2-Methyl-2-phenoxypropanoic acid (BioDeep_00000173359)
human metabolite blood metabolite
代谢物信息卡片
化学式: C10H12O3 (180.0786402)
中文名称: 2-甲基-2-苯氧基丙酸
谱图信息:
最多检出来源 Mus musculus(blood) 50%
分子结构信息
SMILES: CC(C)(C(=O)O)OC1=CC=CC=C1
InChI: InChI=1S/C10H12O3/c1-10(2,9(11)12)13-8-6-4-3-5-7-8/h3-7H,1-2H3,(H,11,12)
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- S Da Silva, L G Cal-Pereyra, A Benech, J Acosta-Dibarrat, M J Martin, M C Abreu, S Perini, J R González-Montaña. Evaluation of a fibrate, specific stimulant of PPARα, as a therapeutic alternative to the treatment of clinical ovine pregnancy toxaemia.
Journal of veterinary pharmacology and therapeutics.
2016 Oct; 39(5):497-503. doi:
10.1111/jvp.12304. [PMID: 26969801] - Minako Karahashi, Hiroto Fukuhara, Miki Hoshina, Takeshi Sakamoto, Tohru Yamazaki, Atsushi Mitsumoto, Yoichi Kawashima, Naomi Kudo. A simple and sensitive method for the determination of fibric acids in the liver by liquid chromatography.
Biological & pharmaceutical bulletin.
2014; 37(1):105-12. doi:
10.1248/bpb.b13-00631. [PMID: 24389487] - Annalisa Rizzo, Carlo Gazza, Maddalena Mutinati, Salvatore Desantis, Sara Zizza, Giovanni D'Onghia, Gianfranco D'Onghia, Marianna Pantaleo, Raffaele L Sciorsci. Effects of mefepronic acid (2-phenoxy-2-methyl propionic acid) on hepatic metabolism and reproductive parameters in postpartum dairy cows.
Endocrine, metabolic & immune disorders drug targets.
2014; 14(2):113-22. doi:
10.2174/1871530314666140223184913. [PMID: 24568187] - Jin Wi, Jong-Youn Kim, Sungha Park, Seok-Min Kang, Yangsoo Jang, Namsik Chung, Won-Heum Shim, Seung-Yun Cho, Sang-Hak Lee. Optimal pharmacologic approach to patients with hypertriglyceridemia and low high-density lipoprotein-cholesterol: randomized comparison of fenofibrate 160 mg and niacin 1500 mg.
Atherosclerosis.
2010 Nov; 213(1):235-40. doi:
10.1016/j.atherosclerosis.2010.08.068. [PMID: 20855072] - Ilan Goldenberg, Michal Benderly, Uri Goldbourt. Update on the use of fibrates: focus on bezafibrate.
Vascular health and risk management.
2008; 4(1):131-41. doi:
10.2147/vhrm.2008.04.01.131. [PMID: 18629356] - Anne Marie Api. Evaluation of the dermal subchronic toxicity of phenoxyethyl isobutyrate in the rat.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2004 Feb; 42(2):307-11. doi:
10.1016/j.fct.2003.09.005. [PMID: 14667475] - Xiaoqi Chen, Dale J Kempf, Lin Li, Hing L Sham, Sudthida Vasavanonda, Norman E Wideburg, Ayda Saldivar, Kennan C Marsh, Edith McDonald, Daniel W Norbeck. Synthesis and SAR studies of potent HIV protease inhibitors containing novel dimethylphenoxyl acetates as P2 ligands.
Bioorganic & medicinal chemistry letters.
2003 Nov; 13(21):3657-60. doi:
10.1016/j.bmcl.2003.08.043. [PMID: 14552751]