Fungizone (BioDeep_00000171861)
human metabolite blood metabolite
代谢物信息卡片
33-[(4-amino-3,5-dihydroxy-6-methyloxan-2-yl)oxy]-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid
化学式: C47H73NO17 (923.4878248)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1OC(OC2CC3OC(O)(CC(O)C3C(O)=O)CC(O)CC(O)C(O)CCC(O)CC(O)CC(=O)OC(C)C(C)C(O)C(C)C=CC=CC=CC=CC=CC=CC=C2)C(O)C(N)C1O
InChI: InChI=1S/C47H73NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-33(51)22-36(53)35(52)20-19-31(49)21-32(50)23-39(55)62-29(3)28(2)42(27)56/h5-18,27-38,40-44,46,49-54,56-58,61H,19-26,48H2,1-4H3,(H,59,60)
描述信息
同义名列表
7 个代谢物同义名
33-[(4-amino-3,5-dihydroxy-6-methyloxan-2-yl)oxy]-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid; 33-[(4-Amino-3,5-dihydroxy-6-methyloxan-2-yl)oxy]-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylate; Amphotericin b cholesterol dispersion; Amphotericin b colloidal dispersion; Amphotericin; Fungizone; Amphocil
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Francelise Bridi Cavassin, Marcello Mihailenko Chaves Magri, Jose Ernesto Vidal, Fabianne Altruda de Moraes Costa Carlesse, Diego Rodrigues Falci, João Luís Baú-Carneiro, Giovanni Luís Breda, Fábio de Araújo Motta, Cássia Silva de Miranda Godoy, Renata de Bastos Ascenço Soares, Carla Sakuma De Oliveira, Ana Verena Almeida Mendes, Hugo Paz Morales, Patrícia Silva Montes, Mariane Taborda, Caroline Martins Rego, Maíra Araujo Félix, Paula Pacheco Katopodis, Julia Raquel da Silva do Ó, Mirela Pereira Lima Abrão, Talita Teles Teixeira Pereira, Flávio Queiroz-Telles. Effectiveness, Tolerability, and Safety of Different Amphotericin B Formulations in Invasive Fungal Infections: A Multicenter, Retrospective, Observational Study.
Clinical therapeutics.
2024 Apr; 46(4):322-337. doi:
10.1016/j.clinthera.2024.01.011. [PMID: 38403508] - Hendra Saputra, Muhammad Safaat, Pugoh Santoso, Rie Wakabayashi, Masahiro Goto, Toki Taira, Noriho Kamiya. Design of Protease-Responsive Antifungal Liposomal Formulation Decorated with a Lipid-Modified Chitin-Binding Domain.
International journal of molecular sciences.
2024 Mar; 25(7):. doi:
10.3390/ijms25073567. [PMID: 38612381] - ". [Multidisciplinary expert consensus on the clinical rational application of different formulations of amphotericin B (2024 edition)].
Zhonghua nei ke za zhi.
2024 Mar; 63(3):230-257. doi:
10.3760/cma.j.cn112138-20231122-00332. [PMID: 38448188] - Rogayeh Seify, Fahimeh Zahednezhad, Parvin Zakeri-Milani, Hadi Valizadeh. Amphotericin B liposomal formulation: applicable preparation methods, challenges, and tips.
Drug development and industrial pharmacy.
2023 Dec; 49(5):367-376. doi:
10.1080/03639045.2023.2215006. [PMID: 37249553] - Armando Barragán-Reyes, Luis Esaú López Jácome, Diana Perales-Martínez, Alejandra Nava-Ruiz, María de Lourdes García Hernández, Patricia Cornejo-Juárez, Joaquín Rincón-Zuno, Adrián Camacho, Rafael Franco Cendejas, José M Feliciano Guzmán, Norma E Rivera-Martínez, Diego Ontañón-Zurita, Jesús Reséndiz-Sánchez, Eva Juárez-Hernández, Daniel Aguilar-Zapata. Fusariosis in Mexico: A 10-year retrospective series.
Medical mycology.
2023 Dec; 61(12):. doi:
10.1093/mmy/myad112. [PMID: 37944000] - Carlos Ezquer-Garin, Gerardo Aguilar, Rafael Ferriols-Lisart, Manuel Alos-Almiñana. Validated HPLC-UV method for amphotericin B quantification in a critical patient receiving AmBisome and treated with extracorporeal replacement therapies.
Biomedical chromatography : BMC.
2023 Sep; ?(?):e5749. doi:
10.1002/bmc.5749. [PMID: 37727118] - Joris R Delanghe, Jonas Himpe, Jerina Boelens, Dominique Benoit, Bram Gadeyne, Marijn M Speeckaert, Frederick Verbeke. C-reactive protein interacts with amphotericin B liposomes and its potential clinical consequences.
Clinical chemistry and laboratory medicine.
2023 Jan; ?(?):. doi:
10.1515/cclm-2022-1213. [PMID: 36691951] - Letícia Kraft, Victoria Stadler Tasca Ribeiro, Geiziane Aparecida Gonçalves, Paula Hansen Suss, Felipe Francisco Tuon. Comparison of amphotericin B lipid complex, deoxycholate amphotericin B, fluconazole, and anidulafungin activity against Candida albicans biofilm isolated from breakthrough candidemia.
Enfermedades infecciosas y microbiologia clinica (English ed.).
2023 Jan; ?(?):. doi:
10.1016/j.eimce.2022.07.009. [PMID: 36707288] - Cid Manso de Mello Vianna, Gabriela Bittencourt Gonzalez Mosegui, Marcus Paulo da Silva Rodrigues. Cost-effectiveness analysis and budgetary impact of anidulafungin treatment for patients with candidemia and other forms of invasive candidiasis in Brazil.
Revista do Instituto de Medicina Tropical de Sao Paulo.
2023; 65(?):e9. doi:
10.1590/s1678-9946202365009. [PMID: 36722671] - Masato Tashiro, Yoko Obata, Takahiro Takazono, Yuki Ota, Tomotaro Wakamura, Yui Shiozawa, Ai Tsuyuki, Taiga Miyazaki, Tomoya Nishino, Koichi Izumikawa. Association between fluid infusions and the recovery from acute kidney injury in patients administered liposomal amphotericin B: a nationwide observational study.
Renal failure.
2022 Dec; 44(1):282-292. doi:
10.1080/0886022x.2022.2036618. [PMID: 35172680] - Hassan Almarhabi, Essam Al-Asmari, Adeeb Munshi, Fayssal Farahat, Abdulfatah Al-Amri, Hatim Q Almaghraby, Maher Alharbi, Abulhakeem Althaqafi. Invasive mucormycosis in a tertiary care hospital in the western region of Saudi Arabia: 11-year retrospective chart review from 2009 to 2019.
Journal of infection and public health.
2022 Dec; 15(12):1466-1471. doi:
10.1016/j.jiph.2022.11.010. [PMID: 36403403] - Hiromasa Taniguchi, Yugo Ishimime, Kosuke Minamihata, Pugoh Santoso, Takuya Komada, Hendra Saputra, Kazuki Uchida, Masahiro Goto, Toki Taira, Noriho Kamiya. Liposomal Amphotericin B Formulation Displaying Lipid-Modified Chitin-Binding Domains with Enhanced Antifungal Activity.
Molecular pharmaceutics.
2022 11; 19(11):3906-3914. doi:
10.1021/acs.molpharmaceut.2c00388. [PMID: 36066555] - Maksim A Burkin, Yuri A Surovoy, Vera G Arzumanian, Inna A Galvidis. Development and application of amphotericin B immunoassay for pharmacokinetic studies and therapeutic drug monitoring in critically ill patients.
Journal of pharmaceutical and biomedical analysis.
2022 Sep; 218(?):114875. doi:
10.1016/j.jpba.2022.114875. [PMID: 35679709] - Pugoh Santoso, Takuya Komada, Yugo Ishimine, Hiromasa Taniguchi, Kosuke Minamihata, Masahiro Goto, Toki Taira, Noriho Kamiya. Preparation of amphotericin B-loaded hybrid liposomes and the integration of chitin-binding proteins for enhanced antifungal activity.
Journal of bioscience and bioengineering.
2022 Sep; 134(3):259-263. doi:
10.1016/j.jbiosc.2022.06.005. [PMID: 35781189] - X M Ding, Y Y Qi, K Y Zhang, G Tian, S P Bai, J P Wang, H W Peng, L Lv, Y Xuan, Q F Zeng. Corn distiller's dried grains with solubles as an alternative ingredient to corn and soybean meal in Pekin duck diets based on its predicted AME and the evaluated standardized ileal digestibility of amino acids.
Poultry science.
2022 Aug; 101(8):101974. doi:
10.1016/j.psj.2022.101974. [PMID: 35760004] - Amirreza Veisi, Abbas Bagheri, Mohammad Eshaghi, Mohamad Hasan Rikhtehgar, Mozhgan Rezaei Kanavi, Reza Farjad. Rhino-orbital mucormycosis during steroid therapy in COVID-19 patients: A case report.
European journal of ophthalmology.
2022 Jul; 32(4):NP11-NP16. doi:
10.1177/11206721211009450. [PMID: 33843287] - Jonathan P Huggins, Robert Pease, Kelly Stanly, Adrienne Workman, John Reynolds, Barbara D Alexander. Safety of Inhaled Amphotericin B Lipid Complex as Antifungal Prophylaxis in Lung Transplant Recipients.
Antimicrobial agents and chemotherapy.
2022 06; 66(6):e0028322. doi:
10.1128/aac.00283-22. [PMID: 35506698] - Reshma P Chavan, Shivraj M Ingole, Hamna Abdul Nazir, Wilson V Desai, Gajanan S Kanchewad. Mucormycosis in COVID-19 pandemic: study at tertiary hospital in India.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery.
2022 Jun; 279(6):3201-3210. doi:
10.1007/s00405-022-07282-1. [PMID: 35122509] - Rula M Darwish, Mohammad AlMasri, Mahmoud M Al-Masri. Mucormycosis: The hidden and forgotten disease.
Journal of applied microbiology.
2022 Jun; 132(6):4042-4057. doi:
10.1111/jam.15487. [PMID: 35156271] - Bo Wang, Yuerong Wang, Luwen Zhang, Fanbo Lu, Min Zhang, Yuanhong Xu. Surveillance Study of Epidemiology, Antifungal Susceptibility and Risk Factors of Invasive Candidiasis in Critically ill Patients.
Clinical laboratory.
2022 Jun; 68(6):. doi:
10.7754/clin.lab.2021.211001. [PMID: 35704741] - Akshay Gopinathan Nair, Tarjani Vivek Dave. Transcutaneous retrobulbar injection of amphotericin B in rhino-orbital-cerebral mucormycosis: a review.
Orbit (Amsterdam, Netherlands).
2022 Jun; 41(3):275-286. doi:
10.1080/01676830.2021.1990351. [PMID: 34720026] - Pugoh Santoso, Kosuke Minamihata, Yugo Ishimine, Hiromasa Taniguchi, Takuya Komada, Ryo Sato, Masahiro Goto, Tomoya Takashima, Toki Taira, Noriho Kamiya. Enhancement of the Antifungal Activity of Chitinase by Palmitoylation and the Synergy of Palmitoylated Chitinase with Amphotericin B.
ACS infectious diseases.
2022 05; 8(5):1051-1061. doi:
10.1021/acsinfecdis.2c00052. [PMID: 35471825] - Mahzad Erami, Omid Raiesi, Mansooreh Momen-Heravi, Muhammad Ibrahim Getso, Mojtaba Fakhrehi, Narges Mehri, Mohammad Yarahmadi, Sasan Amiri, Vahid Raissi, Seyed Jamal Hashemi. Clinical impact of Candida respiratory tract colonization and acute lung infections in critically ill patients with COVID-19 pneumonia.
Microbial pathogenesis.
2022 May; 166(?):105520. doi:
10.1016/j.micpath.2022.105520. [PMID: 35405278] - Lais Alonso, Laryssa Ketelyn Lima Pimenta, André Kipnis, Antonio Alonso. Mycobacterium abscessus cell wall and plasma membrane characterization by EPR spectroscopy and effects of amphotericin B, miltefosine and nerolidol.
Biochimica et biophysica acta. Biomembranes.
2022 05; 1864(5):183872. doi:
10.1016/j.bbamem.2022.183872. [PMID: 35085568] - Sumit Mrig, Kabir Sardana, Pooja Arora, Vineet Narula, Sandeep Arora, Amrit Kapoor, Ritu Raj Baruah, Poornima Sen, Shweta Agarwal, Soumya Sachdeva, Arun Dewan, Sanjeet Panesar. Adjunctive use of saturated solution of potassium iodide (SSKI) with liposomal amphotericin B (L-AMB) in mucormycosis achieves favorable response, shortened dose and duration of amphotericin: A retrospective study from a COVID-19 tertiary care center.
American journal of otolaryngology.
2022 May; 43(3):103465. doi:
10.1016/j.amjoto.2022.103465. [PMID: 35429848] - Wei-Chun Huang, Mei-Tzu Wang, Tai-Shuan Lai, Kuo-Hua Lee, Shih-Chieh Shao, Chien-Hao Chen, Chien-Hao Su, Yih-Ting Chen, Junne-Ming Sung, Yung-Chang Chen. Nephrotoxins and acute kidney injury - The consensus of the Taiwan acute kidney injury Task Force.
Journal of the Formosan Medical Association = Taiwan yi zhi.
2022 May; 121(5):886-895. doi:
10.1016/j.jfma.2021.12.007. [PMID: 34998658] - D Kaushal, N Rajan, K Soni, A Sharma, B Choudhury, T Yadav, P Khera, P Gupta, N Kaur, A Goyal. Reducing mortality in mucormycosis of the head and neck in diabetic patients: A CARE case series.
European annals of otorhinolaryngology, head and neck diseases.
2022 May; 139(3):146-152. doi:
10.1016/j.anorl.2021.06.015. [PMID: 34489194] - Sema Tamer Kaderli, Aylin Karalezli, Burak Ekrem Çitil, Ali Osman Saatci. Endogenous Fungal Endophthalmitis in a Patient Admitted to Intensive Care and Treated with Systemic Steroid for COVID-19.
Turkish journal of ophthalmology.
2022 04; 52(2):139-141. doi:
10.4274/tjo.galenos.2022.04324. [PMID: 35481735] - Yusri Abdel-Hafez, Hani Siaj, Mohammad Janajri, Yazan Abu-Baker, Zaher Nazzal, Zakaria Hamdan, Rabee Adwan, Banan M Aiesh, Ahmad I Anaya. Tolerability and epidemiology of nephrotoxicity associated with conventional amphotericin B therapy: a retrospective study in tertiary care centers in Palestine.
BMC nephrology.
2022 04; 23(1):132. doi:
10.1186/s12882-022-02770-2. [PMID: 35382766] - Xueyuan Zhang, Yuhuan Ji, Jinzhi Liu, Ji Liu, Chunlei Li, Laixin Wang, Min Meng, Limei Zhao. Regulated bioanalysis of liposomal amphotericin B to support pharmacokinetic studies of liposomal drugs.
Bioanalysis.
2022 Apr; 14(7):421-439. doi:
10.4155/bio-2021-0281. [PMID: 35264007] - Prashant Gupta, Hardeep Singh Malhotra, Priyamvada Saxena, Riddhi Singh, Deeksha Shukla, Mohd Saqib Hasan, Veerendra Verma, Gopa Banerjee, Bipin Puri, Himanshu Dandu. Utility of itraconazole and terbinafine in mucormycosis: a proof-of-concept analysis.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research.
2022 04; 70(4):914-918. doi:
10.1136/jim-2021-002179. [PMID: 35078866] - Prabhakar Singh, Abhishek Gupta, Sravani Reddy Sanepalli, Amit Raj. Transcutaneous retrobulbar amphotericin-B (TRAMB) injection in orbital mucormycosis.
BMJ case reports.
2022 Mar; 15(3):. doi:
10.1136/bcr-2021-246307. [PMID: 35361668] - María Cruz Soriano, Gabriela Narváez-Chávez, Marina López-Olivencia, Jesús Fortún, Raúl de Pablo. Inhaled amphotericin B lipid complex for prophylaxis against COVID-19-associated invasive pulmonary aspergillosis.
Intensive care medicine.
2022 03; 48(3):360-361. doi:
10.1007/s00134-021-06603-y. [PMID: 34940907] - Lakshmi B Ramamurthy, Ridhi Bhandari, Savitha Kanakpur, P Thejaswini. Outcome of transcutaneous retrobulbar injection of liposomal amphotericin B in post-COVID-19 rhino-orbito-cerebral mucormycosis: Our experience.
Indian journal of ophthalmology.
2022 03; 70(3):1019-1024. doi:
10.4103/ijo.ijo_2356_21. [PMID: 35225564] - Satish Swain, Animesh Ray, Naveet Wig, Anjan Trikha. Desensitization to liposomal amphotericin B after anaphylaxis in a patient with COVID-19-associated mucormycosis - A case with review of literature.
Indian journal of pharmacology.
2022 Mar; 54(2):150-152. doi:
10.4103/ijp.ijp_883_21. [PMID: 35546469] - Emanuel Paula Magalhães, Brenna Pinheiro Silva, Natália Luna Aires, Lyanna Rodrigues Ribeiro, Arif Ali, Mariana Maciel Cavalcanti, João Victor Serra Nunes, Tiago Lima Sampaio, Ramon Róseo Paula Pessoa Bezerra de Menezes, Alice Maria Costa Martins. (-)-α-Bisabolol as a protective agent against epithelial renal cytotoxicity induced by amphotericin B.
Life sciences.
2022 Feb; 291(?):120271. doi:
10.1016/j.lfs.2021.120271. [PMID: 34974077] - Munazza Tamkeen Fatima, Zeyaul Islam, Ejaj Ahmad, Mehboob Hoque, Marriam Yamin. Plasma Bead Entrapped Liposomes as a Potential Drug Delivery System to Combat Fungal Infections.
Molecules (Basel, Switzerland).
2022 Feb; 27(3):. doi:
10.3390/molecules27031105. [PMID: 35164370] - Rodrigo C Bassi, Marcelo F G Boriollo. Amphotericin B, fluconazole, and nystatin as development inhibitors of Candida albicans biofilms on a dental prosthesis reline material: Analytical models in vitro.
The Journal of prosthetic dentistry.
2022 Feb; 127(2):320-330. doi:
10.1016/j.prosdent.2020.10.018. [PMID: 33279153] - Amrita Chakrabarti, Chintam Narayana, Nishant Joshi, Swati Garg, Lalit C Garg, Anand Ranganathan, Ram Sagar, Soumya Pati, Shailja Singh. Metalloprotease Gp63-Targeting Novel Glycoside Exhibits Potential Antileishmanial Activity.
Frontiers in cellular and infection microbiology.
2022; 12(?):803048. doi:
10.3389/fcimb.2022.803048. [PMID: 35601095] - Max Melchers, Barbara Festen, Bianca M den Dekker, Eline R M Mooren, Annelien L van Binsbergen, Sjoerd H W van Bree, Moniek Heusinkveld, Roel Schellaars, Jochem B Buil, Paul E Verweij, Arthur R H van Zanten. A 67-Year-Old Male Patient With COVID-19 With Worsening Respiratory Function and Acute Kidney Failure.
Chest.
2022 01; 161(1):e5-e11. doi:
10.1016/j.chest.2021.08.045. [PMID: 35000717] - V N Kolesnokov, A A Khanamirov, N V Boiko, M A Lapin, S D Stagniev. [Postcovid sino-orbital mucormycosis: a case report].
Vestnik otorinolaringologii.
2022; 87(3):107-111. doi:
10.17116/otorino202287031107. [PMID: 35818954] - Ramesh Murthy, Aadhyaa Bagchi, Yogita Gote, Sanjay Desai. Retrobulbar injection of amphotericin B using intravenous cannula for post-COVID-19 rhino-orbital mucormycosis.
Indian journal of ophthalmology.
2022 Jan; 70(1):302-305. doi:
10.4103/ijo.ijo_1511_21. [PMID: 34937263] - T H Geersing, E J F Franssen, P E Spronk, H J M van Kan, M den Reijer, P H J van der Voort. Nephrotoxicity of continuous amphotericin B in critically ill patients with abdominal sepsis: a retrospective analysis with propensity score matching.
The Journal of antimicrobial chemotherapy.
2021 12; 77(1):246-252. doi:
10.1093/jac/dkab372. [PMID: 34613383] - N A Kireeva, S S Sokolov, E A Smirnova, K V Galkina, F F Severin, D A Knorre. Adaptive Role of Cell Death in Yeast Communities Stressed with Macrolide Antifungals.
mSphere.
2021 12; 6(6):e0074521. doi:
10.1128/msphere.00745-21. [PMID: 34787448] - Victória Soares Soeiro, Ricardo Silva-Carvalho, Daniela Martins, Pier Parpot, Denise Grotto, Marco Vinicius Chaud, Francisco Miguel Portela da Gama, Angela Faustino Jozala. Alginate-amphotericin B nanocomplexes covered by nanocrystals from bacterial cellulose: physico-chemical characterization and in vitro toxicity.
Scientific reports.
2021 12; 11(1):23944. doi:
10.1038/s41598-021-03264-1. [PMID: 34907234] - Fatma Devrim, İlknur Çağlar, Sultan Okur Acar, Şeyma Akkuş, Nida Dinçel, Ebru Yılmaz, Neryal Tahta, Bengü Demirağ, Tuba Hilkay Karapınar, Salih Gözmen, Yeşim Oymak, Canan Vergin, Nuri Bayram, İlker Devrim. Evaluation of renal effects of liposomal amphotericin B in children with malignancies with KDIGO and RIFLE criteria.
Nephrologie & therapeutique.
2021 Dec; 17(7):507-511. doi:
10.1016/j.nephro.2021.06.007. [PMID: 34535406] - Dorna Derakhshan, Mitra Basiratnia, Ali Derakhshan, Mohammad Hossein Fallahzadeh, Seyed Mohsen Dehghani, Neda Soleimani, Mohammad Hossein Anbardar, Babak Shirazi Yeganeh, Sahand Mohammadzadeh. Concomitant BK virus infection and visceral Leishmaniasis in a pediatric liver transplant recipient.
Pediatric transplantation.
2021 12; 25(8):e14100. doi:
10.1111/petr.14100. [PMID: 34302419] - Agnieszka Lewandowska, Corinne P Soutar, Alexander I Greenwood, Evgeny Nimerovsky, Ashley M De Lio, Jordan T Holler, Grant S Hisao, Anuj Khandelwal, Jiabao Zhang, Anna M SantaMaria, Charles D Schwieters, Taras V Pogorelov, Martin D Burke, Chad M Rienstra. Fungicidal amphotericin B sponges are assemblies of staggered asymmetric homodimers encasing large void volumes.
Nature structural & molecular biology.
2021 12; 28(12):972-981. doi:
10.1038/s41594-021-00685-4. [PMID: 34887566] - Olivier Cointault, Marine Joly, Sophie Cassaing, François Labaste, Chloé Danet, Lydie Porte, Joelle Guitard, Nassim Kamar, Stanislas Faguer. Weekly high-dose liposomal amphotericin B prevents invasive aspergillosis after heart transplantation.
Transplant infectious disease : an official journal of the Transplantation Society.
2021 Dec; 23(6):e13745. doi:
10.1111/tid.13745. [PMID: 34657372] - Ke Peng, Lalitkumar K Vora, Ismaiel A Tekko, Andi Dian Permana, Juan Domínguez-Robles, Delly Ramadon, Philip Chambers, Helen O McCarthy, Eneko Larrañeta, Ryan F Donnelly. Dissolving microneedle patches loaded with amphotericin B microparticles for localised and sustained intradermal delivery: Potential for enhanced treatment of cutaneous fungal infections.
Journal of controlled release : official journal of the Controlled Release Society.
2021 11; 339(?):361-380. doi:
10.1016/j.jconrel.2021.10.001. [PMID: 34619227] - Koteswara R Chintalacharuvu, Zlatko A Matolek, Benny Pacheco, Erick M Carriera, David O Beenhouwer. Complexing amphotericin B with gold nanoparticles improves fungal clearance from the brains of mice infected with Cryptococcal neoformans.
Medical mycology.
2021 Nov; 59(11):1085-1091. doi:
10.1093/mmy/myab042. [PMID: 34332505] - Anusuya Bhattacharyya, Phulen Sarma, Hardeep Kaur, Subodh Kumar, Jaimini Bhattacharyya, Manisha Prajapat, Ajay Prakash, Saurabh Sharma, Dibbanti Harikrishna Reddy, Prasad Thota, Seema Bansal, Bhaswati Sharma Gautam, Bikash Medhi. COVID-19-associated rhino-orbital-cerebral mucormycosis: A systematic review, meta-analysis, and meta-regression analysis.
Indian journal of pharmacology.
2021 Nov; 53(6):499-510. doi:
10.4103/ijp.ijp_839_21. [PMID: 34975140] - Navneet Arora, Ajay Gudipati, Reetu Kundu, Nidhi Prabhakar, Vikas Suri, Pankaj Malhotra, Arihant Jain. Post-COVID-19 mucormycosis presenting as chest wall cellulitis with mediastinitis.
The Lancet. Infectious diseases.
2021 11; 21(11):1611. doi:
10.1016/s1473-3099(21)00582-x. [PMID: 34717815] - A-P Bellanger, J-C Navellou, Q Lepiller, A Brion, A-S Brunel, L Millon, A Berceanu. Mixed mold infection with Aspergillus fumigatus and Rhizopus microsporus in a severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) patient.
Infectious diseases now.
2021 Oct; 51(7):633-635. doi:
10.1016/j.idnow.2021.01.010. [PMID: 33527098] - Shehab Ahmed Alenazi, Ekramy Elmorsy, Ayat Al-Ghafari, Amr El-Husseini. Effect of amphotericin B-deoxycholate (Fungizone) on the mitochondria of Wistar rats' renal proximal tubules cells.
Journal of applied toxicology : JAT.
2021 10; 41(10):1620-1633. doi:
10.1002/jat.4151. [PMID: 33740284] - Farzad Pakdel, Kazem Ahmadikia, Mohammadreza Salehi, Azin Tabari, Rozita Jafari, Golfam Mehrparvar, Yasaman Rezaie, Shahin Rajaeih, Neda Alijani, Aleksandra Barac, Alireza Abdollahi, Sadegh Khodavaisy. Mucormycosis in patients with COVID-19: A cross-sectional descriptive multicentre study from Iran.
Mycoses.
2021 Oct; 64(10):1238-1252. doi:
10.1111/myc.13334. [PMID: 34096653] - Lady Daiane Pereira Leite, Maria Alcionéia Carvalho de Oliveira, Mariana Raquel da Cruz Vegian, Aline da Graça Sampaio, Thalita Mayumi Castaldelli Nishime, Konstantin Georgiev Kostov, Cristiane Yumi Koga-Ito. Effect of Cold Atmospheric Plasma Jet Associated to Polyene Antifungals on Candida albicans Biofilms.
Molecules (Basel, Switzerland).
2021 Sep; 26(19):. doi:
10.3390/molecules26195815. [PMID: 34641359] - Mostafa Alfishawy, Amira Elbendary, Abdelrahman Younes, Ahmed Negm, Walid Shehata Hassan, Safinaz Hassan Osman, Mahmoud Nassar, Mervat G Elanany. Diabetes mellitus and Coronavirus Disease (Covid-19) Associated Mucormycosis (CAM): A wake-up call from Egypt.
Diabetes & metabolic syndrome.
2021 Sep; 15(5):102195. doi:
10.1016/j.dsx.2021.102195. [PMID: 34314921] - Tomoko Ando, Hideaki Kawakami, Kiyofumi Mochizuki, Kazuhiro Murata, Yusuke Manabe, Daisuke Takagi, Ayaka Yagasaki, Yoshiaki Niwa, Noriaki Yamada, Shinji Ogura, Kana Matsumoto, Kunihiko Morita, Daisuke Todokoro, Katsuhiko Kamei. Intraocular penetration of liposomal amphotericin B after intravenous injection in inflamed human eyes.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.
2021 Sep; 27(9):1319-1322. doi:
10.1016/j.jiac.2021.04.020. [PMID: 33994091] - Gokul Krishnan, Nitin Gupta, Kavitha Saravu, Handattu Manjunath Hande, Ruchee Khanna. Deoxycholate amphotericin for histoplasmosis in a patient with poor kidney function.
BMJ case reports.
2021 Aug; 14(8):. doi:
10.1136/bcr-2021-243984. [PMID: 34446514] - Sofie Van Ackerbroeck, Lynn Rutsaert, Ella Roelant, Kathleen Dillen, Joost Wauters, Niels Van Regenmortel. Inhaled liposomal amphotericin-B as a prophylactic treatment for COVID-19-associated pulmonary aspergillosis/aspergillus tracheobronchitis.
Critical care (London, England).
2021 08; 25(1):298. doi:
10.1186/s13054-021-03728-w. [PMID: 34412686] - Adith Venugopal, Anand Marya. Palatal mucormycosis in a patient with SARS-CoV-2 infection.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.
2021 08; 193(32):E1254. doi:
10.1503/cmaj.211026. [PMID: 34400485] - Omar A Alshaya, Rana A Saleh, Shaden D Alshehri. Voriconazole-Induced Hepatotoxicity Resolved after Switching to Amphotericin B in Fusarium dimerum Central Line-Associated Bloodstream Infection.
The American journal of case reports.
2021 Aug; 22(?):e932544. doi:
10.12659/ajcr.932544. [PMID: 34373441] - Megumi Ikura, Tsutomu Nakamura, Takaya Uno, Kazuki Nakagita, Hiromi Takenaka, Sachi Matsuda, Ryosuke Oda, Kyoichi Wada, Yuji Hattori, Osamu Seguchi, Masanobu Yanase, Naoki Hayakawa, Norihide Fukushima. Discontinuation of oral amphotericin B therapy does not influence the pharmacokinetics of tacrolimus in heart transplant patients.
International journal of clinical pharmacology and therapeutics.
2021 Aug; 59(8):566-571. doi:
10.5414/cp204005. [PMID: 34085636] - Kazem Ahmadikia, Seyed Jamal Hashemi, Sadegh Khodavaisy, Muhammad Ibrahim Getso, Neda Alijani, Hamid Badali, Hossein Mirhendi, Mohammadreza Salehi, Azin Tabari, Mojtaba Mohammadi Ardehali, Mohammad Kord, Emmanuel Roilides, Sassan Rezaie. The double-edged sword of systemic corticosteroid therapy in viral pneumonia: A case report and comparative review of influenza-associated mucormycosis versus COVID-19 associated mucormycosis.
Mycoses.
2021 Aug; 64(8):798-808. doi:
10.1111/myc.13256. [PMID: 33590551] - Lais Alonso, Sebastião Antônio Mendanha, Rodrigo Saar Gomes, Miriam Leandro Dorta, Antonio Alonso. Comparative EPR spectroscopy analysis of amphotericin B and miltefosine interactions with Leishmania, erythrocyte and macrophage membranes.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2021 Aug; 163(?):105859. doi:
10.1016/j.ejps.2021.105859. [PMID: 33894283] - Ali Amanati, Parisa Badiee, Hadis Jafarian, Fatemeh Ghasemi, Samane Nematolahi, Sezaneh Haghpanah, Seyedeh Sedigheh Hamzavi. Impact of antifungal stewardship interventions on the susceptibility of colonized Candida species in pediatric patients with malignancy.
Scientific reports.
2021 07; 11(1):14099. doi:
10.1038/s41598-021-93421-3. [PMID: 34238976] - Yuki Ota, Yoko Obata, Takahiro Takazono, Masato Tashiro, Tomotaro Wakamura, Akinori Takahashi, Yui Shiozawa, Taiga Miyazaki, Tomoya Nishino, Koichi Izumikawa. Association between potassium supplementation and the occurrence of acute kidney injury in patients with hypokalemia administered liposomal amphotericin B: a nationwide observational study.
BMC nephrology.
2021 06; 22(1):240. doi:
10.1186/s12882-021-02450-7. [PMID: 34193064] - Philipp Koehler, Matteo Bassetti, Arunaloke Chakrabarti, Sharon C A Chen, Arnaldo Lopes Colombo, Martin Hoenigl, Nikolay Klimko, Cornelia Lass-Flörl, Rita O Oladele, Donald C Vinh, Li-Ping Zhu, Boris Böll, Roger Brüggemann, Jean-Pierre Gangneux, John R Perfect, Thomas F Patterson, Thorsten Persigehl, Jacques F Meis, Luis Ostrosky-Zeichner, P Lewis White, Paul E Verweij, Oliver A Cornely. Defining and managing COVID-19-associated pulmonary aspergillosis: the 2020 ECMM/ISHAM consensus criteria for research and clinical guidance.
The Lancet. Infectious diseases.
2021 06; 21(6):e149-e162. doi:
10.1016/s1473-3099(20)30847-1. [PMID: 33333012] - Gergely Milosevits, Tamás Mészáros, Erik Őrfi, Tamás Bakos, Miklós Garami, Gábor Kovács, László Dézsi, Péter Hamar, Balázs Győrffy, András Szabó, Gábor Szénási, János Szebeni. Complement-mediated hypersensitivity reactions to an amphotericin B-containing lipid complex (Abelcet) in pediatric patients and anesthetized rats: Benefits of slow infusion.
Nanomedicine : nanotechnology, biology, and medicine.
2021 06; 34(?):102366. doi:
10.1016/j.nano.2021.102366. [PMID: 33549818] - Atousa Hakamifard, Marzieh Hashemi, Hamed Fakhim, Shima Aboutalebian, Somayeh Hajiahmadi, Rasoul Mohammadi. Fatal disseminated aspergillosis in an immunocompetent patient with COVID-19 due to Aspergillus ochraceus.
Journal de mycologie medicale.
2021 Jun; 31(2):101124. doi:
10.1016/j.mycmed.2021.101124. [PMID: 33684835] - Sophie H Y Lai, Jaime S Rosa Duque, Brian Hon-Yin Chung, Tom Wai-Hin Chung, Daniel Leung, Ronnie Siu-Lun Ho, Raymand Lee, Rosana W S Poon, Gilbert T Chua, Kai-Ning Cheong, Martin Man Chun Chui, Mianne Lee, Sidney Tam, Andrew Ho Cheuk Him, King-Fai Cheng, Wilson Wai-Shing Ho, Kwok-Yung Yuen, Pamela Lee, Yu-Lung Lau. Invasive cerebral phaeohyphomycosis in a Chinese boy with CARD9 deficiency and showing unique radiological features, managed with surgical excision and antifungal treatment.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.
2021 Jun; 107(?):59-61. doi:
10.1016/j.ijid.2021.04.052. [PMID: 33872781] - N Basaran Mutlu-Agardan, Sukran Yilmaz, Fatma Kaynak Onurdag, Nevin Celebi. Development of effective AmB/AmB-αCD complex double loaded liposomes using a factorial design for systemic fungal infection treatment.
Journal of liposome research.
2021 Jun; 31(2):177-188. doi:
10.1080/08982104.2020.1755980. [PMID: 32290745] - Janet Herrada, Ahmed Gamal, Lisa Long, Sonia P Sanchez, Thomas S McCormick, Mahmoud A Ghannoum. In Vitro and In Vivo Antifungal Activity of AmBisome Compared to Conventional Amphotericin B and Fluconazole against Candida auris.
Antimicrobial agents and chemotherapy.
2021 05; 65(6):. doi:
10.1128/aac.00306-21. [PMID: 33846131] - Yvonne J Burnett, Andrej Spec, Mohamed M Ahmed, William G Powderly, Yasir Hamad. Experience with Liposomal Amphotericin B in Outpatient Parenteral Antimicrobial Therapy.
Antimicrobial agents and chemotherapy.
2021 05; 65(6):. doi:
10.1128/aac.01876-20. [PMID: 33846129] - Louis Dagneaux, Afton K Limberg, Douglas R Osmon, Nelson Leung, Daniel J Berry, Matthew P Abdel. Acute Kidney Injury When Treating Periprosthetic Joint Infections After Total Knee Arthroplasties with Antibiotic-Loaded Spacers: Incidence, Risks, and Outcomes.
The Journal of bone and joint surgery. American volume.
2021 05; 103(9):754-760. doi:
10.2106/jbjs.20.01825. [PMID: 33780403] - Ryan Devine, Megan Douglass, Morgan Ashcraft, Nicole Tayag, Hitesh Handa. Development of Novel Amphotericin B-Immobilized Nitric Oxide-Releasing Platform for the Prevention of Broad-Spectrum Infections and Thrombosis.
ACS applied materials & interfaces.
2021 May; 13(17):19613-19624. doi:
10.1021/acsami.1c01330. [PMID: 33904311] - Pauline Tirelle, Jonathan Breton, Alexandre Kauffmann, Wafa Bahlouli, Clément L'Huillier, Emmeline Salameh, Asma Amamou, Marine Jarbeau, Charlène Guérin, Alexis Goichon, Jean-Claude do Rego, Pierre Déchelotte, David Ribet, Moïse Coëffier. Gut microbiota depletion affects nutritional and behavioral responses to activity-based anorexia model in a sex-dependent manner.
Clinical nutrition (Edinburgh, Scotland).
2021 05; 40(5):2734-2744. doi:
10.1016/j.clnu.2021.04.014. [PMID: 33933739] - Shweta Mallikarjun Revannavar, Supriya P S, Laxminarayana Samaga, Vineeth V K. COVID-19 triggering mucormycosis in a susceptible patient: a new phenomenon in the developing world?.
BMJ case reports.
2021 Apr; 14(4):. doi:
10.1136/bcr-2021-241663. [PMID: 33906877] - Renata Caetano Kuschnir, Leonardo Soares Pereira, Maria Rita Teixeira Dutra, Ludmila de Paula, Maria Luciana Silva-Freitas, Gabriela Corrêa-Castro, Simone da Costa Cruz Silva, Glaucia Cota, Joanna Reis Santos-Oliveira, Alda Maria Da-Cruz. High levels of anti-Leishmania IgG3 and low CD4+ T cells count were associated with relapses in visceral leishmaniasis.
BMC infectious diseases.
2021 Apr; 21(1):369. doi:
10.1186/s12879-021-06051-5. [PMID: 33874901] - Kelli Li, Abid Khan, Sharmistha Mishra, Alice Zhabokritsky. Title Not Available.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.
2021 04; 193(16):E585-E588. doi:
10.1503/cmaj.200825-f. [PMID: 33875468] - José Ramón Azanza Perea. [Liposomal amphotericin B: Clinical pharmacology, pharmacokinetics and pharmacodynamics].
Revista iberoamericana de micologia.
2021 Apr; 38(2):52-55. doi:
10.1016/j.riam.2021.02.004. [PMID: 33992527] - Manuela Spadea, Francesca Carraro, Francesco Saglio, Elena Vassallo, Rosanna Pessolano, Massimo Berger, Carlo Scolfaro, Sergio Grassitelli, Franca Fagioli. Successfully treated severe COVID-19 and invasive aspergillosis in early hematopoietic cell transplantation setting.
Transplant infectious disease : an official journal of the Transplantation Society.
2021 04; 23(2):e13470. doi:
10.1111/tid.13470. [PMID: 32959932] - Hernando Trujillo, Mario Fernández-Ruiz, Eduardo Gutiérrez, Ángel Sevillano, Fernando Caravaca-Fontán, Enrique Morales, Francisco López-Medrano, José María Aguado, Manuel Praga, Amado Andrés. Invasive pulmonary aspergillosis associated with COVID-19 in a kidney transplant recipient.
Transplant infectious disease : an official journal of the Transplantation Society.
2021 Apr; 23(2):e13501. doi:
10.1111/tid.13501. [PMID: 33185971] - N Yamada, W Murata, Y Yamaguchi, K-I Fujita, A Ogita, T Tanaka. Enhancing the fungicidal activity of amphotericin B via vacuole disruption by benzyl isothiocyanate, a cruciferous plant constituent.
Letters in applied microbiology.
2021 Apr; 72(4):390-398. doi:
10.1111/lam.13425. [PMID: 33128810] - Jakub Suchodolski, Daria Derkacz, Przemysław Bernat, Anna Krasowska. Capric acid secreted by Saccharomyces boulardii influences the susceptibility of Candida albicans to fluconazole and amphotericin B.
Scientific reports.
2021 03; 11(1):6519. doi:
10.1038/s41598-021-86012-9. [PMID: 33753842] - Ruth Van Daele, Yvo de Beer, Sander Croes, Rob Aarnoutse, Joost Wauters, Johan Maertens, Isabel Spriet, Roger J Brüggemann. Ultra-performance liquid chromatography for quantification of amphotericin B plasma concentrations after use of liposomal amphotericin B.
The Journal of antimicrobial chemotherapy.
2021 03; 76(4):961-966. doi:
10.1093/jac/dkaa515. [PMID: 33351897] - Andrew A Voak, Andy Harris, Jose Miguel Coteron-Lopez, Iñigo Angulo-Barturen, Santiago Ferrer-Bazaga, Simon L Croft, Karin Seifert. Pharmacokinetic / pharmacodynamic relationships of liposomal amphotericin B and miltefosine in experimental visceral leishmaniasis.
PLoS neglected tropical diseases.
2021 03; 15(3):e0009013. doi:
10.1371/journal.pntd.0009013. [PMID: 33651812] - Luana Pereira Borba-Santos, Marcio Nucci, Antonio Ferreira-Pereira, Sonia Rozental. Anti-Sporothrix activity of ibuprofen combined with antifungal.
Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology].
2021 Mar; 52(1):101-106. doi:
10.1007/s42770-020-00327-9. [PMID: 32617835] - Yoko Obata, Takahiro Takazono, Masato Tashiro, Yuki Ota, Tomotaro Wakamura, Akinori Takahashi, Kumiko Sato, Taiga Miyazaki, Tomoya Nishino, Koichi Izumikawa. The clinical usage of liposomal amphotericin B in patients receiving renal replacement therapy in Japan: a nationwide observational study.
Clinical and experimental nephrology.
2021 Mar; 25(3):279-287. doi:
10.1007/s10157-020-01989-3. [PMID: 33179180] - Dong Wang, Wei Zhang, Jie-Xi Ju, Lu-Jia Wang, Ru-Yu Huang, Yan-Fang Xu, Hai-Lin Zhang, Jin-Long Qi. Gender differences in acute toxicity, toxicokinetic and tissue distribution of amphotericin B liposomes in rats.
Toxicology letters.
2021 Mar; 338(?):78-84. doi:
10.1016/j.toxlet.2020.12.004. [PMID: 33309996] - Minoru Yoshida, Kazuo Tamura, Toru Masaoka, Eiji Nakajo. A real-world prospective observational study on the efficacy and safety of liposomal amphotericin B in 426 patients with persistent neutropenia and fever.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.
2021 Feb; 27(2):277-283. doi:
10.1016/j.jiac.2020.10.005. [PMID: 33109439] - R Díaz de León-Ortega, D M D'Arcy, D A Lamprou, W F Xue, N Fotaki. In vitro in vivo relations for the parenteral liposomal formulation of Amphotericin B: A biorelevant and clinically relevant approach.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
2021 Feb; 159(?):188-197. doi:
10.1016/j.ejpb.2020.07.025. [PMID: 32717384] - Naruemit Sayabovorn, Piriyaporn Chongtrakool, Methee Chayakulkeeree. Cryptococcal fungemia and Mycobacterium haemophilum cellulitis in a patient receiving ruxolitinib: a case report and literature review.
BMC infectious diseases.
2021 Jan; 21(1):27. doi:
10.1186/s12879-020-05703-2. [PMID: 33413168] - Baifa Sheng, Yihui Chen, Lihua Sun, Peng Xu, Ben Han, Xiaolong Li, Jiuheng Yin, Teming Li, Haidi Guan, Shuaishuai Chen, Qi Wang, Chuangen Li, Shiqiang Li, Xianhong Jiang, Peng Wang, Qiuyue He, Yong Wang, Weidong Xiao, Hua Yang. Antifungal Treatment Aggravates Sepsis through the Elimination of Intestinal Fungi.
Oxidative medicine and cellular longevity.
2021; 2021(?):2796700. doi:
10.1155/2021/2796700. [PMID: 34707775] - Adeyemi O Adedeji, Yi-Zhong Gu, Tony Pourmohamad, Justin Kanerva, Yafei Chen, Elnaz Atabakhsh, Michael R Tackett, Feifei Chen, Bhavana Bhatt, Thierry Gury, Olivier Dorchies, Manisha Sonee, Michelle Morgan, Jennifer Burkey, Jean-Charles Gautier, James E McDuffie. The Utility of Novel Urinary Biomarkers in Mice for Drug Development Studies.
International journal of toxicology.
2021 Jan; 40(1):15-25. doi:
10.1177/1091581820970498. [PMID: 33161787] - L Nemati Shizari, N Mohammadpour Dounighi, M Bayat, N Mosavari. A New Amphotericin B-loaded Trimethyl Chitosan Nanoparticles as a Drug Delivery System and Antifungal Activity on Candida albicans Biofilm.
Archives of Razi Institute.
2021; 76(3):571-586. doi:
10.22092/ari.2020.342702.1477. [PMID: 34824750] - Abdulrahman A Alduraywish. Case Report: Diabetic urinary auto-brewery and review of literature.
F1000Research.
2021; 10(?):407. doi:
10.12688/f1000research.52461.1. [PMID: 35284058] - Huanhuan Qi, Xin Li, Yuancheng Chen, Xueyuan Zhang, Meng Yang, Cancan Li, Hao Feng, Jing Zhang, Chunlei Li. Pharmacokinetic and pharmacodynamic profiling of generic amphotericin B colloidal dispersion in a rat model of invasive candidiasis.
Journal of global antimicrobial resistance.
2020 12; 23(?):113-119. doi:
10.1016/j.jgar.2020.08.019. [PMID: 32890838]