1,1-Difluoroethane (BioDeep_00000172318)

   

human metabolite blood metabolite Volatile Flavor Compounds


代谢物信息卡片


Ethylidene difluoride

化学式: C2H4F2 (66.0281048)
中文名称: 1,1-二氟乙烷
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(F)F
InChI: InChI=1S/C2H4F2/c1-2(3)4/h2H,1H3

描述信息

同义名列表

5 个代谢物同义名

Ethylidene difluoride; 11-Difluoro-ethane; 1,1-Difluoroethane; Difluoroethane; 1,1-Difluoroethane



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Nilton Salles Rosa Neto, Daniel Englert, William H McAlister, Steven Mumm, David Mills, Deborah J Veis, Alan Burshell, Alan Boyde, Michael P Whyte. Periarticular calcifications containing giant pseudo-crystals of francolite in skeletal fluorosis from 1,1-difluoroethane "huffing". Bone. 2022 07; 160(?):116421. doi: 10.1016/j.bone.2022.116421. [PMID: 35429657]
  • Nicholas B Tiscione, Timothy P Rohrig. 1,1-Difluoroethane Forensic Aspects for the Toxicologist and Pathologist. Journal of analytical toxicology. 2021 Sep; 45(8):792-798. doi: 10.1093/jat/bkab054. [PMID: 34017986]
  • Kaushal Joshi, Michael Barletta, John Wurpel. Cardiotoxic (Arrhythmogenic) Effects of 1,1-Difluoroethane Due to Electrolyte Imbalance and Cardiomyocyte Damage. The American journal of forensic medicine and pathology. 2017 Jun; 38(2):115-125. doi: 10.1097/paf.0000000000000262. [PMID: 28263233]
  • Joseph R Tucci, Gary M Whitford, William H McAlister, Deborah V Novack, Steven Mumm, Tony M Keaveny, Michael P Whyte. Skeletal Fluorosis Due To Inhalation Abuse of a Difluoroethane-Containing Computer Cleaner. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2017 01; 32(1):188-195. doi: 10.1002/jbmr.2923. [PMID: 27449958]
  • Suwen Kumar, Tejaswini Joginpally, David Kim, Mrinal Yadava, Konchok Norgais, Heather S Laird-Fick. Cardiomyopathy from 1,1-Difluoroethane Inhalation. Cardiovascular toxicology. 2016 Oct; 16(4):370-3. doi: 10.1007/s12012-015-9348-5. [PMID: 26613951]
  • Lena Ernstgård, Bengt Sjögren, Sara Gunnare, Gunnar Johanson. Blood and exhaled air can be used for biomonitoring of hydrofluorocarbon exposure. Toxicology letters. 2014 Feb; 225(1):102-9. doi: 10.1016/j.toxlet.2013.11.026. [PMID: 24296009]
  • Lena Ernstgård, Bengt Sjögren, Wolfgang Dekant, Tobias Schmidt, Gunnar Johanson. Uptake and disposition of 1,1-difluoroethane (HFC-152a) in humans. Toxicology letters. 2012 Feb; 209(1):21-9. doi: 10.1016/j.toxlet.2011.11.028. [PMID: 22155657]
  • Nicholas B Tiscione, Ilene Alford, Dustin Tate Yeatman, Xiaoqin Shan. Ethanol analysis by headspace gas chromatography with simultaneous flame-ionization and mass spectrometry detection. Journal of analytical toxicology. 2011 Sep; 35(7):501-11. doi: 10.1093/anatox/35.7.501. [PMID: 21871160]
  • Kentaro Sakai, Kyoko Maruyama-Maebashi, Akihiro Takatsu, Kenji Fukui, Tomonori Nagai, Miwako Aoyagi, Eriko Ochiai, Kimiharu Iwadate. Sudden death involving inhalation of 1,1-difluoroethane (HFC-152a) with spray cleaner: three case reports. Forensic science international. 2011 Mar; 206(1-3):e58-61. doi: 10.1016/j.forsciint.2010.08.026. [PMID: 20875935]
  • Joseph Avella, Naveen Kunaparaju, Sunil Kumar, Michael Lehrer, S William Zito, Michael Barletta. Uptake and distribution of the abused inhalant 1,1-difluoroethane in the rat. Journal of analytical toxicology. 2010 Sep; 34(7):381-8. doi: 10.1093/jat/34.7.381. [PMID: 20822675]
  • Lena Ernstgård, Birger Lind, Melvin E Andersen, Gunnar Johanson. Liquid-air partition coefficients of 1,1-difluoroethane (HFC152a), 1,1,1-trifluoroethane (HFC143a), 1,1,1,2-tetrafluoroethane (HFC134a), 1,1,1,2,2-pentafluoroethane (HFC125) and 1,1,1,3,3-pentafluoropropane (HFC245fa). Journal of applied toxicology : JAT. 2010 Jan; 30(1):59-62. doi: 10.1002/jat.1473. [PMID: 19701883]
  • Joseph Avella, Michael Lehrer, S William Zito. A validated method for the quantitation of 1,1-difluoroethane using a gas in equilibrium method of calibration. Journal of analytical toxicology. 2008 Oct; 32(8):680-7. doi: 10.1093/jat/32.8.680. [PMID: 19007521]
  • Timothy Hahn, Joseph Avella, Michael Lehrer. A motor vehicle accident fatality involving the inhalation of 1,1-difluoroethane. Journal of analytical toxicology. 2006 Oct; 30(8):638-42. doi: 10.1093/jat/30.8.638. [PMID: 17132266]
  • G D Prestwich, Y Xu, L Qian, J Gajewiak, G Jiang. New metabolically stabilized analogues of lysophosphatidic acid: agonists, antagonists and enzyme inhibitors. Biochemical Society transactions. 2005 Dec; 33(Pt 6):1357-61. doi: 10.1042/bst0331357. [PMID: 16246118]
  • Ester Marotta, Cristina Paradisi, Gianfranco Scorrano. An atmospheric pressure chemical ionization study of the positive and negative ion chemistry of the hydrofluorocarbons 1,1-difluoroethane (HFC-152a) and 1,1,1,2-tetrafluoroethane (HFC-134a) and of perfluoro-n-hexane (FC-72) in air plasma at atmospheric pressure. Journal of mass spectrometry : JMS. 2004 Jul; 39(7):791-801. doi: 10.1002/jms.653. [PMID: 15282758]