1-Aminobenzotriazole (BioDeep_00000172145)

   

human metabolite blood metabolite Volatile Flavor Compounds


代谢物信息卡片


1H-1,2,3-benzotriazol-1-amine

化学式: C6H6N4 (134.0592436)
中文名称: 1-氨基苯并三唑
谱图信息: 最多检出来源 Homo sapiens(blood) 97.5%

分子结构信息

SMILES: C1=CC=C2C(=C1)N=NN2N
InChI: InChI=1S/C6H6N4/c7-10-6-4-2-1-3-5(6)8-9-10/h1-4H,7H2



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Santosh Kumar Pandey, Harish Nakka, Sudhakar R Ambhore, Shalini Londhe, Vinod Kumar Goyal, Ramakrishna Nirogi. Short-term toxicity study of 1-aminobenzotraizole, a CYP inhibitor, in Wistar rats. Drug and chemical toxicology. 2022 Jul; 45(4):1597-1605. doi: 10.1080/01480545.2020.1850755. [PMID: 33249936]
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  • Qin Yue, Teresa Mulder, Patrick J Rudewicz, Eric Solon, Nageshwar Budha, Joseph A Ware, Joseph Lyssikatos, Cornelis E C A Hop, Harvey Wong, S Cyrus Khojasteh. Evaluation of metabolism and disposition of GDC-0152 in rats using 14C labeling strategy at two different positions: a novel formation of hippuric acid from 4-phenyl-5-amino-1,2,3-thiadiazole. Drug metabolism and disposition: the biological fate of chemicals. 2013 Feb; 41(2):508-17. doi: 10.1124/dmd.112.047019. [PMID: 23223496]
  • Herve Aloysius, Vincent W Tong, Jocelyn Yabut, Scott A Bradley, Jackie Shang, Yan Zou, Richard A Tschirret-Guth. Metabolic activation and major protein target of a 1-benzyl-3-carboxyazetidine sphingosine-1-phosphate-1 receptor agonist. Chemical research in toxicology. 2012 Jul; 25(7):1412-22. doi: 10.1021/tx300017s. [PMID: 22765480]
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  • Ai-fang Li, Guo-lin Shen, Shi-yong Jiao, Hua Li, Qi Wang. [Metabolic detoxification of bakuchiol is mediated by cytochrome P450 enzymes in human liver microsomes]. Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences. 2012 Jun; 44(3):431-6. doi: NULL. [PMID: 22692316]
  • Robert L Walsky, Jonathan N Bauman, Karine Bourcier, Georgina Giddens, Kimberly Lapham, Andre Negahban, Tim F Ryder, R Scott Obach, Ruth Hyland, Theunis C Goosen. Optimized assays for human UDP-glucuronosyltransferase (UGT) activities: altered alamethicin concentration and utility to screen for UGT inhibitors. Drug metabolism and disposition: the biological fate of chemicals. 2012 May; 40(5):1051-65. doi: 10.1124/dmd.111.043117. [PMID: 22357286]
  • Jonas Aper, Els Mechant, Baruch Rubin, Arne Heyerick, Gert Callebaut, Sven Mangelinckx, Dieter Deforce, Norbert De Kimpe, Robert Bulcke, Dirk Reheul. Absorption, translocation and metabolism of metamitron in Chenopodium album. Pest management science. 2012 Feb; 68(2):209-16. doi: 10.1002/ps.2246. [PMID: 21800410]
  • Q Sun, T W Harper, E A Dierks, L Zhang, S Chang, A D Rodrigues, P Marathe. 1-Aminobenzotriazole, a known cytochrome P450 inhibitor, is a substrate and inhibitor of N-acetyltransferase. Drug metabolism and disposition: the biological fate of chemicals. 2011 Sep; 39(9):1674-9. doi: 10.1124/dmd.111.039834. [PMID: 21677062]
  • Licy L Yanes, Roberta Lima, Mohadetheh Moulana, Damian G Romero, Kuichang Yuan, Michael J Ryan, Rodney Baker, Huimin Zhang, Fan Fan, Deborah D Davis, Richard J Roman, Jane F Reckelhoff. Postmenopausal hypertension: role of 20-HETE. American journal of physiology. Regulatory, integrative and comparative physiology. 2011 Jun; 300(6):R1543-8. doi: 10.1152/ajpregu.00387.2010. [PMID: 21474427]
  • M Kuczeriszka, K H Olszyński, A Gąsiorowska, J Sadowski, E Kompanowska-Jezierska. Interaction of nitric oxide and the cytochrome P-450 system on blood pressure and renal function in the rat: dependence on sodium intake. Acta physiologica (Oxford, England). 2011 Apr; 201(4):493-502. doi: 10.1111/j.1748-1716.2010.02222.x. [PMID: 21073660]
  • Shinji Shimizu, Ryo Atsumi, Tsunenori Nakazawa, Takashi Izumi, Kenichi Sudo, Osamu Okazaki, Hideo Saji. Ticlopidine-induced hepatotoxicity in a GSH-depleted rat model. Archives of toxicology. 2011 Apr; 85(4):347-53. doi: 10.1007/s00204-010-0594-9. [PMID: 20871981]
  • Yongchuan Gu, Christopher P Guise, Kashyap Patel, Maria R Abbattista, Jie Li, Jie Lie, Xueying Sun, Graham J Atwell, Maruta Boyd, Adam V Patterson, William R Wilson. Reductive metabolism of the dinitrobenzamide mustard anticancer prodrug PR-104 in mice. Cancer chemotherapy and pharmacology. 2011 Mar; 67(3):543-55. doi: 10.1007/s00280-010-1354-5. [PMID: 20473609]
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  • Jean Aghofack-Nguemezi, Christopher Fuchs, Su-Ying Yeh, Fong-Chin Huang, Thomas Hoffmann, Wilfried Schwab. An oxygenase inhibitor study in Solanum lycopersicum combined with metabolite profiling analysis revealed a potent peroxygenase inactivator. Journal of experimental botany. 2011 Jan; 62(3):1313-23. doi: 10.1093/jxb/erq368. [PMID: 21115664]
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  • Hagai Yasuor, Wei Zou, Vladimir V Tolstikov, Ronald S Tjeerdema, Albert J Fischer. Differential oxidative metabolism and 5-ketoclomazone accumulation are involved in Echinochloa phyllopogon resistance to clomazone. Plant physiology. 2010 May; 153(1):319-26. doi: 10.1104/pp.110.153296. [PMID: 20207709]
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