1,2-Diethylbenzene (BioDeep_00000172361)
human metabolite blood metabolite natural product
代谢物信息卡片
化学式: C10H14 (134.1095)
中文名称: 1,2-二乙基苯, 1,2-二乙苯
谱图信息:
最多检出来源 Homo sapiens(blood) 100%
分子结构信息
SMILES: CCC1=CC=CC=C1CC
InChI: InChI=1S/C10H14/c1-3-9-7-5-6-8-10(9)4-2/h5-8H,3-4H2,1-2H3
数据库引用编号
6 个数据库交叉引用编号
- PubChem: 8657
- HMDB: HMDB0244072
- ChEMBL: CHEMBL3186870
- chemspider: 8335
- CAS: 135-01-3
- LOTUS: LTS0149334
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
10 个相关的物种来源信息
- 2759 - Eukaryota: LTS0149334
- 3633 - Gossypium: LTS0149334
- 3635 - Gossypium hirsutum: 10.1021/JF60200A011
- 3635 - Gossypium hirsutum: LTS0149334
- 9606 - Homo sapiens: -
- 3398 - Magnoliopsida: LTS0149334
- 3629 - Malvaceae: LTS0149334
- 35493 - Streptophyta: LTS0149334
- 58023 - Tracheophyta: LTS0149334
- 33090 - Viridiplantae: LTS0149334
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
亚细胞结构定位 | 关联基因列表 |
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文献列表
- Jean-Paul Payan, Stephane Binet, Dominique Beydon, Elisabeth Ferrari. Bio-distribution study of 1,2-diethylbenzene and its main metabolites by whole-body autoradiography and tissue homogenates.
Archives of toxicology.
2008 Sep; 82(9):591-600. doi:
10.1007/s00204-008-0281-2
. [PMID: 18253718] - Karla D Thrall, Richard A Gies, Allison M Cartmell, Hong Wu, Jolen J Soelberg, Joel A Klein. A liquid chromatographic-mass spectrometric method to evaluate the distribution kinetics of 1,2-diethylbenzene and its metabolite 1,2-diacetylbenzene in the F344 male rat.
Journal of toxicology and environmental health. Part A.
2007 Jan; 70(1):67-72. doi:
10.1080/15287390600751173
. [PMID: 17162499] - M S Kim, M I Sabri, V H Miller, R J Kayton, D A Dixon, P S Spencer. 1,2-diacetylbenzene, the neurotoxic metabolite of a chromogenic aromatic solvent, induces proximal axonopathy.
Toxicology and applied pharmacology.
2001 Dec; 177(2):121-31. doi:
10.1006/taap.2001.9301
. [PMID: 11740911] - J P Payan, B Cossec, D Beydon, J P Fabry, E Ferrari. Toxicokinetics and metabolism of 1,2-diethylbenzene in male Sprague Dawley rats--part 2: evidence for in vitro and in vivo stereoselectivity of 1,2-diethylbenzene metabolism.
Drug metabolism and disposition: the biological fate of chemicals.
2001 Jun; 29(6):868-76. doi:
NULL
. [PMID: 11353756] - J P Payan, D Beydon, B Cossec, A Ensminger, J P Fabry, E Ferrari. Toxicokinetics of 1,2-diethylbenzene in male Sprague-Dawley rats-part 1: excretion and metabolism of [(14)C]1,2-diethylbenzene.
Drug metabolism and disposition: the biological fate of chemicals.
1999 Dec; 27(12):1470-8. doi:
NULL
. [PMID: 10570029] - A M Saillenfait, J P Payan, I Langonné, F Gallissot, J P Sabaté, D Beydon, J P Fabry. Assessment of the developmental toxicity and placental transfer of 1,2-diethylbenzene in rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
1999 Nov; 37(11):1089-96. doi:
10.1016/s0278-6915(99)00105-2
. [PMID: 10566880] - I Linhart, Z Weidenhoffer, P Sedmera, M Polásekj, J Smejkal. Biotransformation of diethenylbenzenes, V. Identification of urinary metabolites of 1,2-diethenylbenzene in the rat.
Xenobiotica; the fate of foreign compounds in biological systems.
1996 Dec; 26(12):1263-72. doi:
10.3109/00498259609047230
. [PMID: 9004456] - F Gagnaire, A Ensminger, B Marignac, J De Ceaurriz. Possible involvement of 1,2-diacetylbenzene in diethylbenzene-induced neuropathy in rats.
Journal of applied toxicology : JAT.
1991 Aug; 11(4):261-8. doi:
10.1002/jat.2550110406
. [PMID: 1939999] - F Gagnaire, B Marignac, J de Ceaurriz. Diethylbenzene-induced sensorimotor neuropathy in rats.
Journal of applied toxicology : JAT.
1990 Apr; 10(2):105-12. doi:
10.1002/jat.2550100208
. [PMID: 2362075]