2,2'-Azobis(4-methoxy-2,4-dimethylvaleronitrile) (BioDeep_00000172909)
human metabolite blood metabolite
代谢物信息卡片
2-[2-(1-cyano-3-methoxy-1,3-dimethylbutyl)diazen-1-yl]-4-methoxy-2,4-dimethylpentanenitrile
化学式: C16H28N4O2 (308.2212148)
中文名称: 偶氮二甲氧基异庚腈
谱图信息:
最多检出来源 Homo sapiens(blood) 99.57%
分子结构信息
SMILES: CC(C)(CC(C)(C#N)N=NC(C)(CC(C)(C)OC)C#N)OC
InChI: InChI=1S/C16H28N4O2/c1-13(2,21-7)9-15(5,11-17)19-20-16(6,12-18)10-14(3,4)22-8/h9-10H2,1-8H3
描述信息
同义名列表
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Diane L McKay, C-Y Oliver Chen, Kyung-Jin Yeum, Nirupa R Matthan, Alice H Lichtenstein, Jeffrey B Blumberg. Chronic and acute effects of walnuts on antioxidant capacity and nutritional status in humans: a randomized, cross-over pilot study.
Nutrition journal.
2010 May; 9(?):21. doi:
10.1186/1475-2891-9-21. [PMID: 20462428] - Azzedine Mazari, Satoshi Iwamoto, Ryo Yamauchi. Effects of linoleic acid position in phosphatidylcholines and cholesterol addition on their rates of peroxidation in unilamellar liposomes.
Bioscience, biotechnology, and biochemistry.
2010; 74(5):1013-7. doi:
10.1271/bbb.90896. [PMID: 20460733] - Kyung-Jin Yeum, Giangiacomo Beretta, Norman I Krinsky, Robert M Russell, Giancarlo Aldini. Synergistic interactions of antioxidant nutrients in a biological model system.
Nutrition (Burbank, Los Angeles County, Calif.).
2009 Jul; 25(7-8):839-46. doi:
10.1016/j.nut.2009.01.011. [PMID: 19398299] - Hiroko Ogawa, Feng Hao Xu, Kazuo Uebaba, Hideki Origasa, Kazuo Kondoh, Masayuki Mikage. Antioxidative potentiality of a Kampo formulation measured by an ex vivo study.
Journal of alternative and complementary medicine (New York, N.Y.).
2009 Mar; 15(3):267-74. doi:
10.1089/acm.2007.0713. [PMID: 19292654] - Lei Li, C-Y Oliver Chen, Hye-Kyung Chun, Soo-Muk Cho, Ki-Moon Park, Yang Cha Lee-Kim, Jeffrey B Blumberg, Robert M Russell, Kyung-Jin Yeum. A fluorometric assay to determine antioxidant activity of both hydrophilic and lipophilic components in plant foods.
The Journal of nutritional biochemistry.
2009 Mar; 20(3):219-26. doi:
10.1016/j.jnutbio.2008.02.006. [PMID: 18602808] - Giangiacomo Beretta, Giancarlo Aldini, Roberto Maffei Facino, Robert M Russell, Norman I Krinsky, Kyung-Jin Yeum. Total antioxidant performance: a validated fluorescence assay for the measurement of plasma oxidizability.
Analytical biochemistry.
2006 Jul; 354(2):290-8. doi:
10.1016/j.ab.2006.04.001. [PMID: 16729959] - Keiko Ashidate, Mitsunobu Kawamura, Daigo Mimura, Hisako Tohda, Shigeru Miyazaki, Tamio Teramoto, Yorihiro Yamamoto, Yukio Hirata. Gentisic acid, an aspirin metabolite, inhibits oxidation of low-density lipoprotein and the formation of cholesterol ester hydroperoxides in human plasma.
European journal of pharmacology.
2005 Apr; 513(3):173-9. doi:
10.1016/j.ejphar.2005.03.012. [PMID: 15862799] - Midori Natsume, Naomi Osakabe, Akiko Yasuda, Seigo Baba, Takashi Tokunaga, Kazuo Kondo, Toshihiko Osawa, Junji Terao. In vitro antioxidative activity of (-)-epicatechin glucuronide metabolites present in human and rat plasma.
Free radical research.
2004 Dec; 38(12):1341-8. doi:
10.1080/10715760400022087. [PMID: 15763958] - Kyung-Jin Yeum, Giancarlo Aldini, Hae-Yun Chung, Norman I Krinsky, Robert M Russell. The activities of antioxidant nutrients in human plasma depend on the localization of attacking radical species.
The Journal of nutrition.
2003 Aug; 133(8):2688-91. doi:
10.1093/jn/133.8.2688. [PMID: 12888659] - Naomi Osakabe, Akiko Yasuda, Midori Natsume, Toshio Takizawa, Junji Terao, Kazuo Kondo. Catechins and their oligomers linked by C4 --> C8 bonds are major cacao polyphenols and protect low-density lipoprotein from oxidation in vitro.
Experimental biology and medicine (Maywood, N.J.).
2002 Jan; 227(1):51-6. doi:
10.1177/153537020222700109. [PMID: 11788784] - G Aldini, K J Yeum, R M Russell, N I Krinsky. A method to measure the oxidizability of both the aqueous and lipid compartments of plasma.
Free radical biology & medicine.
2001 Nov; 31(9):1043-50. doi:
10.1016/s0891-5849(01)00684-0. [PMID: 11677037] - V Raneva, H Shimasaki, Y Ishida, N Ueta, E Niki. Antioxidative activity of 3,4-dihydroxyphenylacetic acid and caffeic acid in rat plasma.
Lipids.
2001 Oct; 36(10):1111-6. doi:
10.1007/s11745-001-0821-6. [PMID: 11768155] - M Kawamura, S Miyazaki, T Teramoto, K Ashidate, H Thoda, N Ando, K Kaneko. Gemfibrozil metabolite inhibits in vitro low-density lipoprotein (LDL) oxidation and diminishes cytotoxicity induced by oxidized LDL.
Metabolism: clinical and experimental.
2000 Apr; 49(4):479-85. doi:
10.1016/s0026-0495(00)80012-8. [PMID: 10778872] - H Yamashita, A Nakamura, N Noguchi, E Niki, H Kühn. Oxidation of low density lipoprotein and plasma by 15-lipoxygenase and free radicals.
FEBS letters.
1999 Feb; 445(2-3):287-90. doi:
10.1016/s0014-5793(99)00137-4. [PMID: 10094474] - N Noguchi, H Yamashita, N Gotoh, Y Yamamoto, R Numano, E Niki. 2,2'-Azobis (4-methoxy-2,4-dimethylvaleronitrile), a new lipid-soluble azo initiator: application to oxidations of lipids and low-density lipoprotein in solution and in aqueous dispersions.
Free radical biology & medicine.
1998 Jan; 24(2):259-68. doi:
10.1016/s0891-5849(97)00230-x. [PMID: 9433901] - R Hirano, K Kondo, T Iwamoto, O Igarashi, H Itakura. Effects of antioxidants on the oxidative susceptibility of low-density lipoprotein.
Journal of nutritional science and vitaminology.
1997 Aug; 43(4):435-44. doi:
10.3177/jnsv.43.435. [PMID: 9328862]