2-Aminobenzothiazole (BioDeep_00000173174)
human metabolite blood metabolite Industrial Pollutants Volatile Flavor Compounds
代谢物信息卡片
化学式: C7H6N2S (150.0251676)
中文名称: 苯并[d]噻唑-2-胺, 2-氨基苯并噻唑
谱图信息:
最多检出来源 Homo sapiens(blood) 99.58%
分子结构信息
SMILES: C1=CC=C2C(=C1)N=C(S2)N
InChI: InChI=1S/C7H6N2S/c8-7-9-5-3-1-2-4-6(5)10-7/h1-4H,(H2,8,9)
数据库引用编号
8 个数据库交叉引用编号
- ChEBI: CHEBI:167751
- PubChem: 8706
- HMDB: HMDB0245009
- ChEMBL: CHEMBL329785
- chemspider: 8382
- CAS: 102337-98-4
- CAS: 84293-42-5
- CAS: 136-95-8
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Bence Szilágyi, Péter Kovács, György G Ferenczy, Anita Rácz, Krisztina Németh, Júlia Visy, Pál Szabó, Janez Ilas, György T Balogh, Katalin Monostory, István Vincze, Tamás Tábi, Éva Szökő, György M Keserű. Discovery of isatin and 1H-indazol-3-ol derivatives as d-amino acid oxidase (DAAO) inhibitors.
Bioorganic & medicinal chemistry.
2018 05; 26(8):1579-1587. doi:
10.1016/j.bmc.2018.02.004. [PMID: 29472125] - Nishikant Wase, Boqiang Tu, James W Allen, Paul N Black, Concetta C DiRusso. Identification and Metabolite Profiling of Chemical Activators of Lipid Accumulation in Green Algae.
Plant physiology.
2017 Aug; 174(4):2146-2165. doi:
10.1104/pp.17.00433. [PMID: 28652262] - Ella Meltzer-Mats, Gali Babai-Shani, Lily Pasternak, Neta Uritsky, Tamar Getter, Olga Viskind, Jürgen Eckel, Erol Cerasi, Hanoch Senderowitz, Shlomo Sasson, Arie Gruzman. Synthesis and mechanism of hypoglycemic activity of benzothiazole derivatives.
Journal of medicinal chemistry.
2013 Jul; 56(13):5335-50. doi:
10.1021/jm4001488. [PMID: 23750537] - Fan Zhang, Qiu-Yue Lin, Shi-Kun Li, Yu-Ling Zhao, Peng-Peng Wang, Miao-Miao Chen. Synthesis, interaction with DNA and bovine serum albumin of the transition metal complexes of demethylcantharate and 2-aminobenzothiazole.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2012 Dec; 98(?):436-43. doi:
10.1016/j.saa.2012.08.074. [PMID: 22995471] - Yajing Sun, Baoling Su, Qifei Xu, Rutao Liu. Insights into the binding of 2-aminobenzothiazole with human serum albumin (HSA): spectroscopic investigation and molecular modeling studies.
Applied spectroscopy.
2012 Jul; 66(7):791-7. doi:
10.1366/11-06524. [PMID: 22710149] - A Boscolo, J A Starr, V Sanchez, N Lunardi, M R DiGruccio, C Ori, A Erisir, P Trimmer, J Bennett, V Jevtovic-Todorovic. The abolishment of anesthesia-induced cognitive impairment by timely protection of mitochondria in the developing rat brain: the importance of free oxygen radicals and mitochondrial integrity.
Neurobiology of disease.
2012 Mar; 45(3):1031-41. doi:
10.1016/j.nbd.2011.12.022. [PMID: 22198380] - Eva-Maria Hametner, Klaus Seppi, Werner Poewe. Role and clinical utility of pramipexole extended release in the treatment of early Parkinson's disease.
Clinical interventions in aging.
2012; 7(?):83-8. doi:
10.2147/cia.s11829. [PMID: 22500116] - Michael E Bozik, James L Mather, William G Kramer, Valentin K Gribkoff, Evan W Ingersoll. Safety, tolerability, and pharmacokinetics of KNS-760704 (dexpramipexole) in healthy adult subjects.
Journal of clinical pharmacology.
2011 Aug; 51(8):1177-85. doi:
10.1177/0091270010379412. [PMID: 20959524] - J P Hubble, P Novak. Pramipexole: a nonergot dopamine agonist as drug therapy in Parkinson's disease.
Expert review of neurotherapeutics.
2001 Sep; 1(1):43-51. doi:
10.1586/14737175.1.1.43. [PMID: 19811045]