1,3-Bis(4-nitrophenyl)urea (BioDeep_00000172425)
human metabolite blood metabolite Volatile Flavor Compounds
代谢物信息卡片
urea, N,N-bis(4-nitrophenyl)-
化学式: C13H10N4O5 (302.065117)
中文名称: 1,3-二(4-硝基苯)脲, 尼卡巴嗪, 1,3-双（4-硝基苯基）脲
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC(=CC=C1NC(=O)NC2=CC=C(C=C2)[N+](=O)[O-])[N+](=O)[O-]
InChI: InChI=1S/C13H10N4O5/c18-13(14-9-1-5-11(6-2-9)16(19)20)15-10-3-7-12(8-4-10)17(21)22/h1-8H,(H2,14,15,18)
数据库引用编号
分类词条
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
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1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Sharon L Brunelle, Robert A LaBudde, Kimberly Lombardi, Clive Ward. Determination and Identification of Nicarbazin, Measured as 4,4'-Dinitrocarbanilide (DNC), in Chicken Tissues by Liquid Chromatography With Tandem Mass Spectrometry: Final Action 2013.07.
Journal of AOAC International.
2022 Jun; 105(4):1008-1016. doi:
10.1093/jaoacint/qsac011. [PMID: 35108390] - Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - Mark R Coleman, John M Rodewald, Sharon L Brunelle, Maria Nelson, Lauryn Bailey, Thomas J Burnett. Determination and confirmation of nicarbazin, measured as 4,4-dinitrocarbanilide (DNC), in chicken tissues by liquid chromatography with tandem mass spectrometry: First Action 2013.07.
Journal of AOAC International.
2014 Mar; 97(2):630-40. doi:
10.5740/jaoacint.13-197. [PMID: 24830177] - Kathleen A Fagerstone, Lowell A Miller, Gary Killian, Christi A Yoder. Review of issues concerning the use of reproductive inhibitors, with particular emphasis on resolving human-wildlife conflicts in North America.
Integrative zoology.
2010 Mar; 5(1):15-30. doi:
10.1111/j.1749-4877.2010.00185.x. [PMID: 21392318] - John Mitchell. Small molecule immunosensing using surface plasmon resonance.
Sensors (Basel, Switzerland).
2010; 10(8):7323-46. doi:
10.3390/s100807323. [PMID: 22163605] - Gabriela Gómez-Verduzco, Arturo Cortes-Cuevas, Carlos López-Coello, Ernesto Avila-González, Gerardo M Nava. Dietary supplementation of mannan-oligosaccharide enhances neonatal immune responses in chickens during natural exposure to Eimeria spp.
Acta veterinaria Scandinavica.
2009 Mar; 51(?):11. doi:
10.1186/1751-0147-51-11. [PMID: 19298670] - C A Yoder, J K Graham, L A Miller, K S Bynum, J J Johnston, M J Goodall. Effect of method of delivering nicarbazin to mallards on plasma 4,4'-dinitrocarbanilide levels and reproduction.
Poultry science.
2006 Aug; 85(8):1442-8. doi:
10.1093/ps/85.8.1442. [PMID: 16903476] - C A Yoder, J K Graham, L A Miller, K S Bynum, J J Johnston, M J Goodall. Evaluation of nicarbazin as a potential waterfowl contraceptive using mallards as a model.
Poultry science.
2006 Jul; 85(7):1275-84. doi:
10.1093/ps/85.7.1275. [PMID: 16830869] - C A Yoder, J K Graham, L A Miller. Molecular effects of nicarbazin on avian reproduction.
Poultry science.
2006 Jul; 85(7):1285-93. doi:
10.1093/ps/85.7.1285. [PMID: 16830870] - C A Yoder, L A Miller, K S Bynum. Comparison of nicarbazin absorption in chickens, mallards, and Canada geese.
Poultry science.
2005 Sep; 84(9):1491-4. doi:
10.1093/ps/84.9.1491. [PMID: 16206573] - G F Mathis, R Froyman, T Kennedy. Coccidiosis control by administering toltrazuril in the drinking water for a 2-day period.
Veterinary parasitology.
2004 May; 121(1-2):1-9. doi:
10.1016/j.vetpar.2004.02.020. [PMID: 15110398] - Thomas M Primus, Dennis J Kohler, Margaret A Goodall, Christi Yoder, Thomas Mathies, Lowell Miller, John J Johnston, Kurt Vercauteren. Liquid chromatographic determination of 4,4'-dinitrocarbanilide, the active component of the infertility agent nicarbazin, in chicken, duck, goose, and snake eggs.
Journal of AOAC International.
2003 Nov; 86(6):1144-8. doi:
10.1093/jaoac/86.6.1144. [PMID: 14979695] - Lisa Connolly, Terence L Fodey, Steven R H Crooks, Christopher T Elliott. The production and characterisation of an antibody to detect the coccidiostat toltrazuril and its metabolite ponazuril.
The Analyst.
2003 May; 128(5):459-61. doi:
10.1039/b301898a. [PMID: 12790197] - Jerome C Hurley, John J Johnston. Poly(methyl methacrylate) synthetic grit formulations sustain the delivery of nicarbazin, a contraceptive agent, in pest waterfowl.
Journal of controlled release : official journal of the Controlled Release Society.
2002 Dec; 85(1-3):135-43. doi:
10.1016/s0168-3659(02)00285-7. [PMID: 12480319] - Lisa Connolly, Terence L Fodey, Steven R H Crooks, Philippe Delahaut, Christopher T Elliott. The production and characterisation of dinitrocarbanilide antibodies raised using antigen mimics.
Journal of immunological methods.
2002 Jun; 264(1-2):45-51. doi:
10.1016/s0022-1759(02)00040-6. [PMID: 12191508] - R B Williams, L Gobbi. Comparison of an attenuated anticoccidial vaccine and an anticoccidial drug programme in commercial broiler chickens in Italy.
Avian pathology : journal of the W.V.P.A.
2002 Jun; 31(3):253-65. doi:
10.1080/03079450220136567a. [PMID: 12400552] - John J Johnston, Walter M Britton, Alexander MacDonald, Thomas M Primus, Margaret J Goodal, Christi A Yoder, Lowell A Miller, Kathleen A Fagerstone. Quantification of plasma and egg 4,4'-dinitrocarbanilide (DNC) residues for the efficient development of a nicarbazin-based contraceptive for pest waterfowl.
Pest management science.
2002 Feb; 58(2):197-202. doi:
10.1002/ps.439. [PMID: 11852646] - T M Primus, D J Kohler, M A Goodall, C Yoder, D Griffin, L Miller, J J Johnston. Determination of 4,4'-dinitrocarbanilide (DNC), the active component of the antifertility agent nicarbazin, in chicken, duck, and goose plasma.
Journal of agricultural and food chemistry.
2001 Aug; 49(8):3589-93. doi:
10.1021/jf0102463. [PMID: 11513633]