Eudesmic acid (BioDeep_00000017248)

 

Secondary id: BioDeep_00000600243

human metabolite PANOMIX_OTCML-2023


代谢物信息卡片


Trimebutine Imp. B (EP); Trimethoprim Imp. J (EP); 3,4,5-Trimethoxybenzoic Acid; Trimebutine Maleate Impurity B; Trimethoprim Impurity J

化学式: C10H12O5 (212.0685)
中文名称: 3,4,5-三甲氧基苯甲酸
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 5.47%

分子结构信息

SMILES: c1(c(cc(cc1OC)C(=O)O)OC)OC
InChI: InChI=1S/C10H12O5/c1-13-7-4-6(10(11)12)5-8(14-2)9(7)15-3/h4-5H,1-3H3,(H,11,12)

描述信息

3,4,5-trimethoxybenzoic acid is a benzoic acid derivative carrying 3-, 4- and 5-methoxy substituents. It has a role as a plant metabolite, a human xenobiotic metabolite and a human urinary metabolite. It is a member of benzoic acids and a member of methoxybenzenes. It is functionally related to a benzoic acid. It is a conjugate acid of a 3,4,5-trimethoxybenzoate.
3,4,5-Trimethoxybenzoic acid is a natural product found in Verbesina myriocephala, Engelhardia roxburghiana, and other organisms with data available.
Eudesmic acid is found in olive. Eudesmic acid is isolated from eucalyptus oil etc.
A benzoic acid derivative carrying 3-, 4- and 5-methoxy substituents.
Isolated from eucalyptus oil etc. Eudesmic acid is found in olive.
3,4,5-Trimethoxybenzoic acid (Eudesmic acid;Trimethylgallic Acid) is a benzoic acid derivative. A building block in medicine and organic synthesis.
3,4,5-Trimethoxybenzoic acid (Eudesmic acid;Trimethylgallic Acid) is a benzoic acid derivative. A building block in medicine and organic synthesis.

同义名列表

47 个代谢物同义名

Trimebutine Imp. B (EP); Trimethoprim Imp. J (EP); 3,4,5-Trimethoxybenzoic Acid; Trimebutine Maleate Impurity B; Trimethoprim Impurity J; Eudesmic Acid; 3,4,5-Trimethoxybenzoic acid; Trimethylgallic acid; 5-methoxy-veratric acid; Gallic acid trimethyl ether; Hydrogen(T-4)-bis[3,5-bis(1,1-dimethylethyl)-2-hydroxybenzoato(2-)-O1, O2]aluminate(1-); 3,4,5-Trimethoxybenzoic acid, Vetec(TM) reagent grade, 99\\%; 3,4,5-Trimethoxybenzoic acid, ReagentPlus(R), 99\\%; TRIMEBUTINE MALEATE IMPURITY B [EP IMPURITY]; 3,4,5-trimethoxybenzoic acid, potassium salt; 3,4,5-trimethoxybenzoic acid, sodium salt; TRIMETHOPRIM IMPURITY J [EP IMPURITY]; Benzoic acid, 3,4,5-trimethoxy-; 3,4,5 trimethoxy benzoic acid; 3,4,5-trimethoxy-benzoic acid; 3,4,5-Trimethoxy Benzoic Acid; Benzoic acid,4,5-trimethoxy-; 3,4,5-Trimethoxybenzoic acid; Gallic acid trimethyl ether; Trimethoprim EP Impurity J; 3,5-Trimethoxybenzoic acid; Veratric acid, 5-methoxy-; 3,4,5-Trimethoxybenzoate; Gallate trimethyl ether; 5-methoxy-veratric acid; Tri-O-methylgallic acid; Trimethylgallic acid; Trimethylgallicacid; 5-Methoxy-veratrate; Tri-O-methylgallate; Spectrum3_000260; Spectrum5_000409; Trimethylgallate; Spectrum2_000791; Spectrum4_001625; UNII-V5C9H0SC9F; DivK1c_007015; Oprea1_180796; eudesmic acid; KBio1_001959; KBio2_000502; KBio2_003070; KBio2_005638; KBio3_001180; V5C9H0SC9F; AI3-21153; Eudesmate; Gallic; H5A; 3,4,5-Trimethoxybenzoic acid



数据库引用编号

14 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

17 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Thomas A K Prescott, Barry Panaretou, Nigel C Veitch, Monique S J Simmonds. A yeast chemical genetics approach identifies the compound 3,4,5-trimethoxybenzyl isothiocyanate as a calcineurin inhibitor. FEBS letters. 2014 Jan; 588(3):455-8. doi: 10.1016/j.febslet.2013.12.006. [PMID: 24374339]
  • Tian-Shan Wang, You-Ping Luo, Jing Wang, Meng-Xiong He, Ming-Guo Zhong, Ying Li, Xiao-Ping Song. (+)-rumphiin and polyalthurea, new compounds from the stems of Polyalthia rumphii. Natural product communications. 2013 Oct; 8(10):1427-9. doi: . [PMID: 24354193]
  • Vikas Srivastava, Arvind Singh Negi, P V Ajayakumar, Shamshad A Khan, Suchitra Banerjee. Atropa belladonna hairy roots: orchestration of concurrent oxidation and reduction reactions for biotransformation of carbonyl compounds. Applied biochemistry and biotechnology. 2012 Mar; 166(6):1401-8. doi: 10.1007/s12010-011-9533-3. [PMID: 22246731]
  • Zhi-Gang Yang, Liu-Nan Jia, Yan Shen, Atsuko Ohmura, Susumu Kitanaka. Inhibitory effects of constituents from Euphorbia lunulata on differentiation of 3T3-L1 cells and nitric oxide production in RAW264.7 cells. Molecules (Basel, Switzerland). 2011 Sep; 16(10):8305-18. doi: 10.3390/molecules16108305. [PMID: 21959301]
  • Shaheen Faizi, Shahina Fayyaz, Samina Bano, Erum Yawar Iqbal, Lubna, Humaira Siddiqi, Aneela Naz. Isolation of nematicidal compounds from Tagetes patula L. yellow flowers: structure-activity relationship studies against cyst nematode Heterodera zeae infective stage larvae. Journal of agricultural and food chemistry. 2011 Sep; 59(17):9080-93. doi: 10.1021/jf201611b. [PMID: 21780738]
  • Pedro Angelo Silva, Reiaz Ul-Rehman, Cláudia Rato, Gian-Pietro Di Sansebastiano, Rui Malhó. Asymmetric localization of Arabidopsis SYP124 syntaxin at the pollen tube apical and sub-apical zones is involved in tip growth. BMC plant biology. 2010 Aug; 10(?):179. doi: 10.1186/1471-2229-10-179. [PMID: 20718953]
  • Jeong Hee Han, Kyung-Ah Kim, Amin Shah, Byung Hyun Park, Woo Hyun Park, Suhn Hee Kim. Regulation of renin release by connexin 43 in As 4.1 cell line. Peptides. 2010 May; 31(5):899-902. doi: 10.1016/j.peptides.2010.02.014. [PMID: 20188775]
  • Virginia Claudia da Silva, Mário Geraldo de Carvalho, Aline Nogueira Alves. Chemical constituents from leaves of Palicourea coriacea (Rubiaceae). Journal of natural medicines. 2008 Jul; 62(3):356-7. doi: 10.1007/s11418-008-0227-2. [PMID: 18404310]
  • Yan-Jun Hu, Hua-Guang Yu, Jia-Xin Dong, Xi Yang, Yi Liu. Spectroscopic studies on the interaction between 3,4,5-trimethoxybenzoic acid and bovine serum albumin. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2006 Nov; 65(3-4):988-92. doi: 10.1016/j.saa.2006.02.004. [PMID: 16679051]
  • Klaas G J Nierop, Caroline M Preston, Joeri Kaal. Thermally assisted hydrolysis and methylation of purified tannins from plants. Analytical chemistry. 2005 Sep; 77(17):5604-14. doi: 10.1021/ac050564r. [PMID: 16131072]
  • Di Wu, XiangMei Chen, DengFu Guo, Quan Hong, Bo Fu, Rui Ding, LiFang Yu, Kai Hou, Zhe Feng, XiaoJie Zhang, JianZhong Wang. Knockdown of fibronectin induces mitochondria-dependent apoptosis in rat mesangial cells. Journal of the American Society of Nephrology : JASN. 2005 Mar; 16(3):646-57. doi: 10.1681/asn.2004060445. [PMID: 15677310]
  • Satyanarayana Sreemantula, Krishna M Boini, Srinivas Nammi. Reserpine methonitrate, a novel quaternary analogue of reserpine augments urinary excretion of VMA and 5-HIAA without affecting HVA in rats. BMC pharmacology. 2004 Nov; 4(?):30. doi: 10.1186/1471-2210-4-30. [PMID: 15546495]
  • Hongyun Wang, Hui Zhou, Shingo Horimoto, Ji Jiang, Tsuyoshi Mayumi, Pei Hu. Quantitative determination of trimebutine maleate and its three metabolites in human plasma by liquid chromatography-tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2002 Nov; 779(2):173-87. doi: 10.1016/s1570-0232(02)00369-0. [PMID: 12361732]
  • Qiuwen Mi, Baoliang Cui, Daniel Chávez, Heebyung Chai, Haiyuan Zhu, Geoffrey A Cordell, Sam Hedayat, A Douglas Kinghorn, John M Pezzuto. Characterization of tropane alkaloid aromatic esters that reverse the multidrug-resistance phenotype. Anticancer research. 2002 May; 22(3):1385-97. doi: ". [PMID: 12168815]
  • J Leonova, T Thorlin, N D Aberg, P S Eriksson, L Rönnbäck, E Hansson. Endothelin-1 decreases glutamate uptake in primary cultured rat astrocytes. American journal of physiology. Cell physiology. 2001 Nov; 281(5):C1495-503. doi: 10.1152/ajpcell.2001.281.5.c1495. [PMID: 11600412]
  • E Pogonowska-Wala. Craviten hydrolysis in plasma in vitro. Polish journal of pharmacology and pharmacy. 1981 Oct; 33(3):365-71. doi: NULL. [PMID: 7322949]
  • J Modestin, A Petrin. [Correlation between plasma concentration and clinical effect of neuroleptics and antidepressants]. International journal of clinical pharmacology and biopharmacy. 1976 Jan; 13(1):11-21. doi: NULL. [PMID: 2561]