2,5-Bis(3,4,5-trimethoxyphenyl)tetrahydrofuran (BioDeep_00000171995)
human metabolite blood metabolite
代谢物信息卡片
2,5-Bis(3,4,5-trimethoxyphenyl)tetrahydrofuran
化学式: C22H28O7 (404.1835)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: COC1=CC(=CC(=C1OC)OC)C2CCC(O2)C3=CC(=C(C(=C3)OC)OC)OC
InChI: InChI=1S/C22H28O7/c1-23-17-9-13(10-18(24-2)21(17)27-5)15-7-8-16(29-15)14-11-19(25-3)22(28-6)20(12-14)26-4/h9-12,15-16H,7-8H2,1-6H3
描述信息
同义名列表
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
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Plant Reactome(0)
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1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- M Watanabe, Y Arakida, J Tanabe, A Sugidachi, N Hirasawa, S Mue, K Ohuchi. Pharmacological analysis of neutrophil chemotactic factor production by leucocytes and roles of PAF in allergic inflammation in rats.
British journal of pharmacology.
1994 Jan; 111(1):123-30. doi:
10.1111/j.1476-5381.1994.tb14033.x. [PMID: 8012688] - Z N Chen. [Recent progress in the study of anti-PAF (platelet activating factor) constituents of medicinal herbs].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
1993 Jun; 18(6):323-6, 361, 380. doi:
". [PMID: 8274205] - J P Seale, S Nourshargh, P G Hellewell, T J Williams. Mechanism of action of platelet activating factor in the pulmonary circulation: an investigation using a novel isotopic system in rabbit isolated lung.
British journal of pharmacology.
1991 Sep; 104(1):251-7. doi:
10.1111/j.1476-5381.1991.tb12415.x. [PMID: 1786514] - N Perico, A Remuzzi, J Dadan, C Battaglia, G Remuzzi. Platelet-activating factor alters glomerular barrier size selectivity for macromolecules in rats.
The American journal of physiology.
1991 Jul; 261(1 Pt 2):F85-90. doi:
10.1152/ajprenal.1991.261.1.f85. [PMID: 1713421] - S B Hwang. High affinity receptor binding of platelet-activating factor in rat peritoneal polymorphonuclear leukocytes.
European journal of pharmacology.
1991 Apr; 196(2):169-75. doi:
10.1016/0014-2999(91)90424-o. [PMID: 1651872] - K J Bloch, B P Ng, S M Bishara, M Bloch. Inhibition of immune complex-induced enteropathy by three different platelet-activating factor receptor antagonists.
Prostaglandins.
1991 Mar; 41(3):237-49. doi:
10.1016/0090-6980(91)90044-g. [PMID: 1649481] - F Squadrito, R Sturniolo, D Altavilla, G Santoro, G M Campo, A Arena, A P Caputi. Platelet activating factor involvement in splanchnic artery occlusion shock in rats.
European journal of pharmacology.
1991 Jan; 192(1):47-53. doi:
10.1016/0014-2999(91)90067-z. [PMID: 2040364] - J S Warren, P A Barton, D M Mandel, K Matrosic. Intrapulmonary tumor necrosis factor triggers local platelet-activating factor production in rat immune complex alveolitis.
Laboratory investigation; a journal of technical methods and pathology.
1990 Dec; 63(6):746-54. doi:
NULL. [PMID: 2255183] - D G Moon, H van der Zee, K D Morton, J A Krasodomski, J E Kaplan, J W Fenton. Platelet activating factor and sheep platelets: a sensitive new bioassay.
Thrombosis research.
1990 Feb; 57(4):551-64. doi:
10.1016/0049-3848(90)90072-k. [PMID: 2326773] - M Watanabe, A Sugidachi, M Omata, N Hirasawa, S Mue, S Tsurufuji, K Ohuchi. Possible role for platelet-activating factor in neutrophil infiltration in allergic inflammation in rats.
International archives of allergy and applied immunology.
1990; 92(4):396-403. doi:
10.1159/000235171. [PMID: 2083975] - J S Warren, K J Johnson, P A Ward. PAF and immune complex-induced injury.
Journal of lipid mediators.
1990; 2 Suppl(?):S229-37. doi:
NULL. [PMID: 1966816] - F Guarner, J L Wallace, W K MacNaughton, G C Ibbotson, V Arroyo, J Rodés. Endotoxin-induced ascites formation in the rat: partial mediation by platelet-activating factor.
Hepatology (Baltimore, Md.).
1989 Nov; 10(5):788-94. doi:
10.1002/hep.1840100507. [PMID: 2807157] - D Macconi, A Benigni, M Morigi, A Ubiali, S Orisio, M Livio, N Perico, T Bertani, G Remuzzi, C Patrono. Enhanced glomerular thromboxane A2 mediates some pathophysiologic effect of platelet-activating factor in rabbit nephrotoxic nephritis: evidence from biochemical measurements and inhibitor trials.
The Journal of laboratory and clinical medicine.
1989 May; 113(5):549-60. doi:
. [PMID: 2541212] - M A Selak, J B Smith. Platelet-activating factor-induced calcium mobilization in human platelets and neutrophils: effects of PAF-acether antagonists.
Journal of lipid mediators.
1989 Mar; 1(2):125-37. doi:
. [PMID: 2519888] - G Danko, J E Sherwood, B Grissom, W Kreutner, R W Chapman. Effect of the PAF antagonists, CV-3988 and L-652,731 on the pulmonary and hematological responses to guinea pig anaphylaxis.
Pharmacological research communications.
1988 Sep; 20(9):785-98. doi:
10.1016/s0031-6989(88)80717-3. [PMID: 3174804] - M Livio, G Vigano, M Morigi, A Ubiali, M Galbusera, G Remuzzi. Role of platelet-activating factor in primary hemostasis.
The American journal of physiology.
1988 Jun; 254(6 Pt 2):H1218-23. doi:
10.1152/ajpheart.1988.254.6.h1218. [PMID: 2837916] - G M Vercellotti, H Q Yin, K S Gustafson, R D Nelson, H S Jacob. Platelet-activating factor primes neutrophil responses to agonists: role in promoting neutrophil-mediated endothelial damage.
Blood.
1988 Apr; 71(4):1100-7. doi:
". [PMID: 2451547] - N Perico, F Delaini, M Tagliaferri, M Abbate, M Cucchi, T Bertani, G Remuzzi. Effect of platelet-activating factor and its specific receptor antagonist on glomerular permeability to proteins in isolated perfused rat kidney.
Laboratory investigation; a journal of technical methods and pathology.
1988 Feb; 58(2):163-71. doi:
NULL. [PMID: 3123798] - J Wang, M J Dunn. Platelet-activating factor mediates endotoxin-induced acute renal insufficiency in rats.
The American journal of physiology.
1987 Dec; 253(6 Pt 2):F1283-9. doi:
10.1152/ajprenal.1987.253.6.f1283. [PMID: 2827506] - C Robaut, G Durand, C James, D Lave, P Sedivy, A Floch, S Mondot, D Pacot, I Cavero, G Le Fur. PAF binding sites. Characterization by [3H]52770 RP, a pyrrolo[1,2-c]thiazole derivative, in rabbit platelets.
Biochemical pharmacology.
1987 Oct; 36(19):3221-9. doi:
10.1016/0006-2952(87)90637-x. [PMID: 2822048] - B W Smallbone, N E Taylor, J W McDonald. Effects of L-652,731, a platelet-activating factor (PAF) receptor antagonist, on PAF- and complement-induced pulmonary hypertension in sheep.
The Journal of pharmacology and experimental therapeutics.
1987 Sep; 242(3):1035-40. doi:
NULL. [PMID: 2821222] - T Bertani, M Livio, D Macconi, M Morigi, G Bisogno, C Patrono, G Remuzzi. Platelet activating factor (PAF) as a mediator of injury in nephrotoxic nephritis.
Kidney international.
1987 Jun; 31(6):1248-56. doi:
10.1038/ki.1987.138. [PMID: 3039232] - P J Piper, A G Stewart. Antagonism of vasoconstriction induced by platelet-activating factor in guinea-pig perfused hearts by selective platelet-activating factor receptor antagonists.
British journal of pharmacology.
1987 Apr; 90(4):771-83. doi:
10.1111/j.1476-5381.1987.tb11231.x. [PMID: 3034369] - S B Hwang, M H Lam. Species difference in the specific receptors of platelet activating factor.
Biochemical pharmacology.
1986 Dec; 35(24):4511-8. doi:
10.1016/0006-2952(86)90772-0. [PMID: 3024653]
