Articainic acid (BioDeep_00000172638)
human metabolite blood metabolite
代谢物信息卡片
化学式: C12H18N2O3S (270.1038078)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCNC(C)C(=O)NC1=C(SC=C1C)C(=O)O
InChI: InChI=1S/C12H18N2O3S/c1-4-5-13-8(3)11(15)14-9-7(2)6-18-10(9)12(16)17/h6,8,13H,4-5H2,1-3H3,(H,14,15)(H,16,17)
数据库引用编号
分类词条
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
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Plant Reactome(0)
INOH(0)
PlantCyc(0)
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1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- D Venkatachalam, J P Chambers, K Kongara, P Singh. Pharmacokinetics of articaine hydrochloride and its metabolite articainic acid after subcutaneous administration in red deer (Cervus elaphus).
New Zealand veterinary journal.
2018 Jan; 66(1):16-20. doi:
10.1080/00480169.2017.1391141
. [PMID: 29020878] - Chen Song, Henning Lygre, Willy Nerdal. Articaine interaction with DSPC bilayer: a 13C and 31P solid-state NMR study.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2008 Apr; 33(4-5):399-408. doi:
10.1016/j.ejps.2008.01.010
. [PMID: 18343644] - K Richter, R Oertel. Solid-phase extraction and high-performance liquid chromatographic determination of articainic and its metabolite articainic acid in human serum.
Journal of chromatography. B, Biomedical sciences and applications.
1999 Mar; 724(1):109-15. doi:
10.1016/s0378-4347(98)00563-5
. [PMID: 10202963] - R Oertel, K Richter. Plasma protein binding of the local anaesthetic drug articaine and its metabolite articainic acid.
Die Pharmazie.
1998 Sep; 53(9):646-7. doi:
NULL
. [PMID: 9770216] - T B Vree, M A Simon, M J Gielen, L H Booij. Regional metabolism of articaine in 10 patients undergoing intravenous regional anaesthesia during day case surgery.
British journal of clinical pharmacology.
1997 Jul; 44(1):29-34. doi:
10.1046/j.1365-2125.1997.00621.x
. [PMID: 9241093] - R Oertel, A Berndt, W Kirch. Saturable in vitro metabolism of articaine by serum esterases. Does it contribute to the persistence of the local anesthetic effect?.
Regional anesthesia.
1996 Nov; 21(6):576-81. doi:
NULL
. [PMID: 8956396] - R Oertel, K Richter, K Weile, T Gramatté, A Berndt, K Feller. A simple method for the determination of articaine and its metabolite articainic acid in dentistry: application to a comparison of articaine and lidocaine concentrations in alveolus blood.
Methods and findings in experimental and clinical pharmacology.
1993 Oct; 15(8):541-7. doi:
NULL
. [PMID: 8309318] - G E van Oss, T B Vree, A M Baars, E F Termond, L H Booij. Pharmacokinetics, metabolism, and renal excretion of articaine and its metabolite articainic acid in patients after epidural administration.
European journal of anaesthesiology.
1989 Jan; 6(1):49-56. doi:
NULL
. [PMID: 2714265] - T B Vree, A M Baars, G E van Oss, L H Booij. High-performance liquid chromatography and preliminary pharmacokinetics of articaine and its 2-carboxy metabolite in human serum and urine.
Journal of chromatography.
1988 Feb; 424(2):440-4. doi:
10.1016/s0378-4347(00)81126-3
. [PMID: 3372637]