2-(4-Hydroxyphenylazo)benzoic acid (BioDeep_00000173104)

   

human metabolite blood metabolite


代谢物信息卡片


2-[2-(4-hydroxyphenyl)diazen-1-yl]benzoic acid

化学式: C13H10N2O3 (242.069139)
中文名称: 4-羟基偶氮苯-2-羧酸
谱图信息: 最多检出来源 Homo sapiens(blood) 7.69%

分子结构信息

SMILES: C1=CC=C(C(=C1)C(=O)O)N=NC2=CC=C(C=C2)O
InChI: InChI=1S/C13H10N2O3/c16-10-7-5-9(6-8-10)14-15-12-4-2-1-3-11(12)13(17)18/h1-8,16H,(H,17,18)

描述信息

D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D049408 - Luminescent Agents
D004396 - Coloring Agents > D005456 - Fluorescent Dyes

同义名列表

6 个代谢物同义名

2-[2-(4-hydroxyphenyl)diazen-1-yl]benzoic acid; 2-((4-Hydroxyphenyl)azo)benzoic acid; 2-(4-Hydroxybenzene)azobenzoic acid; 2-(4-Hydroxyphenylazo)benzoic acid; 2-(4-Hydroxyphenylazo)benzoate; HABA



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

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  • Siu-Kit Leung, Karen Ying Kwok, Kenneth Yin Zhang, Kenneth Kam-Wing Lo. Design of luminescent biotinylation reagents derived from cyclometalated iridium(III) and rhodium(III) bis(pyridylbenzaldehyde) complexes. Inorganic chemistry. 2010 Jun; 49(11):4984-95. doi: 10.1021/ic100092d. [PMID: 20465281]
  • Michael Volný, Martin Sadílek, Karl E Jackson, Matthew Diener, W Tim Elam, Frantisek Turecek. Matrix-free laser desorption/ionization of ions landed on plasma-treated metal surfaces. Journal of mass spectrometry : JMS. 2008 Sep; 43(9):1265-73. doi: 10.1002/jms.1402. [PMID: 18338315]
  • Hironori Yamazoe, Toshizumi Tanabe. Preparation of water-insoluble albumin film possessing nonadherent surface for cells and ligand binding ability. Journal of biomedical materials research. Part A. 2008 Jul; 86(1):228-34. doi: 10.1002/jbm.a.31654. [PMID: 17975816]
  • Kenneth Kam-Wing Lo, Man-Wai Louie, Ka-Shing Sze, Jason Shing-Yip Lau. Rhenium(I) polypyridine biotin isothiocyanate complexes as the first luminescent biotinylation reagents: synthesis, photophysical properties, biological labeling, cytotoxicity, and imaging studies. Inorganic chemistry. 2008 Jan; 47(2):602-11. doi: 10.1021/ic701675c. [PMID: 18088115]
  • Sotirios Zarogiannis, Vassilios Liakopoulos, Chrissi Hatzoglou, Konstantinos Vogiatzidis, Marios Salmas, Ioannis Stefanidis, Konstantinos Gourgoulianis, Paschalis Adam Molyvdas, Spiros Lafis. Development of an egg-white bioassay for monitoring biotin levels in urine and serum. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry. 2007 May; 23(5):593-5. doi: 10.2116/analsci.23.593. [PMID: 17495407]
  • Yannis Dotsikas, Yannis L Loukas. Application of avidin-biotin technology for the characterization of a model hapten-protein conjugate. Journal of immunoassay & immunochemistry. 2005; 26(4):285-93. doi: 10.1080/15321810500220845. [PMID: 16153013]
  • D Leckband, W Müller, F J Schmitt, H Ringsdorf. Molecular mechanisms determining the strength of receptor-mediated intermembrane adhesion. Biophysical journal. 1995 Sep; 69(3):1162-9. doi: 10.1016/s0006-3495(95)79990-8. [PMID: 8519970]
  • A L Tárnoky, B H Nicholson, D Savva. Nature of the HABA binding to human serum albumin. Biochemical Society transactions. 1991 Aug; 19(3):333S. doi: 10.1042/bst019333s. [PMID: 1686002]
  • J B Pedersen, S M Pedersen, W E Lindup. Bovine albumin-HABA interaction: re-analysis of earlier observations indicates that ligand-induced dimerization and a competitive contaminant operate simultaneously. Biochemical pharmacology. 1990 Mar; 39(6):1138-41. doi: 10.1016/0006-2952(90)90296-w. [PMID: 2157440]
  • T E Rohr, T Cotton, N Fan, P J Tarcha. Immunoassay employing surface-enhanced Raman spectroscopy. Analytical biochemistry. 1989 Nov; 182(2):388-98. doi: 10.1016/0003-2697(89)90613-1. [PMID: 2610355]
  • E E Cepeda, S Shankaran. The effect of multiple exchange transfusions on bilirubin binding. Acta paediatrica Scandinavica. 1985 Jul; 74(4):545-8. doi: 10.1111/j.1651-2227.1985.tb11026.x. [PMID: 4024925]
  • K Murakami, T Sano, S Tsuchie, T Yasunaga. Mechanism of the binding of 2-(4'-hydroxyphenylazo)benzoic acid to bovine serum albumin. Biophysical chemistry. 1985 Feb; 21(2):127-36. doi: 10.1016/0301-4622(85)85014-6. [PMID: 3978216]
  • T Sakurai, S Tsuchiya. Binding of 2-(4'-hydroxyphenylazo) benzoic acid with arginine, lysine, tyrosine and tryptophan modified bovine serum albumin. Journal of pharmacobio-dynamics. 1985 Feb; 8(2):84-9. doi: 10.1248/bpb1978.8.84. [PMID: 3925116]
  • L S Clegg, W E Lindup. Scatchard plots with a positive slope: dependence upon ligand concentration. The Journal of pharmacy and pharmacology. 1984 Nov; 36(11):776-9. doi: 10.1111/j.2042-7158.1984.tb04873.x. [PMID: 6150986]
  • T Sakurai, S Tsuchiya. Characterization of microenvironments of 2-(4'-hydroxyphenylazo)benzoic acid bound to bovine serum albumin by studying the solvent effects. Journal of pharmaceutical sciences. 1984 Apr; 73(4):507-12. doi: 10.1002/jps.2600730419. [PMID: 6726635]
  • C J Bowmer, W E Lindup. Decreased drug binding in uraemia: effect of indoxyl sulphate and other endogenous substances on the binding of drugs and dyes to human albumin. Biochemical pharmacology. 1982 Feb; 31(3):319-23. doi: 10.1016/0006-2952(82)90177-0. [PMID: 6803808]
  • T Sakurai, S Tsuchiya, H Matsumaru. Assignment of circular dichroism spectra of 2-(4'-hydroxyphenylazo)benzoic acid induced by bovine serum albumin to the azo form. Journal of pharmacobio-dynamics. 1981 Jun; 4(6):451-4. doi: 10.1248/bpb1978.4.451. [PMID: 7288561]
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  • T Sakurai, S Tsuchiya, H Matsumaru. Effects of phenylbutazone and mefenamic acid on two classes of binding sites of 2-(4'-hydroxyphenylazo)benzoic acid on bovine serum albumin characterized by absorption spectra and circular dichroism spectra. Journal of pharmacobio-dynamics. 1981 May; 4(5):345-55. doi: 10.1248/bpb1978.4.345. [PMID: 7288552]
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  • T Sakurai, S Tsuchiya, H Matsumaru. Binding of 2-(4'-hydroxyphenylazo)benzoic acid to bovine serum albumin characterized by optical spectroscopy and equilibrium dialysis. Journal of pharmacobio-dynamics. 1981 Jan; 4(1):65-8. doi: 10.1248/bpb1978.4.65. [PMID: 7277193]
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  • C J Bowmer, W E Lindup. Inverse dependence of binding constants upon albumin concentration. Results for L-tryptophan and three anionic dyes. Biochimica et biophysica acta. 1980 Jul; 624(1):260-70. doi: 10.1016/0005-2795(80)90245-7. [PMID: 6893287]
  • A K Brown, J Eisinger, W E Blumberg, J Flores, G Boyle, A A Lamola. A rapid fluorometric method for determining bilirubin levels and binding in the blood of neonates: comparisons with a diazo method and with 2-(4'-hydroxybenzene)azobenzoic acid dye binding. Pediatrics. 1980 Apr; 65(4):767-76. doi: NULL. [PMID: 7367084]