1,2-Dioleoyl-rac-glycerol (BioDeep_00000172373)

   

human metabolite blood metabolite natural product


代谢物信息卡片


1-hydroxy-3-(octadec-9-enoyloxy)propan-2-yl octadec-9-enoate

  化学式: C39H72O5 (620.5379)
中文名称:
  谱图信息: 最多检出来源 Bos taurus(not specific) 45.83%

分子结构信息

SMILES: CCCCCCCCC=CCCCCCCCC(=O)OCC(CO)OC(=O)CCCCCCCC=CCCCCCCCC
InChI: InChI=1S/C39H72O5/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-38(41)43-36-37(35-40)44-39(42)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h17-20,37,40H,3-16,21-36H2,1-2H3


描述信息

同义名列表

2 个代谢物同义名

1-hydroxy-3-(octadec-9-enoyloxy)propan-2-yl octadec-9-enoate; 1,2-DIOLEOYL-RAC-GLYCEROL



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

10 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Debby P Chang, Marija Jankunec, Justas Barauskas, Fredrik Tiberg, Tommy Nylander. Adsorption of lipid liquid crystalline nanoparticles: effects of particle composition, internal structure, and phase behavior. Langmuir : the ACS journal of surfaces and colloids. 2012 Jul; 28(29):10688-96. doi: 10.1021/la301579g. [PMID: 22725977]
  • Ni Zeng, Quanyin Hu, Zhongyang Liu, Xiaoling Gao, Rongkuan Hu, Qingxiang Song, Guangzhi Gu, Huimin Xia, Lei Yao, Zhiqing Pang, Xinguo Jiang, Jun Chen, Liang Fang. Preparation and characterization of paclitaxel-loaded DSPE-PEG-liquid crystalline nanoparticles (LCNPs) for improved bioavailability. International journal of pharmaceutics. 2012 Mar; 424(1-2):58-66. doi: 10.1016/j.ijpharm.2011.12.058. [PMID: 22240390]
  • Nagao Totani, Sayuri Tateishi, Tatsuya Takimoto, Risa Shinohara, Hideaki Sasaki. Ferulic acid esters and weight-loss promoting effects in rats. Journal of oleo science. 2012; 61(6):331-6. doi: 10.5650/jos.61.331. [PMID: 22687778]
  • Ni Zeng, Xiaoling Gao, Quanyin Hu, Qingxiang Song, Huimin Xia, Zhongyang Liu, Guangzhi Gu, Mengyin Jiang, Zhiqing Pang, Hongzhuan Chen, Jun Chen, Liang Fang. Lipid-based liquid crystalline nanoparticles as oral drug delivery vehicles for poorly water-soluble drugs: cellular interaction and in vivo absorption. International journal of nanomedicine. 2012; 7(?):3703-18. doi: 10.2147/ijn.s32599. [PMID: 22888230]
  • Masao Shimizu, Junya Moriwaki, Daisuke Shiiba, Hidenori Nohara, Naoto Kudo, Yoshihisa Katsuragi. Elimination of glycidyl palmitate in diolein by treatment with activated bleaching earth. Journal of oleo science. 2012; 61(1):23-8. doi: 10.5650/jos.61.23. [PMID: 22188803]
  • Nagao Totani, Sayuri Tateishi, Tatsuya Takimoto, Yukari Maeda, Hideaki Sasaki. Gallic acid glycerol ester promotes weight-loss in rats. Journal of oleo science. 2011; 60(9):457-62. doi: 10.5650/jos.60.457. [PMID: 21852744]
  • Elsa Youngsteadt, Patricia Guerra Bustios, Coby Schal. Divergent chemical cues elicit seed collecting by ants in an obligate multi-species mutualism in lowland Amazonia. PloS one. 2010 Dec; 5(12):e15822. doi: 10.1371/journal.pone.0015822. [PMID: 21209898]
  • Camilla Cervin, Martina Tinzl, Markus Johnsson, Per-Anders Abrahamsson, Fredrik Tiberg, Nishtman Dizeyi. Properties and effects of a novel liquid crystal nanoparticle formulation of docetaxel in a prostate cancer mouse model. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2010 Oct; 41(2):369-75. doi: 10.1016/j.ejps.2010.07.003. [PMID: 20633647]
  • Justas Barauskas, Camilla Cervin, Marija Jankunec, Marija Spandyreva, Kristina Ribokaite, Fredrik Tiberg, Markus Johnsson. Interactions of lipid-based liquid crystalline nanoparticles with model and cell membranes. International journal of pharmaceutics. 2010 May; 391(1-2):284-91. doi: 10.1016/j.ijpharm.2010.03.016. [PMID: 20214966]
  • Erik Rosenbaum, Staffan Tavelin, Lennart B-A Johansson. A characterisation study on the application of inverted lyotropic phases for subcutaneous drug release. International journal of pharmaceutics. 2010 Mar; 388(1-2):52-7. doi: 10.1016/j.ijpharm.2009.12.032. [PMID: 20026201]
  • Moh'd A Salameh, Juergen Wiegel. Synthesis of fatty acid esters and diacylglycerols at elevated temperatures by alkalithermophilic lipases from Thermosyntropha lipolytica. Journal of industrial microbiology & biotechnology. 2009 Oct; 36(10):1281-7. doi: 10.1007/s10295-009-0610-3. [PMID: 19593631]
  • Guillaume Tresset. The multiple faces of self-assembled lipidic systems. PMC biophysics. 2009 Apr; 2(1):3. doi: 10.1186/1757-5036-2-3. [PMID: 19374753]
  • Richard M Epand, Yulia V Shulga, Heath C Timmons, Alexandra L Perri, Jitendra D Belani, Kirishanth Perinpanathan, Laura Beth Johnson-McIntire, Sandra Bajjalieh, Armela O Dicu, Cynthia Elias, Scott D Rychnovsky, Matthew K Topham. Substrate chirality and specificity of diacylglycerol kinases and the multisubstrate lipid kinase. Biochemistry. 2007 Dec; 46(49):14225-31. doi: 10.1021/bi701584v. [PMID: 18004883]
  • S Imamura, J Kobayashi, S Sakasegawa, A Nohara, K Nakajima, M Kawashiri, A Inazu, M Yamagishi, J Koizumi, H Mabuchi. A novel method for measuring human hepatic lipase activity in postheparin plasma. Journal of lipid research. 2007 Feb; 48(2):453-7. doi: 10.1194/jlr.d600022-jlr200. [PMID: 17090661]
  • Justas Barauskas, Audrius Misiunas, Torsten Gunnarsson, Fredrik Tiberg, Markus Johnsson. 'Sponge' nanoparticle dispersions in aqueous mixtures of diglycerol monooleate, glycerol dioleate, and polysorbate 80. Langmuir : the ACS journal of surfaces and colloids. 2006 Jul; 22(14):6328-34. doi: 10.1021/la060295f. [PMID: 16800694]
  • Keshun Yu, Charles T McCracken, Runzhi Li, David F Hildebrand. Diacylglycerol acyltransferases from Vernonia and Stokesia prefer substrates with vernolic acid. Lipids. 2006 Jun; 41(6):557-66. doi: 10.1007/s11745-006-5005-x. [PMID: 16981434]
  • E L Vodovozova, D V Evdokimov, Iu G Molotkovskiĭ. [Synthesis of a lipid derivative of the antitumor agent methotrexate]. Bioorganicheskaia khimiia. 2004 Nov; 30(6):663-5. doi: 10.1023/b:rubi.0000049779.60159.c5. [PMID: 15586820]
  • Ping Gao, Martha J Witt, Roy J Haskell, Kathryn M Zamora, John R Shifflett. Application of a mixture experimental design in the optimization of a self-emulsifying formulation with a high drug load. Pharmaceutical development and technology. 2004 Aug; 9(3):301-9. doi: 10.1081/pdt-200031441. [PMID: 15458235]
  • E V Gorb, S N Gorb. [Myrmecochorous syndrome]. Zhurnal obshchei biologii. 2001 Nov; 62(6):496-511. doi: ". [PMID: 11871267]
  • D J Sanders, D Howes, L K Earl. The absorption, distribution and excretion of 1- and 2-. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2001 Jul; 39(7):709-16. doi: 10.1016/s0278-6915(01)00017-5. [PMID: 11397517]