1H-1,2,3-Benzotriazol-4-amine (BioDeep_00000173043)

   

human metabolite blood metabolite


代谢物信息卡片


1H-1,2,3-Benzotriazol-4-amine

化学式: C6H6N4 (134.0592)
中文名称: 1H-苯并三唑-4-胺
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC2=NNN=C2C(=C1)N
InChI: InChI=1S/C6H6N4/c7-4-2-1-3-5-6(4)9-10-8-5/h1-3H,7H2,(H,8,9,10)

描述信息

同义名列表

3 个代谢物同义名

1H-1,2,3-Benzotriazol-4-amine; 2H-1,2,3-benzotriazol-4-amine; 1H-benzotriazol-4-amine



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Shinji Shimizu, Ryo Atsumi, Kenichi Itokawa, Masaru Iwasaki, Takanori Aoki, Chiho Ono, Takashi Izumi, Kenichi Sudo, Osamu Okazaki. Metabolism-dependent hepatotoxicity of amodiaquine in glutathione-depleted mice. Archives of toxicology. 2009 Jul; 83(7):701-7. doi: 10.1007/s00204-009-0436-9. [PMID: 19479240]
  • Jonathan W Martin, Katie Chan, Scott A Mabury, Peter J O'Brien. Bioactivation of fluorotelomer alcohols in isolated rat hepatocytes. Chemico-biological interactions. 2009 Feb; 177(3):196-203. doi: 10.1016/j.cbi.2008.11.001. [PMID: 19041856]
  • Bahar Tunctan, Fariborz A Yaghini, Anne Estes, Kafait U Malik. Prostaglandins inhibit cytochrome P450 4A activity and contribute to endotoxin-induced hypotension in rats via nitric oxide production. Archives of pharmacal research. 2008 Jul; 31(7):856-65. doi: 10.1007/s12272-001-1238-x. [PMID: 18704327]
  • David Hallifax, J Brian Houston. Saturable uptake of lipophilic amine drugs into isolated hepatocytes: mechanisms and consequences for quantitative clearance prediction. Drug metabolism and disposition: the biological fate of chemicals. 2007 Aug; 35(8):1325-32. doi: 10.1124/dmd.107.015131. [PMID: 17470525]
  • David Hallifax, J Brian Houston. Uptake and intracellular binding of lipophilic amine drugs by isolated rat hepatocytes and implications for prediction of in vivo metabolic clearance. Drug metabolism and disposition: the biological fate of chemicals. 2006 Nov; 34(11):1829-36. doi: 10.1124/dmd.106.010413. [PMID: 16882765]
  • Bahar Tunctan, Fariborz A Yaghini, Anne Estes, Kafait U Malik. Inhibition by nitric oxide of cytochrome P450 4A activity contributes to endotoxin-induced hypotension in rats. Nitric oxide : biology and chemistry. 2006 Feb; 14(1):51-7. doi: 10.1016/j.niox.2005.09.006. [PMID: 16288975]
  • Mohammad A Newaz, Adebayo O Oyekan. Contribution of renal oxygenases to glycerol-induced acute renal failure in the rat. Journal of cardiovascular pharmacology. 2002 Jun; 39(6):834-41. doi: 10.1097/00005344-200206000-00008. [PMID: 12021577]
  • J M Catania, A R Parrish, A J Gandolfi. Toxicity of a sevoflurane degradation product incubated with rat liver and renal cortical slices. Drug and chemical toxicology. 2001 Nov; 24(4):347-57. doi: 10.1081/dct-100106264. [PMID: 11665648]