1,2,4-Triazole (BioDeep_00000173045)

   

human metabolite blood metabolite


代谢物信息卡片


1,2,4-Triazole, potassium salt

化学式: C2H3N3 (69.0326958)
中文名称: 1,2,4-三氮唑
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=NC=NN1
InChI: InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)

描述信息

同义名列表

4 个代谢物同义名

1,2,4-Triazole, potassium salt; 1H-1,2,4-Triazole; 1,2,4-Triazole; S-Triazole



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Karpenko Yuriy, Gulnur Kusdemir, Parchenko Volodymyr, Burak Tüzün, Parham Taslimi, Omer Faruk Karatas, Khilkovets Anastasia, Parchenko Maryna, Koray Sayın. A biochemistry-oriented drug design: synthesis, anticancer activity, enzymes inhibition, molecular docking studies of novel 1,2,4-triazole derivatives. Journal of biomolecular structure & dynamics. 2024 Feb; 42(3):1220-1236. doi: 10.1080/07391102.2023.2253906. [PMID: 37671856]
  • Limin Wang, Xiaoyu Song, Yi-Nan Cheng, Senxiang Cheng, Tong Chen, Honglian Li, Jingming Yan, Xiafei Wang, Haifeng Zhou. 1,2,4-Triazole benzamide derivative TPB against Gaeumannomyces graminis var. tritici as a novel dual-target fungicide inhibiting ergosterol synthesis and adenine nucleotide transferase function. Pest management science. 2023 Nov; ?(?):. doi: 10.1002/ps.7900. [PMID: 38010196]
  • Yaoqiang Lao, Yang Wang, Jianwen Chen, Ping Huang, Ruiqi Su, Jinguo Shi, Caibao Jiang, Jingxia Zhang. Synthesis and biological evaluation of 1,2,4-triazole derivatives as potential Nrf2 activators for the treatment of cerebral ischemic injury. European journal of medicinal chemistry. 2022 Jun; 236(?):114315. doi: 10.1016/j.ejmech.2022.114315. [PMID: 35390713]
  • Tao Huang, Haibo Jiang, Yuanhui Zhao, Jia He, Hongguang Cheng, Christopher J Martyniuk. A comprehensive review of 1,2,4-triazole fungicide toxicity in zebrafish (Danio rerio): A mitochondrial and metabolic perspective. The Science of the total environment. 2022 Feb; 809(?):151177. doi: 10.1016/j.scitotenv.2021.151177. [PMID: 34699814]
  • Irum Shahzadi, Ameer Fawad Zahoor, Burak Tüzün, Asim Mansha, Muhammad Naveed Anjum, Azhar Rasul, Ali Irfan, Katarzyna Kotwica-Mojzych, Mariusz Mojzych. Repositioning of acefylline as anti-cancer drug: Synthesis, anticancer and computational studies of azomethines derived from acefylline tethered 4-amino-3-mercapto-1,2,4-triazole. PloS one. 2022; 17(12):e0278027. doi: 10.1371/journal.pone.0278027. [PMID: 36520942]
  • Wu-Bin Shao, Pei-Yi Wang, Zi-Mian Fang, Jin-Jing Wang, Deng-Xuan Guo, Jin Ji, Xiang Zhou, Pu-Ying Qi, Li-Wei Liu, Song Yang. Synthesis and Biological Evaluation of 1,2,4-Triazole Thioethers as Both Potential Virulence Factor Inhibitors against Plant Bacterial Diseases and Agricultural Antiviral Agents against Tobacco Mosaic Virus Infections. Journal of agricultural and food chemistry. 2021 Dec; 69(50):15108-15122. doi: 10.1021/acs.jafc.1c05202. [PMID: 34905356]
  • Muhan Ding, Suran Wan, Nan Wu, Ya Yan, Junhong Li, Xiaoping Bao. Synthesis, Structural Characterization, and Antibacterial and Antifungal Activities of Novel 1,2,4-Triazole Thioether and Thiazolo[3,2-b]-1,2,4-triazole Derivatives Bearing the 6-Fluoroquinazolinyl Moiety. Journal of agricultural and food chemistry. 2021 Dec; 69(50):15084-15096. doi: 10.1021/acs.jafc.1c02144. [PMID: 34881871]
  • Yan-En Wang, Dongchen Yang, Jingqian Huo, Lai Chen, Zhanhai Kang, Jianyou Mao, Jinlin Zhang. Design, Synthesis, and Herbicidal Activity of Thioether Containing 1,2,4-Triazole Schiff Bases as Transketolase Inhibitors. Journal of agricultural and food chemistry. 2021 Oct; 69(40):11773-11780. doi: 10.1021/acs.jafc.1c01804. [PMID: 34587736]
  • Noha H Amin, Mohamed T El-Saadi, Ahmed A Ibrahim, Hamdy M Abdel-Rahman. Design, synthesis and mechanistic study of new 1,2,4-triazole derivatives as antimicrobial agents. Bioorganic chemistry. 2021 06; 111(?):104841. doi: 10.1016/j.bioorg.2021.104841. [PMID: 33798851]
  • Youyi Peng, Qiang Zhang, William J Welsh. Novel Sigma 1 Receptor Antagonists as Potential Therapeutics for Pain Management. Journal of medicinal chemistry. 2021 01; 64(1):890-904. doi: 10.1021/acs.jmedchem.0c01964. [PMID: 33372782]
  • Xuemei Ge, Zhi Xu. 1,2,4-Triazole hybrids with potential antibacterial activity against methicillin-resistant Staphylococcus aureus. Archiv der Pharmazie. 2021 Jan; 354(1):e2000223. doi: 10.1002/ardp.202000223. [PMID: 32985011]
  • Sami A Al-Hussain, Thoraya A Farghaly, Magdi E A Zaki, Hanan G Abdulwahab, Nadia T Al-Qurashi, Zeinab A Muhammad. Discovery of novel indolyl-1,2,4-triazole hybrids as potent vascular endothelial growth factor receptor-2 (VEGFR-2) inhibitors with potential anti-renal cancer activity. Bioorganic chemistry. 2020 12; 105(?):104330. doi: 10.1016/j.bioorg.2020.104330. [PMID: 33038552]
  • Jun Shi, Muhan Ding, Na Luo, Suran Wan, Peijia Li, Junhong Li, Xiaoping Bao. Design, Synthesis, Crystal Structure, and Antimicrobial Evaluation of 6-Fluoroquinazolinylpiperidinyl-Containing 1,2,4-Triazole Mannich Base Derivatives against Phytopathogenic Bacteria and Fungi. Journal of agricultural and food chemistry. 2020 Sep; 68(36):9613-9623. doi: 10.1021/acs.jafc.0c01365. [PMID: 32786823]
  • Eugenia Stingaci, Marina Zveaghinteva, Serghei Pogrebnoi, Lucian Lupascu, Vladimir Valica, Livia Uncu, Anastasia Smetanscaia, Maricica Drumea, Anthi Petrou, Ana Ciric, Jasmina Glamoclija, Marina Sokovic, Victor Kravtsov, Athina Geronikaki, Fliur Macaev. New vinyl-1,2,4-triazole derivatives as antimicrobial agents: Synthesis, biological evaluation and molecular docking studies. Bioorganic & medicinal chemistry letters. 2020 09; 30(17):127368. doi: 10.1016/j.bmcl.2020.127368. [PMID: 32738986]
  • Angelina Petrović, Marko Živanović, Ralph Puchta, Dušan Ćoćić, Andreas Scheurer, Nevena Milivojevic, Jovana Bogojeski. Experimental and quantum chemical study оn the DNA/protein binding and the biological activity of a rhodium(iii) complex with 1,2,4-triazole as an inert ligand. Dalton transactions (Cambridge, England : 2003). 2020 Jul; 49(26):9070-9085. doi: 10.1039/d0dt01343a. [PMID: 32568355]
  • Ya-Zhou Zhang, Hai-Lin Liu, Qian-Song He, Zhi Xu. The In Vitro Anticancer Activity and Potential Mechanism of Action of 1-[(1R,2S)-2-fluorocyclopropyl]Ciprofloxacin-(4-methyl/phenyl/benzyl-3- aryl)-1,2,4-triazole-5(4H)-thione Hybrids. Current topics in medicinal chemistry. 2020; 20(16):1493-1498. doi: 10.2174/1568026620666200310123723. [PMID: 32156237]
  • Fayçal Hichri, Amel Omri, Aisha Saad Mana Hossan, Hichem Ben Jannet. Alpha-glucosidase and amylase inhibitory effects of Eruca vesicaria subsp. longirostris essential oils: synthesis of new 1,2,4-triazole-thiol derivatives and 1,3,4-thiadiazole with potential inhibitory activity. Pharmaceutical biology. 2019 Dec; 57(1):564-570. doi: 10.1080/13880209.2019.1642363. [PMID: 31454271]
  • Takanori Koike, Ryota Shiraki, Daisuke Sasuga, Mitsuru Hosaka, Tomoaki Kawano, Hiroki Fukudome, Kazuo Kurosawa, Ayako Moritomo, Shinya Mimasu, Hirofumi Ishii, Seiji Yoshimura. Discovery and Biological Evaluation of Potent and Orally Active Human 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors for the Treatment of Type 2 Diabetes Mellitus. Chemical & pharmaceutical bulletin. 2019; 67(8):824-838. doi: 10.1248/cpb.c19-00211. [PMID: 31366832]
  • Sana Tariq, Payal Kamboj, Ozair Alam, Mohd Amir. 1,2,4-Triazole-based benzothiazole/benzoxazole derivatives: Design, synthesis, p38α MAP kinase inhibition, anti-inflammatory activity and molecular docking studies. Bioorganic chemistry. 2018 12; 81(?):630-641. doi: 10.1016/j.bioorg.2018.09.015. [PMID: 30253336]
  • Naeem Akhtar Virk, Azizur Rehman, Muhammad Athar Abbasi, Sabahat Zahra Siddiqui, Asma Ashraf, Mehreen Lateef, Hira Javed, Javed Iqbal, Hira Khalid, Shafiullah Khan. In silico and BSA binding study of some new biological analogs of 1,2,4-triazolependant with azinane through microwave and conventional synthesis. Pakistan journal of pharmaceutical sciences. 2018 Nov; 31(6 (Supplementary):2645-2654. doi: . [PMID: 30587474]
  • Sana Tariq, Ozair Alam, Mohammad Amir. Synthesis, p38α MAP kinase inhibition, anti-inflammatory activity, and molecular docking studies of 1,2,4-triazole-based benzothiazole-2-amines. Archiv der Pharmazie. 2018 Apr; 351(3-4):e1700304. doi: 10.1002/ardp.201700304. [PMID: 29611883]
  • Shima Shahrivari, Farnoush Faridbod, Mohammad Reza Ganjali. Highly selective and sensitive colorimetric determination of Cr3+ ion by 4-amino-5-methyl-4H-1,2,4-triazole-3-thiol functionalized Au nanoparticles. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2018 Feb; 191(?):189-194. doi: 10.1016/j.saa.2017.09.064. [PMID: 29032343]
  • Marc Lamshoeft, Zhenglei Gao, Herbert Resseler, Carola Schriever, Robin Sur, Paul Sweeney, Sarah Webb, Birgit Zillgens, Marco U Reitz. Evaluation of a novel test design to determine uptake of chemicals by plant roots. The Science of the total environment. 2018 Feb; 613-614(?):10-19. doi: 10.1016/j.scitotenv.2017.08.314. [PMID: 28892723]
  • Rasha R Radwan, Nashwa H Zaher, Marwa G El-Gazzar. Novel 1,2,4-triazole derivatives as antitumor agents against hepatocellular carcinoma. Chemico-biological interactions. 2017 Aug; 274(?):68-79. doi: 10.1016/j.cbi.2017.07.008. [PMID: 28693887]
  • Ruiqin Wu, Haobo Wu, Xinbai Jiang, Jinyou Shen, Muhammad Faheem, Xiuyun Sun, Jiansheng Li, Weiqing Han, Lianjun Wang, Xiaodong Liu. The key role of biogenic manganese oxides in enhanced removal of highly recalcitrant 1,2,4-triazole from bio-treated chemical industrial wastewater. Environmental science and pollution research international. 2017 Apr; 24(11):10570-10583. doi: 10.1007/s11356-017-8641-1. [PMID: 28283969]
  • Dong Ju Lee, Hyun Jun Choi, Mid-Eum Moon, Youn-Tae Chi, Kon-Young Ji, Doil Choi. Superoxide serves as a putative signal molecule for plant cell division: overexpression of CaRLK1 promotes the plant cell cycle via accumulation of O2- and decrease in H2 O2. Physiologia plantarum. 2017 Feb; 159(2):228-243. doi: 10.1111/ppl.12487. [PMID: 27528370]
  • Prateek Tyagi, Monika Tyagi, Swati Agrawal, Sulekh Chandra, Himanshu Ojha, Mallika Pathak. Synthesis, characterization of 1,2,4-triazole Schiff base derived 3d-metal complexes: Induces cytotoxicity in HepG2, MCF-7 cell line, BSA binding fluorescence and DFT study. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2017 Jan; 171(?):246-257. doi: 10.1016/j.saa.2016.08.008. [PMID: 27541797]
  • Yong Wang, Xiaoqing Sun, Di Yang, Zhuang Guo, Xuxu Fan, Minhua Nie, Feng Zhang, Yue Liu, Yue Li, Yulin Wang, Ping Gong, Yajing Liu. Design, synthesis, and structure-activity relationship of novel and effective apixaban derivatives as FXa inhibitors containing 1,2,4-triazole/pyrrole derivatives as P2 binding element. Bioorganic & medicinal chemistry. 2016 11; 24(21):5646-5661. doi: 10.1016/j.bmc.2016.09.024. [PMID: 27663548]
  • Marco Scheurer, Heinz-Jürgen Brauch, Carsten K Schmidt, Frank Sacher. Occurrence and fate of nitrification and urease inhibitors in the aquatic environment. Environmental science. Processes & impacts. 2016 Aug; 18(8):999-1010. doi: 10.1039/c6em00014b. [PMID: 27058057]
  • Pei-Liang Zhao, Peng Chen, Qiu Li, Meng-Jin Hu, Peng-Cheng Diao, En-Shan Pan, Wen-Wei You. Design, synthesis and biological evaluation of novel 3-alkylsulfanyl-4-amino-1,2,4-triazole derivatives. Bioorganic & medicinal chemistry letters. 2016 08; 26(15):3679-83. doi: 10.1016/j.bmcl.2016.05.086. [PMID: 27287368]
  • A E Parlak, S Celik, M Karatepe, S Turkoglu, N O Alayunt, S D Dastan, M Ulas, S Sandal, S Tekin, M Koparir. Investigation of biological effects of some Mannich Bases containing Bis-1,2,4- Triazole. Cellular and molecular biology (Noisy-le-Grand, France). 2016 Jun; 62(7):46-54. doi: NULL. [PMID: 27453272]
  • Yao Zhang, Jie Li, Guoyu Ren, Baofu Qin, Haixia Ma. Synthesis, crystal structure and antifungal activity of a divalent cobalt(II) complex with uniconazole. Acta crystallographica. Section C, Structural chemistry. 2016 06; 72(Pt 6):485-90. doi: 10.1107/s2053229616007750. [PMID: 27256696]
  • Eyüp Başaran, Ayşegül Karaküçük-Iyidoğan, Dominique Schols, Emine Elçin Oruç-Emre. Synthesis of Novel Chiral Sulfonamide-Bearing 1,2,4-Triazole-3-thione Analogs Derived from D- and L-Phenylalanine Esters as Potential Anti-Influenza Agents. Chirality. 2016 06; 28(6):495-513. doi: 10.1002/chir.22607. [PMID: 27225330]
  • Hoh-Gyu Hahn, Jung-Sup Choi, Hee Kyung Lim, Kee-In Lee, In Taek Hwang. Triazolyl phenyl disulfides: 8-Amino-7-oxononanoate synthase inhibitors as potential herbicides. Pesticide biochemistry and physiology. 2015 Nov; 125(?):78-83. doi: 10.1016/j.pestbp.2015.05.006. [PMID: 26615154]
  • Ebtehal S Al-Abdullah, Hanaa M Al-Tuwaijri, Hanan M Hassan, Monirah A Al-Alshaikh, Elsayed E Habib, Ali A El-Emam. Synthesis, Antimicrobial and Hypoglycemic Activities of Novel N-(1-Adamantyl)carbothioamide Derivatives. Molecules (Basel, Switzerland). 2015 May; 20(5):8125-43. doi: 10.3390/molecules20058125. [PMID: 25955889]
  • A S Barneze, E P Minet, C C Cerri, T Misselbrook. The effect of nitrification inhibitors on nitrous oxide emissions from cattle urine depositions to grassland under summer conditions in the UK. Chemosphere. 2015 Jan; 119(?):122-129. doi: 10.1016/j.chemosphere.2014.06.002. [PMID: 24973531]
  • Chandrashekar Aswathanarayanappa, Eswarappa Bheemappa, Yadav D Bodke, Peethambar S Krishnegowda, Srinivas P Venkata, Raghu Ningegowda. Synthesis and evaluation of antioxidant properties of novel 1,2,4-triazole-based schiff base heterocycles. Archiv der Pharmazie. 2013 Dec; 346(12):922-30. doi: 10.1002/ardp.201300202. [PMID: 24301964]
  • Mohamed Abdel-Aziz, Gamal El-Din A A Abuo-Rahma, Eman A M Beshr, Taha F S Ali. New nitric oxide donating 1,2,4-triazole/oxime hybrids: synthesis, investigation of anti-inflammatory, ulceroginic liability and antiproliferative activities. Bioorganic & medicinal chemistry. 2013 Jul; 21(13):3839-49. doi: 10.1016/j.bmc.2013.04.022. [PMID: 23665142]
  • Muhammad Salman, Mahwish Iqbal, El Sayed H El Ashry, Shamsa Kanwal. Robust one pot synthesis of colloidal silver nanoparticles by simple redox method and absorbance recovered sensing. Biosensors & bioelectronics. 2012 Jun; 36(1):236-41. doi: 10.1016/j.bios.2012.04.025. [PMID: 22578269]
  • Kazuhiro Yamada, Yuko Yoshizawa, Keimei Oh. Synthesis of 2RS,4RS-1-[2-phenyl-4-[2-(2-trifluromethoxy-phenoxy)-ethyl]-1,3-dioxolan-2-yl-methyl]-1H-1,2,4-triazole derivatives as potent inhibitors of brassinosteroid biosynthesis. Molecules (Basel, Switzerland). 2012 Apr; 17(4):4460-73. doi: 10.3390/molecules17044460. [PMID: 22504831]
  • Cr Biju, K Ilango, Manju Prathap, K Rekha. Design and Microwave-assisted Synthesis of 1,3,4-Oxadiazole Derivatives for Analgesic and Anti-inflammatory Activity. Journal of young pharmacists : JYP. 2012 Jan; 4(1):33-7. doi: 10.4103/0975-1483.93576. [PMID: 22523458]
  • Takashi Sugane, Takahiko Tobe, Wataru Hamaguchi, Itsuro Shimada, Kyoichi Maeno, Junji Miyata, Takeshi Suzuki, Tetsuya Kimizuka, Takuma Morita, Shuichi Sakamoto, Shin-ichi Tsukamoto. Synthesis and biological evaluation of (4H-1,2,4-triazol-4-yl)isoquinoline derivatives as selective glycine transporter 1 inhibitors. Bioorganic & medicinal chemistry. 2012 Jan; 20(1):34-41. doi: 10.1016/j.bmc.2011.11.038. [PMID: 22177408]
  • Aalt D J van Dijk, Giuseppa Morabito, Martijn Fiers, Roeland C H J van Ham, Gerco C Angenent, Richard G H Immink. Sequence motifs in MADS transcription factors responsible for specificity and diversification of protein-protein interaction. PLoS computational biology. 2010 Nov; 6(11):e1001017. doi: 10.1371/journal.pcbi.1001017. [PMID: 21124869]
  • Bidhan A Shinkre, T Santhosh Kumar, Zhan-Guo Gao, Francesca Deflorian, Kenneth A Jacobson, William C Trenkle. Synthesis and evaluation of 1,2,4-triazolo[1,5-c]pyrimidine derivatives as A2A receptor-selective antagonists. Bioorganic & medicinal chemistry letters. 2010 Oct; 20(19):5690-4. doi: 10.1016/j.bmcl.2010.08.021. [PMID: 20801028]
  • S Peri Aytaç, Birsen Tozkoparan, F Betül Kaynak, Göknur Aktay, Ozgür Göktaş, Songül Unüvar. Synthesis of 3,6-disubstituted 7H-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazines as novel analgesic/anti-inflammatory compounds. European journal of medicinal chemistry. 2009 Nov; 44(11):4528-38. doi: 10.1016/j.ejmech.2009.06.026. [PMID: 19632747]
  • Gamal A Idrees, Omar M Aly, Gamal El-Din A A Abuo-Rahma, M F Radwan. Design, synthesis and hypolipidemic activity of novel 2-(naphthalen-2-yloxy)propionic acid derivatives as desmethyl fibrate analogs. European journal of medicinal chemistry. 2009 Oct; 44(10):3973-80. doi: 10.1016/j.ejmech.2009.04.026. [PMID: 19450906]
  • Goknur Aktay, Birsen Tozkoparan, Mevlut Ertan. Investigation of antioxidant properties of some 6-(alpha-aminobenzyl)thiazolo[3,2-b]-1,2,4-triazole-5-ol compounds. Journal of enzyme inhibition and medicinal chemistry. 2009 Jun; 24(3):898-902. doi: 10.1080/14756360802519798. [PMID: 18951285]
  • Takaaki Umano, Keiji Shiraishi, Yasushi Minobe, Kanji Yamasaki. Uterotrophic assay, Hershberger assay, and subacute oral toxicity study of 3-amino-1,2,4-triazole based on the Organization for Economic Co-operation and Development draft protocols. Archives of toxicology. 2009 May; 83(5):459-67. doi: 10.1007/s00204-008-0357-z. [PMID: 18779953]
  • Weimin Yang, Robert M Lust, April Bofferding, Christopher J Wingard. Nitric oxide and catalase-sensitive relaxation by scutellarin in the mouse thoracic aorta. Journal of cardiovascular pharmacology. 2009 Jan; 53(1):66-76. doi: 10.1097/fjc.0b013e318195d776. [PMID: 19129733]
  • Harish Kumar, Sadique A Javed, Suroor A Khan, Mohammad Amir. 1,3,4-Oxadiazole/thiadiazole and 1,2,4-triazole derivatives of biphenyl-4-yloxy acetic acid: synthesis and preliminary evaluation of biological properties. European journal of medicinal chemistry. 2008 Dec; 43(12):2688-98. doi: 10.1016/j.ejmech.2008.01.039. [PMID: 18395299]
  • Mohd Amir, Harish Kumar, S A Javed. Condensed bridgehead nitrogen heterocyclic system: synthesis and pharmacological activities of 1,2,4-triazolo-[3,4-b]-1,3,4-thiadiazole derivatives of ibuprofen and biphenyl-4-yloxy acetic acid. European journal of medicinal chemistry. 2008 Oct; 43(10):2056-66. doi: 10.1016/j.ejmech.2007.09.025. [PMID: 18023930]
  • Hiroyuki Matsukizono, Keita Kuroiwa, Nobuo Kimizuka. Lipid-packaged linear iron(II) triazole complexes in solution: controlled spin conversion via solvophobic self-assembly. Journal of the American Chemical Society. 2008 Apr; 130(17):5622-3. doi: 10.1021/ja711355j. [PMID: 18386889]
  • Mohammad Amir, Harish Kumar, Sadique A Javed. Non-carboxylic analogues of naproxen: design, synthesis, and pharmacological evaluation of some 1,3,4-oxadiazole/thiadiazole and 1,2,4-triazole derivatives. Archiv der Pharmazie. 2007 Nov; 340(11):577-85. doi: 10.1002/ardp.200700065. [PMID: 17924361]
  • Shusei Sato, Yoshikazu Shimoda, Akiko Muraki, Mitsuyo Kohara, Yasukazu Nakamura, Satoshi Tabata. A large-scale protein protein interaction analysis in Synechocystis sp. PCC6803. DNA research : an international journal for rapid publication of reports on genes and genomes. 2007 Oct; 14(5):207-16. doi: 10.1093/dnares/dsm021. [PMID: 18000013]
  • Jian-yu Jin, Li-xue Zhang, An-jiang Zhang, Xin-Xiang Lei, Jiang-Hai Zhu. Synthesis and biological activity of some novel derivatives of 4-amino-3-(D-galactopentitol-1-yl)-5-mercapto-1,2,4-triazole. Molecules (Basel, Switzerland). 2007 Jul; 12(8):1596-605. doi: 10.3390/12081596. [PMID: 17960075]
  • Xiao-Xia Ye, Zhen-Fei Chen, An-Jiang Zhang, Li-Xue Zhang. Synthesis and biological evaluation of some novel Schiff's bases from 1,2,4-triazole. Molecules (Basel, Switzerland). 2007 Jul; 12(6):1202-9. doi: 10.3390/12061202. [PMID: 17876289]
  • Huoqiang Huang, Xulin Pan, Ninghua Tan, Guangzhi Zeng, Changjiu Ji. 3D-QSAR study of sulfonamide inhibitors of human carbonic anhydrase II. European journal of medicinal chemistry. 2007 Mar; 42(3):365-72. doi: 10.1016/j.ejmech.2006.09.022. [PMID: 17118494]
  • M Krauze, J Truchliński, M Cendrowska-Pinkosz. Some biochemical parameters of blood plasma of turkey-hens following administration of 1,2,4-triasole derivative. Polish journal of veterinary sciences. 2007; 10(2):109-12. doi: NULL. [PMID: 17882935]
  • Nazar Trotsko, Maria Dobosz, Victor Lukianchuk. Synthesis of amides of 5-arylidene-2,4-dioxothiazolidine-3-acetic acid with 1,2,4-triazole system. Acta poloniae pharmaceutica. 2006 Jan; 63(1):47-52. doi: ". [PMID: 17515329]
  • J Truchliński, M Krauze, M Cendrowska-Pinkosz, B Modzelewska-Banachiewicz. Influence of garlic, synthetic 1,2,4-triasole derivative and herbal preparation echinovit C on selected indices of turkey-hens non-specific immunity. Polish journal of veterinary sciences. 2006; 9(1):51-5. doi: ". [PMID: 16573275]
  • Tetyana V Bagnyukova, Kenneth B Storey, Volodymyr I Lushchak. Adaptive response of antioxidant enzymes to catalase inhibition by aminotriazole in goldfish liver and kidney. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 2005 Nov; 142(3):335-41. doi: 10.1016/j.cbpb.2005.08.003. [PMID: 16168691]
  • Tetyana V Bagnyukova, Olena Yu Vasylkiv, Kenneth B Storey, Volodymyr I Lushchak. Catalase inhibition by amino triazole induces oxidative stress in goldfish brain. Brain research. 2005 Aug; 1052(2):180-6. doi: 10.1016/j.brainres.2005.06.002. [PMID: 16023088]
  • Han-Gon Choi, H Won Jun, Dae-Duk Kim, Hongkee Sah, Bong Kyu Yoo, Chul Soon Yong. Simultaneous determination of cefatrizine and clavulanic acid in dog plasma by HPLC. Journal of pharmaceutical and biomedical analysis. 2004 Apr; 35(1):221-31. doi: 10.1016/j.jpba.2004.01.010. [PMID: 15030898]
  • J Truchliński, E Kifer-Wysocka, B Modzelewska-Banachiewicz. Action of 1,2,4-triazole and 1,2,4-triazine derivatives on cells of green monkey kidney in in vitro culture. Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina. 2000; 55(?):37-43. doi: NULL. [PMID: 11482100]
  • J C García-Gonzalez, R Méndez, J Martín-Villacorta. Determination of piperacillin and mezlocillin in human serum and urine by high-performance liquid chromatography after derivatisation with 1,2,4-triazole. Journal of chromatography. A. 1998 Jul; 812(1-2):213-20. doi: 10.1016/s0021-9673(98)00389-6. [PMID: 9691320]
  • J Haginaka, J Wakai. High-performance liquid chromatographic assay of carbenicillin, ticarcillin and sulbenicillin in serum and urine using pre-column reaction with 1,2,4-triazole and mercury(II) chloride. The Analyst. 1985 Oct; 110(10):1185-8. doi: 10.1039/an9851001185. [PMID: 4083496]