2-Amino-1,3-propanediol (BioDeep_00000173142)

   

human metabolite blood metabolite


代谢物信息卡片


2-Aminopropane-1,3-diol

化学式: C3H9NO2 (91.0633254)
中文名称: 丝氨醇
谱图信息: 最多检出来源 Homo sapiens(blood) 66.67%

分子结构信息

SMILES: C(C(CO)N)O
InChI: InChI=1S/C3H9NO2/c4-3(1-5)2-6/h3,5-6H,1-2,4H2

描述信息

同义名列表

4 个代谢物同义名

2-Aminopropane-1,3-diol; 2-Amino-1,3-propanediol; Serinol, (+-)-isomer; Serinol



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Kyong-Oh Shin, Sungeun Kim, Byeong Deog Park, Yoshikazu Uchida, Kyungho Park. N-Palmitoyl Serinol Stimulates Ceramide Production through a CB1-Dependent Mechanism in In Vitro Model of Skin Inflammation. International journal of molecular sciences. 2021 Aug; 22(15):. doi: 10.3390/ijms22158302. [PMID: 34361066]
  • Yukiko Kamiya, Yuka Donoshita, Hiroshi Kamimoto, Keiji Murayama, Jumpei Ariyoshi, Hiroyuki Asanuma. Introduction of 2,6-Diaminopurines into Serinol Nucleic Acid Improves Anti-miRNA Performance. Chembiochem : a European journal of chemical biology. 2017 10; 18(19):1917-1922. doi: 10.1002/cbic.201700272. [PMID: 28748559]
  • T Walter, L Collenburg, L Japtok, B Kleuser, S Schneider-Schaulies, N Müller, J Becam, A Schubert-Unkmeir, J N Kong, E Bieberich, J Seibel. Incorporation and visualization of azido-functionalized N-oleoyl serinol in Jurkat cells, mouse brain astrocytes, 3T3 fibroblasts and human brain microvascular endothelial cells. Chemical communications (Cambridge, England). 2016 Jun; 52(55):8612-8614. doi: 10.1039/c6cc02879a. [PMID: 27327378]
  • Donatella Loru, Isabel Peña, José L Alonso, M Eugenia Sanz. Intramolecular interactions in the polar headgroup of sphingosine: serinol. Chemical communications (Cambridge, England). 2016 Mar; 52(18):3615-8. doi: 10.1039/c5cc09423b. [PMID: 26727395]
  • Erhard Bieberich. Ceramide in stem cell differentiation and embryo development: novel functions of a topological cell-signaling lipid and the concept of ceramide compartments. Journal of lipids. 2011; 2011(?):610306. doi: 10.1155/2011/610306. [PMID: 21490805]
  • Jeanne Leblond, Nathalie Mignet, Céline Largeau, Johanne Seguin, Daniel Scherman, Jean Herscovici. Lipopolythiourea transfecting agents: lysine thiourea derivatives. Bioconjugate chemistry. 2008 Jan; 19(1):306-14. doi: 10.1021/bc7001924. [PMID: 18062657]
  • Hiromasa Kiyota. Synthesis of naturally derived bioactive compounds of agricultural interest. Bioscience, biotechnology, and biochemistry. 2006 Feb; 70(2):317-24. doi: 10.1271/bbb.70.317. [PMID: 16495645]
  • X D Liu, X L Wang, L Xie, G J Wang. Different effect of erythromycin on absorption kinetics of nimodipine in male and female rats. European journal of drug metabolism and pharmacokinetics. 2005 Jan; 30(1-2):69-73. doi: 10.1007/bf03226410. [PMID: 16010864]
  • S S Mitchell, D Rhodes, F D Bushman, D J Faulkner. Cyclodidemniserinol trisulfate, a sulfated serinolipid from the Palauan ascidian Didemnum guttatum that inhibits HIV-1 integrase. Organic letters. 2000 Jun; 2(11):1605-7. doi: 10.1021/ol005866o. [PMID: 10841490]
  • C Pelassy, D Mary, C Aussel. Effects of the serine analogues isoserine and serinol on interleukin-2 synthesis and phospholipid metabolism in a human T cell line Jurkat. Journal of lipid mediators. 1991 Jan; 3(1):79-89. doi: ". [PMID: 1768842]