfanti, Karine Santos De Bona, Leidiane de Lucca, Leticia Jantsch, Aline Schirmer Pigatto, Aline A Boligon, Margareth L Athayde, Maria Beatriz Moretto, Thissiane de Lima Gonçalves. Delta-ALA-D inhibitory potential and protective action of Syzygium jambos and Solanum guaraniticum leaf extracts on oxidatively stressed erythrocytes.
Redox report : communications in free radical research.
2014 Sep; 19(5):206-13. doi:
10.1179/1351000214y.0000000092. [PMID: 24725132] - Hui-Fang Chiu, Jen-Kun Cheng, Pu-Hua Lin, Jung-Chen Chang, I-Ming Chen, Ching-I Lin, Wei-Pin Chang, Chia-Hsien Lin. A mechanistic study on urine retention in d-amphetamine addicts.
The Chinese journal of physiology.
2014 Aug; 57(4):171-81. doi:
10.4077/cjp.2014.bac198. [PMID: 25246058] - Wenzhen Liao, Zhengxiang Ning, Luying Chen, Qingyi Wei, Erdong Yuan, Jiguo Yang, Jiaoyan Ren. Intracellular antioxidant detoxifying effects of diosmetin on 2,2-azobis(2-amidinopropane) dihydrochloride (AAPH)-induced oxidative stress through inhibition of reactive oxygen species generation.
Journal of agricultural and food chemistry.
2014 Aug; 62(34):8648-54. doi:
10.1021/jf502359x. [PMID: 25075433] - M Praschberger, M Hermann, J Wanner, L Jirovetz, M Exner, S Kapiotis, B M K Gmeiner, H Laggner. The uremic toxin indoxyl sulfate acts as a pro- or antioxidant on LDL oxidation.
Free radical research.
2014 Jun; 48(6):641-8. doi:
10.3109/10715762.2014.898294. [PMID: 24568219] - Jessy Mariam, S Sivakami, D C Kothari, P M Dongre. Bioactivity of albumins bound to silver nanoparticles.
The protein journal.
2014 Jun; 33(3):258-66. doi:
10.1007/s10930-014-9553-2. [PMID: 24715529] - Chiaki Abe, Yoshihiro Uto, Ayaka Kawasaki, Chiho Noguchi, Ryo Tanaka, Toru Yoshitomi, Yukio Nagasaki, Yoshio Endo, Hitoshi Hori. Evaluation of the in vivo antioxidative activity of redox nanoparticles by using a developing chicken egg as an alternative animal model.
Journal of controlled release : official journal of the Controlled Release Society.
2014 May; 182(?):67-72. doi:
10.1016/j.jconrel.2014.03.015. [PMID: 24637467] - Elisabete Maciel, Bruno M Neves, Deolinda Santinha, Ana Reis, Pedro Domingues, M Teresa Cruz, Andrew R Pitt, Corinne M Spickett, M Rosário M Domingues. Detection of phosphatidylserine with a modified polar head group in human keratinocytes exposed to the radical generator AAPH.
Archives of biochemistry and biophysics.
2014 Apr; 548(?):38-45. doi:
10.1016/j.abb.2014.02.002. [PMID: 24560783] - Ilaria Peluso, Luca Romanelli, Silvana Spagnuolo, Husseen Manafikhi, Maura Palmery. Serum depletion, multidrug resistance and fluorescent probes: methodological implications in free radicals evaluation.
Journal of immunological methods.
2014 Mar; 405(?):178-80. doi:
10.1016/j.jim.2013.12.009. [PMID: 24389320] - Eun-A Kim, Seung-Hong Lee, Chang-ik Ko, Seon-Heui Cha, Min-Cheol Kang, Sung-Myung Kang, Seok-Chun Ko, Won-Woo Lee, Ju-Young Ko, Ji-Hyeok Lee, Nalae Kang, Jae-Young Oh, Ginnae Ahn, Young Heun Jee, You-Jin Jeon. Protective effect of fucoidan against AAPH-induced oxidative stress in zebrafish model.
Carbohydrate polymers.
2014 Feb; 102(?):185-91. doi:
10.1016/j.carbpol.2013.11.022. [PMID: 24507271] - Jingfei Zhang, Xiang Hou, Hussain Ahmad, Hao Zhang, Lili Zhang, Tian Wang. Assessment of free radicals scavenging activity of seven natural pigments and protective effects in AAPH-challenged chicken erythrocytes.
Food chemistry.
2014 Feb; 145(?):57-65. doi:
10.1016/j.foodchem.2013.08.025. [PMID: 24128449] - E O Omarova, Y N Antonenko. Inhibition of oxidative hemolysis in erythrocytes by mitochondria-targeted antioxidants of SkQ series.
Biochemistry. Biokhimiia.
2014 Feb; 79(2):139-45. doi:
10.1134/s0006297914020072. [PMID: 24794729] - N P Damascena, M T S Souza, A F Almeida, R S Cunha, N P Damascena, R L Curvello, A C B Lima, E C V Almeida, C C S Santos, A S Dias, M S Paixão, L M A Souza, L J Quintans Júnior, C S Estevam, B S Araujo. Antioxidant and orofacial anti-nociceptive activities of the stem bark aqueous extract of Anadenanthera colubrina (Velloso) Brenan (Fabaceae).
Natural product research.
2014; 28(10):753-6. doi:
10.1080/14786419.2013.877902. [PMID: 24438027] - Ju-Young Ko, Eun-A Kim, Ji-Hyeok Lee, Min-Cheol Kang, Jung-Suck Lee, Jin-Soo Kim, Won-Kyo Jung, You-Jin Jeon. Protective effect of aquacultured flounder fish-derived peptide against oxidative stress in zebrafish.
Fish & shellfish immunology.
2014 Jan; 36(1):320-3. doi:
10.1016/j.fsi.2013.11.018. [PMID: 24333583] - Xiang Hou, Jingfei Zhang, Hussain Ahmad, Hao Zhang, Ziwei Xu, Tian Wang. Evaluation of antioxidant activities of ampelopsin and its protective effect in lipopolysaccharide-induced oxidative stress piglets.
PloS one.
2014; 9(9):e108314. doi:
10.1371/journal.pone.0108314. [PMID: 25268121] - Min-Cheol Kang, Seo Young Kim, Yoon Taek Kim, Eun-A Kim, Seung-Hong Lee, Seok-Chun Ko, W A J P Wijesinghe, Kalpa W Samarakoon, Young-Sun Kim, Jin Hun Cho, Hyeang-Su Jang, You-Jin Jeon. In vitro and in vivo antioxidant activities of polysaccharide purified from aloe vera (Aloe barbadensis) gel.
Carbohydrate polymers.
2014 Jan; 99(?):365-71. doi:
10.1016/j.carbpol.2013.07.091. [PMID: 24274519] - K Vanaja, M A Wahl, L Bukarica, H Heinle. Liposomes as carriers of the lipid soluble antioxidant resveratrol: evaluation of amelioration of oxidative stress by additional antioxidant vitamin.
Life sciences.
2013 Dec; 93(24):917-23. doi:
10.1016/j.lfs.2013.10.019. [PMID: 24177602] - J Courraud, C Charnay, J P Cristol, J Berger, S Avallone. In vitro lipid peroxidation of intestinal bile salt-based nanoemulsions: potential role of antioxidants.
Free radical research.
2013 Dec; 47(12):1076-87. doi:
10.3109/10715762.2013.853877. [PMID: 24128050] - Yonathan Asikin, Makoto Takahashi, Takashi Mishima, Masami Mizu, Kensaku Takara, Koji Wada. Antioxidant activity of sugarcane molasses against 2,2'-azobis(2-amidinopropane) dihydrochloride-induced peroxyl radicals.
Food chemistry.
2013 Nov; 141(1):466-72. doi:
10.1016/j.foodchem.2013.03.045. [PMID: 23768381] - K S Fernandes, A H M Silva, S A Mendanha, K R Rezende, A Alonso. Antioxidant effect of 4-nerolidylcatechol and α-tocopherol in erythrocyte ghost membranes and phospholipid bilayers.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.
2013 Sep; 46(9):780-8. doi:
10.1590/1414-431x20132940. [PMID: 24068194] - K J Senthil Kumar, Hsin-Ling Yang, Yu-Cheng Tsai, Pin-Chun Hung, Show-Huei Chang, Heng-Wei Lo, Pei-Chun Shen, Ssu-Ching Chen, Hui-Min Wang, Sheng-Yang Wang, Chih-Wei Chou, You-Cheng Hseu. Lucidone protects human skin keratinocytes against free radical-induced oxidative damage and inflammation through the up-regulation of HO-1/Nrf2 antioxidant genes and down-regulation of NF-κB signaling pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2013 Sep; 59(?):55-66. doi:
10.1016/j.fct.2013.04.055. [PMID: 23712098] - Min-Cheol Kang, Seon Heui Cha, W A J P Wijesinghe, Sung-Myung Kang, Seung-Hong Lee, Eun-A Kim, Choon Bok Song, You-Jin Jeon. Protective effect of marine algae phlorotannins against AAPH-induced oxidative stress in zebrafish embryo.
Food chemistry.
2013 Jun; 138(2-3):950-5. doi:
10.1016/j.foodchem.2012.11.005. [PMID: 23411200] - Ilaria Peluso, Gaspare Adorno, Anna Raguzzini, Lourdes Urban, Andrea Ghiselli, Mauro Serafini. A new flow cytometry method to measure oxidative status: the Peroxidation of Leukocytes Index Ratio (PLIR).
Journal of immunological methods.
2013 Apr; 390(1-2):113-20. doi:
10.1016/j.jim.2013.02.005. [PMID: 23454245] - Fan Li, Jian-Hong Wu, Qing-Hua Wang, Yuan-Lan Shu, Chun-Wai Wan, Chi-On Chan, Daniel Kam-Wah Mok, Shun-Wan Chan. Gui-ling-gao, a traditional Chinese functional food, prevents oxidative stress-induced apoptosis in H9c2 cardiomyocytes.
Food & function.
2013 Apr; 4(5):745-53. doi:
10.1039/c3fo30182f. [PMID: 23467630] - Rangaswamy Lakshminarayana, Gorusupudi Aruna, Upparahalli V Sathisha, Shylaja M Dharmesh, Vallikannan Baskaran. Structural elucidation of possible lutein oxidation products mediated through peroxyl radical inducer 2,2'-Azobis (2-methylpropionamidine) dihydrochloride: antioxidant and cytotoxic influence of oxidized lutein in HeLa cells.
Chemico-biological interactions.
2013 Apr; 203(2):448-55. doi:
10.1016/j.cbi.2013.03.006. [PMID: 23518229] - Shawn N Watson, Natasha Wright, Petra M Hermann, Willem C Wildering. Phospholipase A₂: the key to reversing long-term memory impairment in a gastropod model of aging.
Neurobiology of aging.
2013 Feb; 34(2):610-20. doi:
10.1016/j.neurobiolaging.2012.02.028. [PMID: 22459601] - Xiaoxia Li, Xiaowen Shi, Yong Jin, Fuyuan Ding, Yumin Du. Controllable antioxidative xylan-chitosan Maillard reaction products used for lipid food storage.
Carbohydrate polymers.
2013 Jan; 91(1):428-33. doi:
10.1016/j.carbpol.2012.08.052. [PMID: 23044153] - Yanliang Lin, Jinglei Liu, Yibo Hu, Xin Song, Yueran Zhao. An antioxidant exopolysaccharide devoid of pro-oxidant activity produced by the soil bacterium Bordetella sp. B4.
Bioresource technology.
2012 Nov; 124(?):245-51. doi:
10.1016/j.biortech.2012.05.145. [PMID: 22989652] - Heshmatollah Alinezhad, Mahboobeh Zare, Seyed Fazel Nabavi, Alireza Naqinezhad, Seyed Mohammad Nabavi. Antioxidant, antihemolytic, and inhibitory activities of endemic Primula heterochroma against Fe2+-induced lipid peroxidation and oxidative stress in rat brain in vitro.
Pharmaceutical biology.
2012 Nov; 50(11):1391-6. doi:
10.3109/13880209.2012.676050. [PMID: 22900682] - Jia-Yu Wang, Jeremy Marks, Ka Yee C Lee. Nature of interactions between PEO-PPO-PEO triblock copolymers and lipid membranes: (I) effect of polymer hydrophobicity on its ability to protect liposomes from peroxidation.
Biomacromolecules.
2012 Sep; 13(9):2616-23. doi:
10.1021/bm300847x. [PMID: 22808900] - Peter A C McPherson, Amanda Bole, Kenneth A Cruz, Ian S Young, Jane McEneny. A curvilinear approach to the kinetic analysis of linoleate peroxidation in aqueous liposomes by 2,2'azobis(2-amidoinopropane) dihydrochloride.
Chemistry and physics of lipids.
2012 Sep; 165(6):682-8. doi:
10.1016/j.chemphyslip.2012.07.004. [PMID: 22841574] - Yusei Kashima, Mitsuo Miyazawa. Synthesis and biological evaluation of bergenin analogues as mushroom tyrosinase inhibitors.
Archives of pharmacal research.
2012 Sep; 35(9):1533-41. doi:
10.1007/s12272-012-0903-3. [PMID: 23054709] - Jihed Boubaker, Mohammed Ben Sghaier, Ines Skandrani, Kamel Ghedira, Leila Chekir-Ghedira. Isorhamnetin 3-O-robinobioside from Nitraria retusa leaves enhance antioxidant and antigenotoxic activity in human chronic myelogenous leukemia cell line K562.
BMC complementary and alternative medicine.
2012 Aug; 12(?):135. doi:
10.1186/1472-6882-12-135. [PMID: 22913434] - Cui Wang, Yan Chen, Meili Hu, Jingna Ding, Cunji Xu, Ruijun Wang. In vitro antioxidant activities of the polysaccharides from Tricholoma lobayense.
International journal of biological macromolecules.
2012 Apr; 50(3):534-9. doi:
10.1016/j.ijbiomac.2012.01.005. [PMID: 22305884] - Sara Elsøe, Josefin Ahnström, Christina Christoffersen, Andrew N Hoofnagle, Peter Plomgaard, Jay W Heinecke, Christoph J Binder, Harry Björkbacka, Björn Dahlbäck, Lars B Nielsen. Apolipoprotein M binds oxidized phospholipids and increases the antioxidant effect of HDL.
Atherosclerosis.
2012 Mar; 221(1):91-7. doi:
10.1016/j.atherosclerosis.2011.11.031. [PMID: 22204862] - Joseph A Laszlo, Kervin O Evans, David L Compton, Michael Appell. Dihydrolipoyl dioleoylglycerol antioxidant capacity in phospholipid vesicles.
Chemistry and physics of lipids.
2012 Feb; 165(2):160-8. doi:
10.1016/j.chemphyslip.2011.12.003. [PMID: 22197684] - Anat Elmann, Alona Telerman, Sharon Mordechay, Hilla Erlank, Rivka Ofir. Antioxidant and astroprotective effects of a Pulicaria incisa infusion.
Oxidative medicine and cellular longevity.
2012; 2012(?):157598. doi:
10.1155/2012/157598. [PMID: 23320126] - Ki Sung Kang, Hyun Young Kim, Hye Hyun Yoo, Xiang Lan Piao, Jungyeob Ham, Hyun Ok Yang, Jeong Hill Park. Protective effect of ginseng sapogenins against 2,2'-azobis (1-aminopropane) dihydrochloride (AAPH)-induced LLC-PK₁ cell damage.
Bioorganic & medicinal chemistry letters.
2012 Jan; 22(1):634-7. doi:
10.1016/j.bmcl.2011.10.063. [PMID: 22113113] - Muhammad Zubair, Farooq Anwar, Muhammad Ashraf, Md Kamal Uddin. Characterization of high-value bioactives in some selected varieties of Pakistani Rice (Oryza sativa L.).
International journal of molecular sciences.
2012; 13(4):4608-4622. doi:
10.3390/ijms13044608. [PMID: 22605998] - Shawn N Watson, Mark A Nelson, Willem C Wildering. Redox agents modulate neuronal activity and reproduce physiological aspects of neuronal aging.
Neurobiology of aging.
2012 Jan; 33(1):149-61. doi:
10.1016/j.neurobiolaging.2010.01.017. [PMID: 20153084] - Laura Zambonin, Cristiana Caliceti, Francesco Vieceli Dalla Sega, Diana Fiorentini, Silvana Hrelia, Laura Landi, Cecilia Prata. Dietary phenolic acids act as effective antioxidants in membrane models and in cultured cells, exhibiting proapoptotic effects in leukaemia cells.
Oxidative medicine and cellular longevity.
2012; 2012(?):839298. doi:
10.1155/2012/839298. [PMID: 22792417] - Monika A Olszewska. Variation in the phenolic content and in vitro antioxidant activity of Sorbus aucuparia leaf extracts during vegetation.
Acta poloniae pharmaceutica.
2011 Nov; 68(6):937-44. doi:
. [PMID: 22125960] - Monika A Olszewska. In vitro antioxidant activity and total phenolic content of the inflorescences, leaves and fruits of Sorbus torminalis (L.) Crantz.
Acta poloniae pharmaceutica.
2011 Nov; 68(6):945-53. doi:
. [PMID: 22125961]