1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (BioDeep_00000172374)
human metabolite blood metabolite
代谢物信息卡片
(2-aminoethoxy)[2,3-bis(octadec-9-enoyloxy)propoxy]phosphinic acid
化学式: C41H78NO8P (743.5465)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 97.92%
分子结构信息
SMILES: CCCCCCCCC=CCCCCCCCC(=O)OCC(COP(O)(=O)OCCN)OC(=O)CCCCCCCC=CCCCCCCCC
InChI: InChI=1S/C41H78NO8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(43)47-37-39(38-49-51(45,46)48-36-35-42)50-41(44)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h17-20,39H,3-16,21-38,42H2,1-2H3,(H,45,46)
描述信息
同义名列表
11 个代谢物同义名
(2-aminoethoxy)[2,3-bis(octadec-9-enoyloxy)propoxy]phosphinic acid; 2-aminoethoxy(2,3-bis(octadec-9-enoyloxy)propoxy)phosphinic acid; 1-2-Di-(9-octadecenoyl)-sn-glycero-3-phosphoethethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine; 1,2-Dioleoylglycero-3-phosphoethanolamine; 1,2-Dielaidoylphosphatidylethanolamine; 1,2-Dioleoylphosphatidylethanolamine; Dioleoyl cephalin; Lipofectin; 1-2-DOPE; 1,2-DOPE
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
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Journal of drug targeting.
2006 Sep; 14(8):576-82. doi:
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Chemistry and physics of lipids.
2006 Jul; 142(1-2):118-27. doi:
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Acta biomaterialia.
2006 Mar; 2(2):207-12. doi:
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Gene therapy.
2005 Oct; 12(19):1417-23. doi:
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Molecular membrane biology.
2005 Jul; 22(4):303-11. doi:
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Biophysical journal.
2005 May; 88(5):3368-80. doi:
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Oligonucleotides.
2005; 15(1):12-22. doi:
10.1089/oli.2005.15.12. [PMID: 15788897] - Haike Dannowski, Jürgen Bednarz, Regina Reszka, Katrin Engelmann, Uwe Pleyer. Lipid-mediated gene transfer of acidic fibroblast growth factor into human corneal endothelial cells.
Experimental eye research.
2005 Jan; 80(1):93-101. doi:
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Journal of drug targeting.
2004 May; 12(4):185-93. doi:
10.1080/10611860410001724459. [PMID: 15506167] - Qing-Hai Meng, Danielle Robinson, R Gisli Jenkins, Robin J McAnulty, Stephen L Hart. Efficient transfection of non-proliferating human airway epithelial cells with a synthetic vector system.
The journal of gene medicine.
2004 Feb; 6(2):210-21. doi:
10.1002/jgm.483. [PMID: 14978774] - Robert E White, Richard Wade-Martins, Stephen L Hart, Jon Frampton, Bryan Huey, Ami Desai-Mehta, Karen M Cerosaletti, Patrick Concannon, Michael R James. Functional delivery of large genomic DNA to human cells with a peptide-lipid vector.
The journal of gene medicine.
2003 Oct; 5(10):883-892. doi:
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Journal of drug targeting.
2003 Jul; 11(6):311-23. doi:
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Biochimica et biophysica acta.
2003 Apr; 1611(1-2):204-16. doi:
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Journal of lipid research.
2003 Mar; 44(3):567-75. doi:
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Biophysical journal.
2002 May; 82(5):2504-10. doi:
10.1016/s0006-3495(02)75593-8. [PMID: 11964238] - Naijie Jing, Weijun Xiong, Yongli Guan, Luke Pallansch, Shimei Wang. Potassium-dependent folding: a key to intracellular delivery of G-quartet oligonucleotides as HIV inhibitors.
Biochemistry.
2002 Apr; 41(17):5397-403. doi:
10.1021/bi0120401. [PMID: 11969399] - Stefanie Marx, Jörg Schilling, Erich Sackmann, Robijn Bruinsma. Helfrich repulsion and dynamical phase separation of multicomponent lipid bilayers.
Physical review letters.
2002 Apr; 88(13):138102. doi:
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Biochimica et biophysica acta.
2002 Feb; 1559(2):87-95. doi:
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Chemistry (Weinheim an der Bergstrasse, Germany).
2002 Feb; 8(4):900-9. doi:
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Cellular & molecular biology letters.
2002; 7(1):19-29. doi:
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Biochimica et biophysica acta.
2001 Dec; 1515(2):189-201. doi:
10.1016/s0005-2736(01)00413-8. [PMID: 11718674] - Y Wu, G L Fletcher. Efficacy of antifreeze protein types in protecting liposome membrane integrity depends on phospholipid class.
Biochimica et biophysica acta.
2001 Nov; 1524(1):11-6. doi:
10.1016/s0304-4165(00)00134-3. [PMID: 11078953] - T Ahn, J S Kim, B C Lee, C H Yun. Effects of lipids on the interaction of SecA with model membranes.
Archives of biochemistry and biophysics.
2001 Nov; 395(1):14-20. doi:
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Biochimica et biophysica acta.
2001 Sep; 1514(1):100-16. doi:
10.1016/s0005-2736(01)00372-8. [PMID: 11513808] - V M Aguilella, S M Bezrukov. Alamethicin channel conductance modified by lipid charge.
European biophysics journal : EBJ.
2001 Aug; 30(4):233-41. doi:
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Vaccine.
2001 Apr; 19(23-24):3301-10. doi:
10.1016/s0264-410x(00)00432-1. [PMID: 11312029] - S Kaiser, M Toborek. Liposome-mediated high-efficiency transfection of human endothelial cells.
Journal of vascular research.
2001 Mar; 38(2):133-43. doi:
10.1159/000051040. [PMID: 11316949] - J E Baatz, Y Zou, T R Korfhagen. Inhibitory effects of tumor necrosis factor-alpha on cationic lipid-mediated gene delivery to airway cells in vitro.
Biochimica et biophysica acta.
2001 Feb; 1535(2):100-9. doi:
10.1016/s0925-4439(00)00084-3. [PMID: 11341998] - S Obika, W Yu, A Shimoyama, T Uneda, K Miyashita, T Doi, T Imanishi. Symmetrical cationic triglycerides: an efficient synthesis and application to gene transfer.
Bioorganic & medicinal chemistry.
2001 Feb; 9(2):245-54. doi:
10.1016/s0968-0896(00)00242-x. [PMID: 11249117] - G G McManus, G W Buchanan, H C Jarrell, R M Epand, R F Epand, J J Cheetham. Membrane perturbing properties of sucrose polyesters.
Chemistry and physics of lipids.
2001 Feb; 109(2):185-202. doi:
10.1016/s0009-3084(00)00222-x. [PMID: 11269937] - F Liu, R N Lewis, R S Hodges, R N McElhaney. A differential scanning calorimetric and 31P NMR spectroscopic study of the effect of transmembrane alpha-helical peptides on the lamellar-reversed hexagonal phase transition of phosphatidylethanolamine model membranes.
Biochemistry.
2001 Jan; 40(3):760-8. doi:
10.1021/bi001942j. [PMID: 11170393] - S Zellmer, F Gaunitz, J Salvetter, A Surovoy, D Reissig, R Gebhardt. Long-term expression of foreign genes in normal human epidermal keratinocytes after transfection with lipid/DNA complexes.
Histochemistry and cell biology.
2001 Jan; 115(1):41-7. doi:
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Biophysical journal.
2001 Jan; 80(1):313-23. doi:
10.1016/s0006-3495(01)76016-x. [PMID: 11159404] - D McKalip, M Grenier, M Choy. Liposomal mediated transfection of mature rat astrocytes in vitro: a comparison of ten reagents.
Neuroscience letters.
2000 Dec; 295(1-2):64-6. doi:
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