1-Benzylisoquinoline (BioDeep_00000172161)

   

human metabolite blood metabolite


代谢物信息卡片


Bis-benzyl-isoquinolines

化学式: C16H13N (219.1048)
中文名称: 1-苄基异喹啉
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(C1=CC=CC=C1)C1=NC=CC2=CC=CC=C12
InChI: InChI=1S/C16H13N/c1-2-6-13(7-3-1)12-16-15-9-5-4-8-14(15)10-11-17-16/h1-11H,12H2



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Minghui Feng, Yuwen Chen, Jingzhi Chen, Wei Guo, Pei Zhao, Chen Zhang, Xiaoli Shan, Huihua Chen, Ming Xu, Rong Lu. Stachydrine hydrochloride protects the ischemic heart by ameliorating endoplasmic reticulum stress through a SERCA2a dependent way and maintaining intracellular Ca2+ homeostasis. European journal of pharmacology. 2024 Jun; 973(?):176585. doi: 10.1016/j.ejphar.2024.176585. [PMID: 38636799]
  • Jiawen Song, Yushi Liu, Yurou Guo, Minghao Yuan, Wenxiao Zhong, Jiamei Tang, Yiping Guo, Li Guo. Therapeutic effects of tetrandrine in inflammatory diseases: a comprehensive review. Inflammopharmacology. 2024 Jun; 32(3):1743-1757. doi: 10.1007/s10787-024-01452-9. [PMID: 38568399]
  • Wencheng Xu, Shuhe Chen, Xiaoqin Wang, Jinwen Min, Sachiko Tanaka, Kenji Onda, Kentaro Sugiyama, Haruki Yamada, Toshihiko Hirano. Cepharanthine synergistically promotes methylprednisolone pharmacodynamics against human peripheral blood mononuclear cells possibly via regulation of P-glycoprotein/glucocorticoid receptor translocation. BMC complementary medicine and therapies. 2024 May; 24(1):186. doi: 10.1186/s12906-024-04489-z. [PMID: 38734604]
  • Zhoujie An, Ranran Gao, Shanshan Chen, Ya Tian, Qi Li, Lixia Tian, Wanran Zhang, Lingzhe Kong, Baojiang Zheng, Lijun Hao, Tianyi Xin, Hui Yao, Yu Wang, Wei Song, Xin Hua, Chengwei Liu, Jingyuan Song, Huahao Fan, Wei Sun, Shilin Chen, Zhichao Xu. Lineage-Specific CYP80 Expansion and Benzylisoquinoline Alkaloid Diversity in Early-Diverging Eudicots. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2024 May; 11(19):e2309990. doi: 10.1002/advs.202309990. [PMID: 38477432]
  • Peiliang Zhang, Jiadong Li, Jiyao Shi, Zhihong Cheng, Tao Wu. Structurally Diverse Bisbenzylisoquinoline Alkaloids with Antiadipogenic Activity through PPARγ Downregulation from the Embryo of Nelumbo nucifera Seeds. Journal of natural products. 2024 Apr; 87(4):1013-1022. doi: 10.1021/acs.jnatprod.3c01290. [PMID: 38483204]
  • Jiangping Yang, Liujie Qin, Shouchang Zhou, Jixing Li, Yu Tu, Minfeng Mo, Xuenian Liu, Jinglun Huang, Xiumei Qin, Aijun Jiao, Wei Wei, Peilin Yang. Network pharmacology, molecular docking and experimental study of CEP in nasopharyngeal carcinoma. Journal of ethnopharmacology. 2024 Apr; 323(?):117667. doi: 10.1016/j.jep.2023.117667. [PMID: 38159821]
  • Zhuo Liu, Shaoqin Shen, Yujie Wang, Shuqi Sun, Tong Yu, Yanhong Fu, Rong Zhou, Chunjin Li, Rui Cao, Yanshu Zhang, Nan Li, Liangdan Sun, Xiaoming Song. The genome of Stephania japonica provides insights into the biosynthesis of cepharanthine. Cell reports. 2024 Mar; 43(3):113832. doi: 10.1016/j.celrep.2024.113832. [PMID: 38381605]
  • Yunfang Yang, Changjiang Li, Sijin Yang, Zhuo Zhang, Xue Bai, Hongmei Tang, Jiang Huang. Cepharanthine maintains integrity of the blood-brain barrier (BBB) in stroke via the VEGF/VEGFR2/ZO-1 signaling pathway. Aging. 2024 Mar; 16(7):5905-5915. doi: 10.18632/aging.205678. [PMID: 38517394]
  • Iman Khaldari, Mohammad Reza Naghavi, Elaheh Motamedi, Meisam Zargar. The effects of green and chemically-synthesized copper oxide nanoparticles on the production and gene expression of morphinan alkaloids in Oriental poppy. Scientific reports. 2024 03; 14(1):6000. doi: 10.1038/s41598-024-56709-8. [PMID: 38472367]
  • Xiuyu Liu, Ying Ma, Junling Bu, Conglong Lian, Rui Ma, Qishuang Li, Xiang Jiao, Zhimin Hu, Yun Chen, Suiqing Chen, Juan Guo, Luqi Huang. Characterization of CYP82 genes involved in the biosynthesis of structurally diverse benzylisoquinoline alkaloids in Corydalis yanhusuo. Plant molecular biology. 2024 Mar; 114(2):23. doi: 10.1007/s11103-023-01397-7. [PMID: 38453737]
  • Gan-Qing Xia, Mei-Peng Zhu, Jian-Wen Li, Hui Huang. An alkaloid from Menispermum dauricum, dauricine mediates Ca2+ influx and inhibits NF-κB pathway to protect chondrocytes from IL-1β-induced inflammation and catabolism. Journal of ethnopharmacology. 2024 Mar; 321(?):117560. doi: 10.1016/j.jep.2023.117560. [PMID: 38081396]
  • Seungki Lee, Nam-Il Park, Yeri Park, Kyong-Cheul Park, Eun Sil Kim, Youn Kyoung Son, Beom-Soon Choi, Nam-Soo Kim, Ik-Young Choi. O- and N-Methyltransferases in benzylisoquinoline alkaloid producing plants. Genes & genomics. 2024 Mar; 46(3):367-378. doi: 10.1007/s13258-023-01477-4. [PMID: 38095842]
  • Li Fang, Rong Shen, Yao Lu, Xiangfeng Xu, Fang Huang. Tetrandrine alleviates inflammation and promotes macrophage M2 polarization in gouty arthritis by NF-κB-mediated Lcp1. Cellular and molecular biology (Noisy-le-Grand, France). 2024 Feb; 70(2):205-211. doi: 10.14715/cmb/2024.70.2.29. [PMID: 38430024]
  • Liang Leng, Zhichao Xu, Bixia Hong, Binbin Zhao, Ya Tian, Can Wang, Lulu Yang, Zhongmei Zou, Lingyu Li, Ke Liu, Wanjun Peng, Jiangning Liu, Zhoujie An, Yalin Wang, Baozhong Duan, Zhigang Hu, Chuan Zheng, Sanyin Zhang, Xiaodong Li, Maochen Li, Zhaoyu Liu, Zenghao Bi, Tianxing He, Baimei Liu, Huahao Fan, Chi Song, Yigang Tong, Shilin Chen. Cepharanthine analogs mining and genomes of Stephania accelerate anti-coronavirus drug discovery. Nature communications. 2024 Feb; 15(1):1537. doi: 10.1038/s41467-024-45690-5. [PMID: 38378731]
  • Jie Ling, Xiao Li, Maolin Wang, Chaozheng Zhang, Yilan Liu, Xin Zhang, Changqun Liu, Qing Ren, Yingjie Zeng, Chuanqi Wang, Ying Chen, Chen Sun, Hongyu Chen, Yi Zuo, Xiujun Cao, Yun Deng, Bo Ren, Defang Li, Jun Lu. Novel sulfonyl-substituted tetrandrine derivatives for colon cancer treatment by inducing mitochondrial apoptosis and inhibiting PI3K/AKT/mTOR pathway. Bioorganic chemistry. 2024 Feb; 143(?):107069. doi: 10.1016/j.bioorg.2023.107069. [PMID: 38160477]
  • Huang Hongmei, Yang Maojun, L I Ting, Wang Dandan, L I Ying, Tang Xiaochi, Yuan Lu, G U Shi, X U Yong. Neferine inhibits the progression of diabetic nephropathy by modulating the miR-17-5p/nuclear factor E2-related factor 2 axis. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan. 2024 Feb; 44(1):44-53. doi: 10.19852/j.cnki.jtcm.20231204.004. [PMID: 38213238]
  • Yang Liu, Jia-Yu Cai, Yang Liu, Lu Zhang, Rui-Bo Guo, Xue-Tao Li, Ling-Yue Ma, Liang Kong. Borneol-modified docetaxel plus tetrandrine micelles for treatment of drug-resistant brain glioma. Drug development and industrial pharmacy. 2024 Jan; ?(?):1-15. doi: 10.1080/03639045.2024.2302886. [PMID: 38235554]
  • Alfonso Reyes-Luna, Eunice Yáñez-Barrientos, Xochitl N Alba-Mares, José Luis Olivares-Romero, Ángel Josabad Alonso-Castro, David Cruz Cruz, Clarisa Villegas Gómez. Metabolomic Approaches in Assessing the Insecticidal Activity of the Extracts from Argemone ochroleuca Sweet (Papaveraceae) Against Three Diverse Crop Pests of Economic Importance. Chemistry & biodiversity. 2024 Jan; ?(?):e202301279. doi: 10.1002/cbdv.202301279. [PMID: 38190837]
  • Na Kou, Yi-Bing Chen, Xian-Wen Li, Dong Xu, Yue Wang, Xin-Ran Dong, Yuan-Lu Cui, Qiangsong Wang. Pulmonary administration of tetrandrine loaded Zinc-Alginate nanogels attenuates pulmonary fibrosis in rats. International journal of pharmaceutics. 2024 Jan; 649(?):123625. doi: 10.1016/j.ijpharm.2023.123625. [PMID: 37984618]
  • Yunyan Chen, Ziwei Zhang, Zhilei Qian, Rui Ma, Minna Luan, Yu Sun. Sequentially Released Liposomes Enhance Anti-Liver Cancer Efficacy of Tetrandrine and Celastrol-Loaded Coix Seed Oil. International journal of nanomedicine. 2024; 19(?):727-742. doi: 10.2147/ijn.s446895. [PMID: 38288265]
  • Xiao Zhao, Yuan Pan, Jun Tan, Hui Lv, Yu Wang, Da-Xia Chen. Metabolomics and transcriptomics reveal the mechanism of alkaloid synthesis in Corydalis yanhusuo bulbs. PloS one. 2024; 19(5):e0304258. doi: 10.1371/journal.pone.0304258. [PMID: 38781178]
  • Ze-Dong Nan, Yi-Dong Zhu, Chao-Fan Deng, Guo-Dong Jiang, Zhen-Zhen Wang, Chong-Long Li, Xiao-Li Ma, Zhi-Bo Jiang. Benzylisoquinoline alkaloids with their antitumor activity from the aerial parts of Corydalis impatiens (pall.) Fisch. Fitoterapia. 2024 Jan; 172(?):105738. doi: 10.1016/j.fitote.2023.105738. [PMID: 37939736]
  • Zhengyu Fang, Peihong Lin, Rui Gao, Wenjing Yang, Aizhen Zhou, Wenying Yu. Preparation, Characterization, and Anti-Lung Cancer Activity of Tetrandrine-Loaded Stealth Liposomes. International journal of nanomedicine. 2024; 19(?):787-803. doi: 10.2147/ijn.s431599. [PMID: 38293606]
  • Wangming Zhang, Xiaojing Yu, Linchun Bao, Tianhui He, Weidong Pan, Pinhao Li, Jinhe Liu, Xiaohua Liu, Liuqi Yang, Jielin Liu. Bisbenzylisoquinoline alkaloid fangchinoline derivative HY-2 inhibits breast cancer cells by suppressing BLM DNA helicase. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023 Dec; 169(?):115908. doi: 10.1016/j.biopha.2023.115908. [PMID: 37988849]
  • Yichao Liang, Jun Li, Honglin Xu, Mingjie Pang, Changlei Hu, Xie Weng, Wei Xie. Cepharanthine suppresses proliferation and metastasis and enhances apoptosis by regulating JAK2/Stat3 pathway in hepatocellular carcinoma. Cellular and molecular biology (Noisy-le-Grand, France). 2023 Dec; 69(14):94-100. doi: 10.14715/cmb/2023.69.14.15. [PMID: 38279472]
  • Min Zhang, Ziming Wang, Kailin Li, Qing Li, Kaiquan Yu, Jiaxin Li, Jinglin Feng, Biao Yang, Lianghong Liu, Wei Cai. The visualization of the spatial distribution of Cocculus orbiculatus based on air flow-assisted desorption electrospray ionization mass spectrometry imaging. Fitoterapia. 2023 Dec; 173(?):105785. doi: 10.1016/j.fitote.2023.105785. [PMID: 38122856]
  • Meirong Gao, Yuxin Zhao, Zhanyi Yao, Qianhe Su, Payton Van Beek, Zengyi Shao. Xylose and shikimate transporters facilitates microbial consortium as a chassis for benzylisoquinoline alkaloid production. Nature communications. 2023 Nov; 14(1):7797. doi: 10.1038/s41467-023-43049-w. [PMID: 38016984]
  • Kaitao Wang, Jiapeng Deng, Jialong Yang, An Wang, Minle Ye, Qingyu Chen, Guodong Chen, Dingsheng Lin. Tetrandrine promotes the survival of the random skin flap via the PI3K/AKT signaling pathway. Phytotherapy research : PTR. 2023 Nov; ?(?):. doi: 10.1002/ptr.8058. [PMID: 37909161]
  • Hui Jiang, Chunming Tang, Yuanyuan Wen, Qianqian Zhao, Mingyuan Xu, Jinting Fan, Zhiji Wang, Lifeng Wang, Huae Xu, Gang Chen. Enhanced Antitumor Efficacy of Novel Biomimetic Platelet Membrane-Coated Tetrandrine Nanoparticles in Nonsmall Cell Lung Cancer. Molecular pharmaceutics. 2023 Oct; ?(?):. doi: 10.1021/acs.molpharmaceut.3c00310. [PMID: 37823637]
  • Marutpong Detarya, Panupong Mahalapbutr, Orawan Waenphimai, Sonexai Kidoikhammouan, Somkid Janeklang, Kanlayanee Sawanyawisuth, Kulthida Vaeteewoottacharn, Wunchana Seubwai, Charupong Saengboonmee, Teerawut Thothaisong, Wachirachai Pabuprapap, Apichart Suksamrarn, Sopit Wongkham. Induction of apoptotic cell death of cholangiocarcinoma cells by tiliacorinine from Tiliacora triandra: A mechanistic insight. Biochimica et biophysica acta. General subjects. 2023 Oct; 1867(12):130486. doi: 10.1016/j.bbagen.2023.130486. [PMID: 37813201]
  • Jia-Shu Chen, Xu Guo, Jin-Yue Sun, Mu-Xuan Wang, Xiu-Zheng Gao, Zhen Wang, Jin-Long Han, Hui Sun, Kai Zhang, Chao Liu. Fangchinoline derivatives inhibits PI3K signaling in vitro and in vivo in non-small cell lung cancer. Bioorganic chemistry. 2023 09; 138(?):106623. doi: 10.1016/j.bioorg.2023.106623. [PMID: 37295240]
  • Kun Jiang, Xiao Liu, Yu-Ming Liu, Li-Ning Wang, Ya-Ting Xiao, Feng-Chen Wu. Bioactive Isoquinoline Alkaloids with Diverse Skeletons from Fissistigma polyanthum. Journal of natural products. 2023 Aug; ?(?):. doi: 10.1021/acs.jnatprod.3c00391. [PMID: 37615114]
  • Min Wang, Kai Liu, Zhongming Zhou, Huizhuan Geng. miR-638 suppresses cervical cancer progression by inhibiting NCAPG2 under the treatment of Tetrandrine. Histology and histopathology. 2023 Aug; ?(?):18657. doi: 10.14670/hh-18-657. [PMID: 37702425]
  • YingZheng Wang, Tong Wang, HuaXin Wang, WeiDong Liu, Xiao Li, XiaoYan Wang, YaNan Zhang. A mechanistic updated overview on Cepharanthine as potential anticancer agent. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023 Jul; 165(?):115107. doi: 10.1016/j.biopha.2023.115107. [PMID: 37423171]
  • Ke Liu, Bixia Hong, Shuqi Wang, Fuxing Lou, Yecheng You, Ruolan Hu, Amna Shafqat, Huahao Fan, Yigang Tong. Pharmacological Activity of Cepharanthine. Molecules (Basel, Switzerland). 2023 Jun; 28(13):. doi: 10.3390/molecules28135019. [PMID: 37446681]
  • Muhammad Hafiz Husna Hasnan, Yasodha Sivasothy, Kooi Yeong Khaw, Mohd Azlan Nafiah, Hazrina Hazni, Marc Litaudon, Wan Adriyani Wan Ruzali, Sook Yee Liew, Khalijah Awang. N-Methyl Costaricine and Costaricine, Two Potent Butyrylcholinesterase Inhibitors from Alseodaphne pendulifolia Gamb. International journal of molecular sciences. 2023 Jun; 24(13):. doi: 10.3390/ijms241310699. [PMID: 37445877]
  • Wei Liu, Xufang Tian, Ying Feng, Juan Hu, Bo Wang, Shilin Chen, Di Liu, Yifei Liu. Genome-wide analysis of bHLH gene family in Coptis chinensis provides insights into the regulatory role in benzylisoquinoline alkaloid biosynthesis. Plant physiology and biochemistry : PPB. 2023 Jun; 201(?):107846. doi: 10.1016/j.plaphy.2023.107846. [PMID: 37390693]
  • Liangliang Shi, Shuaizhe Wang, Shangzu Zhang, Jiawei Wang, Yaping Chen, Yangyang Li, Zhiwei Liu, Sichen Zhao, Benjun Wei, Liying Zhang. Research progress on pharmacological effects and mechanisms of cepharanthine and its derivatives. Naunyn-Schmiedeberg's archives of pharmacology. 2023 Jun; ?(?):. doi: 10.1007/s00210-023-02537-y. [PMID: 37338575]
  • Ming-Yue Wang, Shao-Shi Zhang, Meng-Fei An, Yue-Fei Xia, Mao-Si Fan, Ze-Rui Sun, Li-Juan Zhang, Yun-Li Zhao, Jun Sheng, Xuan-Jun Wang. Neferine ameliorates nonalcoholic steatohepatitis through regulating AMPK pathway. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2023 Jun; 114(?):154798. doi: 10.1016/j.phymed.2023.154798. [PMID: 37031639]
  • Agrataben Vadhel, Sabreen Bashir, Ashiq Hussain Mir, Madhuri Girdhar, Deepak Kumar, Anil Kumar, Aradhana Mohan, Tabarak Malik, Anand Mohan. Opium alkaloids, biosynthesis, pharmacology and association with cancer occurrence. Open biology. 2023 May; 13(5):220355. doi: 10.1098/rsob.220355. [PMID: 37132222]
  • Aswad Khadilkar, Zoie L Bunch, Jessica Wagoner, Vandana Ravindran, Jessica M Oda, Warren S Vidar, Trevor N Clark, Preston K Manwill, Daniel A Todd, Sarah A Barr, Lauren K Olinger, Susan L Fink, Wendy K Strangman, Roger G Linington, John B MacMillan, Nadja B Cech, Stephen J Polyak. Modulation of in Vitro SARS-CoV-2 Infection by Stephania tetrandra and Its Alkaloid Constituents. Journal of natural products. 2023 Apr; 86(4):1061-1073. doi: 10.1021/acs.jnatprod.3c00159. [PMID: 37043739]
  • Ling-Yan Wang, Gui-Yang Xia, Huan Xia, Xiao-Hong Wei, Sheng Lin. (±)-Yanhusuomide A, a pair of ornithine-fused benzylisoquinoline enantiomers from Corydalis yanhusuo. Bioorganic chemistry. 2023 04; 133(?):106407. doi: 10.1016/j.bioorg.2023.106407. [PMID: 36758275]
  • Michael E Pyne, Nicholas D Gold, Vincent J J Martin. Pathway elucidation and microbial synthesis of proaporphine and bis-benzylisoquinoline alkaloids from sacred lotus (Nelumbo nucifera). Metabolic engineering. 2023 Mar; ?(?):. doi: 10.1016/j.ymben.2023.03.010. [PMID: 37004909]
  • Lu Liu, Dan Liang, Qiao Zheng, Maoyuan Zhao, RuiTing Lv, Jianyuan Tang, Nianzhi Chen. Berbamine dihydrochloride suppresses the progression of colorectal cancer via RTKs/Akt axis. Journal of ethnopharmacology. 2023 Mar; 303(?):116025. doi: 10.1016/j.jep.2022.116025. [PMID: 36496042]
  • Ivette M Menéndez-Perdomo, Peter J Facchini. Elucidation of the (R)-enantiospecific benzylisoquinoline alkaloid biosynthetic pathways in sacred lotus (Nelumbo nucifera). Scientific reports. 2023 Feb; 13(1):2955. doi: 10.1038/s41598-023-29415-0. [PMID: 36805479]
  • Patil Shivprasad Suresh, Veerbhan Kesarwani, Surekha Kumari, Ravi Shankar, Upendra Sharma. Bisbenzylisoquinolines from Cissampelos pareira L. as antimalarial agents: Molecular docking, pharmacokinetics analysis, and molecular dynamic simulation studies. Computational biology and chemistry. 2023 Feb; 104(?):107826. doi: 10.1016/j.compbiolchem.2023.107826. [PMID: 36848855]
  • Nopawit Khamto, Kraikrit Utama, Suriya Tateing, Padchanee Sangthong, Puracheth Rithchumpon, Nathaporn Cheechana, Aroonchai Saiai, Natthawat Semakul, Winita Punyodom, Puttinan Meepowpan. Discovery of Natural Bisbenzylisoquinoline Analogs from the Library of Thai Traditional Plants as SARS-CoV-2 3CLPro Inhibitors: In Silico Molecular Docking, Molecular Dynamics, and In Vitro Enzymatic Activity. Journal of chemical information and modeling. 2023 Jan; ?(?):. doi: 10.1021/acs.jcim.2c01309. [PMID: 36647612]
  • Jiaqi Chen, Tianfu Jiang, Jiajun Jiang, Linfang Deng, Yiting Liu, Zhuoheng Zhong, Hongwei Fu, Bingxian Yang, Lin Zhang. The chloroplast GATA-motif of Mahonia bealei participates in alkaloid-mediated photosystem inhibition during dark to light transition. Journal of plant physiology. 2023 Jan; 280(?):153894. doi: 10.1016/j.jplph.2022.153894. [PMID: 36525836]
  • Qiong Jin, Xu-Jie Qin, Zhi Dai, Yun Zhao, Yan-Yan Zhu, Shan-Shan Chen, Ya-Ping Liu, Xiao-Dong Luo. Dimeric benzylisoquinoline alkaloids from Thalictrum delavayi and their biological activities. Fitoterapia. 2023 Jan; 164(?):105356. doi: 10.1016/j.fitote.2022.105356. [PMID: 36403942]
  • Li-Jun Yang, Zhong-Duo Yang, Zhi-Jie Li, Shu-Hong Yang, Zong-Mei Shu. Stephtetrandrine A-D, bisbenzylisoquinoline alkaloids from Stephania tetrandra. Natural product research. 2023 Jan; 37(2):204-215. doi: 10.1080/14786419.2021.1961135. [PMID: 34348525]
  • Chiufai Kuok, Qi Wang, Pedro Fong, Yong Qin, Lirong Meng. Inhibitory Effect of Hernandezine on the Proliferation of Hepatocellular Carcinoma. Biological & pharmaceutical bulletin. 2023; 46(2):245-256. doi: 10.1248/bpb.b22-00612. [PMID: 36724952]
  • Junhai Zhu, Lihong Huang, Fei Gao, Weijun Jian, Huahan Chen, Ming Liao, Wenbao Qi. Berbamine Hydrochloride Inhibits African Swine Fever Virus Infection In Vitro. Molecules (Basel, Switzerland). 2022 Dec; 28(1):. doi: 10.3390/molecules28010170. [PMID: 36615369]
  • Di Liang, Qi Li, Lina Du, Guifang Dou. Pharmacological Effects and Clinical Prospects of Cepharanthine. Molecules (Basel, Switzerland). 2022 Dec; 27(24):. doi: 10.3390/molecules27248933. [PMID: 36558061]
  • Da-Cheng Hao, Li-Jia Xu, Yu-Wei Zheng, Huai-Yu Lyu, Pei-Gen Xiao. Mining Therapeutic Efficacy from Treasure Chest of Biodiversity and Chemodiversity: Pharmacophylogeny of Ranunculales Medicinal Plants. Chinese journal of integrative medicine. 2022 Dec; 28(12):1111-1126. doi: 10.1007/s11655-022-3576-x. [PMID: 35809180]
  • Salma El-Sayed Radwan, Riham M El-Moslemany, Radwa A Mehanna, Eman H Thabet, Elsayeda-Zeinab A Abdelfattah, Amal El-Kamel. Chitosan-coated bovine serum albumin nanoparticles for topical tetrandrine delivery in glaucoma: in vitro and in vivo assessment. Drug delivery. 2022 Dec; 29(1):1150-1163. doi: 10.1080/10717544.2022.2058648. [PMID: 35384774]
  • Yipu Fan, Yihan Zhang, Kunyu Shi, Shan Cheng, Duanqing Pei, Xiaodong Shu. Identification of a group of bisbenzylisoquinoline (BBIQ) compounds as ferroptosis inhibitors. Cell death & disease. 2022 11; 13(11):1000. doi: 10.1038/s41419-022-05447-8. [PMID: 36435804]
  • Natali Ozber, Samuel C Carr, Jeremy S Morris, Siyu Liang, Jacinta L Watkins, Kristian M Caldo, Jillian M Hagel, Kenneth K S Ng, Peter J Facchini. Alkaloid binding to opium poppy major latex proteins triggers structural modification and functional aggregation. Nature communications. 2022 11; 13(1):6768. doi: 10.1038/s41467-022-34313-6. [PMID: 36351903]
  • Chang-Feng Song, Yu-Heng Hu, Zhi-Guo Mang, Zeng Ye, Hai-di Chen, De-Sheng Jing, Gui-Xiong Fan, Shun-Rong Ji, Xian-Jun Yu, Xiao-Wu Xu, Yi Qin. Hernandezine induces autophagic cell death in human pancreatic cancer cells via activation of the ROS/AMPK signaling pathway. Acta pharmacologica Sinica. 2022 Oct; ?(?):. doi: 10.1038/s41401-022-01006-1. [PMID: 36284209]
  • Jing Bai, Shuai Zhang, Jinjing Cao, Hongbin Sun, Zhiguo Mang, Wei L Shen, Hao Li. Hernandezine, a natural herbal alkaloid, ameliorates type 2 diabetes by activating AMPK in two mouse models. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2022 Oct; 105(?):154366. doi: 10.1016/j.phymed.2022.154366. [PMID: 35933900]
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