2-Methyl-6-phenyl-3,7-dihydroimidazo[1,2-a]pyrazin-3-one (BioDeep_00000173037)

   

human metabolite blood metabolite


代谢物信息卡片


2-Methyl-6-phenyl-3,7-dihydroimidazo(1,2-a)pyrazin-3-one

化学式: C13H11N3O (225.0902)
中文名称: CLA [化学发光试剂]
谱图信息: 最多检出来源 Homo sapiens(blood) 99.52%

分子结构信息

SMILES: CC1=C(N2C=C(N=CC2=N1)C3=CC=CC=C3)O
InChI: InChI=1S/C13H11N3O/c1-9-13(17)16-8-11(14-7-12(16)15-9)10-5-3-2-4-6-10/h2-8,17H,1H3

描述信息

D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D049408 - Luminescent Agents

同义名列表

7 个代谢物同义名

2-Methyl-6-phenyl-3,7-dihydroimidazo(1,2-a)pyrazin-3-one; 2-Methyl-6-phenyl-3,7-dihydroimidazo[1,2-a]pyrazin-3-one; 2-Methyl-6-phenylimidazo[1,2-a]pyrazin-3(7H)-one; 2-methyl-6-phenylimidazo[1,2-a]pyrazin-3-ol; Cypridina luciferin analog; CLA-phenyl; MPDHIP



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Yuka Kohda, Munekazu Gemba. Enhancement of protein kinase C activity and chemiluminescence intensity in mitochondria isolated from the kidney cortex of rats treated with cephaloridine. Biochemical pharmacology. 2002 Aug; 64(3):543-9. doi: 10.1016/s0006-2952(02)01216-9. [PMID: 12147306]
  • Y Tsutsui, Y Nakamura, S Yamaguchi, N Kawanaka, M Sato. Effects of zinc acexamate (NAS-501) on superoxide radicals and lipid peroxidation of rat gastric mucosa. Pharmacology. 1999 Apr; 58(4):209-19. doi: 10.1159/000028283. [PMID: 10077740]
  • K Kashima, N Sato, K Sato, H Shimizu, M Mori. Effect of epalrestat, an aldose reductase inhibitor, on the generation of oxygen-derived free radicals in neutrophils from streptozotocin-induced diabetic rats. Endocrinology. 1998 Aug; 139(8):3404-8. doi: 10.1210/endo.139.8.6152. [PMID: 9681489]
  • A Hirata, S Motojima, T Fukuda, S Makino. Damage to respiratory epithelium by guinea-pig eosinophils stimulated with IgG-coated Sepharose beads. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 1996 Jul; 26(7):848-58. doi: NULL. [PMID: 8842560]
  • M Uehara, N Sato. Impaired ability of neutrophils to produce oxygen-derived free radicals in patients with chronic liver disease and hepatocellular carcinoma. Hepatology (Baltimore, Md.). 1994 Aug; 20(2):326-30. doi: 10.1002/hep.1840200209. [PMID: 8045492]
  • M Kanashiro, T Matsubara, T Goto, N Sakamoto. Cypridina luciferin analog reduces the incidence of ischemia/reperfusion-induced ventricular fibrillation. Japanese journal of pharmacology. 1993 Sep; 63(1):47-52. doi: 10.1254/jjp.63.47. [PMID: 8271531]
  • S Koga, M Nakano. A high involvement of O2- possibly generated in inner membranes for iron-induced microsomal lipid peroxidation. Biochemical and biophysical research communications. 1992 Jul; 186(2):1087-93. doi: 10.1016/0006-291x(92)90858-i. [PMID: 1323282]
  • A Nishida, H Kimura, M Nakano. Assay for opsonin activity based on chemiluminescence of a Cypiridina luciferin analog. Biology of the neonate. 1992; 61(4):253-8. doi: 10.1159/000243751. [PMID: 1610955]