2-Chloroacetanilide (BioDeep_00000173222)

   

human metabolite blood metabolite Volatile Flavor Compounds


代谢物信息卡片


2-chloro-N-phenylethanimidic acid

化学式: C8H8ClNO (169.02943879999998)
中文名称: 2-氯-N-苯基乙酰胺, 2-氯乙酰苯胺
谱图信息: 最多检出来源 Homo sapiens(blood) 0.33%

分子结构信息

SMILES: C1=CC=C(C=C1)NC(=O)CCl
InChI: InChI=1S/C8H8ClNO/c9-6-8(11)10-7-4-2-1-3-5-7/h1-5H,6H2,(H,10,11)

描述信息

同义名列表

4 个代谢物同义名

2-chloro-N-phenylethanimidic acid; 2-Chloro-N-phenylethanimidate; 2-chloroacetanilide; 2-Chloroacetanilide



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

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  • Hubert Sytykiewicz. Expression patterns of glutathione transferase gene (GstI) in maize seedlings under juglone-induced oxidative stress. International journal of molecular sciences. 2011; 12(11):7982-95. doi: 10.3390/ijms12117982. [PMID: 22174645]
  • Lei Ma, Jiangli Dong, Yongsheng Jin, Mingliang Chen, Xiaoye Shen, Tao Wang. RMDAP: a versatile, ready-to-use toolbox for multigene genetic transformation. PloS one. 2011; 6(5):e19883. doi: 10.1371/journal.pone.0019883. [PMID: 21603635]
  • Maria Fernandez-Alvarez, J Pablo Lamas, Maria Garcia-Chao, Carmen Garcia-Jares, Maria Llompart, Marta Lores, Thierry Dagnac. Monitoring of pesticide residues in dairy cattle farms from NW Spain. Journal of environmental monitoring : JEM. 2010 Oct; 12(10):1864-75. doi: 10.1039/c0em00054j. [PMID: 20721413]
  • Kostantinos Benekos, Christos Kissoudis, Irini Nianiou-Obeidat, Nikolaos Labrou, Panagiotis Madesis, Mary Kalamaki, Antonis Makris, Athanasios Tsaftaris. Overexpression of a specific soybean GmGSTU4 isoenzyme improves diphenyl ether and chloroacetanilide herbicide tolerance of transgenic tobacco plants. Journal of biotechnology. 2010 Oct; 150(1):195-201. doi: 10.1016/j.jbiotec.2010.07.011. [PMID: 20638428]
  • Rosemary Castorina, Asa Bradman, Laura Fenster, Dana Boyd Barr, Roberto Bravo, Michelle G Vedar, Martha E Harnly, Thomas E McKone, Ellen A Eisen, Brenda Eskenazi. Comparison of current-use pesticide and other toxicant urinary metabolite levels among pregnant women in the CHAMACOS cohort and NHANES. Environmental health perspectives. 2010 Jun; 118(6):856-63. doi: 10.1289/ehp.0901568. [PMID: 20129873]
  • David Weisman, Merianne Alkio, Adán Colón-Carmona. Transcriptional responses to polycyclic aromatic hydrocarbon-induced stress in Arabidopsis thaliana reveal the involvement of hormone and defense signaling pathways. BMC plant biology. 2010 Apr; 10(?):59. doi: 10.1186/1471-2229-10-59. [PMID: 20377843]
  • Malay Das, Jay R Reichman, Georg Haberer, Gerhard Welzl, Felipe F Aceituno, Michael T Mader, Lidia S Watrud, Thomas G Pfleeger, Rodrigo A Gutiérrez, Anton R Schäffner, David M Olszyk. A composite transcriptional signature differentiates responses towards closely related herbicides in Arabidopsis thaliana and Brassica napus. Plant molecular biology. 2010 Mar; 72(4-5):545-56. doi: 10.1007/s11103-009-9590-y. [PMID: 20043233]
  • Haitao Bian, Jingwen Chen, Xiyun Cai, Ping Liu, Ying Wang, Liping Huang, Xianliang Qiao, Ce Hao. Dechlorination of chloroacetanilide herbicides by plant growth regulator sodium bisulfite. Water research. 2009 Aug; 43(14):3566-74. doi: 10.1016/j.watres.2009.05.002. [PMID: 19520412]
  • M S Butchiram, K S Tilak, P W Raju. Studies on histopathological changes in the gill, liver and kidney of Channa punctatus (Bloch) exposed to Alachlor. Journal of environmental biology. 2009 Mar; 30(2):303-6. doi: . [PMID: 20121036]
  • Melissa Brazier-Hicks, Kathryn M Evans, Oliver D Cunningham, David R W Hodgson, Patrick G Steel, Robert Edwards. Catabolism of glutathione conjugates in Arabidopsis thaliana. Role in metabolic reactivation of the herbicide safener fenclorim. The Journal of biological chemistry. 2008 Jul; 283(30):21102-12. doi: 10.1074/jbc.m801998200. [PMID: 18522943]
  • Dana B Barr, Cynthia J Hines, Anders O Olsson, James A Deddens, Roberto Bravo, Cynthia A F Striley, Jessica Norrgran, Larry L Needham. Identification of human urinary metabolites of acetochlor in exposed herbicide applicators by high-performance liquid chromatography-tandem mass spectrometry. Journal of exposure science & environmental epidemiology. 2007 Sep; 17(6):559-66. doi: 10.1038/sj.jes.7500583. [PMID: 17534384]
  • Hyun-Young Cho, Kwang-Hoon Kong. Study on the biochemical characterization of herbicide detoxification enzyme, glutathione S-transferase. BioFactors (Oxford, England). 2007; 30(4):281-7. doi: 10.1002/biof.5520300410. [PMID: 18607078]
  • Eliana Nutricati, Antonio Miceli, Federica Blando, Luigi De Bellis. Characterization of two Arabidopsis thaliana glutathione S-transferases. Plant cell reports. 2006 Sep; 25(9):997-1005. doi: 10.1007/s00299-006-0146-1. [PMID: 16538523]
  • Tyrone B Hayes, Paola Case, Sarah Chui, Duc Chung, Cathryn Haeffele, Kelly Haston, Melissa Lee, Vien Phoung Mai, Youssra Marjuoa, John Parker, Mable Tsui. Pesticide mixtures, endocrine disruption, and amphibian declines: are we underestimating the impact?. Environmental health perspectives. 2006 Apr; 114 Suppl 1(?):40-50. doi: 10.1289/ehp.8051. [PMID: 16818245]
  • Hiroyuki Kawahigashi, Sakiko Hirose, Hideo Ohkawa, Yasunobu Ohkawa. Phytoremediation of metolachlor by transgenic rice plants expressing human CYP2B6. Journal of agricultural and food chemistry. 2005 Nov; 53(23):9155-60. doi: 10.1021/jf0511143. [PMID: 16277416]
  • Margarita Karavangeli, Nikolaos E Labrou, Yannis D Clonis, Athanasios Tsaftaris. Development of transgenic tobacco plants overexpressing maize glutathione S-transferase I for chloroacetanilide herbicides phytoremediation. Biomolecular engineering. 2005 Oct; 22(4):121-8. doi: 10.1016/j.bioeng.2005.03.001. [PMID: 16085457]
  • Melissa P Mezzari, Katherine Walters, Marcela Jelínkova, Ming-Che Shih, Craig L Just, Jerald L Schnoor. Gene expression and microscopic analysis of Arabidopsis exposed to chloroacetanilide herbicides and explosive compounds. A phytoremediation approach. Plant physiology. 2005 Jun; 138(2):858-69. doi: 10.1104/pp.104.056168. [PMID: 15923336]
  • Daniele Del Buono, Luciano Scarponi, Roberto D'Amato. An analytical method for the simultaneous determination of butachlor and benoxacor in wheat and soil. Journal of agricultural and food chemistry. 2005 Jun; 53(11):4326-30. doi: 10.1021/jf050127d. [PMID: 15913290]
  • R E Biagini, J P Smith, D L Sammons, B A MacKenzie, C A F Striley, S K Robertson, J E Snawder. Development of a sensitivity enhanced multiplexed fluorescence covalent microbead immunosorbent assay (FCMIA) for the measurement of glyphosate, atrazine and metolachlor mercapturate in water and urine. Analytical and bioanalytical chemistry. 2004 Jun; 379(3):368-74. doi: 10.1007/s00216-004-2628-8. [PMID: 15118800]
  • Shana R Dalton, Richard T Miller, Sharon A Meyer. The herbicide metolachlor induces liver cytochrome P450s 2B1/2 and 3A1/2, but not thyroxine-uridine dinucleotide phosphate glucuronosyltransferase and associated thyroid gland activity. International journal of toxicology. 2003 Jul; 22(4):287-95. doi: 10.1080/10915810305121. [PMID: 12933323]
  • Ian Cummins, David O'Hagan, Istvan Jablonkai, David J Cole, Alain Hehn, Danièle Werck-Reichhart, Robert Edwards. Cloning, characterization and regulation of a family of phi class glutathione transferases from wheat. Plant molecular biology. 2003 Jun; 52(3):591-603. doi: 10.1023/a:1024858218804. [PMID: 12956529]
  • Ben P DeRidder, David P Dixon, Douglas J Beussman, Robert Edwards, Peter B Goldsbrough. Induction of glutathione S-transferases in Arabidopsis by herbicide safeners. Plant physiology. 2002 Nov; 130(3):1497-505. doi: 10.1104/pp.010066. [PMID: 12428014]
  • Aqel W Abu-Qare, Harry J Duncan. Herbicide safeners: uses, limitations, metabolism, and mechanisms of action. Chemosphere. 2002 Sep; 48(9):965-74. doi: 10.1016/s0045-6535(02)00185-6. [PMID: 12222792]
  • David P Dixon, Adrian Lapthorn, Robert Edwards. Plant glutathione transferases. Genome biology. 2002; 3(3):REVIEWS3004. doi: 10.1186/gb-2002-3-3-reviews3004. [PMID: 11897031]
  • G Gullner, T Kömives, H Rennenberg. Enhanced tolerance of transgenic poplar plants overexpressing gamma-glutamylcysteine synthetase towards chloroacetanilide herbicides. Journal of experimental botany. 2001 May; 52(358):971-9. doi: 10.1093/jexbot/52.358.971. [PMID: 11432914]
  • X Q Wang, W Seinen, W De Wolf. Biotransformation of monochloroanilines in guppy, Poecilia reticulata. Xenobiotica; the fate of foreign compounds in biological systems. 1994 Jan; 24(1):59-69. doi: 10.3109/00498259409043221. [PMID: 8165822]