2H-1,4-Benzothiazine (BioDeep_00000172462)

   

human metabolite blood metabolite


代谢物信息卡片


2H-1,4-Benzothiazine

化学式: C8H7NS (149.0299182)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1C=NC2=CC=CC=C2S1
InChI: InChI=1S/C8H7NS/c1-2-4-8-7(3-1)9-5-6-10-8/h1-5H,6H2

描述信息

同义名列表

3 个代谢物同义名

2H-1,4-Benzothiazine; 1,4-Benzothiazine; benzothiazine



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Andleeb Amin, Zubaid-Ul- Khazir, Arfa Ji, Basharat Ahmad Bhat, Dar Murtaza, Aaqib A Hurrah, Imtiyaz A Bhat, Shaheena Parveen, Syed Nisar, Praveen Kumar Sharma. Anti-lung Cancer Activity of Synthesized Substituted 1,4-Benzothiazines: An Insight from Molecular Docking and Experimental Studies. Anti-cancer agents in medicinal chemistry. 2024; 24(5):358-371. doi: 10.2174/0118715206276737231103114924. [PMID: 37957911]
  • Maria G Katselou, Alexios N Matralis, Angeliki P Kourounakis. Developing potential agents against atherosclerosis: Design, synthesis and pharmacological evaluation of novel dual inhibitors of oxidative stress and Squalene Synthase activity. European journal of medicinal chemistry. 2017 Sep; 138(?):748-760. doi: 10.1016/j.ejmech.2017.06.042. [PMID: 28728107]
  • Alexios N Matralis, Maria G Katselou, Anastasios Nikitakis, Angeliki P Kourounakis. Novel benzoxazine and benzothiazine derivatives as multifunctional antihyperlipidemic agents. Journal of medicinal chemistry. 2011 Aug; 54(15):5583-91. doi: 10.1021/jm200763k. [PMID: 21702499]
  • M Kumar, Kshitija Sharma, R M Samarth, A Kumar. Synthesis and antioxidant activity of quinolinobenzothiazinones. European journal of medicinal chemistry. 2010 Oct; 45(10):4467-72. doi: 10.1016/j.ejmech.2010.07.006. [PMID: 20691512]
  • Chi Chen, Kristopher W Krausz, Jeffrey R Idle, Frank J Gonzalez. Identification of novel toxicity-associated metabolites by metabolomics and mass isotopomer analysis of acetaminophen metabolism in wild-type and Cyp2e1-null mice. The Journal of biological chemistry. 2008 Feb; 283(8):4543-59. doi: 10.1074/jbc.m706299200. [PMID: 18093979]
  • Fausto Schiaffella, Antonio Macchiarulo, Lara Milanese, Anna Vecchiarelli, Renata Fringuelli. Novel ketoconazole analogues based on the replacement of 2,4-dichlorophenyl group with 1,4-benzothiazine moiety: design, synthesis, and microbiological evaluation. Bioorganic & medicinal chemistry. 2006 Aug; 14(15):5196-203. doi: 10.1016/j.bmc.2006.04.004. [PMID: 16650767]
  • Akihiko Takasaki, Dzeneta Nezirević, Kerstin Arstrand, Kazumasa Wakamatsu, Shosuke Ito, Bertil Kågedal. HPLC analysis of pheomelanin degradation products in human urine. Pigment cell research. 2003 Oct; 16(5):480-6. doi: 10.1034/j.1600-0749.2003.00086.x. [PMID: 12950724]
  • Renata Fringuelli, Donatella Pietrella, Fausto Schiaffella, Alessia Guarraci, Stefano Perito, Francesco Bistoni, Anna Vecchiarelli. Anti-Candida albicans properties of novel benzoxazine analogues. Bioorganic & medicinal chemistry. 2002 Jun; 10(6):1681-6. doi: 10.1016/s0968-0896(02)00038-x. [PMID: 11937326]