2-Hydroxy-4-methylthiobutyric acid (BioDeep_00000173295)
human metabolite blood metabolite
代谢物信息卡片
化学式: C5H10O2S (134.0401)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCC(C(=O)S)O
InChI: InChI=1S/C5H10O2S/c1-2-3-4(6)5(7)8/h4,6H,2-3H2,1H3,(H,7,8)
描述信息
同义名列表
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- Quirine Swennen, Pierre-André Geraert, Yves Mercier, Nadia Everaert, Anneleen Stinckens, Hilke Willemsen, Yue Li, Eddy Decuypere, Johan Buyse. Effects of dietary protein content and 2-hydroxy-4-methylthiobutanoic acid or DL-methionine supplementation on performance and oxidative status of broiler chickens.
The British journal of nutrition.
2011 Dec; 106(12):1845-54. doi:
10.1017/s0007114511002558. [PMID: 21736775] - H Willemsen, Q Swennen, N Everaert, P-A Geraert, Y Mercier, A Stinckens, E Decuypere, J Buyse. Effects of dietary supplementation of methionine and its hydroxy analog DL-2-hydroxy-4-methylthiobutanoic acid on growth performance, plasma hormone levels, and the redox status of broiler chickens exposed to high temperatures.
Poultry science.
2011 Oct; 90(10):2311-20. doi:
10.3382/ps.2011-01353. [PMID: 21934015] - Xue Tang, Yonglan Yang, Yonghui Shi, Guowei Le. Comparative in vivo antioxidant capacity of DL-2-hydroxy-4-methylthiobutanoic acid (HMTBA) and DL-methionine in male mice fed a high-fat diet.
Journal of the science of food and agriculture.
2011 Sep; 91(12):2166-72. doi:
10.1002/jsfa.4434. [PMID: 21567412] - Zhengfeng Fang, Feiruo Huang, Jie Luo, Hongkui Wei, Libao Ma, Siwen Jiang, Jian Peng. Effects of dl-2-hydroxy-4-methylthiobutyrate on the first-pass intestinal metabolism of dietary methionine and its extra-intestinal availability.
The British journal of nutrition.
2010 Mar; 103(5):643-51. doi:
10.1017/s0007114509992169. [PMID: 20064283] - Zhengfeng Fang, Hefeng Luo, Hongkui Wei, Feiruo Huang, Zhili Qi, Siwen Jiang, Jian Peng. Methionine metabolism in piglets Fed DL-methionine or its hydroxy analogue was affected by distribution of enzymes oxidizing these sources to keto-methionine.
Journal of agricultural and food chemistry.
2010 Feb; 58(3):2008-14. doi:
10.1021/jf903317x. [PMID: 20073466] - M Xie, S S Hou, W Huang, H P Fan. Effect of excess methionine and methionine hydroxy analogue on growth performance and plasma homocysteine of growing Pekin ducks.
Poultry science.
2007 Sep; 86(9):1995-9. doi:
10.1093/ps/86.9.1995. [PMID: 17704389] - S Wang, W G Bottje, Z Song, K Beers, M Vazques-Añon, J J Dibner. Uptake of DL-2-hydroxy-4-methylthio-butanoic acid (DL-HMB) in the broiler liver in vivo.
Poultry science.
2001 Nov; 80(11):1619-24. doi:
10.1093/ps/80.11.1619. [PMID: 11732679] - Z Song, K Beers, J J Dibner, M Vázquez-Añón, R McNew, W Bottje. The hepatic extraction of plasma free amino acids and response to hepatic portal venous infusion of methionine sources in anesthetized SCWL males (Gallus domesticus).
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.
2001 Sep; 130(2):237-50. doi:
10.1016/s1096-4959(01)00430-4. [PMID: 11544094]
