1Propylthiouracil (BioDeep_00000173083)
human metabolite blood metabolite
代谢物信息卡片
化学式: C7H10N2OS (170.0514)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCN1C=CC(=O)NC1=S
InChI: InChI=1S/C7H10N2OS/c1-2-4-9-5-3-6(10)8-7(9)11/h3,5H,2,4H2,1H3,(H,8,10,11)
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Chunsheng Liu, Xiaowei Zhang, Jun Deng, Markus Hecker, Abdulaziz Al-Khedhairy, John P Giesy, Bingsheng Zhou. Effects of prochloraz or propylthiouracil on the cross-talk between the HPG, HPA, and HPT axes in zebrafish.
Environmental science & technology.
2011 Jan; 45(2):769-75. doi:
10.1021/es102659p. [PMID: 21158436] - Shu-Ching Chang, Julie R Thibodeaux, Mary L Eastvold, David J Ehresman, James A Bjork, John W Froehlich, Christopher Lau, Ravinder J Singh, Kendall B Wallace, John L Butenhoff. Thyroid hormone status and pituitary function in adult rats given oral doses of perfluorooctanesulfonate (PFOS).
Toxicology.
2008 Jan; 243(3):330-9. doi:
10.1016/j.tox.2007.10.014. [PMID: 18063289] - S Panda, A Kar. Annona squamosa seed extract in the regulation of hyperthyroidism and lipid-peroxidation in mice: possible involvement of quercetin.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2007 Dec; 14(12):799-805. doi:
10.1016/j.phymed.2006.12.001. [PMID: 17291737] - K Ohta, M Shimizu, T Yokoyama, K Ohta, A Nakai, A Seno, Y Kasahara, A Yachie, M Fujieda, S Koizumi. Analysis of MPO-ANCA subtypes in a patient with propylthiouracil-induced vasculitis with multiple complications.
Clinical nephrology.
2007 Nov; 68(5):315-21. doi:
10.5414/cnp68315. [PMID: 18044264] - H S Parmar, S Panda, R Jatwa, A Kar. Cardio-protective role of Terminalia arjuna bark extract is possibly mediated through alterations in thyroid hormones.
Die Pharmazie.
2006 Sep; 61(9):793-5. doi:
". [PMID: 17020158] - S V S Rana, Tanu Allen. Influence of thyroxine and n-propylthiouracil on nephro-toxicity of inorganic arsenic in rat.
Toxicology and industrial health.
2006 Apr; 22(3):137-45. doi:
10.1191/0748233706th251oa. [PMID: 16716044] - María Belén Hapon, Silvia M Varas, Graciela A Jahn, María S Giménez. Effects of hypothyroidism on mammary and liver lipid metabolism in virgin and late-pregnant rats.
Journal of lipid research.
2005 Jun; 46(6):1320-30. doi:
10.1194/jlr.m400325-jlr200. [PMID: 15741655] - F Yu, M-H Zhao, Y-K Zhang, Y Zhang, H-Y Wang. Anti-endothelial cell antibodies (AECA) in patients with propylthiouracil (PTU)-induced ANCA positive vasculitis are associated with disease activity.
Clinical and experimental immunology.
2005 Mar; 139(3):569-74. doi:
10.1111/j.1365-2249.2005.02725.x. [PMID: 15730404] - Minoru Hatsuta, Keiko Abe, Kazuhiro Tamura, Takamitsu Ryuno, Gen Watanabe, Kazuyoshi Taya, Hiroshi Kogo. Effects of hypothyroidism on the estrous cycle and reproductive hormones in mature female rat.
European journal of pharmacology.
2004 Feb; 486(3):343-8. doi:
10.1016/j.ejphar.2003.12.035. [PMID: 14985057] - S Panda, A Kar. Fruit extract of Emblica officinalis ameliorates hyperthyroidism and hepatic lipid peroxidation in mice.
Die Pharmazie.
2003 Oct; 58(10):753-5. doi:
NULL. [PMID: 14609291] - S Choudhury, G B N Chainy, M M Mishro. Experimentally induced hypo- and hyper-thyroidism influence on the antioxidant defence system in adult rat testis.
Andrologia.
2003 Jun; 35(3):131-40. doi:
10.1046/j.1439-0272.2003.00548.x. [PMID: 12780529] - Pankaj Tahiliani, Anand Kar. Mitigation of thyroxine-induced hyperglycaemia by two plant extracts.
Phytotherapy research : PTR.
2003 Mar; 17(3):294-6. doi:
10.1002/ptr.1121. [PMID: 12672166]
