necrosulfonamide (BioDeep_00000017123)
代谢物信息卡片
化学式: C18H15N5O6S2 (461.0464)
中文名称: 坏死磺酰胺
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: COC1=NC=CN=C1NS(=O)(=O)C2=CC=C(C=C2)NC(=O)C=CC3=CC=C(S3)[N+](=O)[O-]
InChI: InChI=1S/C18H15N5O6S2/c1-29-18-17(19-10-11-20-18)22-31(27,28)14-6-2-12(3-7-14)21-15(24)8-4-13-5-9-16(30-13)23(25)26/h2-11H,1H3,(H,19,22)(H,21,24)/b8-4+
数据库引用编号
6 个数据库交叉引用编号
- ChEBI: CHEBI:63770
- KEGG: C72449
- PubChem: 1566236
- ChEMBL: CHEMBL3220918
- CAS: 1360614-48-7
- CAS: 432531-71-0
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- Lynda Aoudjehane, Jérémie Gautheron, Wilfried Le Goff, Claire Goumard, Julia Gilaizeau, Chan Sonavine Nget, Eric Savier, Muhammad Atif, Philippe Lesnik, Romain Morichon, Yves Chrétien, Yvon Calmus, Olivier Scatton, Chantal Housset, Filomena Conti. Novel defatting strategies reduce lipid accumulation in primary human culture models of liver steatosis.
Disease models & mechanisms.
2020 04; 13(4):. doi:
10.1242/dmm.042663. [PMID: 32094147] - Amine Majdi, Lynda Aoudjehane, Vlad Ratziu, Tawhidul Islam, Marta B Afonso, Filomena Conti, Taïeb Mestiri, Marie Lagouge, Fabienne Foufelle, Florine Ballenghien, Tatiana Ledent, Marthe Moldes, Axelle Cadoret, Laura Fouassier, Jean-Louis Delaunay, Tounsia Aït-Slimane, Gilles Courtois, Bruno Fève, Olivier Scatton, Carina Prip-Buus, Cecília M P Rodrigues, Chantal Housset, Jérémie Gautheron. Inhibition of receptor-interacting protein kinase 1 improves experimental non-alcoholic fatty liver disease.
Journal of hepatology.
2020 04; 72(4):627-635. doi:
10.1016/j.jhep.2019.11.008. [PMID: 31760070] - Zongliang Lu, Changpeng Wu, Mingxing Zhu, Wei Song, He Wang, Jiajia Wang, Jing Guo, Na Li, Jie Liu, Yanwu Li, Hongxia Xu. Ophiopogonin D' induces RIPK1‑dependent necroptosis in androgen‑dependent LNCaP prostate cancer cells.
International journal of oncology.
2020 Feb; 56(2):439-447. doi:
10.3892/ijo.2019.4945. [PMID: 31894265] - Ho Man Tang, Peter Chi Keung Cheung. Gallic Acid Triggers Iron-Dependent Cell Death with Apoptotic, Ferroptotic, and Necroptotic Features.
Toxins.
2019 08; 11(9):. doi:
10.3390/toxins11090492. [PMID: 31455047] - Andrew C Y Lee, Anna J X Zhang, Hin Chu, Can Li, Houshun Zhu, Winger W N Mak, Yanxia Chen, Kin-Hang Kok, Kelvin K W To, Kwok-Yung Yuen. H7N9 influenza A virus activation of necroptosis in human monocytes links innate and adaptive immune responses.
Cell death & disease.
2019 06; 10(6):442. doi:
10.1038/s41419-019-1684-0. [PMID: 31165725] - Jun-Kai Yan, Wei-Hui Yan, Wei Cai. Fish oil-derived lipid emulsion induces RIP1-dependent and caspase 8-licensed necroptosis in IEC-6 cells through overproduction of reactive oxygen species.
Lipids in health and disease.
2018 Jun; 17(1):148. doi:
10.1186/s12944-018-0786-5. [PMID: 29935529] - Yongxiang Wang, Jingcheng Wang, Hua Wang, Xinmin Feng, Yuping Tao, Jiandong Yang, Jun Cai. Necrosulfonamide Attenuates Spinal Cord Injury via Necroptosis Inhibition.
World neurosurgery.
2018 Jun; 114(?):e1186-e1191. doi:
10.1016/j.wneu.2018.03.174. [PMID: 29614353] - R S Al-Lamki, W Lu, P Manalo, J Wang, A Y Warren, A M Tolkovsky, J S Pober, J R Bradley. Tubular epithelial cells in renal clear cell carcinoma express high RIPK1/3 and show increased susceptibility to TNF receptor 1-induced necroptosis.
Cell death & disease.
2016 06; 7(6):e2287. doi:
10.1038/cddis.2016.184. [PMID: 27362805]
