1,1,1,2,3,3-Hexafluoro-2-propanol (BioDeep_00000172330)

   

human metabolite blood metabolite


代谢物信息卡片


1,1,1,2,3,3-Hexafluoro-2-propanol

化学式: C3H2F6O (168.001)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(blood) 93.33%

分子结构信息

SMILES: C(C(C(F)(F)F)(O)F)(F)F
InChI: InChI=1S/C3H2F6O/c4-1(5)2(6,10)3(7,8)9/h1,10H

描述信息

D001697 - Biomedical and Dental Materials

同义名列表

3 个代谢物同义名

1,1,1,2,3,3-Hexafluoro-2-propanol; 1,1,1,2,3,3-hexafluoropropan-2-ol; Hexafluoro-2-propanol



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Evelyne Furger, Sergey N Fedosov, Dorte Launholt Lildballe, Robert Waibel, Roger Schibli, Ebba Nexo, Eliane Fischer. Comparison of recombinant human haptocorrin expressed in human embryonic kidney cells and native haptocorrin. PloS one. 2012; 7(5):e37421. doi: 10.1371/journal.pone.0037421. [PMID: 22662153]
  • Andrea C Klaver, Mary P Coffey, Lynnae M Smith, David A Bennett, John M Finke, Loan Dang, David A Loeffler. ELISA measurement of specific non-antigen-bound antibodies to Aβ1-42 monomer and soluble oligomers in sera from Alzheimer's disease, mild cognitively impaired, and noncognitively impaired subjects. Journal of neuroinflammation. 2011 Aug; 8(?):93. doi: 10.1186/1742-2094-8-93. [PMID: 21827691]
  • Francesca Intranuovo, Pietro Favia, Eloisa Sardella, Chiara Ingrosso, Marina Nardulli, Riccardo d'Agostino, Roberto Gristina. Osteoblast-like cell behavior on plasma deposited micro/nanopatterned coatings. Biomacromolecules. 2011 Feb; 12(2):380-7. doi: 10.1021/bm101136n. [PMID: 21190339]
  • Muzaddid Sarker, Jarratt Rose, Mark McDonald, Michael R Morrow, Valerie Booth. Modifications to surfactant protein B structure and lipid interactions under respiratory distress conditions: consequences of tryptophan oxidation. Biochemistry. 2011 Jan; 50(1):25-36. doi: 10.1021/bi101426s. [PMID: 21128671]
  • Ewa D Micewicz, Amy L Cole, Chun-Ling Jung, Hai Luong, Martin L Phillips, Pratikhya Pratikhya, Shantanu Sharma, Alan J Waring, Alexander M Cole, Piotr Ruchala. Grifonin-1: a small HIV-1 entry inhibitor derived from the algal lectin, Griffithsin. PloS one. 2010 Dec; 5(12):e14360. doi: 10.1371/journal.pone.0014360. [PMID: 21179548]
  • Haruhiko Yagi, Heinrich Frank, Albrecht Seidel, Donald M Jerina. Revised assignment of absolute configuration of the cis- and trans-N6-deoxyadenosine adducts at C14 of (+/-)-11beta,12alpha-dihydroxy-13alpha,14alpha-epoxy-11,12,13,14-tetrahydrodibenzo[a,l]pyrene by stereoselective synthesis. Chemical research in toxicology. 2008 Dec; 21(12):2379-92. doi: 10.1021/tx800268f. [PMID: 19053320]
  • Haruhiko Yagi, Donald M Jerina. Fluorinated alcohol mediated displacement of the C10 acetoxy group of benzo[a]pyrene-7,8,9,10-tetrahydrotetraol tetraacetates: a new route to diol epoxide-deoxyguanosine adducts. The Journal of organic chemistry. 2007 Dec; 72(26):9983-90. doi: 10.1021/jo701705c. [PMID: 18047370]
  • Rakez Kayed, Elizabeth Head, Floyd Sarsoza, Tommy Saing, Carl W Cotman, Mihaela Necula, Lawrence Margol, Jessica Wu, Leonid Breydo, Jennifer L Thompson, Suhail Rasool, Tatyana Gurlo, Peter Butler, Charles G Glabe. Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers. Molecular neurodegeneration. 2007 Sep; 2(?):18. doi: 10.1186/1750-1326-2-18. [PMID: 17897471]
  • Haruhiko Yagi, Donald M Jerina. Fluorinated alcohol mediated control over cis vs trans opening of benzo[a]pyrene-7,8-diol 9,10-epoxides at C-10 by the exocyclic amino groups of O6-allyl protected deoxyguanosine and of deoxyadenosine. The Journal of organic chemistry. 2007 Aug; 72(16):6037-45. doi: 10.1021/jo070303c. [PMID: 17608435]
  • Haruhiko Yagi, Heinrich Frank, Albrecht Seidel, Donald M Jerina. Synthesis and absolute configuration of cis- and trans-opened cyclopenta[cd]pyrene 3,4-oxide N2-deoxyguanosine adducts: conversion to phosphoramidites for oligonucleotide synthesis. Chemical research in toxicology. 2007 Apr; 20(4):650-61. doi: 10.1021/tx600286z. [PMID: 17355153]
  • Guowei Dai, Xiaohui Wei, Zhongfa Liu, Shujun Liu, Guido Marcucci, Kenneth K Chan. Characterization and quantification of Bcl-2 antisense G3139 and metabolites in plasma and urine by ion-pair reversed phase HPLC coupled with electrospray ion-trap mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2005 Oct; 825(2):201-13. doi: 10.1016/j.jchromb.2005.05.049. [PMID: 16111926]
  • J F Bian, W R Lujan, D Harper-Nixon, H S Jeon, D H Weinkauf. Effect of hexafluoropropylene oxide plasma polymer particle coatings on the rheological properties of boron nitride/poly(dimethylsiloxane) composites. Journal of colloid and interface science. 2005 Oct; 290(2):582-91. doi: 10.1016/j.jcis.2005.04.075. [PMID: 15925377]
  • Antonio Accorsi, Barbara Morrone, Irene Domenichini, Simona Valenti, Giovanni Battista Raffi, Francesco Saverio Violante. Urinary sevoflurane and hexafluoro-isopropanol as biomarkers of low-level occupational exposure to sevoflurane. International archives of occupational and environmental health. 2005 Jun; 78(5):369-78. doi: 10.1007/s00420-004-0580-8. [PMID: 15864632]
  • Valerie Booth, Alan J Waring, Frans J Walther, Kevin M W Keough. NMR structures of the C-terminal segment of surfactant protein B in detergent micelles and hexafluoro-2-propanol. Biochemistry. 2004 Dec; 43(48):15187-94. doi: 10.1021/bi0481895. [PMID: 15568810]
  • Larissa A Munishkina, Cassandra Phelan, Vladimir N Uversky, Anthony L Fink. Conformational behavior and aggregation of alpha-synuclein in organic solvents: modeling the effects of membranes. Biochemistry. 2003 Mar; 42(9):2720-30. doi: 10.1021/bi027166s. [PMID: 12614167]
  • Haruhiko Yagi, Andagar R Ramesha, Govind Kalena, Jane M Sayer, Subodh Kumar, Donald M Jerina. Novel stereoselective control over cis vs trans opening of benzo[c]phenanthrene 3,4-diol 1,2-epoxides by the exocyclic N(2)-amino group of deoxyguanosine in the presence of hexafluoropropan-2-ol. The Journal of organic chemistry. 2002 Sep; 67(19):6678-89. doi: 10.1021/jo020418a. [PMID: 12227797]