2-Furamide (BioDeep_00000173283)

   

human metabolite blood metabolite Volatile Flavor Compounds


代谢物信息卡片


2,2-Dichloro-4-hydroxy-N-methylacetanilide 2-furoate

化学式: C5H5NO2 (111.032027)
中文名称: 2-糠酰胺, 2-呋喃酰胺
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=COC(=C1)C(=O)N
InChI: InChI=1S/C5H5NO2/c6-5(7)4-2-1-3-8-4/h1-3H,(H2,6,7)

描述信息

D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents

同义名列表

9 个代谢物同义名

2,2-Dichloro-4-hydroxy-N-methylacetanilide 2-furoate; furan-2-carboxamide; 2-Furancarboxamide; DILOXANIDE FUROATE; Entamide furoate; Diloxanide; 2-Furamide; Furamide; 2-Furamide



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • T Al-Qirim, G Shattat, G A Sheikha, K Sweidan, Y Al-Hiari, A Jarab. Synthesis of novel N-(4-benzoylphenyl)-2-furamide derivatives and their pharmacological evaluation as potent antihyperlipidemic agents in rats. Drug research. 2015 Mar; 65(3):158-63. doi: 10.1055/s-0034-1375646. [PMID: 24848001]
  • Mahmoud Mohamed Issa, R'afat Mahmoud Nejem, Alaa Mohamed Abu Shanab, Nahed Talab Shaat. Kinetic spectrophotometric H-point standard addition method for the simultaneous determination of diloxanide furoate and metronidazole in binary mixtures and biological fluids. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2013 Oct; 114(?):592-8. doi: 10.1016/j.saa.2013.05.062. [PMID: 23807049]
  • Tsukasa Fujishima, Shoichi Nishise, Masahiro Ichihara, Seiki Kobayashi, Tsutomu Takeuchi. Difficulties in the treatment of intestinal amoebiasis in mentally disabled individuals at a rehabilitation institution for the intellectually impaired in Japan. Chemotherapy. 2010; 56(4):348-52. doi: 10.1159/000320187. [PMID: 20720419]
  • H Qureshi, A Ali, R Baqai, W Ahmed. Efficacy of a combined diloxanide furoate-metronidazole preparation in the treatment of amoebiasis and giardiasis. The Journal of international medical research. 1997 May; 25(3):167-70. doi: 10.1177/030006059702500307. [PMID: 9178149]
  • M Sengupta, O Sengupta. Correlation of biological activity (therapeutic and toxic) with solvochromic properties of metronidazole, emetine hydrochloride and diloxanide furoate. Indian journal of biochemistry & biophysics. 1995 Oct; 32(5):302-7. doi: . [PMID: 8713754]
  • T Jelinek, M Ziegler, T Löscher. [Gnathostomiasis after a stay in Thailand]. Deutsche medizinische Wochenschrift (1946). 1994 Nov; 119(47):1618-22. doi: 10.1055/s-2008-1058879. [PMID: 7982372]
  • M Sengupta, H Dutta, D K Pal, A U De, C Sengupta. Correlation of phospholipid loss in goat whole blood with solvochromic properties of antiamebics like emetine, metronidazole and diloxanide furoate. Indian journal of experimental biology. 1993 Jan; 31(1):21-5. doi: . [PMID: 8500812]
  • J C Samuelson, A Burke, J M Courval. Susceptibility of an emetine-resistant mutant of Entamoeba histolytica to multiple drugs and to channel blockers. Antimicrobial agents and chemotherapy. 1992 Nov; 36(11):2392-7. doi: 10.1128/aac.36.11.2392. [PMID: 1283295]
  • A L Luaces, T Picó, A J Barrett. The ENZYMEBA test: detection of intestinal Entamoeba histolytica infection by immuno-enzymatic detection of histolysain. Parasitology. 1992 Oct; 105 ( Pt 2)(?):203-5. doi: 10.1017/s0031182000074114. [PMID: 1454418]
  • P D Marsden. Treatment of cyst passers. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 1992 Sep; 15(3):559. doi: 10.1093/clind/15.3.559. [PMID: 1520814]
  • C V Smith, H Hughes, J R Mitchell. Free radicals in vivo. Covalent binding to lipids. Molecular pharmacology. 1984 Jul; 26(1):112-6. doi: . [PMID: 6749128]
  • B Reichlin, K Gyr, M Giger, A L Blum. [Diagnosis of intestinal amebiasis]. Schweizerische medizinische Wochenschrift. 1981 Feb; 111(7):210-4. doi: NULL. [PMID: 6111842]
  • D BOTERO. TREATMENT OF ACUTE AND CHRONIC INTESTINAL AMOEBIASIS WITH ENTAMIDE FUROATE. Transactions of the Royal Society of Tropical Medicine and Hygiene. 1964 Sep; 58(?):419-21. doi: 10.1016/0035-9203(64)90088-4. [PMID: 14206697]