1,2-Dioxolane (BioDeep_00000172376)

   

human metabolite blood metabolite


代谢物信息卡片


1,2-Dioxolane

化学式: C3H6O2 (74.0367776)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1COOC1
InChI: InChI=1S/C3H6O2/c1-2-4-5-3-1/h1-3H2

描述信息

同义名列表

2 个代谢物同义名

1,2-Dioxolane; dioxolane



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Chi-Chi Peng, Wei Shi, Justin D Lutz, Kent L Kunze, Jun O Liu, Wendel L Nelson, Nina Isoherranen. Stereospecific metabolism of itraconazole by CYP3A4: dioxolane ring scission of azole antifungals. Drug metabolism and disposition: the biological fate of chemicals. 2012 Mar; 40(3):426-35. doi: 10.1124/dmd.111.042739. [PMID: 22106171]
  • Thomas Hartwig, Claudia Corvalan, Norman B Best, Joshua S Budka, Jia-Ying Zhu, Sunghwa Choe, Burkhard Schulz. Propiconazole is a specific and accessible brassinosteroid (BR) biosynthesis inhibitor for Arabidopsis and maize. PloS one. 2012; 7(5):e36625. doi: 10.1371/journal.pone.0036625. [PMID: 22590578]
  • Shinsaku Ito, Nobutaka Kitahata, Mikihisa Umehara, Atsushi Hanada, Atsutaka Kato, Kotomi Ueno, Kiyoshi Mashiguchi, Junko Kyozuka, Koichi Yoneyama, Shinjiro Yamaguchi, Tadao Asami. A new lead chemical for strigolactone biosynthesis inhibitors. Plant & cell physiology. 2010 Jul; 51(7):1143-50. doi: 10.1093/pcp/pcq077. [PMID: 20522488]
  • John H Grabber, Paul F Schatz, Hoon Kim, Fachuang Lu, John Ralph. Identifying new lignin bioengineering targets: 1. Monolignol-substitute impacts on lignin formation and cell wall fermentability. BMC plant biology. 2010 Jun; 10(?):114. doi: 10.1186/1471-2229-10-114. [PMID: 20565789]
  • L Jackson Roberts, Ginger L Milne. Isoprostanes. Journal of lipid research. 2009 Apr; 50 Suppl(?):S219-23. doi: 10.1194/jlr.r800037-jlr200. [PMID: 18957694]
  • Carmony L Hartwig, Andrew S Rosenthal, John D'Angelo, Carol E Griffin, Gary H Posner, Roland A Cooper. Accumulation of artemisinin trioxane derivatives within neutral lipids of Plasmodium falciparum malaria parasites is endoperoxide-dependent. Biochemical pharmacology. 2009 Feb; 77(3):322-36. doi: 10.1016/j.bcp.2008.10.015. [PMID: 19022224]
  • Shasikala Narayan, Debra L Wyatt, David S Crumrine, Samuel Cukierman. Proton transfer in water wires in proteins: modulation by local constraint and polarity in gramicidin a channels. Biophysical journal. 2007 Sep; 93(5):1571-9. doi: 10.1529/biophysj.107.109231. [PMID: 17496018]
  • Carlton K K Lee, Eric K Rowinsky, Jing Li, Francis Giles, Malcolm J Moore, Manuel Hidalgo, Edmund Capparelli, Jacques Jolivet, Sharyn D Baker. Population pharmacokinetics of troxacitabine, a novel dioxolane nucleoside analogue. Clinical cancer research : an official journal of the American Association for Cancer Research. 2006 Apr; 12(7 Pt 1):2158-65. doi: 10.1158/1078-0432.ccr-05-2249. [PMID: 16609029]
  • Ching-Hsing Yu, Samuel Cukierman, Régis Pomès. Theoretical study of the structure and dynamic fluctuations of dioxolane-linked gramicidin channels. Biophysical journal. 2003 Feb; 84(2 Pt 1):816-31. doi: 10.1016/s0006-3495(03)74901-7. [PMID: 12547766]
  • Anatoly Chernyshev, Samuel Cukierman. Thermodynamic view of activation energies of proton transfer in various gramicidin A channels. Biophysical journal. 2002 Jan; 82(1 Pt 1):182-92. doi: 10.1016/s0006-3495(02)75385-x. [PMID: 11751307]
  • K M Armstrong, E P Quigley, P Quigley, D S Crumrine, S Cukierman. Covalently linked gramicidin channels: effects of linker hydrophobicity and alkaline metals on different stereoisomers. Biophysical journal. 2001 Apr; 80(4):1810-8. doi: 10.1016/s0006-3495(01)76151-6. [PMID: 11259294]
  • G L Kennedy, A J O'Neill, R Valentine. Inhalation toxicity of Dioxole and Dioxolane compounds in the rat. Drug and chemical toxicology. 2001 Feb; 24(1):1-17. doi: 10.1081/dct-100103082. [PMID: 11307631]
  • F J Giles, J E Cortes, S D Baker, D A Thomas, S O'Brien, T L Smith, M Beran, C Bivins, J Jolivet, H M Kantarjian. Troxacitabine, a novel dioxolane nucleoside analog, has activity in patients with advanced leukemia. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2001 Feb; 19(3):762-71. doi: 10.1200/jco.2001.19.3.762. [PMID: 11157029]