1-(Naphthalen-2-yl)-2-(pyrrolidin-1-yl)pentan-1-one (BioDeep_00000172130)

   

human metabolite blood metabolite


代谢物信息卡片


1-(Naphthalen-2-yl)-2-(pyrrolidin-1-yl)pentan-1-one

化学式: C19H23NO (281.1779548)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCC(C(=O)C1=CC2=CC=CC=C2C=C1)N3CCCC3
InChI: InChI=1S/C19H23NO/c1-2-7-18(20-12-5-6-13-20)19(21)17-11-10-15-8-3-4-9-16(15)14-17/h3-4,8-11,14,18H,2,5-7,12-13H2,1H3

描述信息

同义名列表

7 个代谢物同义名

1-(Naphthalen-2-yl)-2-(pyrrolidin-1-yl)pentan-1-one; 1-Naphthalen-2-yl-2-pyrrolidin-1-ylpentan-1-one; NRG-1 (Naphyrone) CPD; Energy 1 (naphyrone); Naphthylpyrovalerone; NP-Pentanone; naphyrone



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Nikola Pinterova-Leca, Rachel R Horsley, Hynek Danda, Monika Žídková, Eva Lhotková, Klára Šíchová, Kristýna Štefková, Marie Balíková, Martin Kuchař, Tomáš Páleníček. Naphyrone (naphthylpyrovalerone): Pharmacokinetics, behavioural effects and thermoregulation in Wistar rats. Addiction biology. 2021 03; 26(2):e12906. doi: 10.1111/adb.12906. [PMID: 32378298]
  • Michelle Williams, Jennifer Martin, Peter Galettis. A Validated Method for the Detection of 32 Bath Salts in Oral Fluid. Journal of analytical toxicology. 2017 Oct; 41(8):659-669. doi: 10.1093/jat/bkx055. [PMID: 28985394]
  • Amy J Eshleman, Katherine M Wolfrum, Meagan G Hatfield, Robert A Johnson, Kevin V Murphy, Aaron Janowsky. Substituted methcathinones differ in transporter and receptor interactions. Biochemical pharmacology. 2013 Jun; 85(12):1803-15. doi: 10.1016/j.bcp.2013.04.004. [PMID: 23583454]
  • Lucas A Johnson, Rebecca L Johnson, Ray-Bernard Portier. Current 'legal highs'. The Journal of emergency medicine. 2013 Jun; 44(6):1108-15. doi: 10.1016/j.jemermed.2012.09.147. [PMID: 23528960]
  • Markus R Meyer, Denise Prosser, Hans H Maurer. Studies on the metabolism and detectability of the designer drug β-naphyrone in rat urine using GC-MS and LC-HR-MS/MS. Drug testing and analysis. 2013 Apr; 5(4):259-65. doi: 10.1002/dta.1443. [PMID: 23303532]
  • Adrian Derungs, Simeon Schietzel, Markus R Meyer, Hans H Maurer, Stephan Krähenbühl, Matthias E Liechti. Sympathomimetic toxicity in a case of analytically confirmed recreational use of naphyrone (naphthylpyrovalerone). Clinical toxicology (Philadelphia, Pa.). 2011 Aug; 49(7):691-3. doi: 10.3109/15563650.2011.592838. [PMID: 21740148]
  • David M Wood, Susannah Davies, Aaron Cummins, Jennifer Button, David W Holt, John Ramsey, Paul I Dargan. Energy-1 ('NRG-1'): don't believe what the newspapers say about it being legal. BMJ case reports. 2011 Feb; 2011(?):. doi: 10.1136/bcr.07.2010.3184. [PMID: 22714604]
  • Peter C Meltzer, David Butler, Jeffrey R Deschamps, Bertha K Madras. 1-(4-Methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one (Pyrovalerone) analogues: a promising class of monoamine uptake inhibitors. Journal of medicinal chemistry. 2006 Feb; 49(4):1420-32. doi: 10.1021/jm050797a. [PMID: 16480278]