Alnustone (BioDeep_00000017268)

 

Secondary id: BioDeep_00000617118

human metabolite PANOMIX_OTCML-2023


代谢物信息卡片


InChI=1/C19H18O/c20-19(16-15-18-11-5-2-6-12-18)14-8-7-13-17-9-3-1-4-10-17/h1-14H,15-16H2/b13-7+,14-8

化学式: C19H18O (262.1357578)
中文名称: 桤木酮
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 2.67%

分子结构信息

SMILES: C1=CC=C(C=C1)CCC(=O)C=CC=CC2=CC=CC=C2
InChI: InChI=1S/C19H18O/c20-19(16-15-18-11-5-2-6-12-18)14-8-7-13-17-9-3-1-4-10-17/h1-14H,15-16H2/b13-7+,14-8+

描述信息

Alnustone belongs to the class of organic compounds known as linear diarylheptanoids. These are diarylheptanoids with an open heptane chain. Alnustone is found in herbs and spices. Alnustone is a constituent of Curcuma xanthorrhiza (Java turmeric).
Alnustone is a diarylheptanoid.
Alnustone is a natural product found in Alnus pendula, Alpinia hainanensis, and other organisms with data available.
Alnustone, a non-phenolic diarylheptanoid found in herbs and spices, is a constituent of Alpiniae Katsumada. Alnustone displays anti-emetic and anti-inflammatory activities[1][2].
Alnustone, a non-phenolic diarylheptanoid found in herbs and spices, is a constituent of Alpiniae Katsumada. Alnustone displays anti-emetic and anti-inflammatory activities[1][2].

同义名列表

14 个代谢物同义名

InChI=1/C19H18O/c20-19(16-15-18-11-5-2-6-12-18)14-8-7-13-17-9-3-1-4-10-17/h1-14H,15-16H2/b13-7+,14-8; trans,trans-1,7-diphenyl-1,3-heptadien-5-one; (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one #; (4E,6E)-1,7-diphenyl-hepta-4,6-dien-3-one; (4E,6E)-1,7-diphenylhepta-4,6-dien-3-one; (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one; HEP-DIENE-ONE DER FR ALPINA KATSUMANDAI; (E,E)-1,7-Diphenyl-4,6-heptadien-3-one; 4,6-Heptadien-3-one, 1,7-diphenyl-; 1,7-diphenylhepta-4,6-dien-3-one; OWMJDOUOHDOUFG-FNCQTZNRSA-N; DAH-3-keto-4,6-dien; Alnustone; Alnusone



数据库引用编号

12 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yuan Lin, Kanjana Wongkrajang, Xiaofei Shen, Ping Wang, Zongyuan Zhou, Thipphawan Chuprajob, Nilubon Sornkaew, Na Yang, Lijuan Yang, Xiaoxia Lu, Ratchanaporn Chokchaisiri, Apichart Suksamrarn, Guolin Zhang, Fei Wang. Discovery of diarylheptanoids that activate α7 nAchR-JAK2-STAT3 signaling in macrophages with anti-inflammatory activity in vitro and in vivo. Bioorganic & medicinal chemistry. 2022 07; 66(?):116811. doi: 10.1016/j.bmc.2022.116811. [PMID: 35576655]
  • Corinne Vanucci-Bacqué, Florence Bedos-Belval. Anti-inflammatory activity of naturally occuring diarylheptanoids - A review. Bioorganic & medicinal chemistry. 2021 02; 31(?):115971. doi: 10.1016/j.bmc.2020.115971. [PMID: 33422907]
  • Barbara Gröblacher, Olaf Kunert, Franz Bucar. Compounds of Alpinia katsumadai as potential efflux inhibitors in Mycobacterium smegmatis. Bioorganic & medicinal chemistry. 2012 Apr; 20(8):2701-6. doi: 10.1016/j.bmc.2012.02.039. [PMID: 22459211]
  • Jian Su, Kittisak Sripanidkulchai, J Michael Wyss, Bungorn Sripanidkulchai. Curcuma comosa improves learning and memory function on ovariectomized rats in a long-term Morris water maze test. Journal of ethnopharmacology. 2010 Jul; 130(1):70-5. doi: 10.1016/j.jep.2010.04.012. [PMID: 20420894]