1-(Perfluorohexyl)octane (BioDeep_00000172131)
human metabolite blood metabolite
代谢物信息卡片
化学式: C14H17F13 (432.11225979999995)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCCCCC(C(C(C(C(C(F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F
InChI: InChI=1S/C14H17F13/c1-2-3-4-5-6-7-8-9(15,16)10(17,18)11(19,20)12(21,22)13(23,24)14(25,26)27/h2-8H2,1H3
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相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
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1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Amy Zhuang-Yan, Yahiya Y Syed. Perfluorohexyloctane Ophthalmic Solution: A Review in Dry Eye Disease.
Drugs.
2024 Apr; 84(4):441-448. doi:
10.1007/s40265-024-02016-5. [PMID: 38554243] - Amr Saad, Andreas Frings. Influence of perfluorohexyloctane (Evotears®) on higher order aberrations.
International ophthalmology.
2023 Dec; 43(12):5025-5030. doi:
10.1007/s10792-023-02905-w. [PMID: 37864619] - John D Sheppard, David G Evans, Eugene E Protzko. A review of the first anti-evaporative prescription treatment for dry eye disease: perfluorohexyloctane ophthalmic solution.
The American journal of managed care.
2023 11; 29(14 Suppl):S251-S259. doi:
10.37765/ajmc.2023.89464. [PMID: 37930231] - Paul M Karpecki, Kelly K Nichols, John D Sheppard. Addressing excessive evaporation: an unmet need in dry eye disease.
The American journal of managed care.
2023 10; 29(13 Suppl):S239-S247. doi:
10.37765/ajmc.2023.89448. [PMID: 37844320] - Antonio Ballesteros-Sánchez, Concepción De-Hita-Cantalejo, María Carmen Sánchez-González, Zane Jansone-Langine, Maria Alvarez de Sotomayor, Josip Culig, José-María Sánchez-González. Perfluorohexyloctane in dry eye disease: A systematic review of its efficacy and safety as a novel therapeutic agent.
The ocular surface.
2023 Oct; 30(?):254-262. doi:
10.1016/j.jtos.2023.10.001. [PMID: 37813152] - Kirsten Julia Habbe, Andreas Frings, Amr Saad, Gerd Geerling. The influence of a mineral oil cationic nanoemulsion or perfluorohexyloctane on the tear film lipid layer and higher order aberrations.
PloS one.
2023; 18(1):e0279977. doi:
10.1371/journal.pone.0279977. [PMID: 36652431] - Doreen Schmidl, Ahmed M Bata, Stephan Szegedi, Valentin Aranha Dos Santos, Hannes Stegmann, Klemens Fondi, Sonja Krösser, René M Werkmeister, Leopold Schmetterer, Gerhard Garhöfer. Influence of Perfluorohexyloctane Eye Drops on Tear Film Thickness in Patients with Mild to Moderate Dry Eye Disease: A Randomized Controlled Clinical Trial.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics.
2020 04; 36(3):154-161. doi:
10.1089/jop.2019.0092. [PMID: 31895638] - Anna Chachaj-Brekiesz, Anita Wnętrzak, Ewelina Lipiec, Jan Kobierski, Patrycja Dynarowicz-Latka. Perfluorohexyloctane (F6H8) as a delivery agent for cyclosporine A in dry eye syndrome therapy - Langmuir monolayer study complemented with infrared nanospectroscopy.
Colloids and surfaces. B, Biointerfaces.
2019 Dec; 184(?):110564. doi:
10.1016/j.colsurfb.2019.110564. [PMID: 31704647] - Charalambos Tsagogiorgas, Friedrich Anger, Grietje Beck, Annette Breedijk, Benito Yard, Simone Hoeger. Impact of different emulsifiers on biocompatibility and inflammatory potential of Perfluorohexyloctane (F6H8) emulsions for new intravenous drug delivery systems.
Drug design, development and therapy.
2019; 13(?):2097-2110. doi:
10.2147/dddt.s195954. [PMID: 31417241] - C Tsagogiorgas, T Jung, J Krebs, B Theisinger, G Beck, B A Yard, M Quintel. Aerosolized semifluorinated alkanes as excipients are suitable for inhalative drug delivery--a pilot study.
International journal of pharmaceutics.
2012 Jan; 422(1-2):194-201. doi:
10.1016/j.ijpharm.2011.10.051. [PMID: 22079720] - René Holm, Erling Bonne Jørgensen, Michael Harborg, Rune Larsen, Per Holm, Anette Müllertz, Jette Jacobsen. A novel excipient, 1-perfluorohexyloctane shows limited utility for the oral delivery of poorly water-soluble drugs.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2011 Mar; 42(4):416-22. doi:
10.1016/j.ejps.2011.01.007. [PMID: 21256961] - Norbert Kociok, Claudia Gavranic, Bernd Kirchhof, Antonia M Joussen. Influence on membrane-mediated cell activation by vesicles of silicone oil or perfluorohexyloctane.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie.
2005 Apr; 243(4):345-58. doi:
10.1007/s00417-004-1039-z. [PMID: 15864624] - X Ding, C Li, L Lu, G Feng, H Zheng. Experiment study of effect of perfluorohexyloctane on corneal endothelial cells.
Yan ke xue bao = Eye science.
2001 Mar; 17(1):21-6. doi:
NULL. [PMID: 12567590]