2-Methoxyethyl phenyl ether (BioDeep_00000171976)
human metabolite blood metabolite Volatile Flavor Compounds
代谢物信息卡片
Benzene, (2-methoxyethoxy)-
化学式: C9H12O2 (152.0837252)
中文名称: 2-甲氧基乙氧基苯, 2-甲氧基乙基苯基醚
谱图信息:
最多检出来源 Homo sapiens(blood) 8.7%
分子结构信息
SMILES: COCCOC1=CC=CC=C1
InChI: InChI=1S/C9H12O2/c1-10-7-8-11-9-5-3-2-4-6-9/h2-6H,7-8H2,1H3
数据库引用编号
7 个数据库交叉引用编号
- PubChem: 96375
- HMDB: HMDB0243568
- chemspider: 86998
- CAS: 35138-81-9
- CAS: 41532-81-4
- LOTUS: LTS0204943
- wikidata: Q83067156
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Guillermo Rodríguez-Gutiérrez, Garry G Duthie, Sharon Wood, Phil Morrice, Fergus Nicol, Martin Reid, Louise L Cantlay, Thomas Kelder, Graham W Horgan, Juan Fernández-Bolaños Guzmán, Baukje de Roos. Alperujo extract, hydroxytyrosol, and 3,4-dihydroxyphenylglycol are bioavailable and have antioxidant properties in vitamin E-deficient rats--a proteomics and network analysis approach.
Molecular nutrition & food research.
2012 Jul; 56(7):1137-47. doi:
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Stress (Amsterdam, Netherlands).
2012 May; 15(3):354-60. doi:
10.3109/10253890.2011.623249. [PMID: 21995501] - Lanyun Fang, Yan Lv, Xuefei Sheng, Shanshan Yao. Sensitive, rapid and easy analysis of three catecholamine metabolites in human urine and serum by liquid chromatography tandem mass spectrometry.
Journal of chromatographic science.
2012 May; 50(5):450-6. doi:
10.1093/chromsci/bms068. [PMID: 22511488] - Yuki Tokutsu, Wakako Umene-Nakano, Reiji Yoshimura, Asuka Katsuki, Kiyokazu Atake, Jun Nakamura. The case of a depressed man who exhibited hyperprolactinemia and galactopoiesis after electroconvulsive therapy.
The journal of ECT.
2012 Mar; 28(1):56. doi:
10.1097/yct.0b013e31820b846f. [PMID: 21778911] - Maiko Machida, Shigeru Takechi, Tetsuya Fujimoto, Shigeo Kakinoki, Akikazu Nomura. Carvedilol improves uptake-1 in patients with systolic congestive heart failure.
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2012 Feb; 59(2):175-81. doi:
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Physiology & behavior.
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Human psychopharmacology.
2012 Jan; 27(1):33-8. doi:
10.1002/hup.1257. [PMID: 22213405] - Hejun Duan, Na Guan, Yongning Wu, Jing Zhang, Jie Ding, Bing Shao. Identification of biomarkers for melamine-induced nephrolithiasis in young children based on ultra high performance liquid chromatography coupled to time-of-flight mass spectrometry (U-HPLC-Q-TOF/MS).
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2011 May; 879(17-18):1444-56. doi:
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Psychiatry research.
2011 Apr; 186(2-3):326-32. doi:
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European psychiatry : the journal of the Association of European Psychiatrists.
2011 Jan; 26(1):57-63. doi:
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Journal of child neurology.
2011 Jan; 26(1):31-6. doi:
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Journal of psychopharmacology (Oxford, England).
2010 Dec; 24(12):1764-71. doi:
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2010 Dec; 50(12):1420-8. doi:
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2010 Nov; 35(10):1536-42. doi:
10.1016/j.psyneuen.2010.05.008. [PMID: 20576361] - Boubacar Pasto Wann, Marie-Claude Audet, Hymie Anisman. Impact of acute and chronic stressor experiences on heart atrial and brain natriuretic peptides in response to a subsequent stressor.
Hormones and behavior.
2010 Nov; 58(5):907-16. doi:
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2010 Oct; 30(5):496-503. doi:
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American journal of medical genetics. Part A.
2010 Oct; 152A(10):2529-34. doi:
10.1002/ajmg.a.33632. [PMID: 20799318] - Jakob Nyhlén, Radu Constantinescu, Henrik Zetterberg. Problems associated with fluid biomarkers for Parkinson's disease.
Biomarkers in medicine.
2010 Oct; 4(5):671-81. doi:
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Drug development and industrial pharmacy.
2010 Oct; 36(10):1235-44. doi:
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Molecular pharmacology.
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European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology.
2010 Jan; 20(1):18-24. doi:
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Human psychopharmacology.
2009 Dec; 24(8):639-45. doi:
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Clinical chemistry.
2009 Dec; 55(12):2223-4. doi:
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Biological psychiatry.
2009 Oct; 66(8):728-33. doi:
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Biological psychiatry.
2009 Aug; 66(3):287-92. doi:
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2009 Jun; 587(Pt 11):2589-97. doi:
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2009 May; 29(20):6568-79. doi:
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2009 May; 19(5):363-70. doi:
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Talanta.
2009 Apr; 78(1):150-5. doi:
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Parkinsonism & related disorders.
2009 Feb; 15(2):122-7. doi:
10.1016/j.parkreldis.2008.04.002. [PMID: 18514012] - Wakako Umene, Reiji Yoshimura, Hikaru Hori, Hideki Nakano, Atsuko Sugita, Masayuki Shimono, Kenchi Takano, Naoki Shiota, Yoshinori Tomoda, Yukunori Korogi, Jun Nakamura. Blood levels of catecholamine metabolites and brain-derived neurotrophic factor in a case of Sydenham's chorea.
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry.
2009; 10(3):248-51. doi:
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2008 Dec; 258(8):456-62. doi:
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2008 Oct; 11(5):397-403. doi:
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Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.
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Pharmacology, biochemistry, and behavior.
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The New England journal of medicine.
2008 Feb; 358(6):605-14. doi:
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Neuropharmacology.
2008 Feb; 54(2):300-8. doi:
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Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.
2007 Oct; 32(10):2143-51. doi:
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Human psychopharmacology.
2007 Oct; 22(7):483-90. doi:
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Stress (Amsterdam, Netherlands).
2007 Aug; 10(3):295-304. doi:
10.1080/10253890701300904. [PMID: 17613943] - Reiji Yoshimura, Hikaru Hori, Atsuko Sugita, Nobuhisa Ueda, Shingo Kakihara, Wakako Umene, Yuichiro Nakano, Koji Shinkai, Masae Mitoma, Makiko Ohta, Takahiro Shinkai, Jun Nakamura. Treatment with risperidone for 4 weeks increased plasma 3-methoxy-4-hydroxypnenylglycol (MHPG) levels, but did not alter plasma brain-derived neurotrophic factor (BDNF) levels in schizophrenic patients.
Progress in neuro-psychopharmacology & biological psychiatry.
2007 Jun; 31(5):1072-7. doi:
10.1016/j.pnpbp.2007.03.010. [PMID: 17459549] - Reno Gandhi, Shawn Hayley, Julie Gibb, Zul Merali, Hymie Anisman. Influence of poly I:C on sickness behaviors, plasma cytokines, corticosterone and central monoamine activity: moderation by social stressors.
Brain, behavior, and immunity.
2007 May; 21(4):477-89. doi:
10.1016/j.bbi.2006.12.005. [PMID: 17267173] - Reiji Yoshimura. [Treatment of depression from the point of view of suicide prevention].
Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica.
2007; 109(9):822-33. doi:
. [PMID: 18064872] - Hikaru Hori, Reiji Yoshimura, Yasuhisa Yamada, Atsuko Ikenouchi, Masae Mitoma, Yoshishige Ida, Jun Nakamura. Effects of olanzapine on plasma levels of catecholamine metabolites, cytokines, and brain-derived neurotrophic factor in schizophrenic patients.
International clinical psychopharmacology.
2007 Jan; 22(1):21-7. doi:
10.1097/yic.0b013e3280103593. [PMID: 17159456] - Takayoshi Mamiya, Mitsuo Kise, Keiko Morikawa, Hiromichi Aoto, Makoto Ukai, Yukihiro Noda. Effects of pre-germinated brown rice on depression-like behavior in mice.
Pharmacology, biochemistry, and behavior.
2007 Jan; 86(1):62-7. doi:
10.1016/j.pbb.2006.12.008. [PMID: 17258802] - R Yoshimura, K Shinkai, N Ueda, J Nakamura. Valproic acid improves psychotic agitation without influencing plasma risperidone levels in schizophrenic patients.
Pharmacopsychiatry.
2007 Jan; 40(1):9-13. doi:
10.1055/s-2007-958521. [PMID: 17327954] - O Nagy, O Kelemen, G Benedek, C E Myers, D Shohamy, M A Gluck, S Kéri. Dopaminergic contribution to cognitive sequence learning.
Journal of neural transmission (Vienna, Austria : 1996).
2007; 114(5):607-12. doi:
10.1007/s00702-007-0654-3. [PMID: 17347774] - R Yoshimura, N Ueda, K Shinkai, J Nakamura. Two cases of bipolar disorder successfully stabilized for five years with a low dose of risperidone and lithium.
Pharmacopsychiatry.
2006 Nov; 39(6):233-4. doi:
10.1055/s-2006-951386. [PMID: 17124648] - Reiji Yoshimura, Yuichiro Nakano, Hikaru Hori, Atsuko Ikenouchi, Nobuhisa Ueda, Jun Nakamura. Effect of risperidone on plasma catecholamine metabolites and brain-derived neurotrophic factor in patients with bipolar disorders.
Human psychopharmacology.
2006 Oct; 21(7):433-8. doi:
10.1002/hup.804. [PMID: 17029305] - Atsuko Ikenouchi, Reiji Yoshimura, Naomi Ikemura, Kensuke Utsunomiya, Masae Mitoma, Jun Nakamura. Plasma levels of brain derived-neurotrophic factor and catecholamine metabolites are increased during active phase of psychotic symptoms in CNS lupus: a case report.
Progress in neuro-psychopharmacology & biological psychiatry.
2006 Sep; 30(7):1359-63. doi:
10.1016/j.pnpbp.2006.03.006. [PMID: 16626841] - David S Goldstein, Graeme Eisenhofer, Irwin J Kopin. Clinical catecholamine neurochemistry: a legacy of Julius Axelrod.
Cellular and molecular neurobiology.
2006 Jul; 26(4-6):695-702. doi:
10.1007/s10571-006-9041-0. [PMID: 16871444] - Makiko Goto, Reiji Yoshimura, Shingo Kakihara, Koji Shinkai, Yasuhisa Yamada, Kyoko Kaji, Nobuhisa Ueda, Jun Nakamura. Risperidone in the treatment of psychotic depression.
Progress in neuro-psychopharmacology & biological psychiatry.
2006 Jun; 30(4):701-7. doi:
10.1016/j.pnpbp.2006.01.016. [PMID: 16580110] - Ricardo Dávila, Mercedes Zumárraga, Nieves Basterreche, Aurora Arrúe, M Isabel Zamalloa, Juan B Anguiano. Influence of the catechol-O-methyltransferase Val108/158Met polymorphism on the plasma concentration of catecholamine metabolites and on clinical features in type I bipolar disorder--a preliminary report.
Journal of affective disorders.
2006 Jun; 92(2-3):277-81. doi:
10.1016/j.jad.2006.02.009. [PMID: 16542735] - Reiji Yoshimura, Sachiko Kaneko, Koji Shinkai, Jun Nakamura. Successful treatment for obsessive-compulsive disorder with addition of low-dose risperidone to fluvoxamine: implications for plasma levels of catecholamine metabolites and serum brain-derived neurotrophic factor levels.
Psychiatry and clinical neurosciences.
2006 Jun; 60(3):389-93. doi:
10.1111/j.1440-1819.2006.01519.x. [PMID: 16732759] - D S Harris, V I Reus, O Wolkowitz, P Jacob, E T Everhart, M Wilson, J E Mendelson, R T Jones. Catecholamine response to methamphetamine is related to glucocorticoid levels but not to pleasurable subjective response.
Pharmacopsychiatry.
2006 May; 39(3):100-8. doi:
10.1055/s-2006-941483. [PMID: 16721698] - Mikko J Järvisalo, Laura Jartti, Jukka Marniemi, Tapani Rönnemaa, Jorma S A Viikari, Terho Lehtimäki, Olli T Raitakari. Determinants of short-term variation in arterial flow-mediated dilatation in healthy young men.
Clinical science (London, England : 1979).
2006 Apr; 110(4):475-82. doi:
10.1042/cs20050333. [PMID: 16396629] - Alfredo Gamboa, Jorge L Gamboa, Courtney Holmes, Yehonatan Sharabi, Fabiola Leon-Velarde, Gary J Fischman, Otto Appenzeller, David S Goldstein. Plasma catecholamines and blood volume in native Andeans during hypoxia and normoxia.
Clinical autonomic research : official journal of the Clinical Autonomic Research Society.
2006 Feb; 16(1):40-5. doi:
10.1007/s10286-006-0305-z. [PMID: 16477494] - Maiko Machida, Ayumi Sakaguchi, Satoshi Kamada, Tetsuya Fujimoto, Shigeru Takechi, Shigeo Kakinoki, Akikazu Nomura. Simultaneous analysis of human plasma catecholamines by high-performance liquid chromatography with a reversed-phase triacontylsilyl silica column.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2006 Jan; 830(2):249-54. doi:
10.1016/j.jchromb.2005.10.047. [PMID: 16301006] - Jose E Abdenur, Nico Abeling, Norma Specola, Lia Jorge, Andrea B Schenone, Arno C van Cruchten, Nestor A Chamoles. Aromatic l-aminoacid decarboxylase deficiency: unusual neonatal presentation and additional findings in organic acid analysis.
Molecular genetics and metabolism.
2006 Jan; 87(1):48-53. doi:
10.1016/j.ymgme.2005.09.007. [PMID: 16288991] - M Krsek, M Rosická, J Nedvídková, H Kvasnicková, V Hána, J Marek, M Haluzík, E W Lai, K Pacák. Increased lipolysis of subcutaneous abdominal adipose tissue and altered noradrenergic activity in patients with Cushing's syndrome: an in-vivo microdialysis study.
Physiological research.
2006; 55(4):421-428. doi:
10.33549/physiolres.930832. [PMID: 16238457] - S Mata, M Urbina, E Manzano, T Ortiz, L Lima. Noradrenaline transporter and its turnover rate are decreased in blood lymphocytes of patients with major depression.
Journal of neuroimmunology.
2005 Dec; 170(1-2):134-40. doi:
10.1016/j.jneuroim.2005.08.007. [PMID: 16242784] - Nicola Berretta, Peter S Freestone, Ezia Guatteo, Denis de Castro, Raffaella Geracitano, Giorgio Bernardi, Nicola B Mercuri, Janusz Lipski. Acute effects of 6-hydroxydopamine on dopaminergic neurons of the rat substantia nigra pars compacta in vitro.
Neurotoxicology.
2005 Oct; 26(5):869-81. doi:
10.1016/j.neuro.2005.01.014. [PMID: 15890406] - E Sastre, A Nicolay, B Bruguerolle, H Portugal. Effect of lithium on norepinephrine metabolic pathways.
Life sciences.
2005 Jul; 77(7):758-67. doi:
10.1016/j.lfs.2004.12.033. [PMID: 15936350] - Chantal Csajka, Bruno P Imbimbo, Annalisa Piccinno, Philippe Dostert, Davide Verotta. Mechanistic pharmacokinetic and pharmacodynamic modeling of CHF3381 (2-[(2,3-dihydro-1H-inden-2-yl)amino]acetamide monohydrochloride), a novel N-methyl-D-aspartate antagonist and monoamine oxidase-A inhibitor in healthy subjects.
The Journal of pharmacology and experimental therapeutics.
2005 May; 313(2):647-57. doi:
10.1124/jpet.104.080457. [PMID: 15671203] - Simon N Jacob, Chi-Un Choe, Per Uhlen, Brenda DeGray, Mark F Yeckel, Barbara E Ehrlich. Signaling microdomains regulate inositol 1,4,5-trisphosphate-mediated intracellular calcium transients in cultured neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
2005 Mar; 25(11):2853-64. doi:
10.1523/jneurosci.4313-04.2005. [PMID: 15772345] - Shingo Kakihara, Reiji Yoshimura, Koji Shinkai, Chima Matsumoto, Makiko Goto, Kyoko Kaji, Yasuhisa Yamada, Nobuhisa Ueda, Osamu Ohmori, Jun Nakamura. Prediction of response to risperidone treatment with respect to plasma concencentrations of risperidone, catecholamine metabolites, and polymorphism of cytochrome P450 2D6.
International clinical psychopharmacology.
2005 Mar; 20(2):71-8. doi:
10.1097/00004850-200503000-00002. [PMID: 15729081] - Shigeto Yamada. [Assessment of mental condition by saliva level of 3-methoxy-4-hydroxyphenylglycol].
Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica.
2005; 107(7):712-7. doi:
. [PMID: 16146187] - Elena Meli, Roberto Baronti, Marilena Pangallo, Roberta Picca, Flavio Moroni, Domenico E Pellegrini-Giampietro. Group I metabotropic glutamate receptors stimulate the activity of poly(ADP-ribose) polymerase in mammalian mGlu1-transfected cells and in cortical cell cultures.
Neuropharmacology.
2005; 49 Suppl 1(?):80-8. doi:
10.1016/j.neuropharm.2005.05.017. [PMID: 16023154] - David S Goldstein, Courtney Holmes, Horacio Kaufmann, Roy Freeman. Clinical pharmacokinetics of the norepinephrine precursor L-threo-DOPS in primary chronic autonomic failure.
Clinical autonomic research : official journal of the Clinical Autonomic Research Society.
2004 Dec; 14(6):363-8. doi:
10.1007/s10286-004-0221-z. [PMID: 15666063] - Brent M McGrath, Phillip H Wessels, Emily C Bell, Michele Ulrich, Peter H Silverstone. Neurobiological findings in bipolar II disorder compared with findings in bipolar I disorder.
Canadian journal of psychiatry. Revue canadienne de psychiatrie.
2004 Dec; 49(12):794-801. doi:
10.1177/070674370404901202. [PMID: 15679202] - Christoph Schroeder, Jens Tank, David S Goldstein, Michael Stoeter, Sebastian Haertter, Friedrich C Luft, Jens Jordan. Influence of St John's wort on catecholamine turnover and cardiovascular regulation in humans.
Clinical pharmacology and therapeutics.
2004 Nov; 76(5):480-9. doi:
10.1016/j.clpt.2004.08.005. [PMID: 15536462] - Tie-Shan Tang, Huiping Tu, Paul C Orban, Edmond Y W Chan, Michael R Hayden, Ilya Bezprozvanny. HAP1 facilitates effects of mutant huntingtin on inositol 1,4,5-trisphosphate-induced Ca release in primary culture of striatal medium spiny neurons.
The European journal of neuroscience.
2004 Oct; 20(7):1779-87. doi:
10.1111/j.1460-9568.2004.03633.x. [PMID: 15379999] - Margaret Altemus, Jill Fong, Ruirong Yang, Shari Damast, Victoria Luine, Deveroux Ferguson. Changes in cerebrospinal fluid neurochemistry during pregnancy.
Biological psychiatry.
2004 Sep; 56(6):386-92. doi:
10.1016/j.biopsych.2004.06.002. [PMID: 15364035] - Nancy R Keller, André Diedrich, Martin Appalsamy, Sunti Tuntrakool, Suzanna Lonce, Charlene Finney, Marc G Caron, David Robertson. Norepinephrine transporter-deficient mice exhibit excessive tachycardia and elevated blood pressure with wakefulness and activity.
Circulation.
2004 Sep; 110(10):1191-6. doi:
10.1161/01.cir.0000141804.90845.e6. [PMID: 15337696] - Harold W Koenigsberg, Martin H Teicher, Vivian Mitropoulou, Carryl Navalta, Antonia S New, Robert Trestman, Larry J Siever. 24-h Monitoring of plasma norepinephrine, MHPG, cortisol, growth hormone and prolactin in depression.
Journal of psychiatric research.
2004 Sep; 38(5):503-11. doi:
10.1016/j.jpsychires.2004.03.006. [PMID: 15380401] - Orestis Giotakos, Manolis Markianos, Nikos Vaidakis, George N Christodoulou. Sex hormones and biogenic amine turnover of sex offenders in relation to their temperament and character dimensions.
Psychiatry research.
2004 Jul; 127(3):185-93. doi:
10.1016/j.psychres.2003.06.003. [PMID: 15296818] - Reiji Yoshimura, Jun Nakamura, Koji Shinkai, Nobuhisa Ueda. Clinical response to antidepressant treatment and 3-methoxy-4-hydroxyphenylglycol levels: mini review.
Progress in neuro-psychopharmacology & biological psychiatry.
2004 Jul; 28(4):611-6. doi:
10.1016/j.pnpbp.2004.01.008. [PMID: 15276685]