1,2-Dimethoxyethane (BioDeep_00000172369)

   

human metabolite blood metabolite


代谢物信息卡片


1,2-Dimethoxyethane, conjugate monoacid

化学式: C4H10O2 (90.0681)
中文名称: 聚乙二醇二甲醚 (NHD), 乙二醇二甲醚, 1,2-二甲氧基乙烷
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: COCCOC
InChI: InChI=1S/C4H10O2/c1-5-3-4-6-2/h3-4H2,1-2H3

描述信息

同义名列表

19 个代谢物同义名

1,2-Dimethoxyethane, conjugate monoacid; Polyethylene glycol dimethyl ether; Ethylene glycol dimethyl ether; Ethylenglykoldimethylether; Ethylenglycoldimethylether; alpha,beta-Dimethoxyethane; a,b-Dimethoxyethane; 1,2-DIMETHOXYETHANE; Dimethyl cellosolve; Α,β-dimethoxyethane; 1,2-Dimethoxyethan; 2,5-Dioxahexane; Dimethoxyethane; CH3OCH2CH2OCH3; Monoglyme; Glyme; Egdme; DME; 1,2-Dimethoxyethane



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Janos Balogh, Antsar Rih Hlil, Ibrahim El-Zoghbi, Muhammad Ghufran Rafique, Dalila Chouikhi, Mohammed Al-Hashimi, Hassan S Bazzi. Phase-Separable Polyisobutylene Palladium-PEPPSI Precatalysts: Synthesis and Application in Buchwald-Hartwig Amination. Macromolecular rapid communications. 2017 Aug; 38(15):. doi: 10.1002/marc.201700214. [PMID: 28627077]
  • Hu Wang, Tin Oo Khor, Qian Yang, Ying Huang, Tien-Yuan Wu, Constance Lay-Lay Saw, Wen Lin, Ioannis P Androulakis, Ah-Ng Tony Kong. Pharmacokinetics and pharmacodynamics of phase II drug metabolizing/antioxidant enzymes gene response by anticancer agent sulforaphane in rat lymphocytes. Molecular pharmaceutics. 2012 Oct; 9(10):2819-27. doi: 10.1021/mp300130k. [PMID: 22931102]
  • Susruta Samanta, Samira Hezaveh, Giuseppe Milano, Danilo Roccatano. Diffusion of 1,2-dimethoxyethane and 1,2-dimethoxypropane through phosphatidycholine bilayers: a molecular dynamics study. The journal of physical chemistry. B. 2012 May; 116(17):5141-51. doi: 10.1021/jp211564x. [PMID: 22409229]
  • Masumi Kamiyama, Michelle K Garner, Kristina M Farragut, Hiroyuki Kobori. The establishment of a primary culture system of proximal tubule segments using specific markers from normal mouse kidneys. International journal of molecular sciences. 2012; 13(4):5098-111. doi: 10.3390/ijms13045098. [PMID: 22606032]
  • Sampathkumar Rangasamy, Paul G McGuire, Arup Das. Diabetic retinopathy and inflammation: novel therapeutic targets. Middle East African journal of ophthalmology. 2012 Jan; 19(1):52-9. doi: 10.4103/0974-9233.92116. [PMID: 22346115]
  • Qiong-Yi Zhao, Yi Wang, Yi-Meng Kong, Da Luo, Xuan Li, Pei Hao. Optimizing de novo transcriptome assembly from short-read RNA-Seq data: a comparative study. BMC bioinformatics. 2011 Dec; 12 Suppl 14(?):S2. doi: 10.1186/1471-2105-12-s14-s2. [PMID: 22373417]
  • Pedro Romero-Aroca, Marc Baget-Bernaldiz, Juan Fernandez-Ballart, Nuria Plana-Gil, Nuria Soler-Lluis, Isabel Mendez-Marin, Angel Bautista-Perez. Ten-year incidence of diabetic retinopathy and macular edema. Risk factors in a sample of people with type 1 diabetes. Diabetes research and clinical practice. 2011 Oct; 94(1):126-32. doi: 10.1016/j.diabres.2011.07.004. [PMID: 21802760]
  • Rehab Benarous, Muhammad B Sasongko, Salmaan Qureshi, Eva Fenwick, Mohamed Dirani, Tien Y Wong, Ecosse L Lamoureux. Differential association of serum lipids with diabetic retinopathy and diabetic macular edema. Investigative ophthalmology & visual science. 2011 Sep; 52(10):7464-9. doi: 10.1167/iovs.11-7598. [PMID: 21862642]
  • Allen Clermont, Tamie J Chilcote, Takeshi Kita, Jia Liu, Priscilla Riva, Sukanto Sinha, Edward P Feener. Plasma kallikrein mediates retinal vascular dysfunction and induces retinal thickening in diabetic rats. Diabetes. 2011 May; 60(5):1590-8. doi: 10.2337/db10-1260. [PMID: 21444925]
  • Jungdon Bae, Eun Hwa Choi, Jae-Gu Pan. Efficient synthesis of octyl-β-d-galactopyranoside by Bacillus spore-displayed β-galactosidase using an amphiphilic 1,2-dimethoxyethane co-solvent. Enzyme and microbial technology. 2011 Mar; 48(3):232-8. doi: 10.1016/j.enzmictec.2010.11.002. [PMID: 22112905]
  • Jean Claude Ansquer, Dominique Crimet, Christelle Foucher. Fibrates and statins in the treatment of diabetic retinopathy. Current pharmaceutical biotechnology. 2011 Mar; 12(3):396-405. doi: 10.2174/138920111794480570. [PMID: 20939802]
  • Jens Keilwagen, Jan Grau, Ivan A Paponov, Stefan Posch, Marc Strickert, Ivo Grosse. De-novo discovery of differentially abundant transcription factor binding sites including their positional preference. PLoS computational biology. 2011 Feb; 7(2):e1001070. doi: 10.1371/journal.pcbi.1001070. [PMID: 21347314]
  • Popchai Ngamskulrungroj, Jennifer Price, Tania Sorrell, John R Perfect, Wieland Meyer. Cryptococcus gattii virulence composite: candidate genes revealed by microarray analysis of high and less virulent Vancouver island outbreak strains. PloS one. 2011 Jan; 6(1):e16076. doi: 10.1371/journal.pone.0016076. [PMID: 21249145]
  • Maria de la Paz Celorio-Mancera, Juliette Courtiade, Alexander Muck, David G Heckel, Richard O Musser, Heiko Vogel. Sialome of a generalist lepidopteran herbivore: identification of transcripts and proteins from Helicoverpa armigera labial salivary glands. PloS one. 2011; 6(10):e26676. doi: 10.1371/journal.pone.0026676. [PMID: 22046331]
  • Jin-Xiu Xu, Mu Yang, Ke-Jun Deng, Hong Zhou. Antioxidant activities of Dracocephalum tanguticum maxim extract and its up-regulation on the expression of neurotrophic factors in a rat model of permanent focal cerebral ischemia. The American journal of Chinese medicine. 2011; 39(1):65-81. doi: 10.1142/s0192415x11008658. [PMID: 21213399]
  • Rebecca A Mosher, Ek Han Tan, Juhyun Shin, Robert L Fischer, Craig S Pikaard, David C Baulcombe. An atypical epigenetic mechanism affects uniparental expression of Pol IV-dependent siRNAs. PloS one. 2011; 6(10):e25756. doi: 10.1371/journal.pone.0025756. [PMID: 22003406]
  • Yonatan Serlin, Jaime Levy, Hadar Shalev. Vascular pathology and blood-brain barrier disruption in cognitive and psychiatric complications of type 2 diabetes mellitus. Cardiovascular psychiatry and neurology. 2011; 2011(?):609202. doi: 10.1155/2011/609202. [PMID: 21350721]
  • Burak Turgut, Fatih Cem Gul, Nevin Ilhan, Tamer Demir, Ulku Celiker. Comparison of serum glycosylated hemoglobin levels in patients with diabetic cystoid macular edema with and without serous macular detachment. Indian journal of ophthalmology. 2010 Sep; 58(5):381-4. doi: 10.4103/0301-4738.67044. [PMID: 20689191]
  • Daniela Ennulat, Dana Walker, Frances Clemo, Michal Magid-Slav, David Ledieu, Mark Graham, Suzanne Botts, Laura Boone. Effects of hepatic drug-metabolizing enzyme induction on clinical pathology parameters in animals and man. Toxicologic pathology. 2010 Aug; 38(5):810-28. doi: 10.1177/0192623310374332. [PMID: 20585144]
  • Augusto Simoes-Barbosa, Robert P Hirt, Patricia J Johnson. A metazoan/plant-like capping enzyme and cap modified nucleotides in the unicellular eukaryote Trichomonas vaginalis. PLoS pathogens. 2010 Jul; 6(7):e1000999. doi: 10.1371/journal.ppat.1000999. [PMID: 20664792]
  • Rosemary Castorina, Asa Bradman, Laura Fenster, Dana Boyd Barr, Roberto Bravo, Michelle G Vedar, Martha E Harnly, Thomas E McKone, Ellen A Eisen, Brenda Eskenazi. Comparison of current-use pesticide and other toxicant urinary metabolite levels among pregnant women in the CHAMACOS cohort and NHANES. Environmental health perspectives. 2010 Jun; 118(6):856-63. doi: 10.1289/ehp.0901568. [PMID: 20129873]
  • Alexandros B Tsoupras, Maria Roulia, Eleftherios Ferentinos, Ioannis Stamatopoulos, Constantinos A Demopoulos, Panayotis Kyritsis. Structurally diverse metal coordination compounds, bearing imidodiphosphinate and diphosphinoamine ligands, as potential inhibitors of the platelet activating factor. Bioinorganic chemistry and applications. 2010; ?(?):. doi: 10.1155/2010/731202. [PMID: 20689709]
  • Valerie A Smith, Terrell Johnson. Evaluation of an animal product-free variant of MegaCell MEM as a storage medium for corneas destined for transplantation. Ophthalmic research. 2010; 43(1):33-42. doi: 10.1159/000246576. [PMID: 19829010]
  • Jordi Muntané. Regulation of drug metabolism and transporters. Current drug metabolism. 2009 Oct; 10(8):932-45. doi: 10.2174/138920009790274595. [PMID: 20201827]
  • Banu Turgut Ozturk, Banu Bozkurt, Hurkan Kerimoglu, Mehmet Okka, Umit Kamis, Kemal Gunduz. Effect of serum cytokines and VEGF levels on diabetic retinopathy and macular thickness. Molecular vision. 2009 Sep; 15(?):1906-14. doi: NULL. [PMID: 19784389]
  • Matthias Bolz, Ursula Schmidt-Erfurth, Gabor Deak, Georgios Mylonas, Katharina Kriechbaum, Christoph Scholda. Optical coherence tomographic hyperreflective foci: a morphologic sign of lipid extravasation in diabetic macular edema. Ophthalmology. 2009 May; 116(5):914-20. doi: 10.1016/j.ophtha.2008.12.039. [PMID: 19410950]
  • David J Browning, Michael M Altaweel, Neil M Bressler, Susan B Bressler, Ingrid U Scott. Diabetic macular edema: what is focal and what is diffuse?. American journal of ophthalmology. 2008 Nov; 146(5):649-55, 655.e1. doi: 10.1016/j.ajo.2008.07.013. [PMID: 18774122]
  • Maria Gabriela Manuele, Graciela Ferraro, Claudia Anesini. Effect of Tilia x viridis flower extract on the proliferation of a lymphoma cell line and on normal murine lymphocytes: contribution of monoterpenes, especially limonene. Phytotherapy research : PTR. 2008 Nov; 22(11):1520-6. doi: 10.1002/ptr.2524. [PMID: 18688792]
  • David Gaucher, Clemence Sebah, Ali Erginay, Belkacem Haouchine, Ramin Tadayoni, Alain Gaudric, Pascale Massin. Optical coherence tomography features during the evolution of serous retinal detachment in patients with diabetic macular edema. American journal of ophthalmology. 2008 Feb; 145(2):289-296. doi: 10.1016/j.ajo.2007.09.029. [PMID: 18054885]
  • Harrihar A Pershadsingh, David M Moore. PPARgamma Agonists: Potential as Therapeutics for Neovascular Retinopathies. PPAR research. 2008; 2008(?):164273. doi: 10.1155/2008/164273. [PMID: 18509499]
  • Bruno A Furlani, Carsten H Meyer, Eduardo B Rodrigues, Mauricio Maia, Michel E Farah, Fernando M Penha, Frank G Holz. Emerging pharmacotherapies for diabetic macular edema. Expert opinion on emerging drugs. 2007 Nov; 12(4):591-603. doi: 10.1517/14728214.12.4.591. [PMID: 17979601]
  • M Vaughn Emerson, Andreas K Lauer. Emerging therapies for the treatment of neovascular age-related macular degeneration and diabetic macular edema. BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy. 2007; 21(4):245-57. doi: 10.2165/00063030-200721040-00005. [PMID: 17628122]
  • Noriko Hatano, Atsushi Mizota, Minoru Tanaka. Vitreous surgery for diabetic macular edema--its prognosis and correlation between preoperative systemic and ocular conditions and visual outcome. Annals of ophthalmology (Skokie, Ill.). 2007; 39(3):222-7. doi: 10.1007/s12009-007-0027-4. [PMID: 18025629]
  • M Rema, B K Srivastava, B Anitha, R Deepa, V Mohan. Association of serum lipids with diabetic retinopathy in urban South Indians--the Chennai Urban Rural Epidemiology Study (CURES) Eye Study--2. Diabetic medicine : a journal of the British Diabetic Association. 2006 Sep; 23(9):1029-36. doi: 10.1111/j.1464-5491.2006.01890.x. [PMID: 16922712]
  • Christine Vogel, Cyrus Chothia. Protein family expansions and biological complexity. PLoS computational biology. 2006 May; 2(5):e48. doi: 10.1371/journal.pcbi.0020048. [PMID: 16733546]
  • Kozo Yokota, Naoko Ikeda, Yasushi Johyama, Hiromi Michitsuji, Seiji Yamada. Urinary methoxyacetic acid as an indicator of occupational exposure to ethylene glycol dimethyl ether. International archives of occupational and environmental health. 2005 Sep; 78(8):650-4. doi: 10.1007/s00420-005-0014-2. [PMID: 16001212]
  • Zhi-min Yang, Xiang-jiang Tang, Ying-rong Lao. [Systematic evaluation on clinical literature related with treatment of Parkinson's disease with traditional Chinese medicine]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine. 2005 Jul; 25(7):612-5. doi: ". [PMID: 16089137]
  • Jian-xing Ma, Sarah X Zhang, Joshua J Wang. Down-regulation of angiogenic inhibitors: a potential pathogenic mechanism for diabetic complications. Current diabetes reviews. 2005 May; 1(2):183-96. doi: 10.2174/1573399054022839. [PMID: 18220594]
  • Hirotoshi Furukawa, Masanobu Takahashi, Koichiro Nakamura, Fumio Kaneko. Effect of an antiallergic drug (Olopatadine hydrochloride) on TARC/CCL17 and MDC/CCL22 production by PBMCs from patients with atopic dermatitis. Journal of dermatological science. 2004 Dec; 36(3):165-72. doi: 10.1016/j.jdermsci.2004.09.001. [PMID: 15541638]
  • Kristin A Waite, Dennis E Vance. Dimethylethanolamine does not prevent liver failure in phosphatidylethanolamine N-methyltransferase-deficient mice fed a choline-deficient diet. Biochimica et biophysica acta. 2004 Mar; 1636(2-3):175-82. doi: 10.1016/j.bbalip.2003.10.014. [PMID: 15164765]
  • Zoubida Karim, Amel Attmane-Elakeb, Valérie Sibella, Maurice Bichara. Acid pH increases the stability of BSC1/NKCC2 mRNA in the medullary thick ascending limb. Journal of the American Society of Nephrology : JASN. 2003 Sep; 14(9):2229-36. doi: 10.1097/01.asn.0000085023.73801.4a. [PMID: 12937298]
  • Hideharu Funatsu, Hidetoshi Yamashita, Tomohiro Ikeda, Tatsuya Mimura, Shuichiro Eguchi, Sadao Hori. Vitreous levels of interleukin-6 and vascular endothelial growth factor are related to diabetic macular edema. Ophthalmology. 2003 Sep; 110(9):1690-6. doi: 10.1016/s0161-6420(03)00568-2. [PMID: 13129863]
  • Hideharu Funatsu, Hidetoshi Yamashita, Tomohiro Ikeda, Tatsuya Mimura, Erika Shimizu, Sadao Hori. Relation of diabetic macular edema to cytokines and posterior vitreous detachment. American journal of ophthalmology. 2003 Mar; 135(3):321-7. doi: 10.1016/s0002-9394(02)01971-2. [PMID: 12614749]
  • Hideharu Funatsu, Hidetoshi Yamashita, Tomohiro Ikeda, Yuichiro Nakanishi, Shigehiko Kitano, Sadao Hori. Angiotensin II and vascular endothelial growth factor in the vitreous fluid of patients with diabetic macular edema and other retinal disorders. American journal of ophthalmology. 2002 Apr; 133(4):537-43. doi: 10.1016/s0002-9394(02)01323-5. [PMID: 11931788]
  • C N Backhouse, C L Delporte, R E Negrete, S Erazo, A Zuñiga, A Pinto, B K Cassels. Active constituents isolated from Psoralea glandulosa L. with antiinflammatory and antipyretic activities. Journal of ethnopharmacology. 2001 Nov; 78(1):27-31. doi: 10.1016/s0378-8741(01)00309-9. [PMID: 11585684]
  • M Rizk, F Belal, F Ibrahim, S Ahmed, N M el-Enany. Voltammetric determination of praziquantel in tablets and biological fluids. Arzneimittel-Forschung. 2001; 51(8):673-8. doi: 10.1055/s-0031-1300099. [PMID: 11556129]
  • L Almeida-Lopes, J Rigau, R A Zângaro, J Guidugli-Neto, M M Jaeger. Comparison of the low level laser therapy effects on cultured human gingival fibroblasts proliferation using different irradiance and same fluence. Lasers in surgery and medicine. 2001; 29(2):179-84. doi: 10.1002/lsm.1107. [PMID: 11553908]
  • M Sano. Subcellular localizations of guanylate cyclase and 3',5'-cyclic nucleotide phosphodiesterase in sea urchin sperm. Biochimica et biophysica acta. 1976 Apr; 428(2):525-31. doi: 10.1016/0304-4165(76)90061-1. [PMID: 6049]