2-Chloro-1,3,5-triazine (BioDeep_00000173212)
human metabolite blood metabolite
代谢物信息卡片
化学式: C3H2ClN3 (114.9937242)
中文名称: 2-氯-1,3,5-三嗪
谱图信息:
最多检出来源 Mus musculus(blood) 18.84%
分子结构信息
SMILES: C1=NC=NC(=N1)Cl
InChI: InChI=1S/C3H2ClN3/c4-3-6-1-5-2-7-3/h1-2H
数据库引用编号
5 个数据库交叉引用编号
- ChEBI: CHEBI:38074
- PubChem: 5215566
- HMDB: HMDB0245050
- chemspider: 4386194
- CAS: 6153-86-2
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Michelle Gatien Hotchkiss, Deborah S Best, Ralph L Cooper, Susan C Laws. Atrazine does not induce pica behavior at doses that increase hypothalamic-pituitary-adrenal axis activation and cause conditioned taste avoidance.
Neurotoxicology and teratology.
2012 May; 34(3):295-302. doi:
10.1016/j.ntt.2012.03.001
. [PMID: 22430068] - Lori A Cragin, James S Kesner, Annette M Bachand, Dana Boyd Barr, Juliana W Meadows, Edward F Krieg, John S Reif. Menstrual cycle characteristics and reproductive hormone levels in women exposed to atrazine in drinking water.
Environmental research.
2011 Nov; 111(8):1293-301. doi:
10.1016/j.envres.2011.09.009
. [PMID: 22000761] - James W Simpkins, James A Swenberg, Noel Weiss, David Brusick, J Charles Eldridge, James T Stevens, Robert J Handa, Russell C Hovey, Tony M Plant, Timothy P Pastoor, Charles B Breckenridge. Atrazine and breast cancer: a framework assessment of the toxicological and epidemiological evidence.
Toxicological sciences : an official journal of the Society of Toxicology.
2011 Oct; 123(2):441-59. doi:
10.1093/toxsci/kfr176
. [PMID: 21768606] - Zhoumeng Lin, Jeffrey W Fisher, Matthew K Ross, Nikolay M Filipov. A physiologically based pharmacokinetic model for atrazine and its main metabolites in the adult male C57BL/6 mouse.
Toxicology and applied pharmacology.
2011 Feb; 251(1):16-31. doi:
10.1016/j.taap.2010.11.009
. [PMID: 21094656] - Hossein Mehrani, Mostafa Ghanei, Jafar Aslani, Zahra Tabatabaei. Plasma proteomic profile of sulfur mustard exposed lung diseases patients using 2-dimensional gel electrophoresis.
Clinical proteomics.
2011 Jan; 8(1):2. doi:
10.1186/1559-0275-8-2
. [PMID: 21906349] - Walid D Fakhouri, Joseph L Nuñez, Frances Trail. Atrazine binds to the growth hormone-releasing hormone receptor and affects growth hormone gene expression.
Environmental health perspectives.
2010 Oct; 118(10):1400-5. doi:
10.1289/ehp.0900738
. [PMID: 20529762] - Leah M Zorrilla, Emily K Gibson, Tammy E Stoker. The effects of simazine, a chlorotriazine herbicide, on pubertal development in the female Wistar rat.
Reproductive toxicology (Elmsford, N.Y.).
2010 Jul; 29(4):393-400. doi:
10.1016/j.reprotox.2010.03.010
. [PMID: 20381603] - Susan C Laws, Michelle Hotchkiss, Janet Ferrell, Saro Jayaraman, Lesley Mills, Walker Modic, Nicole Tinfo, Melanie Fraites, Tammy Stoker, Ralph Cooper. Chlorotriazine herbicides and metabolites activate an ACTH-dependent release of corticosterone in male Wistar rats.
Toxicological sciences : an official journal of the Society of Toxicology.
2009 Nov; 112(1):78-87. doi:
10.1093/toxsci/kfp190
. [PMID: 19690231] - Ramiro Maravilla-Galván, Reyna Fierro, Humberto González-Márquez, Sandra Gómez-Arroyo, Irma Jiménez, Miguel Betancourt. Effects of atrazine and fenoxaprop-ethyl on capacitation and the acrosomal reaction in boar sperm.
International journal of toxicology.
2009 Jan; 28(1):24-32. doi:
10.1177/1091581809333138
. [PMID: 19482828] - Dana B Barr, Parinya Panuwet, Johnny V Nguyen, Simeon Udunka, Larry L Needham. Assessing exposure to atrazine and its metabolites using biomonitoring.
Environmental health perspectives.
2007 Oct; 115(10):1474-8. doi:
10.1289/ehp.10141
. [PMID: 17938738] - Hyun-Young Cho, Kwang-Hoon Kong. Study on the biochemical characterization of herbicide detoxification enzyme, glutathione S-transferase.
BioFactors (Oxford, England).
2007; 30(4):281-7. doi:
10.1002/biof.5520300410
. [PMID: 18607078] - H Jiang, C Adams. Treatability of chloro-s-triazines by conventional drinking water treatment technologies.
Water research.
2006 May; 40(8):1657-67. doi:
10.1016/j.watres.2006.02.013
. [PMID: 16631856] - Jill M Brzezicki, Melvin E Andersen, Brian K Cranmer, John D Tessari. Quantitative identification of atrazine and its chlorinated metabolites in plasma.
Journal of analytical toxicology.
2003 Nov; 27(8):569-73. doi:
10.1093/jat/27.8.569
. [PMID: 14670135] - Tami S McMullin, Jill M Brzezicki, Brian K Cranmer, John D Tessari, Melvin E Andersen. Pharmacokinetic modeling of disposition and time-course studies with [14C]atrazine.
Journal of toxicology and environmental health. Part A.
2003 May; 66(10):941-64. doi:
10.1080/15287390306454
. [PMID: 12825238] - Tammy E Stoker, D L Guidici, S C Laws, R L Cooper. The effects of atrazine metabolites on puberty and thyroid function in the male Wistar rat.
Toxicological sciences : an official journal of the Society of Toxicology.
2002 Jun; 67(2):198-206. doi:
10.1093/toxsci/67.2.198
. [PMID: 12011479]